Skip to main content
Top
Published in: Journal of Occupational Medicine and Toxicology 1/2017

Open Access 01-12-2017 | Research

The effect of effort-reward imbalance on the health of childcare workers in Hamburg: a longitudinal study

Authors: Peter Koch, Jan Felix Kersten, Johanna Stranzinger, Albert Nienhaus

Published in: Journal of Occupational Medicine and Toxicology | Issue 1/2017

Login to get access

Abstract

Background

The prevalence of effort-reward imbalance (ERI) among qualified childcare workers in Germany is currently estimated at around 65%. High rates of burnout and musculoskeletal symptoms (MS) have also been reported for this group. Previous longitudinal studies show inconsistent results with regard to the association between ERI and MS. As yet, no longitudinal studies have been conducted to investigate the association between ERI and burnout or MS in childcare workers. This study aims to investigate the extent to which a relationship between ERI and MS or burnout can be observed in childcare workers in Germany on a longitudinal basis.

Methods

In 2014 childcare workers (N = 199, response rate: 57%) of a provider of facilities for children and youth in Hamburg were asked about stress and health effects in the workplace. Follow-up was completed one year later (N = 106, follow-up rate: 53%) For the baseline assessment, ERI was determined as the primary influencing factor. Data on MS was recorded using the Nordic questionnaire, and burnout using the personal burnout scale of the Copenhagen Burnout Inventory (CBI). The statistical analysis was carried out using multivariate linear and logistic regression.

Results

At baseline ERI was present in 65% of the sample population. The mean burnout score at the time of follow-up was 53.7 (SD: 20.7); the prevalence of MS was between 19% and 62%. ERI was identified as a statistically significant factor for MS, after adjusting especially for physical stress (lower back: OR 4.2; 95% CI: 1.14 to 15.50, neck: OR 4.3; 95% CI: 1.25 to 15.0, total MS: OR 4.0; 95% CI: 1.20 to 13.49). With regard to burnout, a relative increase of 10% in the ERI ratio score increased the burnout score by 1.1 points (p = 0.034).

