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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2017

Open Access 01-12-2017 | Case Report

Case report: a case of eruptive collagenoma occurring in esophagus and intestine

Authors: Ping Gao, Lili Jing, Hai Huang, Cuiping Zhang, Junmei Hao

Published in: Diagnostic Pathology | Issue 1/2017

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Abstract

Background

Eruptive collagenoma is a rare disease. All of the previously reported cases were located on the skin. Here we report such a case occurring in esophagus and intestine.

Case presentation

Our patient is a Chinese woman. Two years ago, hundreds of small nodules were identified in her esophagus and intestine. The lesions were characterized by thickened hyalinized collagen fibers and haphazard neoplastic stellate cells. The tumor cells showed generally positive for vimentin and negative for h-CALD, CD34, desmin, CD163, AE1/AE3, CK7 and CK20. The nodules were blue with Masson Trichrome stain. The clinicopathological, immunohistochemical and histochemical features of the tumor were consistent with eruptive collagenoma. The patient was not given specific treatment after diagnosis, and a routine examination indicated that there was no progress for 2 years.

Conclusion

Hitherto, this is the first case of eruptive collagenoma to have been reported occurring in esophagus and intestine.
Literature
1.
Cramer HJ. On the clinical aspects of the so-called “eruptive collagenoma”. Hautarzt. 1966;17:437–40.PubMed
2.
3.
Lee SH, Park SH, Song KY, Yoon TJ, Kim TH. Papular elastorrhexis in childhood improved by intralesional injections of triamcinolone. J Dermatol. 2001;28:569–71.CrossRefPubMed
4.
Betti R, Inselvini E, Pazzini C, Moneghini L, Crosti C. Symmetrical, papular, eruptive auricular collagenomas. J Am Acad Dermatol. 1998;39:363–4.CrossRefPubMed
5.
McClung AA, Blumberg MA, Huttenbach Y, Colome-Grimmer MI, Raimer SS. Development of collagenomas during pregnancy. J Am Acad Dermatol. 2005;53(Suppl):150–3.CrossRef
6.
Amaya M, Okubo Y, Koga M. A case of eruptive collagenoma localized on the neck and shoulders. J Dermatol. 2002;29:79–85.CrossRefPubMed
7.
8.
Xia Y, Darling TN. Darling, Rapidly growing collagenomas in multiple endocrine neoplasia type I. J Am Acad Dermatol. 2007;56:877–80.CrossRefPubMed
9.
Batra P, Loyd A, Patel R, Walters R, Stein JA. Eruptive collagenomas. Dermatol Online J. 2010;16:3.PubMed
10.
11.
de Almeida HL, Jr Breunig Jde A, Wolter M, de Castro LA, Rocha NM. Light and electron microscopy of eruptive collagenoma. J Cutan Pathol. 2009;36:35–8.CrossRefPubMed
12.
Zhao C, Ma W, Wang Y, Sun Q. Female with eruptive collagenoma clustered in the left lateral aspect of the abdomen. J Dermatol. 2010;37:843–5.CrossRefPubMed
13.
Kim HR, Na CH, Shin BS, Choi KC, Kim MS. A case of eruptive collagenoma. Korean J Dermatol. 2012;50:539–43.
14.
Xiao M, Yang L, Dong L, Wang Y, Sun X, Tao J. Three cases of eruptive collagenoma and a literature review, 1970-2012. Eur J Dermatol. 2014;24:384–5.PubMed
15.
Pierarad GE, Lapiere CM. Nevi of connective tissue. A reappraisal of their classification. Am J Dermatopathol. 1985;7:325–33.CrossRef
16.
Ryder HF, Antaya RJ. Nevus anelasticus, papular elastorrhexis, and eruptive collagenoma. clinically similar entities with focal absence of elastic fibers in childhood. Pediatr Dermatol. 2005;22:153–7.CrossRefPubMed
17.
Bordas X, Ferrandiz C, Ribera M, Galofre E. Papular elastorrhexis: a variety of nevus anelasticus? Arch Dermatol. 1987;123:433–4.CrossRefPubMed
18.
Ramos D, Monteagudo C, Carda C, Ramo’n D, Gonza’lez-Devesa M, Llombart-Bosch A. Ultrastructural and immunohistochemical characterization of the so-called giant multinucleate cells in cutaneous collagenomas. Histopathology. 2002;41:134–43.CrossRefPubMed
19.
Lee SH, Sung NH. The importance of collagen tissue in papular elastorrhexis, eruptive collagenoma, and nevus anelasticus. Ann Dermatol. 2016;28:210–5.CrossRefPubMedPubMedCentral
20.
Ju Q, Song N, Sun J. Eruptive cutaneous collagenoma in a Chinese patient. J Dermatol. 2011;38:399–401.CrossRefPubMed
21.
Uitto J, Bauer EA, Santa Cruz DJ, Holtmann B, Eisen AZ. Decreased collagenase production by regional fibroblasts cultured from skin of a patient with connective tissue nevi of the collagen type. J Invest Dermatol. 1982;78:136–40.CrossRefPubMed
22.
Uitto J, Santa Cruz DJ, Eisen AZ. Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type. J Am Acad Dermatol. 1980;3:441–61.CrossRefPubMed
Metadata
Title
Case report: a case of eruptive collagenoma occurring in esophagus and intestine
Authors
Ping Gao
Lili Jing
Hai Huang
Cuiping Zhang
Junmei Hao
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2017
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/s13000-017-0617-4

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