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Published in: Implementation Science 1/2015

Open Access 01-12-2015 | Research

Bridging the gap between pragmatic intervention design and theory: using behavioural science tools to modify an existing quality improvement programme to implement “Sepsis Six”

Authors: Siri H. Steinmo, Susan Michie, Christopher Fuller, Sarah Stanley, Caitriona Stapleton, Sheldon P. Stone

Published in: Implementation Science | Issue 1/2015

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Abstract

Background

Sepsis has a mortality rate of 40 %, which can be halved if the evidence-based “Sepsis Six” care bundle is implemented within 1 h. UK audit shows low implementation rates. Interventions to improve this have had minimal effects. Quality improvement programmes could be further developed by using theoretical frameworks (Theoretical Domains Framework (TDF)) to modify existing interventions by identifying influences on clinical behaviour and selecting appropriate content. The aim of this study was to illustrate using this process to modify an intervention designed using plan-do-study-act (P-D-S-A) cycles that had achieved partial success in improving Sepsis Six implementation in one hospital.

Methods

Factors influencing implementation were investigated using the TDF to analyse interviews with 34 health professionals. The nursing team who developed and facilitated the intervention used the data to select modifications using the Behaviour Change Technique (BCT) Taxonomy (v1) and the APEASE criteria: affordability, practicability, effectiveness, acceptability, safety and equity.

Results

Five themes were identified as influencing implementation and guided intervention modification. These were:(1) “knowing what to do and why” (TDF domains knowledge, social/professional role and identity); (2) “risks and benefits” (beliefs about consequences), e.g. fear of harming patients through fluid overload acting as a barrier to implementation versus belief in the bundle’s effectiveness acting as a lever to implementation; (3) “working together” (social influences, social/professional role and identity), e.g. team collaboration acting as a lever versus doctor/nurse conflict acting as a barrier; (4) “empowerment and support” (beliefs about capabilities, social/professional role and identity, behavioural regulation, social influences), e.g. involving staff in intervention development acting as a lever versus lack of confidence to challenge colleagues’ decisions not to implement acting as a barrier; (5) “staffing levels” (environmental context and resources), e.g. shortages of doctors at night preventing implementation.
The modified intervention included six new BCTs and consisted of two additional components (Sepsis Six training for the Hospital at Night Co-ordinator; a partnership agreement endorsing engagement of all clinical staff and permitting collegial challenge) and modifications to two existing components (staff education sessions; documents and materials).

