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Published in: Globalization and Health 1/2016

Open Access 01-12-2016 | Research

Bibliometric trends of health economic evaluation in Sub-Saharan Africa

Authors: Karla Hernandez-Villafuerte, Ryan Li, Karen J. Hofman

Published in: Globalization and Health | Issue 1/2016

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Abstract

Background

Collaboration between Sub-Saharan African researchers is important for the generation and transfer of health technology assessment (HTA) evidence, in order to support priority-setting in health. The objective of this analysis was to evaluate collaboration patterns between countries.

Methods

We conducted a rapid evidence assessment that included a random sample of health economic evaluations carried out in 20 countries (Angola, Botswana, Congo, Lesotho, Madagascar, Malawi, Mauritius, Mozambique, Namibia, Seychelles, South Africa, Swaziland, Tanzania, Zambia, Zimbabwe, Ghana, Kenya, Nigeria, Ethiopia, Uganda). We conducted bibliometric network analysis based on all first authors with a Sub-Saharan African academic affiliation and their co-authored publications (“network-articles”). Then we produced a connection map of collaboration patterns among Sub-Saharan African researchers, reflecting the number of network-articles and the country of affiliation of the main co-authors.

Results

The sample of 119 economic evaluations mostly related to treatments of communicable diseases, in particular HIV/AIDS (42/119, 35.29 %) and malaria (26/119, 21.85 %). The 39 first authors from Sub-Saharan African institutions together co-authored 729 network-articles. The network analysis showed weak collaboration between health economic researchers in Sub-Saharan Africa, with researchers being more likely to collaborate with Europe and North America than with other African countries. South Africa stood out as producing the highest number of health economic evaluations and collaborations.

