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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2014

Open Access 01-12-2014 | Research

Osteoarthritis medical labelling and health-related quality of life in the general population

Authors: Sara Lourenço, Raquel Lucas, Fábio Araújo, Mónica Bogas, Rui André Santos, Henrique Barros

Published in: Health and Quality of Life Outcomes | Issue 1/2014

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Abstract

Background

Osteoarthritis is the most common chronic joint disease. In the absence of an effective medical treatment and due to the chronic nature of this condition, an osteoarthritis medical diagnosis may finally result in decreased health-related quality of life. Therefore, the aim of this study was to measure the impact of the osteoarthritis medical labelling on physical and mental health-related quality of life.

Methods

Subjects (n = 1132, 58.7% women) were approached as participants of an urban population-based cohort (EPIPorto). Self-reported information on previous diagnosis of knee, hip or hand osteoarthritis was obtained and rheumatologists established knee, hip or hand osteoarthritis clinical diagnosis in symptomatic individuals. Physical and mental dimensions of health-related quality of life were evaluated using the self-administered Medical Outcomes Study: 36-Item Short Form Survey. Crude and adjusted linear regression coefficients (beta) and the corresponding 95% confidence intervals (95% CI) were computed to estimate the associations between being labelled as an osteoarthritis case and health-related quality of life.

Results

Regardless of disease medical labelling, individuals with osteoarthritis scored significantly lower physical health-related quality of life when compared to those without joint disease (kneeunexposed: beta = −5.3, 95% CI: −7.6, −3.1; kneeexposed: beta = −6.0, 95% CI: −8.4, −3.7; hipunexposed: beta = −6.0, 95% CI: −9.8, −2.3; hipexposed: beta = −11.0, 95% CI: −15.6, −6.4; handunexposed: beta = −4.3, 95% CI: −6.5, −2.0; handexposed: beta = −4.3, 95% CI: −6.6, −2.1). The same was not observed regarding mental health-related quality of life. Among subjects with clinically confirmed osteoarthritis, the medical labelling of this joint disease was not significantly associated to health-related quality of life.

