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Health Research Policy and Systems
Published in: Health Research Policy and Systems 1/2017

Open Access 01-12-2017 | Research

Global toxocariasis research trends from 1932 to 2015: a bibliometric analysis

Author: Sa’ed H. Zyoud

Published in: Health Research Policy and Systems | Issue 1/2017

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Abstract

Background

Toxocariasis is a highly prevalent parasitic disease in the tropical regions of the world, with its impact on public health being typically underestimated. To better recognise the trends and characteristics of toxocariasis research, this study is a bibliometric analysis of the global toxocariasis research.

Methods

Searches were completed on April 5, 2016, using the Scopus database. A search without any language restriction was performed to extract publications dealing with toxocariasis. Terms related to toxocariasis were used to perform a title keyword search.

Results

A total of 2765 publications comprising 11 document types and published between 1932 and 2015 were included in the analysis. Articles were the most popular document form, accounting for 83.62% of all publications, followed by letters (3.80%) and reviews (3.4%). The annual number of research publications increased from 30 in 1980 to 111 in 2015, indicating that the number of publications on toxocariasis has increased slowly over the past 35 years. The United States of America and Japan are the predominant countries of origin, with 303 articles and 207 articles, respectively, followed by Brazil and the United Kingdom, with 180 (6.5%) each. The h-index for all the publications was 60. The highest h-index were for publications from the United Kingdom (h-index value = 43) and the United States (h-index value = 39); these two countries were also involved with the highest number of international collaborations, with 27 and 28 countries, respectively.

