Skip to main content
Top
Published in: International Journal for Equity in Health 1/2016

Open Access 01-12-2016 | Research

Wealth and cardiovascular health: a cross-sectional study of wealth-related inequalities in the awareness, treatment and control of hypertension in high-, middle- and low-income countries

Authors: Benjamin Palafox, Martin McKee, Dina Balabanova, Khalid F. AlHabib, Alvaro Jr Avezum, Ahmad Bahonar, Noorhassim Ismail, Jephat Chifamba, Clara K. Chow, Daniel J. Corsi, Gilles R. Dagenais, Rafael Diaz, Rajeev Gupta, Romaina Iqbal, Manmeet Kaur, Rasha Khatib, Annamarie Kruger, Iolanthe Marike Kruger, Fernando Lanas, Patricio Lopez-Jaramillo, Fu Minfan, Viswanathan Mohan, Prem K. Mony, Aytekin Oguz, Lia M. Palileo-Villanueva, Pablo Perel, Paul Poirier, Sumathy Rangarajan, Lei Rensheng, Annika Rosengren, Biju Soman, David Stuckler, S. V. Subramanian, Koon Teo, Lungiswa P. Tsolekile, Andreas Wielgosz, Peng Yaguang, Karen Yeates, Mo Yongzhen, Khalid Yusoff, Rita Yusuf, Afzalhussein Yusufali, Katarzyna Zatońska, Salim Yusuf

Published in: International Journal for Equity in Health | Issue 1/2016

Login to get access

Abstract

Background

Effective policies to control hypertension require an understanding of its distribution in the population and the barriers people face along the pathway from detection through to treatment and control. One key factor is household wealth, which may enable or limit a household’s ability to access health care services and adequately control such a chronic condition. This study aims to describe the scale and patterns of wealth-related inequalities in the awareness, treatment and control of hypertension in 21 countries using baseline data from the Prospective Urban and Rural Epidemiology study.

Methods

A cross-section of 163,397 adults aged 35 to 70 years were recruited from 661 urban and rural communities in selected low-, middle- and high-income countries (complete data for this analysis from 151,619 participants). Using blood pressure measurements, self-reported health and household data, concentration indices adjusted for age, sex and urban-rural location, we estimate the magnitude of wealth-related inequalities in the levels of hypertension awareness, treatment, and control in each of the 21 country samples.

Results

Overall, the magnitude of wealth-related inequalities in hypertension awareness, treatment, and control was observed to be higher in poorer than in richer countries. In poorer countries, levels of hypertension awareness and treatment tended to be higher among wealthier households; while a similar pro-rich distribution was observed for hypertension control in countries at all levels of economic development. In some countries, hypertension awareness was greater among the poor (Sweden, Argentina, Poland), as was treatment (Sweden, Poland) and control (Sweden).