Conclusions

This work demonstrates the feasibility of the TDF and BCT Taxonomy (v1) for developing an existing quality improvement intervention. The tools are compatible with the pragmatic P-D-S-A cycle approach generally used in quality improvement work.
Appendix
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Literature
1.
go back to reference Health Service Ombudsman for England. Time to act—severe sepsis: rapid diagnosis and treatment saves lives. London: Parliamentary and Health Service Ombusdman; 2013. Health Service Ombudsman for England. Time to act—severe sepsis: rapid diagnosis and treatment saves lives. London: Parliamentary and Health Service Ombusdman; 2013.
2.
go back to reference Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2012;41(2):580–637.CrossRef Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2012;41(2):580–637.CrossRef
3.
go back to reference Daniels R. Key recommendations for sepsis briefing Sutton Coldfield, UK. 2013. Daniels R. Key recommendations for sepsis briefing Sutton Coldfield, UK. 2013.
4.
go back to reference College of Emergency Medicine. CEM clinical audits 2011–2012: severe sepsis and septic shock. London; 2012 25 September 2012. Report No College of Emergency Medicine. CEM clinical audits 2011–2012: severe sepsis and septic shock. London; 2012 25 September 2012. Report No
5.
go back to reference Daniels R, Nutbeam T, McNamara G, Galvin C. The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study. Emerg Med J. 2011;28:507–12.CrossRefPubMed Daniels R, Nutbeam T, McNamara G, Galvin C. The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study. Emerg Med J. 2011;28:507–12.CrossRefPubMed
6.
go back to reference Cronshaw HL. Impact of the Surviving Sepsis Campaign on the recognition and management of severe sepsis in the emergency department: are we failing? Emerg Med J. 2011;28:670–5.CrossRefPubMed Cronshaw HL. Impact of the Surviving Sepsis Campaign on the recognition and management of severe sepsis in the emergency department: are we failing? Emerg Med J. 2011;28:670–5.CrossRefPubMed
7.
go back to reference NICE. How to put NICE guidance into practice. A guide to implementation for organisations. 2005. NICE. How to put NICE guidance into practice. A guide to implementation for organisations. 2005.
9.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:1655.CrossRef Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:1655.CrossRef
10.
go back to reference Michie S, Johnston M, Abraham C, Lawton R, Parker D, Walker A, et al. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Saf Health Care. 2005;14(1):26–33.PubMedCentralCrossRefPubMed Michie S, Johnston M, Abraham C, Lawton R, Parker D, Walker A, et al. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Saf Health Care. 2005;14(1):26–33.PubMedCentralCrossRefPubMed
11.
go back to reference ICEBeRG. Designing theoretically-informed implementation interventions. Implement Sci. 2006;1:4.CrossRef ICEBeRG. Designing theoretically-informed implementation interventions. Implement Sci. 2006;1:4.CrossRef
12.
go back to reference Davies P, Walker A, Grimshaw J. A systematic review of the use of theory in the design of guideline dissemination and implementation strategies and interpretation of the results of rigorous evaluations. Implement Sci. 2010;5:14.PubMedCentralCrossRefPubMed Davies P, Walker A, Grimshaw J. A systematic review of the use of theory in the design of guideline dissemination and implementation strategies and interpretation of the results of rigorous evaluations. Implement Sci. 2010;5:14.PubMedCentralCrossRefPubMed
13.
go back to reference Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, et al. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2010;3, CD005470.PubMed Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, et al. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2010;3, CD005470.PubMed
14.
go back to reference Datta J, Petticrew M. Challenges to evaluating complex interventions: a content analysis of published papers. BMC Pub Health. 2013;13:568.CrossRef Datta J, Petticrew M. Challenges to evaluating complex interventions: a content analysis of published papers. BMC Pub Health. 2013;13:568.CrossRef
15.
go back to reference Hoffman TC, Erueti C, Glasziou PP. Poor description of non-pharmacological interventions: analysis of consecutive sample of randomised trials. BMJ. 2013;347:f3755.CrossRef Hoffman TC, Erueti C, Glasziou PP. Poor description of non-pharmacological interventions: analysis of consecutive sample of randomised trials. BMJ. 2013;347:f3755.CrossRef
16.
go back to reference Steinmo S, Fuller C, Stone SP, Michie S. Characterising an implementation intervention in terms of behaviour change techniques and theory: the “Sepsis Six” clinical care bundle. Implement Sci. 2015;10:1.CrossRef Steinmo S, Fuller C, Stone SP, Michie S. Characterising an implementation intervention in terms of behaviour change techniques and theory: the “Sepsis Six” clinical care bundle. Implement Sci. 2015;10:1.CrossRef
17.