Conclusions

Developed countries, including the United States, Japan, the United Kingdom, France, Germany and Italy, are the world’s leaders in toxocariasis research, contributing to more than 34% of the total published literature. In addition, developing countries, such as Brazil, Poland, Argentina and India, showed a noticeable increase in published papers on toxocariasis research in recent years. A push for more collaboration is needed to achieve a superior research strategy related to toxocariasis at the global level from the viewpoint of epidemiological data, clinical aspects, medical ecology, molecular aspects and treatment practices associated with toxocariasis.
Literature
1.
Moreira GM, Telmo Pde L, Mendonca M, Moreira AN, McBride AJ, Scaini CJ, Conceicao FR. Human toxocariasis: current advances in diagnostics, treatment, and interventions. Trends Parasitol. 2014;30:456–64.CrossRefPubMed
2.
Smith H, Holland C, Taylor M, Magnaval JF, Schantz P, Maizels R. How common is human toxocariasis? Towards standardizing our knowledge. Trends Parasitol. 2009;25:182–8.CrossRefPubMed
3.
Holland CV. Knowledge gaps in the epidemiology of Toxocara: the enigma remains. Parasitology. 2017;144(1):81–94.CrossRefPubMed
4.
Macpherson CN. The epidemiology and public health importance of toxocariasis: a zoonosis of global importance. Int J Parasitol. 2013;43:999–1008.CrossRefPubMed
5.
Nicoletti A. Toxocariasis. In: Garcia HH, Tanowitz HB, Del Brutto OH, editors. Neuroparasitology and Tropical Neurology, Handb Clin Neurol, vol. 114. 2013. p. 217–28.CrossRef
6.
Kuenzli E, Neumayr A, Chaney M, Blum J. Toxocariasis-associated cardiac diseases – A systematic review of the literature. Acta Trop. 2016;154:107–20.CrossRefPubMed
7.
Gavignet B, Piarroux R, Aubin F, Millon L, Humbert P. Cutaneous manifestations of human toxocariasis. J Am Acad Dermatol. 2008;59:1031–42.CrossRefPubMed
8.
Van Den Broucke S, Kanobana K, Polman K, Soentjens P, Vekemans M, Theunissen C, Vlieghe E, Van Esbroeck M, Jacobs J, Van Den Enden E, et al. Toxocariasis diagnosed in international travelers at the Institute of Tropical Medicine, Antwerp, Belgium, from 2000 to 2013. PLoS Negl Trop Dis. 2015;9:e0003559.CrossRef
9.
Cong W, Zhang XX, Zhou N, Yu CZ, Chen J, Wang XY, Li B, Qian AD, Zhu XQ. Toxocara seroprevalence among clinically healthy individuals, pregnant women and psychiatric patients and associated risk factors in Shandong Province, Eastern China. PLoS Negl Trop Dis. 2014;8:e3082.CrossRefPubMedPubMedCentral
10.
Janecek E, Wilk E, Schughart K, Geffers R, Strube C. Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes. Int J Parasitol. 2015;45:495–503.CrossRefPubMed
11.
de Almeida Carvalho EA, Rocha RL. Visceral larva migrans syndromes associated with toxocariasis: epidemiology, clinical and laboratory aspects of human toxocariasis. Curr Trop Med Rep. 2014;1:74–9.CrossRef
12.
Patino-Barbosa AM, Bedoya-Arias JE, Cardona-Ospina JA, Rodriguez-Morales AJ. Bibliometric assessment of the scientific production of literature regarding Mayaro. J Infect Public Health. 2016;9:532–4.CrossRefPubMed
13.
Martinez-Pulgarin DF, Acevedo-Mendoza WF, Cardona-Ospina JA, Rodriguez-Morales AJ, Paniz-Mondolfi AE. A bibliometric analysis of global Zika research. Travel Med Infect Dis. 2016;14:55–7.CrossRefPubMed
14.
Vera-Polania F, Munoz-Urbano M, Banol-Giraldo AM, Jimenez-Rincon M, Granados-Alvarez S, Rodriguez-Morales AJ. Bibliometric assessment of scientific production of literature on chikungunya. J Infect Public Health. 2015;8:386–8.CrossRefPubMed
15.
16.
Fu H, Hu T, Wang J, Feng D, Fang H, Wang M, Tang S, Yuan F, Feng Z. A bibliometric analysis of malaria research in China during 2004–2014. Malar J. 2015;14:195.CrossRefPubMedPubMedCentral
17.
