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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2016

Open Access 01-12-2016 | Research

Benign intestinal glandular lesions in the vagina: a possible correlation with implantation

Authors: Weiwei Lu, Xiaofei Zhang, Bingjian Lu

Published in: Diagnostic Pathology | Issue 1/2016

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Abstract

Background

Enteric-type glandular lesions are extremely rare in the vagina. Their histological origin remains a matter of speculation at present.

Method

We review two rectal mucosal prolapse-like polyps and one intestinal-type adenosis in the vagina.

Results

Case 1, a 64-year-old woman, presented with a vaginal polypoid lesion with a size of 4 × 3 × 3 cm. Case 2, an 8-year-old girl, had a 1.5 × 1.5 × 0.8-cm pedunculated polyp in the vaginal navicular fossa and a clinically suspected rectovaginal fistula. Case 1 and 3 had an obsolete severe perineal laceration. On histopathological examination, cases 1 and 2 resembled rectal mucosal prolapse or inflammatory cloacogenic polyp (rectal mucosal prolapse-like polyp). Case 3 had an incidental intestinal-type adenosis in the removed vaginal wall. Immunohistochemistry confirmed the intestinal differentiation in all 3 lesions by showing diffuse CDX2-positive, CK20-positive, and scattered chromogranin A-positive neuroendocrinal cells in the lower compartment of the crypt.

Conclusions

In summary, we report herein three unusual cases of benign intestinal-type glandular lesions in the vagina including two rectal mucosal prolapse-like polyps and one case of intestinal-type adenosis, and discuss possibilities for their histogenetic basis.
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Metadata
Title
Benign intestinal glandular lesions in the vagina: a possible correlation with implantation
Authors
Weiwei Lu
Xiaofei Zhang
Bingjian Lu
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2016
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/s13000-016-0503-5

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