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Head & Face Medicine
Published in: Head & Face Medicine 1/2015

Open Access 01-12-2015 | Research

Efficacy of platelet rich fibrin in the reduction of the pain and swelling after impacted third molar surgery: Randomized multicenter split-mouth clinical trial

Authors: Ozkan Ozgul, Fatma Senses, Nilay Er, Umut Tekin, Hakan Hıfzı Tuz, Alper Alkan, Ismail Doruk Kocyigit, Fethi Atil

Published in: Head & Face Medicine | Issue 1/2015

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Abstract

Background

Impacted third molar removal is a routine procedure in oral and maxillofacial surgery. Platelet-rich fibrin (PRF) is a second generation platelet concentration which is produced by simplified protocol. The aim of this study was to assess the effectiveness of PRF in the healing process by evaluating the changes in pain and swelling after third molar surgery.

Methods

Fifty-six patients (23 male, 33 female) who provide the inclusion criteria were selected to participate in this study. The evaluation of the facial swelling was performed by using a horizontal and vertical guide. The pain was evaluated in the postoperative period using a visual analog scale (VAS) of 100 mm.

Results

Horizontal and vertical measurements showed more swelling at the control side (without PRF) in 3th day postoperatively (p < 0.05). There were no statistically significant differences regarding pain among the groups.

Conclusion

As a conclusion, PRF seems to be effectiveness on postoperative horizontal swelling after third molar surgery. PRF could be used on a routine basis after third molar extraction surgery.
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Metadata
Title
Efficacy of platelet rich fibrin in the reduction of the pain and swelling after impacted third molar surgery: Randomized multicenter split-mouth clinical trial
Authors
Ozkan Ozgul
Fatma Senses
Nilay Er
Umut Tekin
Hakan Hıfzı Tuz
Alper Alkan
Ismail Doruk Kocyigit
Fethi Atil
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Head & Face Medicine / Issue 1/2015
Electronic ISSN: 1746-160X
DOI
https://doi.org/10.1186/s13005-015-0094-5

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