Conclusions

The labelling of knee, hip and hand osteoarthritis diagnosis may not add specific benefit to osteoarthritis patients in terms of its capability to improve health-related quality of life.
Literature
1.
2.
Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basanez MG, Baxter A, Bell ML, Benjamin EJ, et al.: Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380: 2197–2223. 10.1016/S0140-6736(12)61689-4CrossRefPubMed
3.
Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, Amann M, Anderson HR, Andrews KG, Aryee M, Atkinson C, Bacchus LJ, Bahalim AN, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell ML, Blore JD, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce NG, Brunekreef B, Bryan-Hancock C, Bucello C, et al.: A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380: 2224–2260. 10.1016/S0140-6736(12)61766-8PubMedCentralCrossRefPubMed
4.
Ware J, Kosinski M, Keller S: SF-36 Physical and Mental Health Summary Scales: A User’s Manual. The Health Institute, Boston: MA; 1994.
5.
Lidgren L, Smolen J, Bentley G, Delmas P, Woolf A, Åkesson K, Compston J, Thorngren K, Riel P: European Action Towards better Musculoskeletal Health: A Public Health Strategy to Reduce the Burden of Musculoskeletal Conditions. The Bone & Joint Decade, Sweden; 2005.
6.
Cole A, Gill T, Taylor A, Hill C: Prevalence and associations of hand pain in the community: results from a population-based study. Scand J Rheumatol 2011, 40: 145–149.PubMed
7.
Muraki S, Akune T, Oka H, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N: Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: the ROAD study. Osteoarthritis Cartilage 2010, 18: 1227–1234. 10.1016/j.joca.2010.06.001CrossRefPubMed
8.
Rat A, Guillemin F, Osnowycz G, Delagoutte J, Cuny C, Mainard D, Baumann C: Total hip or knee replacement for osteoarthritis: mid- and long-term quality of life. Arthritis Care Res 2010, 62: 54–62. 10.1002/acr.20014CrossRef
9.
10.
11.
Juni P, Reichenbach S, Dieppe P: Osteoarthritis: rational approach to treating the individual. Best Pract Res Clin Rheumatol 2006, 20: 721–740. 10.1016/j.berh.2006.05.002CrossRefPubMed
12.
Patrick D, Deyo RA: Generic and disease-specific measures in assessing health status and quality of life. Med Care 1989, 27: 217–232. 10.1097/00005650-198903001-00018CrossRef
13.
Bullinger M, Anderson R, Cella D, Aaronson N: Developing and evaluating cross-cultural instruments from minimum requirements to optimal models. Qual Life Res 1993, 2: 451–459. 10.1007/BF00422219CrossRefPubMed
14.
WHO: Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL) Qual Life Res 1993, 2: 153–159. 10.1007/BF00435734
15.
Montazeri ATA, Mohagheghi MA, Roshan R, Tavoli Z: Disclosure of cancer diagnosis and quality of life in cancer patients: should it be the same everywhere? BMC Cancer 2009, 29: 39–46. 10.1186/1471-2407-9-39CrossRef
16.
Montazeri AHD, Milroy R, McEwen J, Gillis CR: Does knowledge of cancer diagnosis affect quality of life? a methodological challenge. BMC Cancer 2004, 4: 21. 10.1186/1471-2407-4-21PubMedCentralCrossRefPubMed
17.
McDonald SA, Hutchinson SJ, Palmateer NE, Allen E, Cameron SO, Goldberg DJ, Taylor A: Decrease in health-related quality of life associated with awareness of hepatitis C virus infection among people who inject drugs in Scotland. J Hepatol 2013, 58: 460–466. 10.1016/j.jhep.2012.11.004CrossRefPubMed
18.
Azevedo A, Bettencourt P, Alvelos M, Martins E, Abreu-Lima C, Hense HW, Barros H: Health-related quality of life and stages of heart failure. Int J Cardiol 2008, 129: 238–244. 10.1016/j.ijcard.2007.07.091CrossRefPubMed
19.
Bijlsma J, Berenbaum F, Lafeber F: Osteoarthritis: an update with relevance for clinical practice. Lancet 2011, 377: 2115–2126. 10.1016/S0140-6736(11)60243-2CrossRefPubMed
20.
Santos A, Barros H: Smoking patterns in a community sample of Portuguese adults, 1999–2000. Prev Med 2004, 38: 114–119. 10.1016/j.ypmed.2003.09.040CrossRefPubMed
21.
Severo M, Lucas R, Costa L, André R, Barros H: Algoritmo para o rastreio da osteoartrose do joelho, coluna, mão e anca [An algorithm for screening osteoarthritis of the knee, spine, hand and hip]. Acta Reumatol Port 2006, 31: S93-S94.
22.
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, Howell D, Kaplan D, Koopman W, Longley S, Mankin H, McShane DJ, Medsger T, Meenan R, Mikkelsen W, Moskowitz R, Murphy W, Rothschild B, Segak M, Sokoloff L, Wolfe F: Development of criteria for the classification and reporting of osteoarthritis. classification of osteoarthritis of the knee. Diagnostic and therapeutic criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986, 29: 1039–1049. 10.1002/art.1780290816CrossRefPubMed
23.
Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, Brown C, Cooke TD, Daniel W, Feldman D, Greenwald R, Hochberg M, Howell D, Ike R, Kapila P, Kaplan D, Koopman W, Marino C, McDonald E, McShane DJ, Medsger T, Michel B, Murphy WA, Osial T, Ramsey-Goldman R, Rothschild B, Wolfe F: The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum 1991, 34: 505–514. 10.1002/art.1780340502CrossRefPubMed
24.
Altman R, Alarcón G, Appelrouth D, Bloch D, Borenstein D, Brandt K, Brown C, Cooke TD, Daniel W, Gray R, Greenwald R, Hochberg M, Howell D, Ike R, Kapila P, Kaplan D, Koopman W, Longley S, McShane DJ, Medsger T, Michel B, Murphy W, Osial T, Ramsey-Goldman R, Rothschild B, Stark K, Wolfe F: The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis Rheum 1990, 33: 1601–1610. 10.1002/art.1780331101CrossRefPubMed
25.
Severo M, Santos AC, Lopes C, Barros H: Fiabilidade e validade dos conceitos teóricos das dimensões de saúde física e mental da versão portuguesa do MOS SF-36. Acta Med Port 2006, 19: 281–288.PubMed
26.
Murphy L, Helmick CG: The impact of osteoarthritis in the United States: a population-health perspective. Am J Nurs 2012, 112: S13-S19. 10.1097/01.NAJ.0000412646.80054.21CrossRefPubMed
27.
Moskowitz RW: The burden of osteoarthritis: clinical and quality-of-life issues. Am J Manag Care 2009, 15: S223-S229.PubMed
28.
Alkan BM, Fidan F, Tosun A, Ardicoglu O: Quality of life and self-reported disability in patients with knee osteoarthritis. Mod Rheumatol 2014, 24: 166. 10.3109/14397595.2013.854046CrossRefPubMed
29.
30.
Arden N, Nevitt MC: Osteoarthritis: epidemiology. Best Pract Res Clin Rheumatol 2006, 20: 3–25. 10.1016/j.berh.2005.09.007CrossRefPubMed
31.
Meyer G, Hackemann A, Penna-Martinez M, Badenhoop K: What affects the quality of life in autoimmune Addison’s disease? Horm Metab Res 2013, 45: 92–95. 10.1055/s-0032-1331766CrossRefPubMed
32.
Bozcuk H, Erdoğan V, Eken C, Ciplak E, Samur M, Ozdoğan M, Savaş B: Does awareness of diagnosis make any difference to quality of life? determinants of emotional functioning in a group of cancer patients in Turkey. Support Care Cancer 2002, 10: 51–57. 10.1007/s005200100308CrossRefPubMed
33.
Husson O, Mols F, van de Poll-Franse L: The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review. Ann Oncol 2011, 22: 761–772. 10.1093/annonc/mdq413PubMedCentralCrossRefPubMed
34.
Atesci F, Baltalarli B, Oguzhanoglu N, Karadag F, Ozdel O, Karagoz N: Psychiatric morbidity among cancer patients and awareness of illness. Support Care Cancer 2004, 12: 161–167. 10.1007/s00520-003-0585-yCrossRefPubMed
35.
Peppercorn JM, Smith TJ, Helft PR, Debono DJ, Berry SR, Wollins DS, Hayes DM, Von Roenn JH, Schnipper LE: American society of clinical oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol 2011, 29: 755–760. 10.1200/JCO.2010.33.1744CrossRefPubMed
36.
Wylde V, Dieppe P, Hewlett S, Learmonth ID: Total knee replacement: is it really an effective procedure for all? Knee 2007, 14: 417–423. 10.1016/j.knee.2007.06.001CrossRefPubMed
37.
Zhang W, Moskowitz R, Nuki G, Abramson S, Altman R, Arden N, Bierma-Zeinstra S, Brandt K, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P: OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 2008, 16: 137–162. 10.1016/j.joca.2007.12.013CrossRefPubMed
38.
39.
O’Connor A, Wicker C, Germino B: Understanding the cancer patient’s search for meaning. Cancer Nurs 1990, 13: 167–175. 10.1097/00002820-199006000-00006CrossRefPubMed
40.
Zhang W, Doherty M: Pharmacological treatments: the example of osteoarthritis. In Chronic Pain Epidemiology: From Aetiology to Public Health. Edited by: Croft P, Blyth FM, Windt D. Oxford University Press, Oxford; 2010:289–312. 10.1093/acprof:oso/9780199235766.003.0023CrossRef
41.
Simpson CF, Boyd CM, Carlson MC, Griswold ME, Guralnik JM, Fried LP: Agreement between self-report of disease diagnoses and medical record validation in disabled older women: factors that modify agreement. J Am Geriatr Soc 2004, 52: 123–127. 10.1111/j.1532-5415.2004.52021.xCrossRefPubMed
42.
Brandt K, Dieppe P, Radin E: Etiopathogenesis of osteoarthritis. Rheum Dis Clin North Am 2008, 34: 531–559. 10.1016/j.rdc.2008.05.011CrossRefPubMed
43.
Brauer C, Thomsen JF, Loft IP, Mikkelsen S: Can we rely on retrospective pain assessments? Am J Epidemiol 2003, 157: 552–557. 10.1093/aje/kwg017CrossRefPubMed
44.
Efron B, Tibshirani R: An Introduction to the Bootstrap. Chapman & Hall, New York, NY; 1993.CrossRef
Metadata
Title
Osteoarthritis medical labelling and health-related quality of life in the general population
Authors
Sara Lourenço
Raquel Lucas
Fábio Araújo
Mónica Bogas
Rui André Santos
Henrique Barros
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2014
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-014-0146-8

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