Skip to main content
Top
Published in: Chiropractic & Manual Therapies 1/2020

01-12-2020 | Back Pain | Study protocol

The prognostic merit of self-reported triggers of recurrent low back pain: study protocol

Authors: Emad M. Ardakani, Charlotte Leboeuf-Yde, Angela Jacques, Bruce F. Walker

Published in: Chiropractic & Manual Therapies | Issue 1/2020

Login to get access

Abstract

Background

Most cases of low back pain (LBP) are regarded as non-specific and current studies indicate that for many this is a chronic recurrent condition, in which people experience episodes of pain with symptom-free periods in between. It is likely that acute exposure to some factors triggers the reappearance of new episodes in recurrent LBP regardless of the causality of the underlying condition (i.e. risk factors). Additionally, it has been shown that LBP patients present with different trajectories and different trajectories possibly have different triggers. Hence, dividing patients into some clinically meaningful subgroups may offer new insights into triggers, effective preventive strategies and, therefore, prognosis. This study aims to identify self-reported triggers and trajectories of episodes of recurrent LBP and to examine the prognostic association between different triggers and LBP trajectories.

Methods

This is a longitudinal, multicentre, Australia-wide observational study of patients with recurrent non-specific LBP. Two hundred adults with at least a one-year history of LBP will be recruited from primary care clinics or private practices and followed for a year. Each will receive an SMS every fortnight (26 time-points in total) enquiring the occurrence of a new episode of pain in the past 2 weeks and its intensity. Upon report of a new episode, a telephone interview will be performed to appraise exposure to self-nominated triggers in a period of 24 h preceding the pain. Trajectories will be identified by latent class analysis at the end of the follow-up based on the pain intensity, frequency, and length of episodes. Triggers will be categorised into physical and psychosocial groups. Generalised linear mixed models with logit links will be used to explore pain triggers associated with pain trajectories.

