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Open Access 01-12-2019 | Research

Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies

Authors: Kristina Geue, Heide Götze, Michael Friedrich, Katja Leuteritz, Anja Mehnert-Theuerkauf, Annekathrin Sender, Yve Stöbel-Richter, Norbert Köhler

Published in: Health and Quality of Life Outcomes | Issue 1/2019

Abstract

Background

This study compared the perceived social support of young and older adult cancer patients, examining possible influencing factors as well as associations with health-related quality of life.

Methods

A total of 179 young patients (18–39 years) and 200 older adult patients (> 70 years) with haematological malignancies completed questionnaires on their perceived social support (ISSS-8, scales: Positive Support and Detrimental Interactions, range 0–16) and health-related quality of life (EORTC QLQ-C30). Tests for mean differences, correlations and regression analyses to determine associated variables of social support were performed.

Results

No difference was reported between young (M = 13.40, SD = 2.81) and older adult patients (M = 13.04, SD = 3.82; p = .313) for Positive Support. However, young patients (M = 4.16, SD = 3.10) reported having had more Detrimental Interactions than older patients did (M = 1.63, SD = 2.42; p < .001, Cohen’s d = .910). Comparison of the EORTC QLQ-C30 Function scales showed poorer outcomes for young patients on Emotional, Cognitive and Social Functions and a higher outcome on Physical Function compared with older adult patients. Regression analyses indicated that age (young vs. older adult patients) significantly explained proportions of variance in all models, with young age having a negative impact on Emotional, Cognitive and Social Functions and a positive impact on Physical and Role Functions compared with old age. Significant associations between Detrimental Interactions and all the scales examined except Cognitive Function were found.

Conclusions

The difference in negative perceptions of social support in young vs. older adult patients and its impact on health-related quality of life emphasises the necessity of differentiating between positive and negative social support. Negative interactions should be addressed through psychosocial care, particularly with young cancer patients.

Rodriguez-Abreu D, Bordoni A, Zucca E. Epidemiology of hematological malignancies. Ann Oncol. 2007;18(Suppl 1):i3–8. https://doi.org/10.1093/annonc/mdl443.CrossRefPubMed

Sant M, Allemani C, Tereanu C. HAEMACARE working group. Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project (vol 116, pg 3724, 2010). BLOOD. 2011;117(12):3477. https://doi.org/10.1182/blood-2011-02-335794.CrossRef

Hilgendorf I, Borchmann P, Engel J, Heußner P, Katalinic A, Neubauer A, Rahimi G, Willenbacher W, Wörmann BJ (2016) Heranwachsende und junge Erwachsene: Onkopedia Leitlinien. https://www.onkopedia.com/de/my-onkopedia/guidelines/heranwachsende-und-junge-erwachsene-aya/@@guideline/html/index.html#ID0ER.

Adolescent and Young Adult Oncology Progress Review Group, 2006. Closing the Gap. Research and Care Imperatives for Adolescents and Young Adults with Cancer. Edited by U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES (NIH Publication No. 06–6067).

Bleyer A, Barr R, Hayes-Lattin B, et al. The distinctive biology of cancer in adolescents and young adults. Nature reviews. Cancer. 2008;8(4):288–98. https://doi.org/10.1038/nrc2349.CrossRefPubMed

Hilgendorf I, Freund M, Kropp P, et al. Oncological diseases in adolescence and young adults - data from the clinical Cancer registry Rostock as a basis for a interdisciplinary challenge. Tumor Diagnostik und Therapie. 2011;32(32):85–92. https://doi.org/10.1055/s-0029-1246000.CrossRef

Brandstätter J, Lindenberger U, editors. Entwicklungspsychologie der Lebensspanne. 1. Auflage ed. Kohlhammer: Stuttgart; 2007.

Zebrack BJ. Psychological, social, and behavioral issues for young adults with cancer. Cancer. 2011;117(10 Suppl):2289–94. https://doi.org/10.1002/cncr.26056.CrossRefPubMed

Weiss Wiesel TR, Nelson CJ, Tew WP, et al. The relationship between age, anxiety, and depression in older adults with cancer. Psycho-oncology. 2015;24(6):712–7. https://doi.org/10.1002/pon.3638.CrossRefPubMed

10.

Pashos CL, Flowers CR, Kay NE, et al. Association of health-related quality of life with gender in patients with B-cell chronic lymphocytic leukemia. Support Care Cancer. 2013;21(10):2853–60. https://doi.org/10.1007/s00520-013-1854-z.CrossRefPubMed

11.