Conclusions

ERI was revealed to be a major factor in relation to MS and burnout in childcare workers. Based on this observation worksite interventions on the individual and organizational level should be introduced in order to prevent ERI.
Appendix
Available only for authorised users
Literature
1.
go back to reference Siegrist J. Adverse health effects of high-effort/low-reward conditions. J Occup Health Psychol. 1996;1:27–41.CrossRefPubMed Siegrist J. Adverse health effects of high-effort/low-reward conditions. J Occup Health Psychol. 1996;1:27–41.CrossRefPubMed
2.
go back to reference Koch P, Stranzinger J, Nienhaus A, Kozak A. Musculoskeletal Symptoms and Risk of Burnout in Child Care Workers - A Cross-Sectional Study. PLoS One. 2015;10:e0140980.CrossRefPubMedPubMedCentral Koch P, Stranzinger J, Nienhaus A, Kozak A. Musculoskeletal Symptoms and Risk of Burnout in Child Care Workers - A Cross-Sectional Study. PLoS One. 2015;10:e0140980.CrossRefPubMedPubMedCentral
3.
go back to reference Schreyer I, Krause M, Brandl M, Nicko O. AQUA Arbeitsplatz und Qualität in Kitas Ergebnisse einer bundesweiten Befragung. München: Staatsinstitut für Frühpädagogik; 2014. Schreyer I, Krause M, Brandl M, Nicko O. AQUA Arbeitsplatz und Qualität in Kitas Ergebnisse einer bundesweiten Befragung. München: Staatsinstitut für Frühpädagogik; 2014.
5.
go back to reference Siegrist J, Dragano N. Psychosoziale Belastungen und Erkrankungsrisiken im Erwerbsleben. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz. 2008;51(3):305–12.CrossRefPubMed Siegrist J, Dragano N. Psychosoziale Belastungen und Erkrankungsrisiken im Erwerbsleben. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz. 2008;51(3):305–12.CrossRefPubMed
6.
go back to reference von Kanel R, Bellingrath S, Kudielka BM. Overcommitment but not effort-reward imbalance relates to stress-induced coagulation changes in teachers. Ann Behav Med. 2009;37(1):20–8.CrossRef von Kanel R, Bellingrath S, Kudielka BM. Overcommitment but not effort-reward imbalance relates to stress-induced coagulation changes in teachers. Ann Behav Med. 2009;37(1):20–8.CrossRef
7.
go back to reference Bellingrath S, Rohleder N, Kudielka BM. Healthy working school teachers with high effort–reward-imbalance and overcommitment show increased pro-inflammatory immune activity and a dampened innate immune defence. Brain Behav Immun. 2010;24(8):1332–9.CrossRefPubMed Bellingrath S, Rohleder N, Kudielka BM. Healthy working school teachers with high effort–reward-imbalance and overcommitment show increased pro-inflammatory immune activity and a dampened innate immune defence. Brain Behav Immun. 2010;24(8):1332–9.CrossRefPubMed
8.
go back to reference Jolivet A, Caroly S, Ehlinger V, Kelly-Irving M, Delpierre C, Balducci F, et al. Linking hospital workers' organisational work environment to depressive symptoms: A mediating effect of effort-reward imbalance? The ORSOSA study. Soc Sci Med. 2010;71(3):534–40.CrossRefPubMed Jolivet A, Caroly S, Ehlinger V, Kelly-Irving M, Delpierre C, Balducci F, et al. Linking hospital workers' organisational work environment to depressive symptoms: A mediating effect of effort-reward imbalance? The ORSOSA study. Soc Sci Med. 2010;71(3):534–40.CrossRefPubMed
9.
go back to reference Weyers S, Peter R, Boggild H, Jeppesen HJ, Siegrist J. Psychosocial work stress is associated with poor self-rated health in Danish nurses: a test of the effort-reward imbalance model. Scand J Caring Sci. 2006;20:26–34.CrossRefPubMed Weyers S, Peter R, Boggild H, Jeppesen HJ, Siegrist J. Psychosocial work stress is associated with poor self-rated health in Danish nurses: a test of the effort-reward imbalance model. Scand J Caring Sci. 2006;20:26–34.CrossRefPubMed
10.
go back to reference Buch M, Frieling E. Belastungs- und Beanspruchungsoptimierung in Kindertagestätten. Kassel: Eigenverlag Universität Kassel, Institut für Arbeitswissenschaft; 2001. Buch M, Frieling E. Belastungs- und Beanspruchungsoptimierung in Kindertagestätten. Kassel: Eigenverlag Universität Kassel, Institut für Arbeitswissenschaft; 2001.
11.