Sweileh WM, Sawalha AF, Al-Jabi SW, Zyoud SH, Shraim NY, Abu-Taha AS. A bibliometric analysis of literature on malaria vector resistance: (1996–2015). Glob Health. 2016;12:76.CrossRef
18.
Vera-Polania F, Perilla-Gonzalez Y, Martinez-Pulgarin DF, Baquero-Rodriguez JD, Munoz-Urbano M, Lagos-Gallego M, Lagos-Grisales GJ, Villegas S, Rodriguez-Morales AJ. Bibliometric assessment of the Latin-American contributions in dengue. Recent Pat Antiinfect Drug Discov. 2014;9:195–201.CrossRefPubMed
19.
20.
Yi F, Yang P, Sheng H. Tracing the scientific outputs in the field of Ebola research based on publications in the Web of Science. BMC Res Notes. 2016;9:221.CrossRefPubMedPubMedCentral
21.
22.
Escobedo AA, Arencibia R, Vega RL, Rodriguez-Morales AJ, Almirall P, Alfonso M. A bibliometric study of international scientific productivity in giardiasis covering the period 1971–2010. J Infect Dev Ctries. 2015;9:76–86.CrossRefPubMed
23.
Zyoud SH, Al-Jabi SW, Sweileh WM. Worldwide research productivity in the field of electronic cigarette: a bibliometric analysis. BMC Public Health. 2014;14:667.CrossRefPubMedPubMedCentral
24.
Zyoud SH, Al-Jabi SW, Sweileh WM, Awang R. A Scopus-based examination of tobacco use publications in Middle Eastern Arab countries during the period 2003–2012. Harm Reduct J. 2014;11:14.CrossRefPubMedPubMedCentral
25.
Sweileh WM, Al-Jabi SW, Sawalha AF, AbuTaha AS, Zyoud SH. Bibliometric analysis of publications on Campylobacter: (2000–2015). J Health Popul Nutr. 2016;35:39.CrossRefPubMedPubMedCentral
26.
Zyoud SH, Al-Jabi SW, Sweileh WM, Awang R, Waring WS. Global research productivity of N-acetylcysteine use in paracetamol overdose: a bibliometric analysis (1976–2012). Hum Exp Toxicol. 2015;34:1006–16.CrossRefPubMed
27.
Zyoud SH, Al-Jabi SW, Sweileh WM, Al-Khalil S, Alqub M, Awang R. Global methaemoglobinaemia research output (1940–2013): a bibliometric analysis. Springerplus. 2015;4:626.CrossRefPubMedPubMedCentral
28.
Falagas ME, Pitsouni EI, Malietzis GA, Pappas G. Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses. FASEB J. 2008;22:338–42.CrossRefPubMed
29.
30.
Quattrocchi G, Nicoletti A, Marin B, Bruno E, Druet-Cabanac M, Preux PM. Toxocariasis and epilepsy: systematic review and meta-analysis. PLoS Negl Trop Dis. 2012;6:e1775.CrossRefPubMedPubMedCentral
31.
Fialho PM, Correa CR. A systematic review of toxocariasis: a neglected but high-prevalence disease in Brazil. Am J Trop Med Hyg. 2016;94:1193–9.CrossRefPubMed
32.
Thomson Reuters: 2014 Journal Citation Reports®. 2015. http://​www.​isiknowledge.​com.​ Accessed 13 Nov 2015.
33.
Barriga OO. A critical look at the importance, prevalence and control of toxocariasis and the possibilities of immunological control. Vet Parasitol. 1988;29:195–234.CrossRefPubMed
34.
Beaver PC, Snyder CH, Carrera GM, Dent JH, Lafferty JW. Chronic eosinophilia due to visceral larva migrans; report of three cases. Pediatrics. 1952;9:7–19.PubMed
35.
De Savigny DH. In vitro maintenance of Toxocara canis larvae and a simple method for the production of Toxocara ES antigen for use in serodiagnostic tests for visceral larva migrans. J Parasitol. 1975;61:781–2.CrossRefPubMed
36.
37.
Del Prete GF, De Carli M, Mastromauro C, Biagiotti R, Macchia D, Falagiani P, Ricci M, Romagnani S. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J Clin Invest. 1991;88:346–50.CrossRefPubMedPubMedCentral
38.
39.
40.
Glickman L, Schantz P, Dombroske R, Cypess R. Evaluation of serodiagnostic tests for visceral larva migrans. Am J Trop Med Hyg. 1978;27:492–8.PubMed
41.
Glickman LT, Schantz PM. Epidemiology and pathogenesis of zoonotic toxocariasis. Epidemiol Rev. 1981;3:230–50.CrossRefPubMed
42.
Jacquier P, Gottstein B, Stingelin Y, Eckert J. Immunodiagnosis of toxocarosis in humans: evaluation of a new enzyme-linked immunosorbent assay kit. J Clin Microbiol. 1991;29:1831–5.PubMedPubMedCentral