Conclusion

Inequality in hypertension management outcomes decreased as countries became richer, but the considerable variation in patterns of wealth-related inequality - even among countries at similar levels of economic development - underscores the importance of health systems in improving hypertension management for all. These findings show that some, but not all, countries, including those with limited resources, have been able to achieve more equitable management of hypertension; and strategies must be tailored to national contexts to achieve optimal impact at population level.
Appendix
Available only for authorised users
Literature
1.
go back to reference World Health Organization. Global action plan for the prevention and control of noncommunicable diseases 2013–2020. Geneva: WHO; 2013. World Health Organization. Global action plan for the prevention and control of noncommunicable diseases 2013–2020. Geneva: WHO; 2013.
2.
go back to reference Perel P, Bianco E, Poulter N, Prabhakaran D, Pais P, Ralston J, et al. Reducing premature cardiovascular mortality by 2025. Glob Heart. 2015;10(2):97–8.CrossRefPubMed Perel P, Bianco E, Poulter N, Prabhakaran D, Pais P, Ralston J, et al. Reducing premature cardiovascular mortality by 2025. Glob Heart. 2015;10(2):97–8.CrossRefPubMed
3.
go back to reference Chow CK, Teo KK, Rangarajan S, Islam S, Gupta R, Avezum A, et al. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013;310(9):959–68.CrossRefPubMed Chow CK, Teo KK, Rangarajan S, Islam S, Gupta R, Avezum A, et al. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013;310(9):959–68.CrossRefPubMed
4.
go back to reference Basu S, Millett C. Social epidemiology of hypertension in middle-income countries: determinants of prevalence, diagnosis, treatment, and control in the WHO SAGE study. Hypertension. 2013;62(1):18–26.CrossRefPubMed Basu S, Millett C. Social epidemiology of hypertension in middle-income countries: determinants of prevalence, diagnosis, treatment, and control in the WHO SAGE study. Hypertension. 2013;62(1):18–26.CrossRefPubMed
5.
go back to reference Lloyd-Sherlock P, Beard J, Minicuci N, Ebrahim S, Chatterji S. Hypertension among older adults in low- and middle-income countries: prevalence, awareness and control. Int J Epidemiol. 2014;43(1):116–28.CrossRefPubMedPubMedCentral Lloyd-Sherlock P, Beard J, Minicuci N, Ebrahim S, Chatterji S. Hypertension among older adults in low- and middle-income countries: prevalence, awareness and control. Int J Epidemiol. 2014;43(1):116–28.CrossRefPubMedPubMedCentral
6.
go back to reference Dalstra J, Kunst A, Borrell C, Breeze E, Cambois E, Costa G, et al. Socioeconomic differences in the prevalence of common chronic diseases: an overview of eight European countries. Int J Epidemiol. 2005;34(2):316–26.CrossRefPubMed Dalstra J, Kunst A, Borrell C, Breeze E, Cambois E, Costa G, et al. Socioeconomic differences in the prevalence of common chronic diseases: an overview of eight European countries. Int J Epidemiol. 2005;34(2):316–26.CrossRefPubMed
7.
go back to reference Teo K, Chow CK, Vaz M, Rangarajan S, Yusuf S, Group PI-W. The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries. Am Heart J. 2009;158(1):1–7. e1.CrossRefPubMed Teo K, Chow CK, Vaz M, Rangarajan S, Yusuf S, Group PI-W. The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries. Am Heart J. 2009;158(1):1–7. e1.CrossRefPubMed
8.
go back to reference Yusuf S, Islam S, Chow CK, Rangarajan S, Dagenais G, Diaz R, et al. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet. 2011;378(9798):1231–43.CrossRefPubMed Yusuf S, Islam S, Chow CK, Rangarajan S, Dagenais G, Diaz R, et al. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet. 2011;378(9798):1231–43.CrossRefPubMed
10.
go back to reference Corsi DJ, Subramanian SV, Chow CK, McKee M, Chifamba J, Dagenais G, et al. Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries. Am Heart J. 2013;166(4):636–46. e4.CrossRefPubMed Corsi DJ, Subramanian SV, Chow CK, McKee M, Chifamba J, Dagenais G, et al. Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries. Am Heart J. 2013;166(4):636–46. e4.CrossRefPubMed
11.
go back to reference Yusuf S, Rangarajan S, Teo K, Islam S, Li W, Liu L, et al. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014;371(9):818–27.CrossRefPubMed Yusuf S, Rangarajan S, Teo K, Islam S, Li W, Liu L, et al. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014;371(9):818–27.CrossRefPubMed
12.