Conclusions

The development and evaluation of HTA research networks in Sub-Saharan Africa should be supported, with South Africa central to any such efforts. Organizations and institutions from high income countries interested in supporting priority setting in Sub-Saharan Africa should include promoting collaboration as part of their agendas, in order to take advantage of the potential transferability of results and methods of the available health economic analyses in Africa and internationally.
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Literature
1.
go back to reference The World Bank. Health expenditure per capita (current US$). 2015. The World Bank. Health expenditure per capita (current US$). 2015.
2.
go back to reference Li R, Hernandez-Villafuerte K, Towse A, Vlad I, Chalkidou K. Mapping priority setting in health in 17 countries across Asia, Latin America, and sub-Saharan Africa. Health Syst Reform. 2016;2(1):71–83.CrossRef Li R, Hernandez-Villafuerte K, Towse A, Vlad I, Chalkidou K. Mapping priority setting in health in 17 countries across Asia, Latin America, and sub-Saharan Africa. Health Syst Reform. 2016;2(1):71–83.CrossRef
3.
go back to reference Rebelo LP. The Origins and the Evolution of Health Economics: a discipline by itself? Led by economists, practitioners or politics? Lisbon: Católica Porto Business School, Universidade Católica Portuguesa; 2007. Rebelo LP. The Origins and the Evolution of Health Economics: a discipline by itself? Led by economists, practitioners or politics? Lisbon: Católica Porto Business School, Universidade Católica Portuguesa; 2007.
4.
go back to reference WHO. Health intervention and technology assessment in support of universal health coverage. Geneva: World Health Organization (WHO); 2014 WHA67.23. WHO. Health intervention and technology assessment in support of universal health coverage. Geneva: World Health Organization (WHO); 2014 WHA67.23.
5.
go back to reference Jakovljevic MM, Ogura S. Health Economics at the crossroads of centuries–from the past to the future. Front Public Health. 2016;4:115.PubMed Jakovljevic MM, Ogura S. Health Economics at the crossroads of centuries–from the past to the future. Front Public Health. 2016;4:115.PubMed
6.
go back to reference CDR. CRD Database. In: University of York, editor. Centre for Reviews and Dissemination. 2015. CDR. CRD Database. In: University of York, editor. Centre for Reviews and Dissemination. 2015.
7.
go back to reference Garrison LP, Babigumira J, Bartlein R, Nguyen H. Health Technology Assessment in Low- and Middle-Income Countries: Finding from a Survey and Case Studies. Submitted to the U.S. Agency for International Development by the Strengthening Pharmaceutical Systems (SPS) Program. Arlington VA: Management Sciences for Health; 2012. Garrison LP, Babigumira J, Bartlein R, Nguyen H. Health Technology Assessment in Low- and Middle-Income Countries: Finding from a Survey and Case Studies. Submitted to the U.S. Agency for International Development by the Strengthening Pharmaceutical Systems (SPS) Program. Arlington VA: Management Sciences for Health; 2012.
8.
go back to reference Chuang K-Y, Chuang Y-C, Ho M, Ho Y-S. Bibliometric analysis of public health research in Africa: The overall trend and regional comparisons. S Afr J Sci. 2011;107(5/6):1–6. Chuang K-Y, Chuang Y-C, Ho M, Ho Y-S. Bibliometric analysis of public health research in Africa: The overall trend and regional comparisons. S Afr J Sci. 2011;107(5/6):1–6.
9.
go back to reference Hofman KJ, Kanyengo CW, Rapp BA, Kotzin S. Mapping the health research landscape in Sub-Saharan Africa: a study of trends in biomedical publications. J Med Libr Assoc. 2009;97(1):41–4.CrossRefPubMedPubMedCentral Hofman KJ, Kanyengo CW, Rapp BA, Kotzin S. Mapping the health research landscape in Sub-Saharan Africa: a study of trends in biomedical publications. J Med Libr Assoc. 2009;97(1):41–4.CrossRefPubMedPubMedCentral
10.
go back to reference Wagstaff A, Culyer AJ. Four decades of health economics through a bibliometric lens. J Health Econ. 2012;31(2):406–39.CrossRefPubMed Wagstaff A, Culyer AJ. Four decades of health economics through a bibliometric lens. J Health Econ. 2012;31(2):406–39.CrossRefPubMed
