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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2019

Open Access 01-12-2019 | Breast Cancer | Research

The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial

Authors: Thais R. S. Paulo, Fabricio E. Rossi, Juliana Viezel, Giuliano T. Tosello, Sylvia C. Seidinger, Regina R. Simões, Ruffo de Freitas Jr, Ismael F. Freitas Jr

Published in: Health and Quality of Life Outcomes | Issue 1/2019

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Abstract

Background

This study evaluated the impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.

Methods

Older breast cancer survivors were randomized into two groups: combined training: resistance + aerobic exercise program for nine months (n = 18) or control group (n = 18). Quality of life was assessed by the questionnaires SF36, EORTC QLQ-C30, and EORTC QLQ-BR23 at baseline, and at three, six, and nine months. The exercise group performed 40 min of resistance exercises on machines followed by 30 min of aerobic training on a treadmill 3x/wk. Repeated measures ANOVA was used to compare the groups over time.

Results

Significant time x group interactions and moderate to high effect sizes were found for physical functioning, physical health, bodily pain, general health perception, vitality, social functioning, fatigue, sleep disturbance, body image, and upset by hair loss, favoring the exercise group.

Conclusion

This study demonstrated the potential benefits and high clinical relevance of exercise programs to improve quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.
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Metadata
Title
The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial
Authors
Thais R. S. Paulo
Fabricio E. Rossi
Juliana Viezel
Giuliano T. Tosello
Sylvia C. Seidinger
Regina R. Simões
Ruffo de Freitas Jr
Ismael F. Freitas Jr
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2019
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-019-1090-4

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