Hurria A, Li D, Hansen K, et al. Distress in older patients with cancer. J Clin Oncol. 2009;27(26):4346–51. https://doi.org/10.1200/JCO.2008.19.9463.CrossRefPubMedPubMedCentral

12.

Hinz A, Singer S, Brähler E. European reference values for the quality of life questionnaire EORTC QLQ-C30: results of a German investigation and a summarizing analysis of six European general population normative studies. Acta Oncol. 2014;53:958–65. https://doi.org/10.3109/0284186X.2013.879998.CrossRefPubMed

13.

Hall AE, Boyes AW, Bowman J, et al. Young adult cancer survivors' psychosocial well-being: a cross-sectional study assessing quality of life, unmet needs, and health behaviors. Support Care Cancer. 2012;20(6):1333–41. https://doi.org/10.1007/s00520-011-1221-x.CrossRefPubMed

14.

Drost FM, Mols F, Kaal SEJ, et al. Psychological impact of lymphoma on adolescents and young adults: not a matter of black or white. Journal of cancer survivorship: research and practice. 2016;10(4):726–35. https://doi.org/10.1007/s11764-016-0518-7.CrossRef

15.

Winzer A, Hoppe A, Altenhoff J, et al. Interest in a psycho-educational group intervention among out-patients with malignant melanoma in relation to their need: which patients are likely to participate? Psycho-oncology. 2009;18(11):1179–88. https://doi.org/10.1002/pon.1164.CrossRefPubMed

16.

Dirksen SR. Predicting well-being among breast cancer survivors. J Adv Nurs. 2000;32(4):937–43. https://doi.org/10.1046/j.1365-2648.2000.01559.x.CrossRefPubMed

17.

Flanagan J, Holmes S. Social perceptions of cancer and their impacts. J Adv Nurs. 2000;32(3):740–9. https://doi.org/10.1046/j.1365-2648.2000.01535.x.CrossRefPubMed

18.

Mattioli JL, Repinski R, Chappy SL. The meaning of hope and social support in patients receiving chemotherapy. Oncol Nurs Forum. 2008;35(5):822–9. https://doi.org/10.1188/08.ONF.822-829.CrossRefPubMed

19.

Gonzalez-Saenz de Tejada M, Bilbao A, Baré M, et al. Association between social support, functional status, and change in health-related quality of life and changes in anxiety and depression in colorectal cancer patients. Psycho-oncology. 2017;26(9):1263–9. https://doi.org/10.1002/pon.4303.CrossRefPubMed

20.

Yoo H, Shin DW, Jeong A, et al. Perceived social support and its impact on depression and health-related quality of life: a comparison between cancer patients and general population. Jpn J Clin Oncol. 2017;47(8):728–34. https://doi.org/10.1093/jjco/hyx064.CrossRefPubMed

21.

Lincoln KD. Social support, negative social interactions, and psychological well-being. Soc Serv Rev. 2000;74(2):231–52. https://doi.org/10.1086/514478.CrossRefPubMedPubMedCentral

22.

Leung J, Pachana NA, McLaughlin D. Social support and health-related quality of life in women with breast cancer: a longitudinal study. Psycho-oncology. 2014;23(9):1014–20. https://doi.org/10.1002/pon.3523.CrossRefPubMed

23.

Schulz U, Schwarzer R. Social support in coping with illness: the Berlin social support scales (BSSS). Diagnostica. 2003;49(2):73–82. https://doi.org/10.1026//0012-1924.49.2.73.CrossRef

24.

Corey AL, Haase JE, Azzouz F, et al. Social support and symptom distress in adolescents/young adults with cancer. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. 2008;25(5):275–84. https://doi.org/10.1177/1043454208321117.CrossRef

25.

Kyngas H, Mikkonen R, Nousiainen E, et al. Coping with the onset of cancer. Eur J Cancer Care. 2001;10(1):6–11. https://doi.org/10.1046/j.1365-2354.2001.00243.x.CrossRef

26.

Leuteritz K, Friedrich M, Nowe E, et al. Life situation and psychosocial care of adolescent and young adult (AYA) cancer patients - study protocol of a 12-month prospective longitudinal study. BMC Cancer. 2017;17(1):82. https://doi.org/10.1186/s12885-017-3077-z.CrossRefPubMedPubMedCentral

27.

Buske C, Hiddemann W. Der ältere Patient mit malignen Erkrankungen. Internist. 2007;48(11):1206–10. https://doi.org/10.1007/s00108-007-1955-1.CrossRefPubMed

28.

