Skip to main content
Top
Published in: Implementation Science 1/2015

Open Access 01-12-2015 | Research

Explaining outcomes in major system change: a qualitative study of implementing centralised acute stroke services in two large metropolitan regions in England

Authors: Naomi J. Fulop, Angus I. G. Ramsay, Catherine Perry, Ruth J. Boaden, Christopher McKevitt, Anthony G. Rudd, Simon J. Turner, Pippa J. Tyrrell, Charles D. A. Wolfe, Stephen Morris

Published in: Implementation Science | Issue 1/2015

Login to get access

Abstract

Background

Implementing major system change in healthcare is not well understood. This gap may be addressed by analysing change in terms of interrelated components identified in the implementation literature, including decision to change, intervention selection, implementation approaches, implementation outcomes, and intervention outcomes.

Methods

We conducted a qualitative study of two cases of major system change: the centralisation of acute stroke services in Manchester and London, which were associated with significantly different implementation outcomes (fidelity to referral pathway) and intervention outcomes (provision of evidence-based care, patient mortality). We interviewed stakeholders at national, pan-regional, and service-levels (n = 125) and analysed 653 documents. Using a framework developed for this study from the implementation science literature, we examined factors influencing implementation approaches; how these approaches interacted with the models selected to influence implementation outcomes; and their relationship to intervention outcomes.

Results

London and Manchester’s differing implementation outcomes were influenced by the different service models selected and implementation approaches used. Fidelity to the referral pathway was higher in London, where a ‘simpler’, more inclusive model was used, implemented with a ‘big bang’ launch and ‘hands-on’ facilitation by stroke clinical networks. In contrast, a phased approach of a more complex pathway was used in Manchester, and the network acted more as a platform to share learning. Service development occurred more uniformly in London, where service specifications were linked to financial incentives, and achieving standards was a condition of service launch, in contrast to Manchester. ‘Hands-on’ network facilitation, in the form of dedicated project management support, contributed to achievement of these standards in London; such facilitation processes were less evident in Manchester.

