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BMC Medicine
Published in: BMC Medicine 1/2022

Open Access 01-12-2022 | Research article

Effects of providing free hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China: a randomized controlled trial

Authors: Xin Ye, Dawei Zhu, Siyuan Chen, Xuefeng Shi, Rui Gong, Juncheng Wang, Huibin Zuo, Ping He

Published in: BMC Medicine | Issue 1/2022

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Abstract

Background

Hearing loss has been associated with serious health problems around the globe. Previous studies have found the positive effects of fitting hearing aids on health, but few studies were conducted in developing countries. The aim of this study is to examine the effects of hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China.

Methods

In this randomized controlled trial (RCT), participants aged 45 and above were randomly assigned to the treatment group prescribing with hearing aids or to the control group with no intervention. Trial outcomes for 385 participants were collected during the 20-month follow-up study. Using the difference-in-difference approach, our primary outcomes were hearing-related quality of life (QoL) and generic QoL.

Results

The intervention led to improvements in hearing-related QoL, presenting as the reduction in Hearing Handicap Inventory for the Elderly Screening Version (HHIE-S) scores (interaction coefficient = − 2.86, p = 0.005), HHIE-S-Emotional scores (interaction coefficient = − 1.42, p = 0.029), and HHIE-S-Situational scores (interaction coefficient = − 1.43, p = 0.007). The intervention was also effective in alleviating the increase in depressive symptoms (interaction coefficient = − 0.14, p = 0.042). Subgroup analysis revealed that the effects were only shown among people with social activities or active social networks.

Conclusions

Our study is the first RCT in China to measure the health effects and heterogeneity of hearing aid interventions. Wearing hearing aids can help improve hearing-related QoL and alleviate the increase in depressive symptoms. The intervention is expected to be applicable to similar settings in other developing countries to combat hearing-related health problems.