11.
go back to reference Towse A, Devlin N, Hawe E, Garrison L. The Evolution of HTA in Emerging Markets Health Care Systems: Analysis to Support a Policy Response. Office of Health Economics, Consulting report, 2011. Towse A, Devlin N, Hawe E, Garrison L. The Evolution of HTA in Emerging Markets Health Care Systems: Analysis to Support a Policy Response. Office of Health Economics, Consulting report, 2011.
12.
go back to reference Jenniskens F, Tiendrebeogo G, Coolen A, Blok L, Kouanda S, Sataru F, et al. How countries cope with competing demands and expectations: perspectives of different stakeholders on priority setting and resource allocation for health in the era of HIV and AIDS. BMC Public Health. 2012;12(1071). doi:10.1186/1471-2458-12-1071. Jenniskens F, Tiendrebeogo G, Coolen A, Blok L, Kouanda S, Sataru F, et al. How countries cope with competing demands and expectations: perspectives of different stakeholders on priority setting and resource allocation for health in the era of HIV and AIDS. BMC Public Health. 2012;12(1071). doi:10.​1186/​1471-2458-12-1071.
13.
go back to reference Kularatna S, Whitty JA, Johnson NW, Scuffham PA. Health state valuation in low- and middle- income countries: a systematic review of the literature. Value Health. 2013;16(6):1091–9.CrossRefPubMed Kularatna S, Whitty JA, Johnson NW, Scuffham PA. Health state valuation in low- and middle- income countries: a systematic review of the literature. Value Health. 2013;16(6):1091–9.CrossRefPubMed
14.
go back to reference Ankrah E. Systematic review of economic evaluation literature in Ghana: Is Health Technology Assessment the future? Value in Health Regional. 2013;2(2):279–83.CrossRef Ankrah E. Systematic review of economic evaluation literature in Ghana: Is Health Technology Assessment the future? Value in Health Regional. 2013;2(2):279–83.CrossRef
15.
go back to reference HTAsiaLink. Current collaborative projects: Asia Study on Value of a QALY. 2015. HTAsiaLink. Current collaborative projects: Asia Study on Value of a QALY. 2015.
17.
go back to reference Lachat C, Roberfroid D, Van den Broeck L, Van den Briel N, Nago E, Kruger A, et al. A decade of nutrition research in Africa: assessment of the evidence base and academic collaboration. Public Health Nutr. 2015;18(10):1890–97. Lachat C, Roberfroid D, Van den Broeck L, Van den Briel N, Nago E, Kruger A, et al. A decade of nutrition research in Africa: assessment of the evidence base and academic collaboration. Public Health Nutr. 2015;18(10):1890–97.
18.
go back to reference Ettarh RR. Institution-level collaboration in cardiovascular research in sub-Saharan Africa. Cardiovasc Diagn Ther. 2015;5(4):311–5.PubMedPubMedCentral Ettarh RR. Institution-level collaboration in cardiovascular research in sub-Saharan Africa. Cardiovasc Diagn Ther. 2015;5(4):311–5.PubMedPubMedCentral
19.
go back to reference Atkinson P, Batchelor C, Parsons E. Trajectories of collaboration and competition in a medical discovery. Sci Technol Hum Values. 1998;23(3):259–84.CrossRef Atkinson P, Batchelor C, Parsons E. Trajectories of collaboration and competition in a medical discovery. Sci Technol Hum Values. 1998;23(3):259–84.CrossRef
20.
go back to reference Cockburn I. Public-Private Interaction and the Productivity of Pharmaceutical Research. NBER Working Paper. Cambridge: National Bureau of Economic Research; 1997. p. 6018. Cockburn I. Public-Private Interaction and the Productivity of Pharmaceutical Research. NBER Working Paper. Cambridge: National Bureau of Economic Research; 1997. p. 6018.
21.
go back to reference Fershtman C, Gandal N. Direct and indirect knowledge spillovers: the “social network” of open-source projects. RAND J Econ. 2014;42(1):70–91.CrossRef Fershtman C, Gandal N. Direct and indirect knowledge spillovers: the “social network” of open-source projects. RAND J Econ. 2014;42(1):70–91.CrossRef
22.