43.
Magnaval JF, Fabre R, Maurieres P, Charlet JP, de Larrard B. Application of the western blotting procedure for the immunodiagnosis of human toxocariasis. Parasitol Res. 1991;77:697–702.CrossRefPubMed
44.
45.
Maizels RM, de Savigny D, Ogilvie BM. Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae. Parasite Immunol. 1984;6:23–37.CrossRefPubMed
46.
Overgaauw PA. Aspects of Toxocara epidemiology: human toxocarosis. Crit Rev Microbiol. 1997;23:215–31.CrossRefPubMed
47.
Overgaauw PA. Aspects of Toxocara epidemiology: toxocarosis in dogs and cats. Crit Rev Microbiol. 1997;23:233–51.CrossRefPubMed
48.
Rubinsky-Elefant G, Hirata CE, Yamamoto JH, Ferreira MU. Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms. Ann Trop Med Parasitol. 2010;104:3–23.CrossRefPubMed
49.
Schantz PM. Toxocara larva migrans now. Am J Trop Med Hyg. 1989;41:21–34.PubMed
50.
51.
Taylor MR, Keane CT, O’Connor P, Mulvihill E, Holland C. The expanded spectrum of toxocaral disease. Lancet. 1988;1:692–5.CrossRefPubMed
52.
Wilder HC. Nematode endophthalmitis. Trans Am Acad Ophthalmol Otolaryngol. 1950;55:99–109.PubMed
53.
Munoz-Urbano M, Lopez-Isaza AF, Hurtado-Hurtado N, Gomez-Suta D, Murillo-Abadia J, Delgado-Osorio N, Lagos-Grisales GJ, Villegas S, Medina-Morales DA, Rodriguez-Morales AJ. Scientific research in malaria: bibliometric assessment of the Latin-American contributions. Recent Pat Antiinfect Drug Discov. 2014;9:209–15.CrossRefPubMed
54.
Gonzalez-Alcaide G, Park J, Huamani C, Gascon J, Ramos JM. Scientific authorships and collaboration network analysis on Chagas disease: papers indexed in PubMed (1940–2009). Rev Inst Med Trop Sao Paulo. 2012;54:219–28.CrossRefPubMed
55.
Peng Y, Lin A, Wang K, Liu F, Zeng F, Yang L. Global trends in DEM-related research from 1994 to 2013: a bibliometric analysis. Scientometrics. 2015;105:347–66.CrossRef
56.
Zhang L, Wang M-H, Hu J, Ho Y-S. A review of published wetland research, 1991–2008: ecological engineering and ecosystem restoration. Ecol Eng. 2010;36:973–80.CrossRef
57.
Liu X, Zhang L, Hong S. Global biodiversity research during 1900–2009: a bibliometric analysis. Biodivers Conserv. 2011;20:807–26.CrossRef
58.
Borecka A, Klapec T. Epidemiology of human toxocariasis in Poland – A review of cases 1978–2009. Ann Agric Environ Med. 2015;22:28–31.CrossRefPubMed
59.
Martin UO, Demonte MA. Urban contamination with zoonotic parasites in the central region of Argentina. Medicina (B Aires). 2008;68:363–6.
60.
Ahmad B, Bhatti G, Thokar MA, Malla N. Human toxocariasis and ascariasis: concomitant parasitism in Srinagar, Kashmir, India. Indian J Pathol Microbiol. 2002;45:315–8.PubMed
61.
Li T, Ho YS, Li CY. Bibliometric analysis on global Parkinson’s disease research trends during 1991–2006. Neurosci Lett. 2008;441:248–52.CrossRefPubMed
62.
Zyoud SH, Al-Jabi SW, Sweileh WM, Awang R, Waring WS. Bibliometric profile of the global scientific research on methanol poisoning (1902–2012). J Occup Med Toxicol. 2015;10:17.CrossRefPubMedPubMedCentral
63.
Zyoud SH. Bibliometric analysis on global Catha edulis (khat) research production during the period of 1952–2014. Glob Health. 2015;11:39.CrossRef
64.
Zyoud SH, Al-Jabi SW, Sweileh WM, Al-Khalil S, Zyoud SH, Sawalha AF, Awang R. The Arab world’s contribution to solid waste literature: a bibliometric analysis. J Occup Med Toxicol. 2015;10:35.CrossRefPubMedPubMedCentral
Metadata
Title
Global toxocariasis research trends from 1932 to 2015: a bibliometric analysis
Author
Sa’ed H. Zyoud
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Health Research Policy and Systems / Issue 1/2017
Electronic ISSN: 1478-4505
DOI
https://doi.org/10.1186/s12961-017-0178-8

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