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Published in: BMC Health Services Research 1/2018

Open Access 01-12-2018 | Research article

Validity of International Classification of Diseases (ICD) coding for dengue infections in hospital discharge records in Malaysia

Authors: Yuan-Liang Woon, Keng-Yee Lee, Siti Fatimah Zahra Mohd Anuar, Pik-Pin Goh, Teck-Onn Lim

Published in: BMC Health Services Research | Issue 1/2018

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Abstract

Background

Hospitalization due to dengue illness is an important measure of dengue morbidity. However, limited studies are based on administrative database because the validity of the diagnosis codes is unknown. We validated the International Classification of Diseases, 10th revision (ICD) diagnosis coding for dengue infections in the Malaysian Ministry of Health’s (MOH) hospital discharge database.

Methods

This validation study involves retrospective review of available hospital discharge records and hand-search medical records for years 2010 and 2013. We randomly selected 3219 hospital discharge records coded with dengue and non-dengue infections as their discharge diagnoses from the national hospital discharge database. We then randomly sampled 216 and 144 records for patients with and without codes for dengue respectively, in keeping with their relative frequency in the MOH database, for chart review. The ICD codes for dengue were validated against lab–based diagnostic standard (NS1 or IgM).

Results

The ICD-10-CM codes for dengue had a sensitivity of 94%, modest specificity of 83%, positive predictive value of 87% and negative predictive value 92%. These results were stable between 2010 and 2013. However, its specificity decreased substantially when patients manifested with bleeding or low platelet count.