go back to reference Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364(9438):937–52.CrossRefPubMed Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364(9438):937–52.CrossRefPubMed
13.
go back to reference World Health Organization. WHO STEPS surveillance manual: the WHO STEPwise approach to chronic disease risk factor surveillance. Geneva: World Health Organization; 2005. World Health Organization. WHO STEPS surveillance manual: the WHO STEPwise approach to chronic disease risk factor surveillance. Geneva: World Health Organization; 2005.
15.
go back to reference Gee ME, Campbell N, Sarrafzadegan N, Jafar T, Khalsa TK, Mangat B, et al. Standards for the uniform reporting of hypertension in adults using population survey data: recommendations from the World Hypertension League Expert Committee. J Clin Hypertens (Greenwich). 2014;16(11):773–81.CrossRef Gee ME, Campbell N, Sarrafzadegan N, Jafar T, Khalsa TK, Mangat B, et al. Standards for the uniform reporting of hypertension in adults using population survey data: recommendations from the World Hypertension League Expert Committee. J Clin Hypertens (Greenwich). 2014;16(11):773–81.CrossRef
16.
go back to reference Rutstein SO, Johnson K. The DHS Wealth Index - DHS Comparative Reports No. 6 (August 2004). Calverton: ORC Macro; 2004. Rutstein SO, Johnson K. The DHS Wealth Index - DHS Comparative Reports No. 6 (August 2004). Calverton: ORC Macro; 2004.
17.
go back to reference Filmer D, Pritchett L. Estimating wealth effects without expenditure data—or tears: an application to educational enrollments in states of India*. Demography. 2001;38(1):115–32.PubMed Filmer D, Pritchett L. Estimating wealth effects without expenditure data—or tears: an application to educational enrollments in states of India*. Demography. 2001;38(1):115–32.PubMed
18.
go back to reference Vyas S, Kumaranayake L. Constructing socio-economic status indices: how to use principal components analysis. Health Policy Plan. 2006;21(6):459–68.CrossRefPubMed Vyas S, Kumaranayake L. Constructing socio-economic status indices: how to use principal components analysis. Health Policy Plan. 2006;21(6):459–68.CrossRefPubMed
19.
go back to reference Kakwani N, Wagstaff A, van Doorslaer E. Socioeconomic inequalities in health: Measurement, computation, and statistical inference. J Econ. 1997;77(1):87–103.CrossRef Kakwani N, Wagstaff A, van Doorslaer E. Socioeconomic inequalities in health: Measurement, computation, and statistical inference. J Econ. 1997;77(1):87–103.CrossRef
20.
go back to reference O’Donnell O, van Doorslaer E, Wagstaff A, Lindelow M. Analyzing health equity using household survey data: a guide to techniques and their implementation. Washington: The World Bank; 2008. O’Donnell O, van Doorslaer E, Wagstaff A, Lindelow M. Analyzing health equity using household survey data: a guide to techniques and their implementation. Washington: The World Bank; 2008.
21.
go back to reference Oehlert GW. A note on the delta method. Am Stat. 1992;46(1):27–9. Oehlert GW. A note on the delta method. Am Stat. 1992;46(1):27–9.
22.
go back to reference Wagstaff A. The concentration index of a binary outcome revisited. Health Econ. 2011;20(10):1155–60.CrossRefPubMed Wagstaff A. The concentration index of a binary outcome revisited. Health Econ. 2011;20(10):1155–60.CrossRefPubMed
23.
go back to reference McKinnon B, Harper S, Kaufman JS, Bergevin Y. Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis. Lancet Glob Health. 2014;2(3):e165–73.CrossRefPubMed McKinnon B, Harper S, Kaufman JS, Bergevin Y. Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis. Lancet Glob Health. 2014;2(3):e165–73.CrossRefPubMed
24.
go back to reference StataCorp. Stata Statistical Software: Release 13. College Station: StataCorp LP; 2013. StataCorp. Stata Statistical Software: Release 13. College Station: StataCorp LP; 2013.
25.
go back to reference United Nations. Transforming our world: the 2030 agenda for sustainable development. New York: United Nations; 2015. United Nations. Transforming our world: the 2030 agenda for sustainable development. New York: United Nations; 2015.
26.
go back to reference Prince MJ, Ebrahim S, Acosta D, Ferri CP, Guerra M, Huang Y, et al. Hypertension prevalence, awareness, treatment and control among older people in Latin America, India and China: a 10/66 cross-sectional population-based survey. J Hypertens. 2012;30(1):177–87.CrossRefPubMed Prince MJ, Ebrahim S, Acosta D, Ferri CP, Guerra M, Huang Y, et al. Hypertension prevalence, awareness, treatment and control among older people in Latin America, India and China: a 10/66 cross-sectional population-based survey. J Hypertens. 2012;30(1):177–87.CrossRefPubMed
