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Cancer Cell International
Published in: Cancer Cell International 1/2019

Open Access 01-12-2019 | Colorectal Cancer | Review

Resveratrol is a promising agent for colorectal cancer prevention and treatment: focus on molecular mechanisms

Authors: Mohadese Honari, Rana Shafabakhsh, Russel J. Reiter, Hamed Mirzaei, Zatollah Asemi

Published in: Cancer Cell International | Issue 1/2019

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Abstract

Colorectal cancer (CRC) is the third most common cancer and one of the main causes of cancer death entire the world. Environmental, dietary, and lifestyle factors including red meat consumption, cigarette smoking, alcohol intake and family history are the most important risk factors of CRC. Multiple pathways including inflammation, oxidative stress, and apoptosis are involved in its incidence and progression. Resveratrol, a polyphenolic compound, has different pharmacologic functions including anti-inflammation, cancer prevention, lipid-lowering effect, and hypoglycemic effect. Many studies have proved that resveratrol might also represent a chemo preventive effect on CRC. Thus, the aim of the current review is to depict the role of resveratrol in treatment of CRC in a molecular manner.
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Metadata
Title
Resveratrol is a promising agent for colorectal cancer prevention and treatment: focus on molecular mechanisms
Authors
Mohadese Honari
Rana Shafabakhsh
Russel J. Reiter
Hamed Mirzaei
Zatollah Asemi
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Cancer Cell International / Issue 1/2019
Electronic ISSN: 1475-2867
DOI
https://doi.org/10.1186/s12935-019-0906-y

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