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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2015 | Study protocol

UK Biobank’s cardiovascular magnetic resonance protocol

Authors: Steffen E. Petersen, Paul M. Matthews, Jane M. Francis, Matthew D. Robson, Filip Zemrak, Redha Boubertakh, Alistair A. Young, Sarah Hudson, Peter Weale, Steve Garratt, Rory Collins, Stefan Piechnik, Stefan Neubauer

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2017

Abstract

Background

UK Biobank’s ambitious aim is to perform cardiovascular magnetic resonance (CMR) in 100,000 people previously recruited into this prospective cohort study of half a million 40-69 year-olds.

Methods/design

We describe the CMR protocol applied in UK Biobank’s pilot phase, which will be extended into the main phase with three centres using the same equipment and protocols. The CMR protocol includes white blood CMR (sagittal anatomy, coronary and transverse anatomy), cine CMR (long axis cines, short axis cines of the ventricles, coronal LVOT cine), strain CMR (tagging), flow CMR (aortic valve flow) and parametric CMR (native T1 map).

Discussion

This report will serve as a reference to researchers intending to use the UK Biobank resource or to replicate the UK Biobank cardiovascular magnetic resonance protocol in different settings.

Petersen SE, Matthews PM, Bamberg F, Bluemke DA, Francis JM, Friedrich MG, et al. Imaging in population science: cardiovascular magnetic resonance in 100,000 participants of UK Biobank - rationale, challenges and approaches. J Cardiovasc Magn Reson. 2013;15:46.CrossRefPubMedCentralPubMed

O'Rourke MF. Influence of ventricular ejection on the relationship between central aortic and brachial pressure pulse in man. Cardiovasc Res. 1970;4:291–300.CrossRefPubMed

Rider OJ, Holloway CJ, Emmanuel Y, Bloch E, Clarke K, Neubauer S. Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity. Circ Cardiovasc Imaging. 2012;5:367–75.CrossRefPubMed

Kilner PJ, Gatehouse PD, Firmin DN. Flow measurement by magnetic resonance: a unique asset worth optimising. J Cardiovasc Magn Reson. 2007;9:723–8.CrossRefPubMed

Title: UK Biobank’s cardiovascular magnetic resonance protocol
Authors: Steffen E. Petersen
Paul M. Matthews
Jane M. Francis
Matthew D. Robson
Filip Zemrak
Redha Boubertakh
Alistair A. Young
Sarah Hudson
Peter Weale
Steve Garratt
Rory Collins
Stefan Piechnik
Stefan Neubauer
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue 1/2017
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/s12968-016-0227-4

ACC 2024 Congress

Springer Medicine

UK Biobank’s cardiovascular magnetic resonance protocol

Abstract

Background

Methods/design

Discussion

ACC 2024 Congress

Springer Medicine

Abstract

Background

Methods/design

Discussion

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