Conclusion

The diagnostic performance of the ICD codes for dengue in the MOH’s hospital discharge database is adequate for use in health services research on dengue.
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Literature
2.
go back to reference WHO. Global strategy for dengue prevention and control. Geneva: World Health Organization; 2012. WHO. Global strategy for dengue prevention and control. Geneva: World Health Organization; 2012.
3.
go back to reference Beatty ME, Letson GW, Margolis HS. Estimating the global burden of dengue. Am J Trop Med Hyg. 2009;81(1):231. Beatty ME, Letson GW, Margolis HS. Estimating the global burden of dengue. Am J Trop Med Hyg. 2009;81(1):231.
4.
go back to reference Hotez PJ, Alvarado M, Basa ´ne˜z M-G, Bolliger I, Bourne R, et al. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl Trop Dis. 2014;8:e2865.CrossRefPubMedPubMedCentral Hotez PJ, Alvarado M, Basa ´ne˜z M-G, Bolliger I, Bourne R, et al. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl Trop Dis. 2014;8:e2865.CrossRefPubMedPubMedCentral
7.
go back to reference Mia MS, Begum RA, Er AC, Abidin RD, Pereira JJ. Trends of dengue infections in Malaysia, 2000–2010. Asian Pac J Trop Med. 2013;6:462–6.CrossRefPubMed Mia MS, Begum RA, Er AC, Abidin RD, Pereira JJ. Trends of dengue infections in Malaysia, 2000–2010. Asian Pac J Trop Med. 2013;6:462–6.CrossRefPubMed
10.
go back to reference Anders KL, Nguyet NM, Chau NVV, Hung NT, Thuy TT, Lien LB, Farrar J, Wills B, Hien TT, Simmons CP. Epidemiological factors associated with dengue shock syndrome and mortality in hospitalized dengue patients in ho chi Minh City. Vietnam Am J Trop Med Hyg. 2011;84:127–34.CrossRefPubMed Anders KL, Nguyet NM, Chau NVV, Hung NT, Thuy TT, Lien LB, Farrar J, Wills B, Hien TT, Simmons CP. Epidemiological factors associated with dengue shock syndrome and mortality in hospitalized dengue patients in ho chi Minh City. Vietnam Am J Trop Med Hyg. 2011;84:127–34.CrossRefPubMed
11.
go back to reference Wichmann O, Hongsiriwon S, Bowonwatanuwong C, Chotivanich K, Sukthana Y, Pukrittayakamee S. Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in Chonburi, Thailand. Tropical Med Int Health. 2004;9:1022–9.CrossRef Wichmann O, Hongsiriwon S, Bowonwatanuwong C, Chotivanich K, Sukthana Y, Pukrittayakamee S. Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in Chonburi, Thailand. Tropical Med Int Health. 2004;9:1022–9.CrossRef
12.
go back to reference Kittigul L, Pitakarnjanakul P, Sujirarat D, Siripanichgon K. The differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection. J Clin Virol. 2007;39(2):76–81. Epub 2007 May 15CrossRefPubMed Kittigul L, Pitakarnjanakul P, Sujirarat D, Siripanichgon K. The differences of clinical manifestations and laboratory findings in children and adults with dengue virus infection. J Clin Virol. 2007;39(2):76–81. Epub 2007 May 15CrossRefPubMed
13.
go back to reference Chuang VW, Wong TY, Leung YH, Ma ES, Law YL, Tsang OT, Chan KM, Tsang IH, Que TL, Yung RW, Liu SH. Review of dengue fever cases in Hong Kong during 1998 to 2005. Hong Kong Med J. 2008;14:170–7.PubMed Chuang VW, Wong TY, Leung YH, Ma ES, Law YL, Tsang OT, Chan KM, Tsang IH, Que TL, Yung RW, Liu SH. Review of dengue fever cases in Hong Kong during 1998 to 2005. Hong Kong Med J. 2008;14:170–7.PubMed
14.
go back to reference Wang CC, Lee IK, Su MC, Lin HI, Huang YC, Liu SF, Wu CC, Lin MC. Differences in clinical and laboratory characteristics and disease severity between children and adults with dengue virus infection in Taiwan, 2002. Trans R Soc Trop Med Hyg. 2009;103:871–7.CrossRefPubMed Wang CC, Lee IK, Su MC, Lin HI, Huang YC, Liu SF, Wu CC, Lin MC. Differences in clinical and laboratory characteristics and disease severity between children and adults with dengue virus infection in Taiwan, 2002. Trans R Soc Trop Med Hyg. 2009;103:871–7.CrossRefPubMed
15.
go back to reference Hon KL, Nelson EA. Gender disparity in paediatric hospital admissions. Ann Acad Med Singap. 2006;35:882–8.PubMed Hon KL, Nelson EA. Gender disparity in paediatric hospital admissions. Ann Acad Med Singap. 2006;35:882–8.PubMed
16.
go back to reference Kabra SK, Jain Y, Pandey RM, Madhulika ST, Tripathi P, Broor S, Seth P, Seth V. Dengue haemorrhagic fever in children in the 1996 Delhi epidemic. Trans R Soc Trop Med Hyg. 1999;93:294–8.CrossRefPubMed Kabra SK, Jain Y, Pandey RM, Madhulika ST, Tripathi P, Broor S, Seth P, Seth V. Dengue haemorrhagic fever in children in the 1996 Delhi epidemic. Trans R Soc Trop Med Hyg. 1999;93:294–8.CrossRefPubMed
17.
go back to reference Hammond SN, Balmaseda A, Perez L, Tellez Y, Saborio SI, Mercado JC, Videa E, Rodriguez Y, Perez MA, Cuadra R, Solano S, Rocha J, Idiaquez W, Gonzalez A, Harris E. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg. 2005;73:1063–70.PubMed Hammond SN, Balmaseda A, Perez L, Tellez Y, Saborio SI, Mercado JC, Videa E, Rodriguez Y, Perez MA, Cuadra R, Solano S, Rocha J, Idiaquez W, Gonzalez A, Harris E. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg. 2005;73:1063–70.PubMed
18.
go back to reference Uhart M, Blein C, L’Azou M, Thomas L, Durand L. Costs of dengue in three French territories of the Americas: an analysis of the hospital medical information system (PMSI) database. Eur J Health Econ. 2016;17:497–503.CrossRefPubMed Uhart M, Blein C, L’Azou M, Thomas L, Durand L. Costs of dengue in three French territories of the Americas: an analysis of the hospital medical information system (PMSI) database. Eur J Health Econ. 2016;17:497–503.CrossRefPubMed
19.
go back to reference Peeling RW, Artsob H, Pelegrino JL, Buchy P, Cardosa MJ, Devi S, Enria DA, Farrar J, Gubler DJ, Guzman MG, Halstead SB, Hunsperger E, Kliks S, Margolis HS, Nathanson CM, Nguyen VC, Rizzo N, Vázquez S, Yoksan S. Evaluation of diagnostic tests: dengue. Nat Rev Microbiol. 2010 Dec;8(12 Suppl):S30–8.CrossRefPubMed Peeling RW, Artsob H, Pelegrino JL, