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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2019

Open Access 01-12-2019 | Rhabdomyosarcoma | Case Report

Primary epithelioid rhabdomyosarcoma of the stomach: a case report and review of literature

Authors: Yangkun Wang, Pei Guo, Zhishang Zhang, Runde Jiang, Zuguo Li

Published in: Diagnostic Pathology | Issue 1/2019

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Abstract

Background

Epithelioid rhabdomyosarcoma is a rare tumor that generally occurs in the bladder, the parotid gland, or the skin of the neck. We describe an unusual case of primary epithelioid rhabdomyosarcoma of the stomach and review the literature.

Case presentation

A 64-year-old woman presented with a lesion at the gastroesophageal junction. Histopathological examination showed irregularly sized round cells with low cytoplasmic content and eccentric nuclei. Mitotic figures were present. Fibrovascular septa and areas of necrosis were observed between tumor cells. Tumor cells were strongly positive for MyoD1, desmin, and myogenin, and weakly positive for actin, CD56, and PGP9.5. The ki-67 index was ≥90%.

Conclusions

Primary epithelioid rhabdomyosarcoma of the stomach is extremely rare. Better awareness of this entity is necessary for early diagnosis and treatment.
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Metadata
Title
Primary epithelioid rhabdomyosarcoma of the stomach: a case report and review of literature
Authors
Yangkun Wang
Pei Guo
Zhishang Zhang
Runde Jiang
Zuguo Li
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2019
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/s13000-019-0917-y

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