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Journal of the International Society of Sports Nutrition

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Open Access 01-12-2018 | Research article

The effect of carbohydrate mouth rinse on performance, biochemical and psychophysiological variables during a cycling time trial: a crossover randomized trial

Authors: Amanda M. J. Ferreira, Luiz F. Farias-Junior, Thaynan A. A. Mota, Hassan M. Elsangedy, Aline Marcadenti, Telma M. A. M. Lemos, Alexandre H. Okano, Ana P. T. Fayh

Published in: Journal of the International Society of Sports Nutrition | Issue 1/2018

Abstract

Background

The hypothesis of the central effect of carbohydrate mouth rinse (CMR) on performance improvement in a fed state has not been established, and its psychophysiological responses have not yet been described. The aim of this study was to evaluate the effect of CMR in athletes fed state on performance, biochemical and psychophysiological responses compared to ad libitum water intake.

Methods

Eleven trained male cyclists completed a randomized, crossover trial, which consisted of a 30 km cycle ergometer at self-selected intensity and in a fed state. Subjects were under random influence of the following interventions: CMR with a 6% unflavored maltodextrin solution; mouth rinsing with a placebo solution (PMR); drinking “ad libitum” (DAL). The time for completion of the test (min), heart rate (bpm) and power (watts), rating of perceived exertion (RPE), affective response, blood glucose (mg/dL) and lactate (mmol/DL), were evaluated before, during and immediately after the test, while insulin (uIL/mL), cortisol (μg/dL) and creatine kinase (U/L) levels were measured before, immediately after the test and 30 min after the test.

Results

Time for completion of the 30 km trial did not differ significantly among CMR, PMR and DAL interventions (means = 54.5 ± 2.9, 54.7 ± 2.9 and 54.5 ± 2.5 min, respectively; p = 0.82). RPE and affective response were higher in DAL intervention (p < 0.01). Glucose, insulin, cortisol and creatine kinase responses showed no significant difference among interventions.

Conclusions

In a fed state, CMR has not caused metabolic changes, and it has not improved physical performance compared to ad libitum water intake, but demonstrated a possible central effect. ReBec registration number: RBR-4vpwkg. Available in http://www.ensaiosclinicos.gov.br/rg/?q=RBR-4vpwkg.

Thomas D, Erdman K, Burke L. American college of sports medicine joint position statement. Nutrition and athletic performance. Med Sci Sport Exerc. 2016;48:543–68. https://doi.org/10.1249/MSS.0000000000000852.

Jeukendrup A. A step towards personalized sports nutrition: carbohydrate intake during exercise. Sport Med. 2014;44:S25–33. https://doi.org/10.1007/s40279-014-0148-z.CrossRef

Winnick JJ, Davis JM, Welsh RS, Carmichael MD, Murphy EA, Blackmon JA. Carbohydrates feedings during team sport exercise preserve physical and CNS function. Med Sci Sports Exerc. 2005;37:306–15. https://doi.org/10.1249/01.MSS.0000152803.35130.A4.CrossRefPubMed

Coyle EF, Coggan a R, Hemmert MK, Ivy JL. Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. J Appl Physiol. 1986;61:165–72.CrossRefPubMed

Torrens SL, Areta JL, Parr EB, Hawley JA. Carbohydrate dependence during prolonged simulated cycling time trials. Eur J Appl Physiol. 2016;116:781–90. https://doi.org/10.1007/s00421-016-3333-y.CrossRefPubMed

Correia-Oliveira CR, Bertuzzi R, Kiss MAPD, Lima-Silva AE. Strategies of dietary carbohydrate manipulation and their effects on performance in cycling time trials. Sport Med. 2013;43:707–19. https://doi.org/10.1007/s40279-013-0054-9.CrossRef

Carter JM, Jeukendrup AE, Mann CH, Jones D a. The effect of glucose infusion on glucose kinetics during a 1-h time trial. Med Sci Sports Exerc. 2004;36:1543–50. https://doi.org/10.1249/01.MSS.0000139892.69410.D8.CrossRefPubMed