Conclusions

Using acute stroke service centralisation in London and Manchester as an example, interaction between model selected and implementation approaches significantly influenced fidelity to the model. The contrasting implementation outcomes may have affected differences in provision of evidence-based care and patient mortality. The framework used in this analysis may support planning and evaluating major system changes, but would benefit from application in different healthcare contexts.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kitson AL, Rycroft-Malone J, Harvey G, McCormack B, Seers K, Titchen A. Evaluating the successful implementation of evidence into practice using the PARiHS framework: theoretical and practical challenges. Implement Sci. 2008;3:1.CrossRefPubMedPubMedCentral Kitson AL, Rycroft-Malone J, Harvey G, McCormack B, Seers K, Titchen A. Evaluating the successful implementation of evidence into practice using the PARiHS framework: theoretical and practical challenges. Implement Sci. 2008;3:1.CrossRefPubMedPubMedCentral
3.
go back to reference Pronovost P, Goeschel C, Marsteller J, Sexton J, Pham J, Berenholtz S. Framework for patient safety research and improvement. Circulation. 2009;119:330.CrossRefPubMed Pronovost P, Goeschel C, Marsteller J, Sexton J, Pham J, Berenholtz S. Framework for patient safety research and improvement. Circulation. 2009;119:330.CrossRefPubMed
4.
go back to reference Proctor E, Silmere H, Raghavan R, Hovmand P, Aarons G, Bunger A, et al. Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda. Adm Policy Ment Health. 2011;38:65–76.CrossRefPubMed Proctor E, Silmere H, Raghavan R, Hovmand P, Aarons G, Bunger A, et al. Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda. Adm Policy Ment Health. 2011;38:65–76.CrossRefPubMed
5.
go back to reference Stetler CB, Legro MW, Wallace CM, Bowman C, Guihan M, Hagedorn H, et al. The role of formative evaluation in implementation research and the QUERI experience. J Gen Intern Med. 2006;21:S1–8.CrossRefPubMedPubMedCentral Stetler CB, Legro MW, Wallace CM, Bowman C, Guihan M, Hagedorn H, et al. The role of formative evaluation in implementation research and the QUERI experience. J Gen Intern Med. 2006;21:S1–8.CrossRefPubMedPubMedCentral
6.
go back to reference Mendel P, Meredith LS, Schoenbaum M, Sherbourne CD, Wells KB. Interventions in organizational and community context: a framework for building evidence on dissemination and implementation in health services research. Adm Policy Ment Health. 2008;35:21–37.CrossRefPubMed Mendel P, Meredith LS, Schoenbaum M, Sherbourne CD, Wells KB. Interventions in organizational and community context: a framework for building evidence on dissemination and implementation in health services research. Adm Policy Ment Health. 2008;35:21–37.CrossRefPubMed
8.
9.
go back to reference Graham ID, Logan J, Harrison MB, Straus SE, Tetroe J, Caswell W, et al. Lost in knowledge translation: time for a map? J Contin Educ. 2006;26:13–24.CrossRef Graham ID, Logan J, Harrison MB, Straus SE, Tetroe J, Caswell W, et al. Lost in knowledge translation: time for a map? J Contin Educ. 2006;26:13–24.CrossRef
10.
go back to reference Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:50.CrossRefPubMedPubMedCentral Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:50.CrossRefPubMedPubMedCentral
12.
go back to reference Tabak RG, Khoong EC, Chambers DA, Brownson RC. Bridging research and practice: models for dissemination and implementation research. Am J Prev Med. 2012;43:337–50.CrossRefPubMedPubMedCentral Tabak RG, Khoong EC, Chambers DA, Brownson RC. Bridging research and practice: models for dissemination and implementation research. Am J Prev Med. 2012;43:337–50.CrossRefPubMedPubMedCentral
13.
go back to reference Davidoff F, Dixon-Woods M, Leviton L, Michie S. Demystifying theory and its use in improvement. BMJ Qual Saf. 2015;24:bmjqs-2014-003627.CrossRef Davidoff F, Dixon-Woods M, Leviton L, Michie S. Demystifying theory and its use in improvement. BMJ Qual Saf. 2015;24:bmjqs-2014-003627.CrossRef
14.
go back to reference Imison C, Sonola L, Honeyman M, Ross S. The reconfiguration of clinical services in the NHS: what is the evidence? London: King's Fund; 2014. Imison C, Sonola L, Honeyman M, Ross S. The reconfiguration of clinical services in the NHS: what is the evidence? London: King's Fund; 2014.
15.