27.
go back to reference Gee ME, Campbell NR, Gwadry-Sridhar F, Nolan RP, Kaczorowski J, Bienek A, et al. Antihypertensive medication use, adherence, stops, and starts in Canadians with hypertension. Can J Cardiol. 2012;28(3):383–9.CrossRefPubMed Gee ME, Campbell NR, Gwadry-Sridhar F, Nolan RP, Kaczorowski J, Bienek A, et al. Antihypertensive medication use, adherence, stops, and starts in Canadians with hypertension. Can J Cardiol. 2012;28(3):383–9.CrossRefPubMed
28.
go back to reference Wolf-Maier K, Cooper RS, Kramer H, Banegas JR, Giampaoli S, Joffres MR, et al. Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension. 2004;43(1):10–7.CrossRefPubMed Wolf-Maier K, Cooper RS, Kramer H, Banegas JR, Giampaoli S, Joffres MR, et al. Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension. 2004;43(1):10–7.CrossRefPubMed
29.
go back to reference Ebrahimi M, Mansournia MA, Haghdoost AA, Abazari A, Alaeddini F, Mirzazadeh A, et al. Social disparities in prevalence, treatment and control of hypertension in Iran: second National Surveillance of Risk Factors of Noncommunicable Diseases, 2006. J Hypertens. 2010;28(8):1620–9.CrossRefPubMed Ebrahimi M, Mansournia MA, Haghdoost AA, Abazari A, Alaeddini F, Mirzazadeh A, et al. Social disparities in prevalence, treatment and control of hypertension in Iran: second National Surveillance of Risk Factors of Noncommunicable Diseases, 2006. J Hypertens. 2010;28(8):1620–9.CrossRefPubMed
30.
go back to reference Firmo JO, Barreto SM, Lima-Costa MF. The Bambui Health and Aging Study (BHAS): factors associated with the treatment of hypertension in older adults in the community. Cad Saude Publica. 2003;19(3):817–27.CrossRefPubMed Firmo JO, Barreto SM, Lima-Costa MF. The Bambui Health and Aging Study (BHAS): factors associated with the treatment of hypertension in older adults in the community. Cad Saude Publica. 2003;19(3):817–27.CrossRefPubMed
31.
go back to reference Muntner P, Gu D, Wu X, Duan X, Wenqi G, Whelton PK, et al. Factors associated with hypertension awareness, treatment, and control in a representative sample of the chinese population. Hypertension. 2004;43(3):578–85.CrossRefPubMed Muntner P, Gu D, Wu X, Duan X, Wenqi G, Whelton PK, et al. Factors associated with hypertension awareness, treatment, and control in a representative sample of the chinese population. Hypertension. 2004;43(3):578–85.CrossRefPubMed
32.
go back to reference Bovet P, Ross AG, Gervasoni JP, Mkamba M, Mtasiwa DM, Lengeler C, et al. Distribution of blood pressure, body mass index and smoking habits in the urban population of Dar es Salaam, Tanzania, and associations with socioeconomic status. Int J Epidemiol. 2002;31(1):240–7.CrossRefPubMed Bovet P, Ross AG, Gervasoni JP, Mkamba M, Mtasiwa DM, Lengeler C, et al. Distribution of blood pressure, body mass index and smoking habits in the urban population of Dar es Salaam, Tanzania, and associations with socioeconomic status. Int J Epidemiol. 2002;31(1):240–7.CrossRefPubMed
33.
go back to reference Gee ME, Bienek A, McAlister FA, Robitaille C, Joffres M, Tremblay MS, et al. Factors associated with lack of awareness and uncontrolled high blood pressure among Canadian adults with hypertension. Can J Cardiol. 2012;28(3):375–82.CrossRefPubMed Gee ME, Bienek A, McAlister FA, Robitaille C, Joffres M, Tremblay MS, et al. Factors associated with lack of awareness and uncontrolled high blood pressure among Canadian adults with hypertension. Can J Cardiol. 2012;28(3):375–82.CrossRefPubMed
34.
go back to reference Risso-Gill I, Balabanova D, Majid F, Ng KK, Yusoff K, Mustapha F, et al. Understanding the modifiable health systems barriers to hypertension management in Malaysia: a multi-method health systems appraisal approach. BMC Health Serv Res. 2015;15:254.CrossRefPubMedPubMedCentral Risso-Gill I, Balabanova D, Majid F, Ng KK, Yusoff K, Mustapha F, et al. Understanding the modifiable health systems barriers to hypertension management in Malaysia: a multi-method health systems appraisal approach. BMC Health Serv Res. 2015;15:254.CrossRefPubMedPubMedCentral
35.