go back to reference Hoekman J, Frenken K, van Oort F. Collaboration networks as carriers of knowledge spillovers: Evidence from EU27 regions. DIME Working paper. 2008 3.2. Hoekman J, Frenken K, van Oort F. Collaboration networks as carriers of knowledge spillovers: Evidence from EU27 regions. DIME Working paper. 2008 3.2.
23.
go back to reference Tang L, Guangyuan H. Tracing the footprint of knowledge spillover: Evidence from U.S.–China collaboration in nanotechnology. J Am Soc Inf Sci Technol. 2013;64(9):1791–801.CrossRef Tang L, Guangyuan H. Tracing the footprint of knowledge spillover: Evidence from U.S.–China collaboration in nanotechnology. J Am Soc Inf Sci Technol. 2013;64(9):1791–801.CrossRef
24.
go back to reference Glanzel W, Schubert A. Analysing scientific networks through co-authorship. Handbook of Quantitative Science and Technology Research: The Use of Publication and Patent Statistics in Studies of S&T Systems. London: Kluwer; 2004. p. 257–76. Glanzel W, Schubert A. Analysing scientific networks through co-authorship. Handbook of Quantitative Science and Technology Research: The Use of Publication and Patent Statistics in Studies of S&T Systems. London: Kluwer; 2004. p. 257–76.
25.
go back to reference Melin G, Persson O. Studying research collaboration using co-authorships. Scientometrics. 1996;36(3):363–77.CrossRef Melin G, Persson O. Studying research collaboration using co-authorships. Scientometrics. 1996;36(3):363–77.CrossRef
26.
go back to reference Zare-Farashbandi F, Geraei E, Siamaki S. Study of co-authorship network of papers in the Journal of Research in Medical Sciences using social network analysis. J Res Med Sci. 2014;19(1):41–6.PubMedPubMedCentral Zare-Farashbandi F, Geraei E, Siamaki S. Study of co-authorship network of papers in the Journal of Research in Medical Sciences using social network analysis. J Res Med Sci. 2014;19(1):41–6.PubMedPubMedCentral
27.
go back to reference Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Inf Libr J. 2009;26:91–108.CrossRef Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Inf Libr J. 2009;26:91–108.CrossRef
28.
go back to reference Thomas J, Newman M, Oliver S. Rapid evidence assessments of research to inform social policy: taking stock and moving forward. Evid Policy. 2013;9(1):5–27.CrossRef Thomas J, Newman M, Oliver S. Rapid evidence assessments of research to inform social policy: taking stock and moving forward. Evid Policy. 2013;9(1):5–27.CrossRef
29.
go back to reference Curry LA, Byam P, Linnander E, Andersson KM, Abebe Y, Zerihun A, et al. Evaluation of the Ethiopian Millennium Rural Initiative: impact on mortality and cost-effectiveness. PLoS One. 2013;8(11):e79847.CrossRefPubMedPubMedCentral Curry LA, Byam P, Linnander E, Andersson KM, Abebe Y, Zerihun A, et al. Evaluation of the Ethiopian Millennium Rural Initiative: impact on mortality and cost-effectiveness. PLoS One. 2013;8(11):e79847.CrossRefPubMedPubMedCentral
30.
go back to reference Hu D, Grossman D, Levin C, Blanchard K, Adanu R, Goldie SJ. Cost-effectiveness analysis of unsafe abortion and alternative first-trimester pregnancy termination strategies in Nigeria and Ghana. Afr J Reprod Health. 2014;14(2):85–103. Hu D, Grossman D, Levin C, Blanchard K, Adanu R, Goldie SJ. Cost-effectiveness analysis of unsafe abortion and alternative first-trimester pregnancy termination strategies in Nigeria and Ghana. Afr J Reprod Health. 2014;14(2):85–103.
31.
go back to reference Hansen KS, Chapman G. Setting priorities for the health care sector in Zimbabwe using cost-effectiveness analysis and estimates of the burden of disease. Cost Eff Resour Alloc. 2008;6(1):1.CrossRef Hansen KS, Chapman G. Setting priorities for the health care sector in Zimbabwe using cost-effectiveness analysis and estimates of the burden of disease. Cost Eff Resour Alloc. 2008;6(1):1.CrossRef
32.
go back to reference Ndindjock R, Gedeon J, Mendis S, Paccaud F, Bovet P. Potential impact of single-risk-factor versus total risk management for the prevention of cardiovascular events in Seychelles. Bull World Health Organ. 2011;89(4):286–95.CrossRefPubMedPubMedCentral Ndindjock R, Gedeon J, Mendis S, Paccaud F, Bovet P. Potential impact of single-risk-factor versus total risk management for the prevention of cardiovascular events in Seychelles. Bull World Health Organ. 2011;89(4):286–95.CrossRefPubMedPubMedCentral