go back to reference Fulop N, Boaden R, Hunter R, McKevitt C, Morris S, Pursani N, et al. Innovations in major system reconfiguration in England: a study of the effectiveness, acceptability and processes of implementation of two models of stroke care. Implement Sci. 2013;8:5. doi:10.1186/1748-5908-8-5.CrossRefPubMedPubMedCentral Fulop N, Boaden R, Hunter R, McKevitt C, Morris S, Pursani N, et al. Innovations in major system reconfiguration in England: a study of the effectiveness, acceptability and processes of implementation of two models of stroke care. Implement Sci. 2013;8:5. doi:10.​1186/​1748-5908-8-5.CrossRefPubMedPubMedCentral
16.
go back to reference Fulop N, Walters R, Perri, Spurgeon P. Implementing changes to hospital services: factors influencing the process and ‘results’ of reconfiguration. Health Policy. 2012;104:128–35.CrossRefPubMed Fulop N, Walters R, Perri, Spurgeon P. Implementing changes to hospital services: factors influencing the process and ‘results’ of reconfiguration. Health Policy. 2012;104:128–35.CrossRefPubMed
17.
go back to reference Prabhakaran S, O’Neill K, Stein-Spencer L, Walter J, Alberts MJ. Prehospital triage to primary stroke centers and rate of stroke thrombolysis. JAMA Neurol. 2013;70:1126–32.CrossRefPubMed Prabhakaran S, O’Neill K, Stein-Spencer L, Walter J, Alberts MJ. Prehospital triage to primary stroke centers and rate of stroke thrombolysis. JAMA Neurol. 2013;70:1126–32.CrossRefPubMed
18.
go back to reference Smith EE, Dreyer P, Prvu-Bettger J, Abdullah AR, Palmeri G, Goyette L, et al. Stroke center designation can be achieved by small hospitals: the Massachusetts experience. Crit Pathw Cardiol. 2008;7:173–7.CrossRefPubMed Smith EE, Dreyer P, Prvu-Bettger J, Abdullah AR, Palmeri G, Goyette L, et al. Stroke center designation can be achieved by small hospitals: the Massachusetts experience. Crit Pathw Cardiol. 2008;7:173–7.CrossRefPubMed
19.
20.
go back to reference Lahr MM, Luijckx G-J, Vroomen PC, van der Zee D-J, Buskens E. Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting. Stroke. 2012;43:1336–40.CrossRefPubMed Lahr MM, Luijckx G-J, Vroomen PC, van der Zee D-J, Buskens E. Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting. Stroke. 2012;43:1336–40.CrossRefPubMed
21.
go back to reference Bruins Slot K, Murray V, Boysen G, Berge E. Thrombolytic treatment for stroke in the Scandinavian countries. Acta Neurol Scand. 2009;120:270–6.CrossRefPubMed Bruins Slot K, Murray V, Boysen G, Berge E. Thrombolytic treatment for stroke in the Scandinavian countries. Acta Neurol Scand. 2009;120:270–6.CrossRefPubMed
22.
go back to reference Cadilhac DA, Purvis T, Kilkenny MF, Longworth M, Mohr K, Pollack M, et al. Evaluation of rural stroke services: does implementation of coordinators and pathways improve care in rural hospitals? Stroke. 2013;44:2848–53.CrossRefPubMed Cadilhac DA, Purvis T, Kilkenny MF, Longworth M, Mohr K, Pollack M, et al. Evaluation of rural stroke services: does implementation of coordinators and pathways improve care in rural hospitals? Stroke. 2013;44:2848–53.CrossRefPubMed
23.
go back to reference Sampalis JS, Denis R, Lavoie A, Frechette P, Boukas S, Nikolis A, et al. Trauma care regionalization: a process-outcome evaluation. J Trauma Acute Care Surg. 1999;46:565–81.CrossRef Sampalis JS, Denis R, Lavoie A, Frechette P, Boukas S, Nikolis A, et al. Trauma care regionalization: a process-outcome evaluation. J Trauma Acute Care Surg. 1999;46:565–81.CrossRef
24.
go back to reference Mullins RJ, Mann NC. Population-based research assessing the effectiveness of trauma systems. J Trauma Acute Care Surg. 1999;47:S59–66.CrossRef Mullins RJ, Mann NC. Population-based research assessing the effectiveness of trauma systems. J Trauma Acute Care Surg. 1999;47:S59–66.CrossRef
25.
go back to reference MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, et al. A national evaluation of the effect of trauma-center care on mortality. N Engl J Med. 2006;354:366–78.CrossRefPubMed MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, et al. A national evaluation of the effect of trauma-center care on mortality. N Engl J Med. 2006;354:366–78.CrossRefPubMed
26.
go back to reference Grumbach K, Anderson GM, Luft HS, Roos LL, Brook R. Regionalization of cardiac surgery in the United States and Canada: geographic access, choice, and outcomes. JAMA. 1995;274:1282–8.CrossRefPubMed Grumbach K, Anderson GM, Luft HS, Roos LL, Brook R. Regionalization of cardiac surgery in the United States and Canada: geographic access, choice, and outcomes. JAMA. 1995;274:1282–8.CrossRefPubMed