go back to reference Legido-Quigley H, Camacho Lopez PA, Balabanova D, Perel P, Lopez-Jaramillo P, Nieuwlaat R, et al. Patients’ knowledge, attitudes, behaviour and health care experiences on the prevention, detection, management and control of hypertension in Colombia: a qualitative study. PLoS One. 2015;10(4):e0122112.CrossRefPubMedPubMedCentral Legido-Quigley H, Camacho Lopez PA, Balabanova D, Perel P, Lopez-Jaramillo P, Nieuwlaat R, et al. Patients’ knowledge, attitudes, behaviour and health care experiences on the prevention, detection, management and control of hypertension in Colombia: a qualitative study. PLoS One. 2015;10(4):e0122112.CrossRefPubMedPubMedCentral
36.
go back to reference Khatib R, McKee M, Shannon H, Chow C, Rangarajan S, Teo K, et al. Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data. The Lancet. (accepted and in press, 2015). Khatib R, McKee M, Shannon H, Chow C, Rangarajan S, Teo K, et al. Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data. The Lancet. (accepted and in press, 2015).
37.
go back to reference Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ. Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med. 2009;122(3):290–300.CrossRefPubMed Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ. Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med. 2009;122(3):290–300.CrossRefPubMed
38.
go back to reference Cheraghali AM, Nikfar S, Behmanesh Y, Rahimi V, Habibipour F, Tirdad R, et al. Evaluation of availability, accessibility and prescribing pattern of medicines in the Islamic Republic of Iran. East Mediterr Health J. 2004;10(3):406–15.PubMed Cheraghali AM, Nikfar S, Behmanesh Y, Rahimi V, Habibipour F, Tirdad R, et al. Evaluation of availability, accessibility and prescribing pattern of medicines in the Islamic Republic of Iran. East Mediterr Health J. 2004;10(3):406–15.PubMed
39.
go back to reference Barreto MN, Cesse EA, Lima RF, Marinho MG, Specht Yda S, Carvalho EM, et al. Analysis of access to hypertensive and diabetic drugs in the Family Health Strategy, State of Pernambuco, Brazil. Rev Bras Epidemiol. 2015;18(2):413–24.CrossRefPubMed Barreto MN, Cesse EA, Lima RF, Marinho MG, Specht Yda S, Carvalho EM, et al. Analysis of access to hypertensive and diabetic drugs in the Family Health Strategy, State of Pernambuco, Brazil. Rev Bras Epidemiol. 2015;18(2):413–24.CrossRefPubMed
40.
go back to reference Lee JT, Hamid F, Pati S, Atun R, Millett C. Impact of noncommunicable disease multimorbidity on healthcare utilisation and out-of-pocket expenditures in middle-income countries: cross sectional analysis. PLoS One. 2015;10(7):e0127199.CrossRefPubMedPubMedCentral Lee JT, Hamid F, Pati S, Atun R, Millett C. Impact of noncommunicable disease multimorbidity on healthcare utilisation and out-of-pocket expenditures in middle-income countries: cross sectional analysis. PLoS One. 2015;10(7):e0127199.CrossRefPubMedPubMedCentral
41.
go back to reference Adler AJ, Prabhakaran D, Bovet P, Kazi DS, Mancia G, Mungal-Singh V, et al. Reducing cardiovascular mortality through prevention and management of raised blood pressure: a World Heart Federation Roadmap. Glob Heart. 2015;10(2):111–22.CrossRefPubMed Adler AJ, Prabhakaran D, Bovet P, Kazi DS, Mancia G, Mungal-Singh V, et al. Reducing cardiovascular mortality through prevention and management of raised blood pressure: a World Heart Federation Roadmap. Glob Heart. 2015;10(2):111–22.CrossRefPubMed
Metadata
Title
Wealth and cardiovascular health: a cross-sectional study of wealth-related inequalities in the awareness, treatment and control of hypertension in high-, middle- and low-income countries
Authors
Benjamin Palafox
Martin McKee
Dina Balabanova
Khalid F. AlHabib
Alvaro Jr Avezum
Ahmad Bahonar
Noorhassim Ismail
Jephat Chifamba
Clara K. Chow
Daniel J. Corsi
Gilles R. Dagenais
Rafael Diaz
Rajeev Gupta
Romaina Iqbal
Manmeet Kaur
Rasha Khatib
Annamarie Kruger
Iolanthe Marike Kruger
Fernando Lanas
Patricio Lopez-Jaramillo
Fu Minfan
Viswanathan Mohan
Prem K. Mony
Aytekin Oguz
Lia M. Palileo-Villanueva
Pablo Perel
Paul Poirier
Sumathy Rangarajan
Lei Rensheng
Annika Rosengren
Biju Soman
David Stuckler
S. V. Subramanian
Koon Teo
Lungiswa P. Tsolekile
Andreas Wielgosz
Peng Yaguang
Karen Yeates
Mo Yongzhen
Khalid Yusoff
Rita Yusuf
Afzalhussein Yusufali
Katarzyna Zatońska
Salim Yusuf
Publication date
01-12-2016
Publisher
BioMed Central
Published in
International Journal for Equity in Health / Issue 1/2016
Electronic ISSN: 1475-9276
DOI
https://doi.org/10.1186/s12939-016-0478-6

Other articles of this Issue 1/2016

International Journal for Equity in Health 1/2016 Go to the issue