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Journal of NeuroEngineering and Rehabilitation

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Open Access 01-12-2016 | Research

EEG response varies with lesion location in patients with chronic stroke

Authors: Wanjoo Park, Gyu Hyun Kwon, Yun-Hee Kim, Jong-Hwan Lee, Laehyun Kim

Published in: Journal of NeuroEngineering and Rehabilitation | Issue 1/2016

Abstract

Background

Brain activation differs according to lesion location in functional magnetic resonance imaging (fMRI) studies, but lesion location-dependent electroencephalographic (EEG) alterations are unclear. Because of the increasing use of EEG-based brain-computer-interface rehabilitation, we examined lesion location-dependent EEG patterns in patients with stroke while they performed motor tasks.

Methods

Twelve patients with chronic stroke were divided into three subgroups according to their lesion locations: supratentorial lesions that included M1 (SM1+), supratentorial lesions that excluded M1 (SM1-), and infratentorial (INF) lesions. Participants performed three motor tasks [active, passive, and motor imagery (MI)] with supination and grasping movements. The hemispheric asymmetric indexes, which were calculated with laterality coefficients (LCs), the temporal changes in the event-related desynchronization (ERD) patterns in the bilateral motor cortex, and the topographical distributions in the 28-channel EEG patterns around the supplementary motor area and bilateral motor cortex of the three participant subgroups were compared with those of the 12 age-matched healthy controls.

Results

The SM1+ group exhibited negative LC values in the active and MI motor tasks, while the other patient subgroups exhibited positive LC values. Negative LC values indicate that the ERD/ERS intensity of the ipsilateral hemisphere is higher than the contralateral hemisphere, whereas positive LC values indicate that the ERD/ERS intensity of the contralateral hemisphere is higher than the ipsilateral hemisphere. The LC values of SM1+ and healthy controls differed significantly (rank-sum test, p < 0.05) in both the supination and grasping movements in the active task. The three patient subgroups differed distinctly from each other in the topography analysis.

Conclusions

The hemispheric asymmetry and topographic characteristics of the beta band power patterns in the patients with stroke differed according to the location of the lesion, which suggested that EEG analyses of neurorehabilitation should be implemented according to lesion location.

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Title: EEG response varies with lesion location in patients with chronic stroke
Authors: Wanjoo Park
Gyu Hyun Kwon
Yun-Hee Kim
Jong-Hwan Lee
Laehyun Kim
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Journal of NeuroEngineering and Rehabilitation / Issue 1/2016
Electronic ISSN: 1743-0003
DOI: https://doi.org/10.1186/s12984-016-0120-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

EEG response varies with lesion location in patients with chronic stroke

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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