go back to reference Grant KA, Habes DJ, Tepper AL. Work activities and musculoskeletal complaints among preschool workers. Appl Ergon. 1995;26:405–10.CrossRefPubMed Grant KA, Habes DJ, Tepper AL. Work activities and musculoskeletal complaints among preschool workers. Appl Ergon. 1995;26:405–10.CrossRefPubMed
12.
go back to reference Botzet M, Frank H. Arbeit und Gesundheit von Mitarbeiterinnen in Kindertageseinrichtungen. Regionalfallstudie in saarländischen Kindertageseinrichtungen. Landesarbeitsgemeinschaft für Gesundheitsförderung Saarland e.V: Saarbrücken; 1998. Botzet M, Frank H. Arbeit und Gesundheit von Mitarbeiterinnen in Kindertageseinrichtungen. Regionalfallstudie in saarländischen Kindertageseinrichtungen. Landesarbeitsgemeinschaft für Gesundheitsförderung Saarland e.V: Saarbrücken; 1998.
13.
go back to reference Gratz RR, Claffey A. Adult health in childcare: health status, behaviors, and concerns of teachers, directots, and family child care providers. Early Child Res Q. 1996;11:243–67.CrossRef Gratz RR, Claffey A. Adult health in childcare: health status, behaviors, and concerns of teachers, directots, and family child care providers. Early Child Res Q. 1996;11:243–67.CrossRef
14.
go back to reference Rugulies R, Krause N. Effort-reward imbalance and incidence of low back and neck injuries in San Francisco transit operators. Occup Environ Med. 2008;65:525–33.CrossRefPubMed Rugulies R, Krause N. Effort-reward imbalance and incidence of low back and neck injuries in San Francisco transit operators. Occup Environ Med. 2008;65:525–33.CrossRefPubMed
15.
go back to reference Lapointe J, Dionne CE, Brisson C, Montreuil S. Effort-reward imbalance and video display unit postural risk factors interact in women on the incidence of musculoskeletal symptoms. Work. 2013;44:133–43.PubMed Lapointe J, Dionne CE, Brisson C, Montreuil S. Effort-reward imbalance and video display unit postural risk factors interact in women on the incidence of musculoskeletal symptoms. Work. 2013;44:133–43.PubMed
16.
go back to reference Krause N, Burgel B, Rempel D. Effort-reward imbalance and one-year change in neck-shoulder and upper extremity pain among call center computer operators. Scand J Work Environ Health. 2010;36:42–53.CrossRefPubMed Krause N, Burgel B, Rempel D. Effort-reward imbalance and one-year change in neck-shoulder and upper extremity pain among call center computer operators. Scand J Work Environ Health. 2010;36:42–53.CrossRefPubMed
17.
18.
go back to reference Schaufeli WB, Buunk BP. Burnout. An overview of 25 years of research and theorizing. In: Schabracq MJ, Winnubst JA, Cooper CL, editors. The handbook of work and health psychology. 2nd edn edition. New York: Wiley & Sons; 2003. p. 383–425. Schaufeli WB, Buunk BP. Burnout. An overview of 25 years of research and theorizing. In: Schabracq MJ, Winnubst JA, Cooper CL, editors. The handbook of work and health psychology. 2nd edn edition. New York: Wiley & Sons; 2003. p. 383–425.
19.
go back to reference Manlove EE. Multiple correlates of burnout in child care workers. Early Child Res Q. 1993;8:499–518.CrossRef Manlove EE. Multiple correlates of burnout in child care workers. Early Child Res Q. 1993;8:499–518.CrossRef
20.
go back to reference Kushnir T, Milbauer V. Managing stress and burnout at work. A cognitive group intervention. Program for directors of day care centers. Pediatrics. 1994;94:1074–7.PubMed Kushnir T, Milbauer V. Managing stress and burnout at work. A cognitive group intervention. Program for directors of day care centers. Pediatrics. 1994;94:1074–7.PubMed
21.
go back to reference Whitebook M, Howes C, Darrah R, Friedman J. Who's minding the child care workers? A look at staff burnout. Child Today. 1980;10:2–6. Whitebook M, Howes C, Darrah R, Friedman J. Who's minding the child care workers? A look at staff burnout. Child Today. 1980;10:2–6.
22.
go back to reference Bertolino B, Thompson K. The residential youth care worker in action. Binghamton, New York: Hawthorn Press; 1999. Bertolino B, Thompson K. The residential youth care worker in action. Binghamton, New York: Hawthorn Press; 1999.
23.