Discussion

The completion of this study will provide insight into the patients’ self-reported triggers of LBP and also their possible prognostic association with different trajectories. Some newly-identified and pre-identified triggers are likely to be found and reported.
Literature
1.
2.
go back to reference Hoy D, et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64(6):2028–37.CrossRefPubMed Hoy D, et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64(6):2028–37.CrossRefPubMed
3.
4.
go back to reference WHO. The burden of musculoskeletal conditions at the start of the new millennium. World Health Organ Tech Rep Ser. 2003;919:i-x, 1–218 back cover. WHO. The burden of musculoskeletal conditions at the start of the new millennium. World Health Organ Tech Rep Ser. 2003;919:i-x, 1–218 back cover.
5.
go back to reference Walker BF, Muller R, Grant WD. Low Back pain in Australian adults. Prevalence and associated disability. J Manip Physiol Ther. 2004;27(4):238–44.CrossRef Walker BF, Muller R, Grant WD. Low Back pain in Australian adults. Prevalence and associated disability. J Manip Physiol Ther. 2004;27(4):238–44.CrossRef
6.
go back to reference Walker BF. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord. 2000;13(3):205–17.CrossRefPubMed Walker BF. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord. 2000;13(3):205–17.CrossRefPubMed
7.
go back to reference Kyu HH, et al. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018;392(10159):1859–922.CrossRef Kyu HH, et al. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018;392(10159):1859–922.CrossRef
8.
go back to reference Gore M, et al. The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings. Spine (Phila Pa 1976). 2012;37(11):E668–77.CrossRef Gore M, et al. The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings. Spine (Phila Pa 1976). 2012;37(11):E668–77.CrossRef
9.
go back to reference Maetzel A, Li L. The economic burden of low back pain: a review of studies published between 1996 and 2001. Best Pract Res Clin Rheumatol. 2002;16(1):23–30.CrossRefPubMed Maetzel A, Li L. The economic burden of low back pain: a review of studies published between 1996 and 2001. Best Pract Res Clin Rheumatol. 2002;16(1):23–30.CrossRefPubMed
10.
go back to reference Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J. 2008;8(1):8–20.CrossRefPubMed Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J. 2008;8(1):8–20.CrossRefPubMed
12.
go back to reference Foster NE, et al. Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet. 2018;391(10137):2368–83.CrossRefPubMed Foster NE, et al. Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet. 2018;391(10137):2368–83.CrossRefPubMed
13.
14.
go back to reference Nachemson A, Bigos SJ. The low back. In: JRW C, editor. Adult Orthopedics; 1984. p. 843–937. Nachemson A, Bigos SJ. The low back. In: JRW C, editor. Adult Orthopedics; 1984. p. 843–937.
15.
go back to reference Leboeuf-Yde C, et al. Evidence-based classification of low back pain in the general population: one-year data collected with SMS track. Chiropr Man Therap. 2013;21:30.CrossRefPubMedPubMedCentral Leboeuf-Yde C, et al. Evidence-based classification of low back pain in the general population: one-year data collected with SMS track. Chiropr Man Therap. 2013;21:30.CrossRefPubMedPubMedCentral
16.
go back to reference Von Korff M, Saunders K. The course of back pain in primary care. Spine (Phila Pa 1976). 1996;21(24):2833–7 discussion 2838-9.CrossRef Von Korff M, Saunders K. The course of back pain in primary care. Spine (Phila Pa 1976). 1996;21(24):2833–7 discussion 2838-9.CrossRef
17.
go back to reference Ailliet L, et al. Long-term trajectories of patients with neck pain and low back pain presenting to chiropractic care: a latent class growth analysis. Eur J Pain. 2018;22(1):103–13.CrossRefPubMed Ailliet L, et al. Long-term trajectories of patients with neck pain and low back pain presenting to chiropractic care: a latent class growth analysis. Eur J Pain. 2018;22(1):103–13.CrossRefPubMed
18.
19.
20.
go back to reference Leboeuf-Yde C, et al. The Nordic Back pain subpopulation program: a 1-year prospective multicenter study of outcomes of persistent low-Back pain in chiropractic patients. J Manip Physiol Ther. 2005;28(2):90–6.CrossRef Leboeuf-Yde C, et al. The Nordic Back pain subpopulation program: a 1-year prospective multicenter study of outcomes of persistent low-Back pain in chiropractic patients. J Manip Physiol Ther. 2005;28(2):90–6.CrossRef
21.
go back to reference Dunn KM, Hestbaek L, Cassidy JD. Low back pain across the life course. Best Pract Res Clin Rheumatol. 2013;27(5):591–600.CrossRefPubMed Dunn KM, Hestbaek L, Cassidy JD. Low back pain across the life course. Best Pract Res Clin Rheumatol. 2013;27(5):591–600.CrossRefPubMed
22.
go back to reference Cassidy JD, et al. Incidence and course of low Back pain episodes in the general population. Spine. 2005;30(24):2817–23.CrossRefPubMed Cassidy JD, et al. Incidence and course of low Back pain episodes in the general population. Spine. 2005;30(24):2817–23.CrossRefPubMed
23.
go back to reference Henschke N, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. Bmj. 2008;337:a171.CrossRefPubMed Henschke N, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. Bmj. 2008;337:a171.CrossRefPubMed
24.
go back to reference Stanton TR, et al. After an episode of acute low Back pain, recurrence is unpredictable and not as common as previously thought. Spine. 2008;33(26):2923–8.CrossRefPubMed Stanton TR, et al. After an episode of acute low Back pain, recurrence is unpredictable and not as common as previously thought. Spine. 2008;33(26):2923–8.CrossRefPubMed
25.
go back to reference Ardakani EM, Leboeuf-Yde C, Walker BF. Failure to define low back pain as a disease or an episode renders research on causality unsuitable: results of a systematic review. Chiropractic Manual Ther. 2018;26(1):1.CrossRef Ardakani EM, Leboeuf-Yde C, Walker BF. Failure to define low back pain as a disease or an episode renders research on causality unsuitable: results of a systematic review. Chiropractic Manual Ther. 2018;26(1):1.CrossRef
26.
go back to reference Ardakani EM, Leboeuf-Yde C, Walker BF. Can we trust the literature on risk factors and triggers for low Back pain? A Systematic Review of a Sample of Contemporary Literature. Pain Res Manag. 2019;2019:13.CrossRef Ardakani EM, Leboeuf-Yde C, Walker BF. Can we trust the literature on risk factors and triggers for low Back pain? A Systematic Review of a Sample of Contemporary Literature. Pain Res Manag. 2019;2019:13.CrossRef
27.
go back to reference de Vet HC, et al. Episodes of low back pain: a proposal for uniform definitions to be used in research. Spine (Phila Pa 1976). 2002;27(21):2409–16.CrossRef de Vet HC, et al. Episodes of low back pain: a proposal for uniform definitions to be used in research. Spine (Phila Pa 1976). 2002;27(21):2409–16.CrossRef
28.
go back to reference Stanton TR, et al. How do we define the condition 'recurrent low back pain'? A systematic review. Eur Spine J. 2010;19(4):533–9.CrossRefPubMed Stanton TR, et al. How do we define the condition 'recurrent low back pain'? A systematic review. Eur Spine J. 2010;19(4):533–9.CrossRefPubMed
29.
go back to reference Leboeuf-Yde C, et al. Absence of low back pain in the general population followed fortnightly over one year with automated text messages. Chiropr Man Therap. 2014;22(1):1.CrossRefPubMedPubMedCentral Leboeuf-Yde C, et al. Absence of low back pain in the general population followed fortnightly over one year with automated text messages. Chiropr Man Therap. 2014;22(1):1.CrossRefPubMedPubMedCentral
30.
go back to reference Eklund A, et al. Absence of low back pain to demarcate an episode: a prospective multicentre study in primary care. Chiropr Man Ther. 2016;24(1):3.CrossRef Eklund A, et al. Absence of low back pain to demarcate an episode: a prospective multicentre study in primary care. Chiropr Man Ther. 2016;24(1):3.CrossRef
31.
go back to reference Axen I, Leboeuf-Yde C. Trajectories of low back pain. Best Pract Res Clin Rheumatol. 2013;27(5):601–12.CrossRefPubMed Axen I, Leboeuf-Yde C. Trajectories of low back pain. Best Pract Res Clin Rheumatol. 2013;27(5):601–12.CrossRefPubMed
32.
go back to reference Dunn KM, Jordan K, Croft PR. Characterizing the course of low back pain: a latent class analysis. Am J Epidemiol. 2006;163(8):754–61.CrossRefPubMed Dunn KM, Jordan K, Croft PR. Characterizing the course of low back pain: a latent class analysis. Am J Epidemiol. 2006;163(8):754–61.CrossRefPubMed
33.
go back to reference Tamcan O, et al. The course of chronic and recurrent low back pain in the general population. PAIN. 2010;150(3):451–7.CrossRefPubMed Tamcan O, et al. The course of chronic and recurrent low back pain in the general population. PAIN. 2010;150(3):451–7.CrossRefPubMed
34.
go back to reference Axen I, et al. Clustering patients on the basis of their individual course of low back pain over a six month period. BMC Musculoskelet Disord. 2011;12(1):99.CrossRefPubMedPubMedCentral Axen I, et al. Clustering patients on the basis of their individual course of low back pain over a six month period. BMC Musculoskelet Disord. 2011;12(1):99.CrossRefPubMedPubMedCentral
35.
36.
go back to reference Steffens D, et al. Clinicians' views on factors that trigger a sudden onset of low back pain. Eur Spine J. 2014;23(3):512–9.CrossRefPubMed Steffens D, et al. Clinicians' views on factors that trigger a sudden onset of low back pain. Eur Spine J. 2014;23(3):512–9.CrossRefPubMed
37.
go back to reference Steffens D, et al. What triggers an episode of acute low back pain? Arthritis Care Res (Hoboken): A case-crossover study; 2015. Steffens D, et al. What triggers an episode of acute low back pain? Arthritis Care Res (Hoboken): A case-crossover study; 2015.
