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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2015

Open Access 01-12-2015 | Research

Cross-cultural adaptation, reliability and validity of the Spanish version of the Quality of Life in Adult Cancer Survivors (QLACS) questionnaire: application in a sample of short-term survivors

Authors: Antonio Escobar, Maria del Mar Trujillo-Martín, Antonio Rueda, Elisabeth Pérez-Ruiz, Nancy E. Avis, Amaia Bilbao

Published in: Health and Quality of Life Outcomes | Issue 1/2015

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Abstract

Background

The aim of this study was to validate the Quality of Life in Adult Cancer Survivors (QLACS) in short-term Spanish cancer survivor’s patients.

Methods

Patients with breast, colorectal or prostate cancer that had finished their initial cancer treatment 3 years before the beginning of this study completed QLACS, WHOQOL, Short Form-36, Hospital Anxiety and Depression Scale, EORTC-QLQ-BR23 and EQ-5D. Cultural adaptation was made based on established guidelines. Reliability was evaluated using internal consistency and test-retest. Convergent validity was studied by mean of Pearson’s correlation coefficient. Structural validity was determined by a second-order confirmatory factor analysis (CFA) and Rasch analysis was used to assess the unidimensionality of the Generic and Cancer-specific scales.

Results

Cronbach’s alpha were above 0.7 in all domains and summary scales. Test-retest coefficients were 0.88 for Generic and 0.82 for Cancer-specific summary scales.
QLACS generic summary scale was correlated with other generic criterion measures, SF-36 MCS (r = − 0.74) and EQ-VAS (r = − 0.63). QLACS cancer-specific scale had lower values with the same constructs.
CFA provided satisfactory fit indices in all cases. The RMSEA value was 0.061 and CFI and TLI values were 0.929 and 0.925, respectively. All factor loadings were higher than 0.40 and statistically significant (P < 0.001). Generic summary scale had eight misfitting items. In the remaining 20 items, the unidimensionality was supported. Cancer Specific summary scale showed four misfitting items, the remaining showed unidimensionality.

Conclusions

The findings support the validity and reliability of QLACS questionnaire to be used in short-term cancer survivors.
Appendix
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Metadata
Title
Cross-cultural adaptation, reliability and validity of the Spanish version of the Quality of Life in Adult Cancer Survivors (QLACS) questionnaire: application in a sample of short-term survivors
Authors
Antonio Escobar
Maria del Mar Trujillo-Martín
Antonio Rueda
Elisabeth Pérez-Ruiz
Nancy E. Avis
Amaia Bilbao
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2015
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-015-0378-2

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