go back to reference Snow K. Aggression: Just part of the job? The psychological impact of aggression on child and youth workers. J Child Youth Care. 1994;9:11–30. Snow K. Aggression: Just part of the job? The psychological impact of aggression on child and youth workers. J Child Youth Care. 1994;9:11–30.
24.
go back to reference Rudow B. Belastungen im Erzieher/innenberuf. Bildung Wissenschaft. 2004;6:6–11. Rudow B. Belastungen im Erzieher/innenberuf. Bildung Wissenschaft. 2004;6:6–11.
25.
go back to reference Jungbauer J, Ehlen S. Stress and Burnout Risk in Nursery School Teachers: Results from a Survey. Gesundheitswesen. 2015;77:418–23.PubMed Jungbauer J, Ehlen S. Stress and Burnout Risk in Nursery School Teachers: Results from a Survey. Gesundheitswesen. 2015;77:418–23.PubMed
26.
go back to reference Scheuch K, Seibt R. Arbeits- und persönlichkeitsbedingte Beziehungen zu Burnout - eine kritische Betrachtung. In: Richter PG, Rau R, Mühlpfordt S, editors. Arbeit und Gesundheit. Lengerich: Pabst Science Publishers; 2007. p. 42–54. Scheuch K, Seibt R. Arbeits- und persönlichkeitsbedingte Beziehungen zu Burnout - eine kritische Betrachtung. In: Richter PG, Rau R, Mühlpfordt S, editors. Arbeit und Gesundheit. Lengerich: Pabst Science Publishers; 2007. p. 42–54.
27.
go back to reference Nübling M, Seidler A, Garthus-Niegel S, Latza U, Wagner M, Hegewald J, et al. The Gutenberg Health Study: measuring psychosocial factors at work and predicting health and work-related outcomes with the ERI and the COPSOQ questionnaire. BMC Public Health. 2013;13:538.CrossRef Nübling M, Seidler A, Garthus-Niegel S, Latza U, Wagner M, Hegewald J, et al. The Gutenberg Health Study: measuring psychosocial factors at work and predicting health and work-related outcomes with the ERI and the COPSOQ questionnaire. BMC Public Health. 2013;13:538.CrossRef
28.
go back to reference Koch P, Stranzinger J, Kersten JF, Nienhaus A. Use of moulded hearing protectors by child care workers - an interventional pilot study. J Occup Med Toxicol. 2016;11:50.CrossRefPubMedPubMedCentral Koch P, Stranzinger J, Kersten JF, Nienhaus A. Use of moulded hearing protectors by child care workers - an interventional pilot study. J Occup Med Toxicol. 2016;11:50.CrossRefPubMedPubMedCentral
30.
go back to reference Siegrist J, Starke D, Chandola T, Godin I, Marmot M, Niedhammer I, et al. The measurement of effort-reward imbalance at work: European comparisons. Soc Sci Med. 2004;58:1483–99.CrossRefPubMed Siegrist J, Starke D, Chandola T, Godin I, Marmot M, Niedhammer I, et al. The measurement of effort-reward imbalance at work: European comparisons. Soc Sci Med. 2004;58:1483–99.CrossRefPubMed
31.
go back to reference Prümper J, Hartmannsgruber K, Frese M. KFZA - Kurzfragebogen zur Arbeitsanalyse. Zeitschrift für Arbeits- und Organisationspsychologie. 1995;39:125–32. Prümper J, Hartmannsgruber K, Frese M. KFZA - Kurzfragebogen zur Arbeitsanalyse. Zeitschrift für Arbeits- und Organisationspsychologie. 1995;39:125–32.
32.
go back to reference Kuorinka I, Jonsson B, Kilbom A, Vinterberg H, Biering-Sorensen F, Andersson G, et al. Standardised Nordic questionnaires for the analysis of musculoskeletal symptoms. Appl Ergon. 1987;18:233–7.CrossRefPubMed Kuorinka I, Jonsson B, Kilbom A, Vinterberg H, Biering-Sorensen F, Andersson G, et al. Standardised Nordic questionnaires for the analysis of musculoskeletal symptoms. Appl Ergon. 1987;18:233–7.CrossRefPubMed
33.
go back to reference Kristensen TS, Hannerz H, Hogh A, Borg V. The Copenhagen Psychosocial Questionnaire--a tool for the assessment and improvement of the psychosocial work environment. Scand J Work Environ Health. 2005;31:438–49.CrossRefPubMed Kristensen TS, Hannerz H, Hogh A, Borg V. The Copenhagen Psychosocial Questionnaire--a tool for the assessment and improvement of the psychosocial work environment. Scand J Work Environ Health. 2005;31:438–49.CrossRefPubMed
34.
go back to reference Hosmer DW, Lemeshow S. Applied logistic regression. New York: Wiley & Sons; 2000.CrossRef Hosmer DW, Lemeshow S. Applied logistic regression. New York: Wiley & Sons; 2000.CrossRef
35.