27.
go back to reference Shah V, Warre R, Lee SK. Quality improvement initiatives in neonatal intensive care unit networks: achievements and challenges. Acad Pediatr. 2013;13:S75–83.CrossRefPubMed Shah V, Warre R, Lee SK. Quality improvement initiatives in neonatal intensive care unit networks: achievements and challenges. Acad Pediatr. 2013;13:S75–83.CrossRefPubMed
28.
go back to reference Morris S, Hunter RM, Ramsay AIG, Boaden R, McKevitt C, Perry C, et al. Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis. BMJ. 2014;349:g4757.CrossRefPubMedPubMedCentral Morris S, Hunter RM, Ramsay AIG, Boaden R, McKevitt C, Perry C, et al. Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis. BMJ. 2014;349:g4757.CrossRefPubMedPubMedCentral
30.
go back to reference National Institute for Health and Clinical Excellence. Stroke: diagnosis and initial management of acute stroke and transient ischaemic attack (TIA): NICE. 2008. National Institute for Health and Clinical Excellence. Stroke: diagnosis and initial management of acute stroke and transient ischaemic attack (TIA): NICE. 2008.
31.
go back to reference Intercollegiate Stroke Working Party. National clinical guideline for stroke. 4th ed. London: Royal College of Physicians; 2012. Intercollegiate Stroke Working Party. National clinical guideline for stroke. 4th ed. London: Royal College of Physicians; 2012.
32.
go back to reference Turner S, Ramsay AI, Perry C, Boaden RJ, Mckevitt C, Morris S, et al. Lessons for major system change: centralisation of stroke services in two metropolitan areas of England. J Health Serv Res Policy. 2016. doi:10.1177/1355819615626189.PubMedCentral Turner S, Ramsay AI, Perry C, Boaden RJ, Mckevitt C, Morris S, et al. Lessons for major system change: centralisation of stroke services in two metropolitan areas of England. J Health Serv Res Policy. 2016. doi:10.​1177/​1355819615626189​.PubMedCentral
33.
go back to reference Department of Health. National stroke strategy. London: Crown; 2007. Department of Health. National stroke strategy. London: Crown; 2007.
34.
go back to reference Foy R, Sales A, Wensing M, Aarons GA, Flottorp S, Kent B, et al. Implementation science: a reappraisal of our journal mission and scope. Implement Sci. 2015;10:51.CrossRefPubMedPubMedCentral Foy R, Sales A, Wensing M, Aarons GA, Flottorp S, Kent B, et al. Implementation science: a reappraisal of our journal mission and scope. Implement Sci. 2015;10:51.CrossRefPubMedPubMedCentral
36.
go back to reference Bradley EH, Curry LA, Devers KJ. Qualitative data analysis for health services research: developing taxonomy, themes, and theory. Health Serv Res. 2007;42:1758–72.CrossRefPubMedPubMedCentral Bradley EH, Curry LA, Devers KJ. Qualitative data analysis for health services research: developing taxonomy, themes, and theory. Health Serv Res. 2007;42:1758–72.CrossRefPubMedPubMedCentral
38.
go back to reference Greater Manchester and Cheshire Stroke Network Support Team. Development of stroke services in Greater Manchester: twelve month review. Manchester: Greater Manchester and Cheshire Cardiac and Stroke Network; 2011. Greater Manchester and Cheshire Stroke Network Support Team. Development of stroke services in Greater Manchester: twelve month review. Manchester: Greater Manchester and Cheshire Cardiac and Stroke Network; 2011.
39.
go back to reference McNulty T, Ferlie E. Process transformation: Limitations to radical organizational change within public service organizations. Organ Stud. 2004;25:1389–412.CrossRef McNulty T, Ferlie E. Process transformation: Limitations to radical organizational change within public service organizations. Organ Stud. 2004;25:1389–412.CrossRef
Metadata
Title
Explaining outcomes in major system change: a qualitative study of implementing centralised acute stroke services in two large metropolitan regions in England
Authors
Naomi J. Fulop
Angus I. G. Ramsay
Catherine Perry
Ruth J. Boaden
Christopher McKevitt
Anthony G. Rudd
Simon J. Turner
Pippa J. Tyrrell
Charles D. A. Wolfe
Stephen Morris
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Implementation Science / Issue 1/2015
Electronic ISSN: 1748-5908
DOI
https://doi.org/10.1186/s13012-016-0445-z

Other articles of this Issue 1/2015

Implementation Science 1/2015 Go to the issue