Casa DJ, Armstrong LE, Hillman SK, Montain SJ, Reiff RV, Rich BSE, et al. National Athletic Trainers’ Association position statement: fluid replacement for athletes. J Athl Train. 2000;35:212–24. https://doi.org/10.4085/1062-6050-48.2.25.PubMedPubMedCentral

Wall BA, Watson G, Peiffer JJ, Abbiss CR, Siegel R, Laursen PB. Current hydration guidelines are erroneous: dehydration does not impair exercise performance in the heat. Br J Sports Med. 2013:1–8. https://doi.org/10.1136/bjsports-2013-092417.

10.

Berkulo M a R, Bol S, Levels K, Lamberts RP, Daanen H a M, Noakes TD. Ad-libitum drinking and performance during a 40-km cycling time trial in the heat. Eur J Sport Sci. 2015:1–8. https://doi.org/10.1080/17461391.2015.1009495.

11.

Noakes TD. Drinking guidelines for exercise: what evidence is there that athletes should drink “as much as tolerable”, “to replace the weight lost during exercise” or “ad libitum”? J Sports Sci. 2007;25:781–96. https://doi.org/10.1080/02640410600875036.CrossRefPubMed

12.

Carter JM, Jeukendrup AE, Jones D a. The effect of carbohydrate mouth rinse on 1-h cycle time trial performance. Med Sci Sports Exerc. 2004;36:2107–11. https://doi.org/10.1249/01.MSS.0000147585.65709.6F.CrossRefPubMed

13.

Rollo I, Williams C, Gant N, Nute M. The influence of carbohydrate mouth rinse on self-selected speeds during a 30-min treadmill run. Int J Sport Nutr Exerc Metab. 2008;18:585–600. https://doi.org/10.1123/ijsnem.18.6.585.CrossRefPubMed

14.

Chambers ES, Bridge MW, Jones D a. Carbohydrate sensing in the human mouth: effects on exercise performance and brain activity. J Physiol. 2009;587:1779–94. https://doi.org/10.1113/jphysiol.2008.164285.CrossRefPubMedPubMedCentral

15.

Pottier A, Bouckaert J, Gilis W, Roels T, Derave W. Mouth rinse but not ingestion of a carbohydrate solution improves 1-h cycle time trial performance. Scand J Med Sci Sport. 2010;20:105–11. https://doi.org/10.1111/j.1600-0838.2008.00868.x.CrossRef

16.

Fares EJM, Kayser B. Carbohydrate mouth rinse effects on exercise capacity in pre- and postprandial states. J Nutr Metab. 2011;2011 https://doi.org/10.1155/2011/385962.

17.

Lane SC, Bird SR, Burke LM, Hawley J a. Effect of a carbohydrate mouth rinse on simulated cycling time-trial performance commenced in a fed or fasted state. Appl Physiol Nutr Metab. 2013;38:134–9. https://doi.org/10.1139/apnm-2012-0300.CrossRefPubMed

18.

Turner CE, Byblow WD, Stinear CM, Gant N. Carbohydrate in the mouth enhances activation of brain circuitry involved in motor performance and sensory perception. Appetite. 2014;80:212–9. https://doi.org/10.1016/j.appet.2014.05.020.CrossRefPubMed

19.

Bortolotti H, Altimari LR, Costa MV, Cyrino ES. Mouth rinse with carbohydrate drink and performance: hypothesis of its central action. Int Sport J. 2014;15:84–95.

20.

Devenney S, Mangan S, Shortall M, Collins K. Effects of carbohydrate mouth rinse and caffeine on high-intensity interval running in a fed state. Appl Physiol Nutr Metab. 2017:1-5. https://doi.org/10.1139/apnm-2017-0458.

21.

Ispoglou T, O’Kelly D, Angelopoulou A, Bargh M, O’Hara JP, Duckworth LC. Mouth-rinsing with carbohydrate solutions at the postprandial state fail to improve performance during simulated cycling time trials. J Strength Cond Res. 2015;29:2316–25. https://doi.org/10.1519/JSC.0000000000000882.CrossRefPubMed

22.

Whitham M, McKinney J, Street M, Wt L, Kinney JMC. Effect of a carbohydrate mouthwash on running time-trial performance. J Sports Sci. 2007;25:1385–92. https://doi.org/10.1080/02640410601113676.CrossRefPubMed

23.

Beelen M, Berghuis J, Bonaparte B, Ballak SB, Jeukendrup AE, Van Loon LJC. Carbohydrate mouth rinsing in the fed state: lack of enhancement of time-trial performance. Int J Sport Nutr Exerc Metab. 2009;19:400–9. https://doi.org/10.1123/ijsnem.19.4.400.CrossRefPubMed

24.

Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. Exercise and fluid replacement. Med Sci Sports Exerc. 2007;39:377–90. https://doi.org/10.1249/mss.0b013e31802ca597.CrossRefPubMed

25.

World Health Organization WHO. Obesity: preventing and managing the global epidemic. Geneva; 2000. Available in: http://www.who.int/nutrition/publications/obesity/WHO_TRS_894/en/. Accessed 27 Apr 2018.

26.

Jackson AS, Pollock ML. Generalized equations for predicting body density of men. Br J Nutr. 1978;40:497–504. https://doi.org/10.1079/BJN19780152.CrossRefPubMed

27.

Siri WE. Body composition from fluid spaces and density: analysis of methods. In: techniques for measuring body composition. Vol. 9. Washington, DC: National Academy of Sciences; 1961.

28.

Midgley AW, Carroll S, Marchant D, McNaughton LR, Siegler J. Evaluation of true maximal oxygen uptake based on a novel set of standardized criteria. Appl Physiol Nutr Metab. 2009;34:115–23. https://doi.org/10.1139/H08-146.CrossRefPubMed

29.

Gam S, Guelfi KJ, Fournier P a. Opposition of carbohydrate in a mouth-rinse solution to the detrimental effect of mouth rinsing during cycling time trials. Int J Sport Nutr Exerc Metab. 2012:48–56. https://doi.org/10.1123/ijsnem.23.1.48.

30.

Borg G. Psychophysical bases of perceived exertion. Med Sci Sport Exerc. 1982;14:377–81.

31.

Hardy CJ, Rejeski WJ. Not what, but how one feels: the measurement of affect during exercise. J Sport E Exerc Psychol. 1989;11:304–17. https://doi.org/10.1123/jsep.11.3.304.CrossRef

32.

Stannard SR, Buckley AJ, Edge JA, Thompson MW. Adaptations to skeletal muscle with endurance exercise training in the acutely fed versus overnight-fasted state. J Sci Med Sport. 2010;13:465–9. https://doi.org/10.1016/j.jsams.2010.03.002.CrossRefPubMed

33.

Ali A, Yoo MJY, Moss C, Breier BH. Carbohydrate mouth rinsing has no effect on power output during cycling in a glycogen-reduced state. J Int Soc Sports Nutr. 2016:1–10. https://doi.org/10.1186/s12970-016-0131-1.

34.

Okano AH, Montenegro RA, Farinatti PDTV, Li LM, Brunoni AR, Fontes EB. Estimulação cerebral na promoção da saúde e melhoria do desempenho físico. Rev Bras Educ Física E Esporte. 2013;27:315–32. https://doi.org/10.1590/S1807-55092013005000009.CrossRef

35.

Fontes EB, Smirmaul BPC, Nakamura FY, Pereira G, Okano AH, Altimari LR, et al. The relationship between rating of perceived exertion and muscle activity during exhaustive constant-load cycling. Int J Sports Med. 2010;31:683–8. https://doi.org/10.1055/s-0030-1255108.CrossRefPubMed

36.

