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Diagnostic Pathology

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Open Access 01-12-2018 | Case Report

Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review

Authors: Hongwei Guan, Lizhi Zhang, Qiuping Zhang, Wenjing Qi, Suling Xie, Jinping Hou, Huali Wang

Published in: Diagnostic Pathology | Issue 1/2018

Abstract

Background

Primary angiosarcoma of the kidney is a rare and aggressive malignant tumor presenting with a recognizable vascular differentiation. Its prognosis is fatal and the pathogenesis remains unclear. Renal angiomyolipoma is a relatively infrequent renal cortical neoplasm and is composed of variable proportions of adipose tissue, spindle cells, epithelioid smooth muscle cells and abnormal thick-walled blood vessels.

Case presentation

Here, we reported a case in which a 64-year-old woman presenting with the chief complaint of a progressively enlarged mass in the left abdomen. Abdominal computed tomography confirmed presence of a tumor measuring 18 cm × 11 cm in the left posterior renal fascia. Microscopic examination and immunohistochemical staining confirmed co-existence of angiomyolipoma and angiosarcoma. Furthermore, the two components interspersed with each other and there were transitional zones between them.

Conclusions

In this case, we described for the first time a primary renal angiosarcoma possibly arising in a pre-existing angiomyolipoma of the kidney.

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Title: Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review
Authors: Hongwei Guan
Lizhi Zhang
Qiuping Zhang
Wenjing Qi
Suling Xie
Jinping Hou
Huali Wang
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Diagnostic Pathology / Issue 1/2018
Electronic ISSN: 1746-1596
DOI: https://doi.org/10.1186/s13000-018-0730-z

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Springer Medicine

Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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