Köhler N, Mehnert A, Götze H. Psychological distress, chronic conditions and quality of life in elderly hematologic cancer patients: study protocol of a prospective study. BMC Cancer. 2017;17(1):700. https://doi.org/10.1186/s12885-017-3662-1.CrossRefPubMedPubMedCentral

29.

Ramm GC, Hasenbring M (2003) Die deutsche Adaptation der Illness-specific Social Support Scale und ihre teststatistische Überprüfung beim Einsatz an Patienten vor und nach Knochenmarktransplantation. Zeitschrift für Medizinische Psychologie 12((1)): 29–38.

30.

Revenson TA, Schiaffino KM, Deborah Majerovitz S, Gibofsky A. Social support as a double-edged sword: the relation of positive and problematic support to depression among rheumatoid arthritis patients. Soc Sci Med. 1991;33(7):807–913.CrossRef

31.

Ullrich A, Mehnert A. Psychometrische Evaluation and Validierung einer 8-Item Kurzversion der Skalen zur Sozialen Unterstützung bei Krankheit (SSUK) bei Krebspatienten. Klinische Diagnostik und Evaluation. 2010;3:359–81.

32.

Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365–76.CrossRef

33.

Cocks K, King MT, Velikova G, et al. Evidence-based guidelines for determination of sample size and interpretation of the European organisation for the research and treatment of Cancer quality of life questionnaire Core 30. J Clin Oncol. 2011;29(1):89–96. https://doi.org/10.1200/JCO.2010.28.0107.CrossRefPubMed

34.

Hann D, Baker F, Denniston M, et al. The influence of social support on depressive symptoms in cancer patients - age and gender differences. J Psychosom Res. 2002;52(5):279–83.CrossRef

35.

Pinquart M, Höffken K, Silbereisen RK, et al. Social support and survival in patients with acute myeloid leukaemia. Support Care Cancer. 2007;15(1):81–7. https://doi.org/10.1007/s00520-006-0114-x.CrossRefPubMed

36.

Soares A, Biasoli I, Scheliga A, et al. Association of social network and social support with health-related quality of life and fatigue in long-term survivors of Hodgkin lymphoma. Support Care Cancer. 2013;21(8):2153–9. https://doi.org/10.1007/s00520-013-1775-x.CrossRefPubMed

37.

Pailler ME, Johnson TM, Kuszczak S, et al. Adjustment to acute leukemia: the impact of social support and marital satisfaction on distress and quality of life among newly diagnosed patients and their caregivers. J Clin Psychol Med Settings. 2016;23(3):298–309. https://doi.org/10.1007/s10880-016-9459-6.CrossRefPubMed

38.

Due P, Holstein B, Lund R, Modvig J, Avlund K. Social relations: network, support and relational strain. Soc Sci Med. 1999;48:661–73.CrossRef

39.

Blank TO, Bellizzi KM. A gerontologic perspective on cancer and aging. Cancer. 2008;112(11 Suppl):2569–76. https://doi.org/10.1002/cncr.23444.CrossRefPubMed

40.

Guy GP, Ekwueme DU, Yabroff KR, Dowling EC, Li C, Rodriguez JL, et al. Economic burden of cancer survivorship among adults in the United States. J Clin Oncol. 2013;31(30):3749–57. https://doi.org/10.1200/JCO.2013.49.1241.CrossRefPubMedPubMedCentral

41.

Geue K, Sender A, Schmidt R, Richter D, Hinz A, Schulte T, Brähler E, Stöbel-Richter Y. Gender-specific quality of life after cancer in young adulthood: a comparison with the general population. Qual Life Res. 2014;23(4):1377–86. https://doi.org/10.1007/s11136-013-0559-6.CrossRefPubMed

42.

Costa ALS, Heitkemper MM, Alencar GP, et al. Social support is a predictor of lower stress and higher quality of life and resilience in Brazilian patients with colorectal Cancer. Cancer Nurs. 2017;40(5):352–60. https://doi.org/10.1097/NCC.0000000000000388.CrossRef

43.

Breuer N, Sender A, Daneck L, et al. How do young adults with cancer perceive social support? A qualitative study. J Psychosoc Oncol. 2017;35(3):292–308. https://doi.org/10.1080/07347332.2017.1289290.CrossRefPubMed

Title: Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies
Authors: Kristina Geue
Heide Götze
Michael Friedrich
Katja Leuteritz
Anja Mehnert-Theuerkauf
Annekathrin Sender
Yve Stöbel-Richter
Norbert Köhler
Publication date: 01-12-2019
Publisher: BioMed Central
Published in: Health and Quality of Life Outcomes / Issue 1/2019
Electronic ISSN: 1477-7525
DOI: https://doi.org/10.1186/s12955-019-1202-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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