33.
go back to reference Ekwunife OI, Okafor CE, Ezenduka CC, Udeogaranya PO. Cost-utility analysis of antihypertensive medications in Nigeria: a decision analysis. Cost Effectiveness and Resource Allocation. 2013;11(2). doi:10.1186/1478-7547-11-2. Ekwunife OI, Okafor CE, Ezenduka CC, Udeogaranya PO. Cost-utility analysis of antihypertensive medications in Nigeria: a decision analysis. Cost Effectiveness and Resource Allocation. 2013;11(2). doi:10.​1186/​1478-7547-11-2.
34.
go back to reference Granich R, Kahn JG, Bennett R, Holmes CB, Garg N, Serenata C, et al. Expanding ART for treatment and prevention of HIV in South Africa: estimated cost and cost-effectiveness 2011-2050. PLoS One. 2012;7(2):e30216.CrossRefPubMedPubMedCentral Granich R, Kahn JG, Bennett R, Holmes CB, Garg N, Serenata C, et al. Expanding ART for treatment and prevention of HIV in South Africa: estimated cost and cost-effectiveness 2011-2050. PLoS One. 2012;7(2):e30216.CrossRefPubMedPubMedCentral
35.
go back to reference Pretorius C, Stover J, Bollinger L, Bacaër N, Williams B. Evaluating the cost-effectiveness of pre-exposure prophylaxis (PrEP) and its impact on HIV-1 transmission in South Africa. PLoS One. 2010;5(11):e13646.CrossRefPubMedPubMedCentral Pretorius C, Stover J, Bollinger L, Bacaër N, Williams B. Evaluating the cost-effectiveness of pre-exposure prophylaxis (PrEP) and its impact on HIV-1 transmission in South Africa. PLoS One. 2010;5(11):e13646.CrossRefPubMedPubMedCentral
36.
go back to reference Robberstad B, Evjen-Olsen B. Preventing mother to child transmission of HIV with highly active antiretroviral treatment in Tanzania-a prospective cost-effectiveness study. J Acquir Immune Defic Syndr. 2010;55(3):397–403.CrossRefPubMed Robberstad B, Evjen-Olsen B. Preventing mother to child transmission of HIV with highly active antiretroviral treatment in Tanzania-a prospective cost-effectiveness study. J Acquir Immune Defic Syndr. 2010;55(3):397–403.CrossRefPubMed
37.
go back to reference Nichols BE, Baltussen R, van Dijk JH, Thuma PE, Nouwen JL, Boucher CA, et al. Cost-effectiveness of PrEP in HIV/AIDS control in Zambia: a stochastic league approach. J Acquir Immune Defic Syndr. 2014;66(2):221–8.PubMed Nichols BE, Baltussen R, van Dijk JH, Thuma PE, Nouwen JL, Boucher CA, et al. Cost-effectiveness of PrEP in HIV/AIDS control in Zambia: a stochastic league approach. J Acquir Immune Defic Syndr. 2014;66(2):221–8.PubMed
38.
go back to reference Ishikawa N, Shimbo T, Miyano S, Sikazwe I, Mwango A, Ghidinelli MN, et al. Health outcomes and cost impact of the new WHO 2013 guidelines on prevention of mother-to-child transmission of HIV in Zambia. PLoS One. 2014;9(3):e90991.CrossRefPubMedPubMedCentral Ishikawa N, Shimbo T, Miyano S, Sikazwe I, Mwango A, Ghidinelli MN, et al. Health outcomes and cost impact of the new WHO 2013 guidelines on prevention of mother-to-child transmission of HIV in Zambia. PLoS One. 2014;9(3):e90991.CrossRefPubMedPubMedCentral
39.
go back to reference Nichols BE, Boucher CA, van Dijk JH, Thuma PE, Nouwen JL, Baltussen R, et al. Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study. PLoS One. 2013;8(3):e59549.CrossRefPubMedPubMedCentral Nichols BE, Boucher CA, van Dijk JH, Thuma PE, Nouwen JL, Baltussen R, et al. Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study. PLoS One. 2013;8(3):e59549.CrossRefPubMedPubMedCentral
40.
go back to reference Ryan M, Griffin S, Chitah B, Walker AS, Mulenga V, Kalolo D, et al. The cost-effectiveness of cotrimoxazole prophylaxis in HIV-infected children in Zambia. Aids. 2008;22(6):749–57.CrossRefPubMed Ryan M, Griffin S, Chitah B, Walker AS, Mulenga V, Kalolo D, et al. The cost-effectiveness of cotrimoxazole prophylaxis in HIV-infected children in Zambia. Aids. 2008;22(6):749–57.CrossRefPubMed
41.