Trial registration

Chinese Clinical Trial Registry, ChiCTR1900024739​. Registered on 26 July 2019.
Literature
1.
Moon IJ, Baek SY, Cho Y-S. Hearing aid use and associated factors in South Korea. Medicine. 2015;94(42):e1580.
2.
3.
Arlinger S. Negative consequences of uncorrected hearing loss-a review. Int J Audiol. 2003;42:2S17–20.PubMed
4.
Stevens G, Flaxman S, Brunskill E, Mascarenhas M, Mathers CD, Finucane M. Global and regional hearing impairment prevalence: an analysis of 42 studies in 29 countries. Eur J Public Health. 2013;23(1):146–52.CrossRef
5.
Xiangyang H, Xiaoying Z, Furong M, Mo L, Rui H, Lijun Z, et al. Prevalence of hearing disorders in China: a population-based survey in four provinces of China. Chin J Otorhinolaryngol Head Neck Surg. 2016;51(11):819–25.
6.
Looi LM, Ganten D, McGrath PF, Gross M, Griffin GE. Hearing loss: a global health issue. Lancet. 2015;385(9972):943–4.CrossRef
7.
8.
Li C-M, Zhang X, Hoffman HJ, Cotch MF, Themann CL, Wilson MR. Hearing impairment associated with depression in US adults, National Health and Nutrition Examination Survey 2005-2010. JAMA Otolaryngol Head Neck Surg. 2014;140(4):293–302.CrossRef
9.
Lin FR, Thorpe R, Gordon-Salant S, Ferrucci L. Hearing loss prevalence and risk factors among older adults in the United States. J Gerontol A Biol Scci Med Sci. 2011;66(5):582–90.CrossRef
10.
Jung D, Bhattacharyya N. Association of hearing loss with decreased employment and income among adults in the United States. Ann Otol Rhinol Laryngol. 2012;121(12):771–5.CrossRef
11.
Mener DJ, Betz J, Genther DJ, Chen D, Lin FR. Hearing loss and depression in older adults. J Am Geriatr Soc. 2013;61(9):1627–9.CrossRef
12.
Pronk M, Deeg DJ, Smits C, Twisk JW, van Tilburg TG, Festen JM, et al. Hearing loss in older persons: does the rate of decline affect psychosocial health? J Aging Health. 2014;26(5):703–23.CrossRef
13.
Feigin V. Global, regional, and national incidence, prevalence, and years lived with disability for 310 acute and chronic diseases and injuries, 1990-2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016;388(10053):1545–602.CrossRef
14.
Ferguson MA, Woolley A, Munro KJ. The impact of self-efficacy, expectations, and readiness on hearing aid outcomes. Int J Audiol. 2016;55(sup3):S34–41.CrossRef
15.
Nieman CL, Marrone N, Mamo SK, Betz J, Choi JS, Contrera KJ, et al. The Baltimore HEARS Pilot Study: an affordable, accessible, community-delivered hearing care intervention. Gerontologist. 2017;57(6):1173–86.PubMed
16.
Dawes P, Cruickshanks KJ, Fischer ME, Klein BE, Klein R, Nondahl DM. Hearing-aid use and long-term health outcomes: hearing handicap, mental health, social engagement, cognitive function, physical health, and mortality. Int J Audiol. 2015;54(11):838–44.CrossRef
17.
Joore MA, Potjewijd J, Timmerman AA, Anteunis LJ. Response shift in the measurement of quality of life in hearing impaired adults after hearing aid fitting. Qual Life Res. 2002;11(4):299–307.CrossRef
18.
Joore MA, Brunenberg DE, Chenault MN, Anteunis LJ. Societal effects of hearing aid fitting among the moderately hearing impaired. Int J Audiol. 2003;42(3):152–60.CrossRef
19.
Valentijn SA, Van Boxtel MP, Van Hooren SA, Bosma H, Beckers HJ, Ponds RW, et al. Change in sensory functioning predicts change in cognitive functioning: results from a 6-year follow-up in the Maastricht Aging Study. J Am Geriatr Soc. 2005;53(3):374–80.CrossRef
20.
Stark P, Hickson L. Outcomes of hearing aid fitting for older people with hearing impairment and their significant others. Int J Audiol. 2004;43(7):390–8.CrossRef
21.
Brewster K, Choi CJ, He X, Kim AH, Golub JS, Brown PJ, et al. Hearing rehabilitative treatment for older adults with comorbid hearing loss and depression: effects on depressive symptoms and executive function. Am J Geriatr Psychiatry. 2021;S1064-7481(21):00434–6.
22.
Adrait A, Perrot X, Nguyen M-F, Gueugnon M, Petitot C, Collet L, et al. Do hearing aids influence behavioral and psychological symptoms of dementia and quality of life in hearing impaired Alzheimer’s disease patients and their caregivers? J Alzheimers Dis. 2017;58(1):109–21.CrossRef
23.
Mondelli MFCG, de Souza PJS. Quality of life in elderly adults before and after hearing aid fitting. Braz J Otorhinolaryngol. 2012;78(3):49–56.CrossRef
24.