go back to reference Siegrist J, Li J. Associations of Extrinsic and Intrinsic Components of Work Stress with Health: A Systematic Review of Evidence on the Effort-Reward Imbalance Model. Int J Environ Res Public Health. 2016;13(4):432.CrossRefPubMedPubMedCentral Siegrist J, Li J. Associations of Extrinsic and Intrinsic Components of Work Stress with Health: A Systematic Review of Evidence on the Effort-Reward Imbalance Model. Int J Environ Res Public Health. 2016;13(4):432.CrossRefPubMedPubMedCentral
36.
go back to reference Aust B, Peter R, Siegrist J. Stress Management in Bus Drivers: A Pilot Study Based on the Model of Effort–Reward Imbalance. Int J Stress Manag. 1997;4(4):297–305.CrossRef Aust B, Peter R, Siegrist J. Stress Management in Bus Drivers: A Pilot Study Based on the Model of Effort–Reward Imbalance. Int J Stress Manag. 1997;4(4):297–305.CrossRef
37.
go back to reference Bourbonnais R, Brisson C, Vinet A, Vezina M, Abdous B, Gaudet M. Effectiveness of a participative intervention on psychosocial work factors to prevent mental health problems in a hospital setting. Occup Environ Med. 2006;63(5):335–42.CrossRefPubMedPubMedCentral Bourbonnais R, Brisson C, Vinet A, Vezina M, Abdous B, Gaudet M. Effectiveness of a participative intervention on psychosocial work factors to prevent mental health problems in a hospital setting. Occup Environ Med. 2006;63(5):335–42.CrossRefPubMedPubMedCentral
38.
go back to reference Simon M, Tackenberg P, Nienhaus A, Estryn-Behar M, Conway PM, Hasselhorn HM. Back or neck-pain-related disability of nursing staff in hospitals, nursing homes and home care in seven countries--results from the European NEXT-Study. Int J Nurs Stud. 2008;45:24–34.CrossRefPubMed Simon M, Tackenberg P, Nienhaus A, Estryn-Behar M, Conway PM, Hasselhorn HM. Back or neck-pain-related disability of nursing staff in hospitals, nursing homes and home care in seven countries--results from the European NEXT-Study. Int J Nurs Stud. 2008;45:24–34.CrossRefPubMed
39.
go back to reference Bernard C, Courouve L, Bouée S, Adjémian A, Chrétien JC, Niedhammer I. Biomechanical and psychosocial work exposures and musculoskeletal symtoms among vineyard workers. J Occup Health. 2011;53:297–311.CrossRefPubMed Bernard C, Courouve L, Bouée S, Adjémian A, Chrétien JC, Niedhammer I. Biomechanical and psychosocial work exposures and musculoskeletal symtoms among vineyard workers. J Occup Health. 2011;53:297–311.CrossRefPubMed
40.
go back to reference von dem Knesebeck O, David K, Siegrist J. Psychosocial stress at work and musculoskeletal pain among police officers in special forces. Gesundheitswesen. 2005;67:674–9.CrossRef von dem Knesebeck O, David K, Siegrist J. Psychosocial stress at work and musculoskeletal pain among police officers in special forces. Gesundheitswesen. 2005;67:674–9.CrossRef
41.
go back to reference Dragano N, von dem Knesebeck O, Rodel A, Siegrist J. Psychosoziale Arbeitsbelastungen und muskulo-skeletale Beschwerden: Bedeutung für die Prävention. J Public Health. 2003;11:196–207.CrossRef Dragano N, von dem Knesebeck O, Rodel A, Siegrist J. Psychosoziale Arbeitsbelastungen und muskulo-skeletale Beschwerden: Bedeutung für die Prävention. J Public Health. 2003;11:196–207.CrossRef
42.
go back to reference Karasek RA. Job Demands, Job Decision Latitude, and Mental Strain: Implications for Job Redesign. Adm Sci Q. 1979;24:285–308.CrossRef Karasek RA. Job Demands, Job Decision Latitude, and Mental Strain: Implications for Job Redesign. Adm Sci Q. 1979;24:285–308.CrossRef
43.
go back to reference Gillen M, Yen IH, Trupin L, Swig L, Rugulies R, Mullen K, et al. The association of socioeconomic status and psychosocial and physical workplace factors with musculoskeletal injury in hospital workers. Am J Ind Med. 2007;50:245–60.CrossRefPubMed Gillen M, Yen IH, Trupin L, Swig L, Rugulies R, Mullen K, et al. The association of socioeconomic status and psychosocial and physical workplace factors with musculoskeletal injury in hospital workers. Am J Ind Med. 2007;50:245–60.CrossRefPubMed
44.
go back to reference Lundberg U, Dohns IE, Melin B, Sandsjö L, Palmerud G, Kadefors R, et al. Psychophysiological stress responses, muscle tension, and neck and shoulder pain among supermarket cashiers. J Occup Health Psychol. 1999;4(3):245.CrossRefPubMed Lundberg U, Dohns IE, Melin B, Sandsjö L, Palmerud G, Kadefors R, et al. Psychophysiological stress responses, muscle tension, and neck and shoulder pain among supermarket cashiers. J Occup Health Psychol. 1999;4(3):245.CrossRefPubMed