go back to reference Berwick DM. Developing and testing changes in delivery of care. Ann Intern Med. 1998;128(8):651–6.CrossRefPubMed Berwick DM. Developing and testing changes in delivery of care. Ann Intern Med. 1998;128(8):651–6.CrossRefPubMed
18.
go back to reference Deming WE. The new economics for industry, government, education. 2nd ed. Boston, MA: MIT Press; 1994. Deming WE. The new economics for industry, government, education. 2nd ed. Boston, MA: MIT Press; 1994.
19.
go back to reference Shojania KG, Grimshaw JM. Evidence-based quality improvement: the state of the science. Health Aff. 2005;24(1):138–50.CrossRef Shojania KG, Grimshaw JM. Evidence-based quality improvement: the state of the science. Health Aff. 2005;24(1):138–50.CrossRef
20.
go back to reference Taylor MJ, McNicholas C, Nicolay C, Darzi A, Bell D, Reed JE. Systematic review of the application of the plan-do-study-act method to improve quality in healthcare. BMJ Qual Saf. 2014;23:290–8.PubMedCentralCrossRefPubMed Taylor MJ, McNicholas C, Nicolay C, Darzi A, Bell D, Reed JE. Systematic review of the application of the plan-do-study-act method to improve quality in healthcare. BMJ Qual Saf. 2014;23:290–8.PubMedCentralCrossRefPubMed
21.
go back to reference Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37.PubMedCentralCrossRefPubMed Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37.PubMedCentralCrossRefPubMed
22.
go back to reference Michie S, Richardson M, Johnston M, Abraham C, Francis J, Hardeman W, et al. The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions. Ann Behav Med. 2013;46(1):81–95.CrossRefPubMed Michie S, Richardson M, Johnston M, Abraham C, Francis J, Hardeman W, et al. The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions. Ann Behav Med. 2013;46(1):81–95.CrossRefPubMed
23.
go back to reference Michie S, Atkins L, West R. The behaviour change wheel: a guide to designing interventions. London: Silverback; 2014. Michie S, Atkins L, West R. The behaviour change wheel: a guide to designing interventions. London: Silverback; 2014.
24.
go back to reference French SD, Green SE, O’Connor DA, McKenzie JE, Francis JJ, Michie S, et al. Developing theory-informed behaviour change interventions to implement evidence into practice: a systematic approach using the Theoretical Domains Framework. Implement Sci. 2012;7:38.PubMedCentralCrossRefPubMed French SD, Green SE, O’Connor DA, McKenzie JE, Francis JJ, Michie S, et al. Developing theory-informed behaviour change interventions to implement evidence into practice: a systematic approach using the Theoretical Domains Framework. Implement Sci. 2012;7:38.PubMedCentralCrossRefPubMed
25.
go back to reference Bussieres AE, Patey AM, Francis JJ, Sales AE, Jeremy GM, Team CPP. Identifying factors likely to influence compliance with diagnostic imaging guideline recommendations for spine disorders among chiropractors in North America: a focus group study using the Theoretical Domains Framework. Implement Sci. 2012;7:82.PubMedCentralCrossRefPubMed Bussieres AE, Patey AM, Francis JJ, Sales AE, Jeremy GM, Team CPP. Identifying factors likely to influence compliance with diagnostic imaging guideline recommendations for spine disorders among chiropractors in North America: a focus group study using the Theoretical Domains Framework. Implement Sci. 2012;7:82.PubMedCentralCrossRefPubMed
26.
go back to reference Curran JA, Brehaut J, Patey A, Osmond M, Stiell I, Grimshaw J, et al. Understanding the Canadian adult CT head rule trial: use of the theoretical domains framework for process evaluation. Implement Sci. 2013;8(1):25.PubMedCentralCrossRefPubMed Curran JA, Brehaut J, Patey A, Osmond M, Stiell I, Grimshaw J, et al. Understanding the Canadian adult CT head rule trial: use of the theoretical domains framework for process evaluation. Implement Sci. 2013;8(1):25.PubMedCentralCrossRefPubMed
27.
go back to reference Patey AM, Islam R, Francis JJ, Bryson GL, Grimshaw JM, Canada PPT. Anesthesiologists’ and surgeons’ perceptions about routine pre-operative testing in low-risk patients: application of the Theoretical Domains Framework (TDF) to identify factors that influence physicians’ decisions to order pre-operative tests. Implement Sci. 2012;7:52.PubMedCentralCrossRefPubMed Patey AM, Islam R, Francis JJ, Bryson GL, Grimshaw JM, Canada PPT. Anesthesiologists’ and surgeons’ perceptions about routine pre-operative testing in low-risk patients: application of the Theoretical Domains Framework (TDF) to identify factors that influence physicians’ decisions to order pre-operative tests. Implement Sci. 2012;7:52.PubMedCentralCrossRefPubMed
28.
go back to reference Francis J, Stockton C, Eccles M, Johnston M, Cuthbertson B, Grimshaw J, et al. Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians’ blood transfusion behaviour. Br J Health Psychol. 2009;14(4):625–46.CrossRefPubMed Francis J, Stockton C, Eccles M, Johnston M, Cuthbertson B, Grimshaw J, et al. Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians’ blood transfusion behaviour. Br J Health Psychol. 2009;14(4):625–46.CrossRefPubMed
29.