Weinstein BE, Sirow LW, Moser S. Relating hearing aid use to social and emotional loneliness in older adults. Am J Audiol. 2016;25(1):54–61.CrossRef
25.
Niemensivu R, Manchaiah V, Roine RP, Kentala E, Sintonen H. Health-related quality of life in adults with hearing impairment before and after hearing-aid rehabilitation in Finland. Int J Audiol. 2015;54(12):967–75.CrossRef
26.
Blustein J, Weinstein BE. Opening the market for lower cost hearing aids: regulatory change can improve the health of older Americans. Am J Public Health. 2016;106(6):1032–5.CrossRef
27.
Orji A, Kamenov K, Dirac M, Davis A, Chadha S, Vos T. Global and regional needs, unmet needs and access to hearing aids. Int J Audiol. 2020;59(3):166–72.CrossRef
28.
Ye X, Zhu D, Chen S, Shi X, Gong R, Wang J, et al. Impact and cost-effectiveness evaluation of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss: study protocol for a randomized controlled trial. Trials. 2021;22(1):1–9.CrossRef
29.
He P, Wen X, Hu X, Gong R, Luo Y, Guo C, et al. Hearing aid acquisition in Chinese older adults with hearing loss. Am J Public Health. 2018;108(2):241–7.CrossRef
30.
Wilson BS, Tucci DL, Merson MH, O’Donoghue GM. Global hearing health care: new findings and perspectives. Lancet. 2017;390(10111):2503–15.CrossRef
31.
Schoenborn CA, Heyman K. Health disparities among adults with hearing loss: United States, 2000-2006. Health E-Stat. 2008;5:1–14.
32.
Xianting H, Zhiwu H, Jianyong C, Ling M, Yun L, Yan R, et al. HHIE-S scale for hearing screening in the elderly population. J Audiol Speech Pathol. 2014;6:230–4.
33.
Sirgy MJ, Michalos AC, Ferriss AL, Easterlin RA, Patrick D, Pavot W. The quality-of-life (QOL) research movement: past, present, and future. Soc Indic Res. 2006;76(3):343–466.CrossRef
34.
Carlsson PI, Hjaldahl J, Magnuson A, Ternevall E, Edén M, Skagerstrand A, et al. Severe to profound hearing impairment: quality of life, psychosocial consequences and audiological rehabilitation. Disabil Rehabil. 2015;37(20):1849–56.CrossRef
35.
Chen DS, Genther DJ, Betz J, Lin FR. Association between hearing impairment and self-reported difficulty in physical functioning. J Am Geriatr Soc. 2014;62(5):850–6.CrossRef
36.
Boi R, Racca L, Cavallero A, Carpaneto V, Racca M, Dall’Acqua F, et al. Hearing loss and depressive symptoms in elderly patients. Geriatr Gerontol Int. 2012;12(3):440–5.CrossRef
37.
Acar B, Yurekli MF, Babademez MA, Karabulut H, Karasen RM. Effects of hearing aids on cognitive functions and depressive signs in elderly people. Arch Gerontol Geriatr. 2011;52(3):250–2.CrossRef
38.
Chi I, Yip PS, Chiu HF, Chou KL, Chan KS, Kwan CW, et al. Prevalence of depression and its correlates in Hong Kong’s Chinese older adults. Am J Geriatr Psychiatry. 2005;13(5):409–16.CrossRef
39.
Lubben J, Blozik E, Gillmann G, Iliffe S, von Renteln KW, Beck JC, et al. Performance of an abbreviated version of the Lubben Social Network Scale among three European community-dwelling older adult populations. Gerontologist. 2006;46(4):503–13.CrossRef
40.
Hongtao S, Nan H, Lang L. A study of the micro-effect and mechanism of the carbon emission trading scheme. J Xiamen Univ (Arts & Social Sciences). 2017;01:13–22.
41.
Mulrow CD, Aguilar C, Endicott JE, Tuley MR, Velez R, Charlip WS, et al. Quality-of-life changes and hearing impairment. A randomized trial. Ann Intern Med. 1990;113(3):188–94.CrossRef
42.
Cox R, Hyde M, Gatehouse S, Noble W, Dillon H, Bentler R, et al. Optimal outcome measures, research priorities, and international cooperation. Ear Hear. 2000;21(4 Suppl):106S–15S.CrossRef
43.
Lotfi Y, Mehrkian S, Moossavi A, Faghih-Zadeh S. Quality of life improvement in hearing-impaired elderly people after wearing a hearing aid. Arch Iran Med. 2009;12(4):365–70.PubMed
44.
Shukla A, Harper M, Pedersen E, Goman A, Suen JJ, Price C, et al. Hearing loss, loneliness, and social isolation: a systematic review. Otolaryngol Head Neck Surg. 2020;162(5):622–33.CrossRef
Metadata
Title
Effects of providing free hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China: a randomized controlled trial
Authors
Xin Ye
Dawei Zhu
Siyuan Chen
Xuefeng Shi
Rui Gong
Juncheng Wang
Huibin Zuo
Ping He
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2022
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/s12916-022-02323-2

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