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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2018 | Technical notes

Cardiovascular cine imaging and flow evaluation using Fast Interrupted Steady-State (FISS) magnetic resonance

Authors: Robert R. Edelman, Ali Serhal, Amit Pursnani, Jianing Pang, Ioannis Koktzoglou

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2018

Abstract

Background

Existing cine imaging techniques rely on balanced steady-state free precession (bSSFP) or spoiled gradient-echo readouts, each of which has limitations. For instance, with bSSFP, artifacts occur from rapid through-plane flow and off-resonance effects. We hypothesized that a prototype cine technique, radial fast interrupted steady-state (FISS), could overcome these limitations. The technique was compared with standard cine bSSFP for cardiac function, coronary artery conspicuity, and aortic valve morphology. Given its advantageous properties, we further hypothesized that the cine FISS technique, in combination with arterial spin labeling (ASL), could provide an alternative to phase contrast for visualizing in-plane flow patterns within the aorta and branch vessels.

Main body

The study was IRB-approved and subjects provided consent. Breath-hold cine FISS and bSSFP were acquired using similar imaging parameters. There was no significant difference in biplane left ventricular ejection fraction or cardiac image quality between the two techniques. Compared with cine bSSFP, cine FISS demonstrated a marked decrease in fat signal which improved conspicuity of the coronary arteries, while suppression of through-plane flow artifact on thin-slice cine FISS images improved visualization of the aortic valve. Banding artifacts in the subcutaneous tissues were reduced. In healthy subjects, dynamic flow patterns were well visualized in the aorta, coronary and renal arteries using cine FISS ASL, even when the slice was substantially thicker than the vessel diameter.

Conclusion

Cine FISS demonstrates several benefits for cardiovascular imaging compared with cine bSSFP, including better suppression of fat signal and reduced artifacts from through-plane flow and off-resonance effects. The main drawback is a slight (~ 20%) decrease in temporal resolution. In addition, preliminary results suggest that cine FISS ASL provides a potential alternative to phase contrast techniques for in-plane flow quantification, while enabling an efficient, visually-appealing, semi-projective display of blood flow patterns throughout the course of an artery and its branches.

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Koktzoglou I, Edelman RR. Radial fast interrupted steady-state (FISS) magnetic resonance imaging. Magn Reson Med. 2017; https://doi.org/10.1002/mrm.26881. [Epub ahead of print]

Edelman RR, Giri S, Pursnani A, Botelho MPG, Li W, Koktzoglou I. Breath-hold imaging of the coronary arteries using quiescent-interval slice-selective (QISS) magnetic resonance angiography: pilot study at 1.5 Tesla and 3 Tesla. J Cardiovasc Magn Reson. 2015;17:101.CrossRefPubMedPubMedCentral

Scheffler K, Heid O, Hennig J. Magnetization preparation during the steady state: fat saturated 3D TrueFISP. Magn Reson Med. 2001;45:1075–80.CrossRefPubMed

Derbyshire JA, Herzka DA, McVeigh ER. S5FP: spectrally selective suppression with steady state free precession. Magn Reson Med. 2005;54:918–28.CrossRefPubMedPubMedCentral

Kato S, Kitagawa K, Ishida N, et al. Assessment of coronary artery disease using magnetic resonance coronary angiography: a national multicenter trial. J Am Coll Cardiol. 2010;56(12):983–91. https://doi.org/10.1016/j.jacc.2010.01.071.CrossRefPubMed

Markl M, Alley MT, Elkins CJ, Pelc JJ. Flow effects in balanced steady state free precession imaging. Magn Reson Med. 2003;50(5):892–903.CrossRefPubMed

Storey P, Li W, Chen Q, Edelman RR. Flow artifacts in steady-state free precession cine imaging. Magn Reson Med. 2004;51:115–22.CrossRefPubMed

Litmanovich DE, Ghersin E, Burke DA, Popma J, Shahrzad M, Bankier AA. Imaging in transcatheter aortic valve replacement (TAVR): role of the radiologist. Insights Imaging. 2014;5(1):123–45. https://doi.org/10.1007/s13244-013-0301-5. Epub 2014 Jan 21CrossRefPubMedPubMedCentral

Nayak KS, Nielsen J-F, Bernstein MA, et al. Cardiovascular magnetic resonance phase contrast imaging. J Cardiovasc Magn Reson. 2015;17:71. https://doi.org/10.1186/s12968-015-0172-7.CrossRefPubMedPubMedCentral

10.

Dixon WT, Du LN, Faul DD, Gado M, Rossnick S. Projection angiograms of blood labeled by adiabatic fast passage. Magn Reson Med. 1986;3:454–62.CrossRefPubMed

11.

Haller S, Zaharchuk G, Thomas DL, Lovblad K-O, Barkhof F, Golay X. Arterial spin labeling perfusion of the brain: emerging clinical applications. Radiology. 2016;281:337–56.CrossRefPubMed

12.

Edelman RR, Siewert B, Adamis M, Gaa J, Laub G, Wiepolski P. Signal targeting with alternating radiofrequency (STAR) sequences: application to MR angiography. Magn Reson Med. 1994;31(22):233–8.CrossRefPubMed

13.

Xu J, Shi D, Chen C, et al. Noncontrast-enhanced four-dimensional MR angiography for the evaluation of cerebral arteriovenous malformation: a preliminary trial. J Magn Reson Imaging. 2011;34:1199–205.CrossRefPubMed

14.

Iryo Y, Hirai T, Nakamura M, et al. Collateral circulation via the circle of Willis in patients with carotid artery steno-occlusive disease: evaluation on 3-T 4D MRA using arterial spin labeling. Clin Radiol. 2015;70:960–5.CrossRefPubMed

15.

Okell TW, Schmitt P, Bi X, et al. Optimization of 4D vessel-selective arterial spin labeling angiography using balanced steady-state free precession and vessel-encoding. NMR Biomed. 2016;29(6):776–86. https://doi.org/10.1002/nbm.3515.CrossRefPubMedPubMedCentral

16.

Mattle H, Edelman RR, Reis MA, Atkinson DJ. Flow quantification in the superior sagittal sinus using magnetic resonance. Neurology. 1990;40(5):813–5.CrossRefPubMed

17.

Bernstein M, King K, Zhou J. Handbook of MRI. Pulse sequences. London: Elsevier Press; 2004.

18.

Yang AC, Kretzler M, Sudarski S, Gulani V, Seiberlich N. Sparse reconstruction techniques in magnetic resonance imaging: methods, applications, and challenges to clinical adoption. Investig Radiol. 2016;51(6):349–64. https://doi.org/10.1097/RLI.0000000000000274.CrossRef

Title: Cardiovascular cine imaging and flow evaluation using Fast Interrupted Steady-State (FISS) magnetic resonance
Authors: Robert R. Edelman
Ali Serhal
Amit Pursnani
Jianing Pang
Ioannis Koktzoglou
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue 1/2018
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/s12968-018-0433-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Cardiovascular cine imaging and flow evaluation using Fast Interrupted Steady-State (FISS) magnetic resonance

Abstract

Background

Main body

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Main body

Conclusion

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