45.
go back to reference Schleifer LM, Ley R, Spalding TW. A hyperventilation theory of job stress and musculoskeletal disorders. Am J Ind Med. 2002;41(5):420–32.CrossRefPubMed Schleifer LM, Ley R, Spalding TW. A hyperventilation theory of job stress and musculoskeletal disorders. Am J Ind Med. 2002;41(5):420–32.CrossRefPubMed
46.
go back to reference Theorell T, Emdad R, Arnetz B, Weingarten A. Employee Effects of an Educational Program for Managers at an Insurance Company. Psychosom Med. 2001;63:724–33.CrossRefPubMed Theorell T, Emdad R, Arnetz B, Weingarten A. Employee Effects of an Educational Program for Managers at an Insurance Company. Psychosom Med. 2001;63:724–33.CrossRefPubMed
47.
go back to reference Spence Laschinger HK, Finegan J. Situational and dispositional predictors of nurse manager burnout: a time-lagged analysis. J Nurs Manag. 2008;16:601–7.CrossRefPubMed Spence Laschinger HK, Finegan J. Situational and dispositional predictors of nurse manager burnout: a time-lagged analysis. J Nurs Manag. 2008;16:601–7.CrossRefPubMed
48.
go back to reference Loerbroks A, Meng H, Chen ML, Herr R, Angerer P, Li J. Primary school teachers in China: associations of organizational justice and effort-reward imbalance with burnout and intentions to leave the profession in a cross-sectional sample. Int Arch Occup Environ Health. 2014;87:695–703.CrossRefPubMed Loerbroks A, Meng H, Chen ML, Herr R, Angerer P, Li J. Primary school teachers in China: associations of organizational justice and effort-reward imbalance with burnout and intentions to leave the profession in a cross-sectional sample. Int Arch Occup Environ Health. 2014;87:695–703.CrossRefPubMed
49.
go back to reference Gluschkoff K, Elovainio M, Kinnunen U, Mullola S, Hintsanen M, Keltikangas-Jarvinen L, et al. Work stress, poor recovery and burnout in teachers. Occup Med (Lond). 2016;66:564–70.CrossRef Gluschkoff K, Elovainio M, Kinnunen U, Mullola S, Hintsanen M, Keltikangas-Jarvinen L, et al. Work stress, poor recovery and burnout in teachers. Occup Med (Lond). 2016;66:564–70.CrossRef
50.
51.
go back to reference Wang Y, Ramos A, Wu H, Liu L, Yang X, Wang J, et al. Relationship between occupational stress and burnout among Chinese teachers: a cross-sectional survey in Liaoning. China Int Arch Occup Environ Health. 2015;88:589–97.CrossRefPubMed Wang Y, Ramos A, Wu H, Liu L, Yang X, Wang J, et al. Relationship between occupational stress and burnout among Chinese teachers: a cross-sectional survey in Liaoning. China Int Arch Occup Environ Health. 2015;88:589–97.CrossRefPubMed
52.
go back to reference Chou LP, Li CY, Hu SC. Job stress and burnout in hospital employees: comparisons of different medical professions in a regional hospital in Taiwan. BMJ Open. 2014;4:e004185.CrossRefPubMedPubMedCentral Chou LP, Li CY, Hu SC. Job stress and burnout in hospital employees: comparisons of different medical professions in a regional hospital in Taiwan. BMJ Open. 2014;4:e004185.CrossRefPubMedPubMedCentral
53.
go back to reference Podsakoff PM, MacKenzie SB, Lee JY, Podsakoff NP. Common method biases in behavioral research: a critical review of the literature and recommended remedies. J Appl Psychol. 2003;88:879–903.CrossRefPubMed Podsakoff PM, MacKenzie SB, Lee JY, Podsakoff NP. Common method biases in behavioral research: a critical review of the literature and recommended remedies. J Appl Psychol. 2003;88:879–903.CrossRefPubMed
Metadata
Title
The effect of effort-reward imbalance on the health of childcare workers in Hamburg: a longitudinal study
Authors
Peter Koch
Jan Felix Kersten
Johanna Stranzinger
Albert Nienhaus
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Journal of Occupational Medicine and Toxicology / Issue 1/2017
Electronic ISSN: 1745-6673
DOI
https://doi.org/10.1186/s12995-017-0163-8

Other articles of this Issue 1/2017

Journal of Occupational Medicine and Toxicology 1/2017 Go to the issue