go back to reference Ciaranello AL, Perez F, Engelsmann B, Walensky RP, Mushavi A, Rusibamayila A, et al. Cost-effectiveness of World Health Organization 2010 guidelines for prevention of mother-to-child HIV transmission in Zimbabwe. Clin Infect Dis. 2013;56(3):430–46.CrossRefPubMed Ciaranello AL, Perez F, Engelsmann B, Walensky RP, Mushavi A, Rusibamayila A, et al. Cost-effectiveness of World Health Organization 2010 guidelines for prevention of mother-to-child HIV transmission in Zimbabwe. Clin Infect Dis. 2013;56(3):430–46.CrossRefPubMed
42.
go back to reference Puett C, Salpéteur C, Lacroix E, Zimunya SD, Israël A-D, Aït-Aïssa M. Cost-effectiveness of community vegetable gardens for people living with HIV in Zimbabwe. Cost Eff Resour Alloc. 2014;12(1):1.CrossRef Puett C, Salpéteur C, Lacroix E, Zimunya SD, Israël A-D, Aït-Aïssa M. Cost-effectiveness of community vegetable gardens for people living with HIV in Zimbabwe. Cost Eff Resour Alloc. 2014;12(1):1.CrossRef
43.
go back to reference Shrestha R, Mugisha B, Bunnell R, Mermin J, Odeke R, Madra P, et al. Cost-utility of tuberculosis prevention among HIV-infected adults in Kampala, Uganda. Int J Tuberc Lung Dis. 2007;11(7):747–54.PubMed Shrestha R, Mugisha B, Bunnell R, Mermin J, Odeke R, Madra P, et al. Cost-utility of tuberculosis prevention among HIV-infected adults in Kampala, Uganda. Int J Tuberc Lung Dis. 2007;11(7):747–54.PubMed
44.
go back to reference International Scientific Institute (SCI). SCI Impact Factor List. 2014. International Scientific Institute (SCI). SCI Impact Factor List. 2014.
45.
go back to reference BIOMEDCENTRAL. Cost Effectiveness and Resource Allocation. 2015. BIOMEDCENTRAL. Cost Effectiveness and Resource Allocation. 2015.
46.
go back to reference Beattie P, Renshaw M, Davies CS. Strengthening health research in the developing world malaria research capacity in Africa. Prepared by the Wellcome Trust Multilateral Iniciative on Malaria, 2006. Beattie P, Renshaw M, Davies CS. Strengthening health research in the developing world malaria research capacity in Africa. Prepared by the Wellcome Trust Multilateral Iniciative on Malaria, 2006.
47.
go back to reference Onyancha OB. Authorship patterns of the literature on HIV/AIDS in Eastern and Southern Africa: an exposition of the responsible authors, institutions and countries, 1980-2005. S Afr J Libr Inf Sci. 2008;74(1):9–22. Onyancha OB. Authorship patterns of the literature on HIV/AIDS in Eastern and Southern Africa: an exposition of the responsible authors, institutions and countries, 1980-2005. S Afr J Libr Inf Sci. 2008;74(1):9–22.
49.
go back to reference WHO. The health of the people: what works – the African Regional Health Report 2014. World Health Organization (WHO), Regional Office for Africa. 2014. WHO. The health of the people: what works – the African Regional Health Report 2014. World Health Organization (WHO), Regional Office for Africa. 2014.
50.
go back to reference HIV/AIDS JUNPo. Global report: UNAIDS report on the global AIDS epidemic 2010: UNAIDS; 2010. HIV/AIDS JUNPo. Global report: UNAIDS report on the global AIDS epidemic 2010: UNAIDS; 2010.
51.
go back to reference World Health Organization. World malaria report 2015. 2016. World Health Organization. World malaria report 2015. 2016.
52.
go back to reference The Global Fund. Global Reach, local impact - with 468 active grants in over 100 Countries, implemented by local experts 2016 [cited 2016 11/02]. The Global Fund. Global Reach, local impact - with 468 active grants in over 100 Countries, implemented by local experts 2016 [cited 2016 11/02].
55.
go back to reference MRC. Outputs, Outcomes and Impact of MRC Research: 2012 Report. London: Medical Research Council (MRC), 2010. MRC. Outputs, Outcomes and Impact of MRC Research: 2012 Report. London: Medical Research Council (MRC), 2010.
Metadata
Title
Bibliometric trends of health economic evaluation in Sub-Saharan Africa
Authors
Karla Hernandez-Villafuerte
Ryan Li
Karen J. Hofman
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Globalization and Health / Issue 1/2016
Electronic ISSN: 1744-8603
DOI
https://doi.org/10.1186/s12992-016-0188-2

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