Lagally KM, Robertson RJ, Gallagher KI, Goss FL, Jakici JM, Lephart SM, et al. Perceived exertion, electromyography, and blood lactate during acute bouts of resistance exercise. Med Sci Sport Exerc. 2012;43:14–22.

37.

Tucker R. The anticipatory regulation of performance: the physiological basis for pacing strategies and the development of a perception-based model for exercise performance. Br J Sports Med. 2009;43:392–400. https://doi.org/10.1136/bjsm.2008.050799.CrossRefPubMed

38.

Noakes TD, St Clair Gibson A, Lambert EV. From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions. Br J Sports Med. 2005;39:120–4. https://doi.org/10.1136/bjsm.2003.010330.CrossRefPubMedPubMedCentral

39.

Cole K, Costill D. Effect of caffeine ingestion on perception of effort and subsequent work production. Int J Sport Nutr. 1996;6:14–21.CrossRefPubMed

40.

Backhouse SH, Bishop NC, Biddle SJH, Williams C. Effect of carbohydrate and prolonged exercise on affect and perceived exertion. Med Sci Sports Exerc. 2005;37:1768–73. https://doi.org/10.1249/01.mss.0000181837.77380.80.CrossRefPubMed

41.

Chong E, Guelfi KJ, Fournier P a. Effect of a carbohydrate mouth rinse on maximal sprint performance in competitive male cyclists. J Sci Med Sport. 2011;14:162–7. https://doi.org/10.1016/j.jsams.2010.08.003.CrossRefPubMed

42.

Lange F, Eggert F. Sweet delusion. Glucose drinks fail to counteract ego depletion. Appetite. 2014;75:54–63. https://doi.org/10.1016/j.appet.2013.12.020.CrossRefPubMed

43.

Cramer MN, Thompson MW, Périard JD. Thermal and cardiovascular strain mitigate the potential benefit of carbohydrate mouth rinse during self-paced exercise in the heat. Front Physiol. 2015;6:1–9. https://doi.org/10.3389/fphys.2015.00354.CrossRef

44.

Goulet EDB. Effect of exercise-induced dehydration on time-trial exercise performance: a meta-analysis. Br J Sports Med. 2011;45:1149–56. https://doi.org/10.1136/bjsm.2010.077966.CrossRefPubMed

45.

Cheung SS, Mcgarr GW, Mallette MM, Wallace PJ, Watson CL, Kim IM, et al. Separate and combined effects of dehydration and thirst sensation on exercise performance in the heat. Scand J Med Sci Sport. 2015;25:104–11. https://doi.org/10.1111/sms.12343.CrossRef

46.

Cherrington AD, Sindelar D, Edgerton D, Steiner K, McGuinness OP. Physiological consequences of phasic insulin release in the normal animal. Diabetes. 2002;51:103–8. https://doi.org/10.2337/diabetes.51.2007.S103.CrossRef

47.

Murray KO, Paris HL, Fly AD, Chapman RF, Timothy D. Carbohydrate mouth rinse improves cycling time-trial performance without altering plasma insulin concentration. J Sports Sci Med. 2018;17:145–52.PubMedPubMedCentral

Title: The effect of carbohydrate mouth rinse on performance, biochemical and psychophysiological variables during a cycling time trial: a crossover randomized trial
Authors: Amanda M. J. Ferreira
Luiz F. Farias-Junior
Thaynan A. A. Mota
Hassan M. Elsangedy
Aline Marcadenti
Telma M. A. M. Lemos
Alexandre H. Okano
Ana P. T. Fayh
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of the International Society of Sports Nutrition / Issue 1/2018
Electronic ISSN: 1550-2783
DOI: https://doi.org/10.1186/s12970-018-0225-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The effect of carbohydrate mouth rinse on performance, biochemical and psychophysiological variables during a cycling time trial: a crossover randomized trial

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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