go back to reference Fuller C, Besser S, Savage J, McAteer J, Stone S, Michie S. Application of a theoretical framework for behavior change to hospital workers’ real-time explanations for noncompliance with hand hygiene guidelines. Am J Infect Control. 2014;42(2):106–10.CrossRefPubMed Fuller C, Besser S, Savage J, McAteer J, Stone S, Michie S. Application of a theoretical framework for behavior change to hospital workers’ real-time explanations for noncompliance with hand hygiene guidelines. Am J Infect Control. 2014;42(2):106–10.CrossRefPubMed
30.
go back to reference Fleming A, Bradley C, Cullinan S, Byrne S. Antibiotic prescribing in long-term care facilities: a qualitative, multidisciplinary investigation. BMJ Open. 2014;4:11.CrossRef Fleming A, Bradley C, Cullinan S, Byrne S. Antibiotic prescribing in long-term care facilities: a qualitative, multidisciplinary investigation. BMJ Open. 2014;4:11.CrossRef
31.
go back to reference Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, et al. Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol. Implement Sci. 2014;9:80.PubMedCentralCrossRefPubMed Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, et al. Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol. Implement Sci. 2014;9:80.PubMedCentralCrossRefPubMed
32.
go back to reference Reeves S, Kuper A, Hodges BD. Qualitative research methodologies: ethnography. BMJ. 2008;337. Reeves S, Kuper A, Hodges BD. Qualitative research methodologies: ethnography. BMJ. 2008;337.
33.
go back to reference Landis J, Koch G. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159.CrossRefPubMed Landis J, Koch G. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159.CrossRefPubMed
34.
go back to reference Michie S, Johnston M, Francis J, Hardeman W, Eccles M. From theory to intervention: mapping theoretically derived behavioural determinants to behaviour change techniques. Appl Psychol. 2008;57(4):660–80. Michie S, Johnston M, Francis J, Hardeman W, Eccles M. From theory to intervention: mapping theoretically derived behavioural determinants to behaviour change techniques. Appl Psychol. 2008;57(4):660–80.
35.
go back to reference Cane J, Richardson M, Johnston M, Lahda R, Michie S. From lists of behaviour change techniques (BCTs) to structured hierarchies: comparison of two methods of developing a hierarchy of BCTs. Br J Health Psychol. 2014. Cane J, Richardson M, Johnston M, Lahda R, Michie S. From lists of behaviour change techniques (BCTs) to structured hierarchies: comparison of two methods of developing a hierarchy of BCTs. Br J Health Psychol. 2014.
36.
go back to reference Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ. 2014;348:g1687.CrossRefPubMed Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ. 2014;348:g1687.CrossRefPubMed
37.
go back to reference Ivers N, Jamtvedt G, Flottorp S, Young JM, Odgaard-Jensen J, French SD, et al. Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev. 2012;6:Cd000259.PubMed Ivers N, Jamtvedt G, Flottorp S, Young JM, Odgaard-Jensen J, French SD, et al. Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev. 2012;6:Cd000259.PubMed
38.
go back to reference Dalton M, Ludden F, Johnson M. 1391: improving patient outcomes in cardiothoracic nursing: a service collaboration between the hospital at night and ITU outreach services. Euro J Cardio Nurs. 2007;6(1 suppl):S50.CrossRef Dalton M, Ludden F, Johnson M. 1391: improving patient outcomes in cardiothoracic nursing: a service collaboration between the hospital at night and ITU outreach services. Euro J Cardio Nurs. 2007;6(1 suppl):S50.CrossRef
39.
go back to reference Bosch-Capblanch X, Abba K, Prictor M, Garner P. Contracts between patients and healthcare practitioners for improving patients’ adherence to treatment, prevention and health promotion activities. Cochrane Database Syst Rev. 2007;2, CD004808.PubMed Bosch-Capblanch X, Abba K, Prictor M, Garner P. Contracts between patients and healthcare practitioners for improving patients’ adherence to treatment, prevention and health promotion activities. Cochrane Database Syst Rev. 2007;2, CD004808.PubMed
40.
go back to reference Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P. CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med. 2008;148(4):295–309.CrossRefPubMed Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P. CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med. 2008;148(4):295–309.CrossRefPubMed
41.
go back to reference Walshe K. Understanding what works—and why—in quality improvement: the need for theory-driven evaluation. Int J Qual Health Care. 2007;19(2):57–9.CrossRefPubMed Walshe K. Understanding what works—and why—in quality improvement: the need for theory-driven evaluation. Int J Qual Health Care. 2007;19(2):57–9.CrossRefPubMed
Metadata
Title
Bridging the gap between pragmatic intervention design and theory: using behavioural science tools to modify an existing quality improvement programme to implement “Sepsis Six”
Authors
Siri H. Steinmo
Susan Michie
Christopher Fuller
Sarah Stanley
Caitriona Stapleton
Sheldon P. Stone
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Implementation Science / Issue 1/2015
Electronic ISSN: 1748-5908
DOI
https://doi.org/10.1186/s13012-016-0376-8

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