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Open Access 01-12-2021 | Human Papillomavirus | Commentary

Human papillomavirus (HPV) testing for cervical cancer screening in a middle-income country: comment on a large real-world implementation study in China

Authors: Louise T. Thomsen, Susanne K. Kjær

Published in: BMC Medicine | Issue 1/2021

Excerpt

Cervical cancer can effectively be prevented by human papillomavirus (HPV) vaccination and early detection and treatment of precancerous lesions (screening). Nevertheless, cervical cancer remains a global public health problem and an important threat to women’s health worldwide. It is the fourth most common cancer in women with more than 600,000 cases and 342,000 deaths in 2020 [1]. Approximately 90% of cervical cancer deaths occur in low- and middle-income countries, underlining the substantial global inequality in disease burden [1]. In May 2018, the World Health Organization (WHO) called for global action to eliminate cervical cancer as a public health problem [2]. The WHO urged member states to scale up efforts to implement preventive strategies against cervical cancer, including HPV vaccination, screening, and treatment for precancerous lesions and cancer [2]. …

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World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: World Health Organization; 2020.

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Aitken CA, van Agt HME, Siebers AG, van Kemenade FJ, Niesters HGM, Melchers WJG, et al. Introduction of primary screening using high-risk HPV DNA detection in the Dutch cervical cancer screening programme: a population-based cohort study. BMC Med. 2019;17(1):228. https://doi.org/10.1186/s12916-019-1460-0.CrossRefPubMedPubMedCentral

Thomsen LT, Kjaer SK, Munk C, Ornskov D, Waldstrom M. Benefits and potential harms of human papillomavirus (HPV)-based cervical cancer screening: a real-world comparison of HPV testing versus cytology. Acta Obstet Gynecol Scand. 2021;100(3):394–402. https://doi.org/10.1111/aogs.14121.CrossRefPubMed

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10.

Zhao Y, Bao H, Ma L, Song B, Di J, Wang L, Gao Y, Ren W, Wang S, Wang H, Wu J. Real-world effectiveness of primary screening with high-risk human papillomavirus testing in the cervical cancer screening programme in China: a nationwide population-based study. BMC Med, 2021; Accepted manuscript in press.

Title: Human papillomavirus (HPV) testing for cervical cancer screening in a middle-income country: comment on a large real-world implementation study in China
Authors: Louise T. Thomsen
Susanne K. Kjær
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Human Papillomavirus
Colposcopy
Triage
Cervical Cancer
Colposcopy
Cervical Cancer
Published in: BMC Medicine / Issue 1/2021
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/s12916-021-02051-z

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