38.
go back to reference Parreira Pdo C, et al. Can patients identify what triggers their back pain? Secondary analysis of a case-crossover study. Pain. 2015;156(10):1913–9.CrossRef Parreira Pdo C, et al. Can patients identify what triggers their back pain? Secondary analysis of a case-crossover study. Pain. 2015;156(10):1913–9.CrossRef
39.
go back to reference Stevens ML, et al. Patients' and Physiotherapists' views on triggers for low Back pain. Spine (Phila Pa 1976). 2016;41(4):E218–24.CrossRef Stevens ML, et al. Patients' and Physiotherapists' views on triggers for low Back pain. Spine (Phila Pa 1976). 2016;41(4):E218–24.CrossRef
40.
go back to reference Dunn KM, Campbell P, Jordan KP. Validity of the visual trajectories questionnaire for pain. J Pain. 2017. Dunn KM, Campbell P, Jordan KP. Validity of the visual trajectories questionnaire for pain. J Pain. 2017.
42.
go back to reference Pettersson A, et al. Which instruments to support diagnosis of depression have sufficient accuracy? A systematic review. Nord J Psychiatry. 2015;69(7):497–508.CrossRefPubMed Pettersson A, et al. Which instruments to support diagnosis of depression have sufficient accuracy? A systematic review. Nord J Psychiatry. 2015;69(7):497–508.CrossRefPubMed
43.
go back to reference Choi Y, et al. What is the best screening test for depression in chronic spinal pain patients? Spine J. 2014;14(7):1175–82.CrossRefPubMed Choi Y, et al. What is the best screening test for depression in chronic spinal pain patients? Spine J. 2014;14(7):1175–82.CrossRefPubMed
44.
go back to reference Spitzer RL, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–7.CrossRefPubMed Spitzer RL, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–7.CrossRefPubMed
45.
go back to reference Lowe B, et al. Validation and standardization of the generalized anxiety disorder screener (GAD-7) in the general population. Med Care. 2008;46(3):266–74.CrossRefPubMed Lowe B, et al. Validation and standardization of the generalized anxiety disorder screener (GAD-7) in the general population. Med Care. 2008;46(3):266–74.CrossRefPubMed
46.
go back to reference Jensen MP, et al. The subjective experience of acute pain. An assessment of the utility of 10 indices. Clin J Pain. 1989;5(2):153–9.CrossRefPubMed Jensen MP, et al. The subjective experience of acute pain. An assessment of the utility of 10 indices. Clin J Pain. 1989;5(2):153–9.CrossRefPubMed
47.
go back to reference Price DD, et al. A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scales. Pain. 1994;56(2):217–26.CrossRefPubMed Price DD, et al. A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scales. Pain. 1994;56(2):217–26.CrossRefPubMed
48.
go back to reference Ferreira-Valente MA, Pais-Ribeiro JL, Jensen MP. Validity of four pain intensity rating scales. PAIN. 2011;152(10):2399–404.CrossRefPubMed Ferreira-Valente MA, Pais-Ribeiro JL, Jensen MP. Validity of four pain intensity rating scales. PAIN. 2011;152(10):2399–404.CrossRefPubMed
49.
go back to reference Dziak JJ, Lanza ST, Tan X. Effect size, statistical power and sample size requirements for the bootstrap likelihood ratio test in latent class Analysis. Struct Equ Model. 2014;21(4):534–52.CrossRef Dziak JJ, Lanza ST, Tan X. Effect size, statistical power and sample size requirements for the bootstrap likelihood ratio test in latent class Analysis. Struct Equ Model. 2014;21(4):534–52.CrossRef
50.
go back to reference Analysis ALC. Cambridge: Cambridge University press; 2002. Analysis ALC. Cambridge: Cambridge University press; 2002.
52.
go back to reference Lanza ST, Savage JS, Birch LL. Identification and prediction of latent classes of weight-loss strategies among women. Obesity (Silver Spring). 2010;18(4):833–40.CrossRef Lanza ST, Savage JS, Birch LL. Identification and prediction of latent classes of weight-loss strategies among women. Obesity (Silver Spring). 2010;18(4):833–40.CrossRef
53.
go back to reference Lanza S, Bray B. Transitions in drug use among high-risk women: an application of latent class and latent transition analysis. Adv Appl Stat Sci. 2010;3:203–35.PubMedPubMedCentral Lanza S, Bray B. Transitions in drug use among high-risk women: an application of latent class and latent transition analysis. Adv Appl Stat Sci. 2010;3:203–35.PubMedPubMedCentral
Metadata
Title
The prognostic merit of self-reported triggers of recurrent low back pain: study protocol
Authors
Emad M. Ardakani
Charlotte Leboeuf-Yde
Angela Jacques
Bruce F. Walker
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Chiropractic & Manual Therapies / Issue 1/2020
Electronic ISSN: 2045-709X
DOI
https://doi.org/10.1186/s12998-019-0291-6

Other articles of this Issue 1/2020

Chiropractic & Manual Therapies 1/2020 Go to the issue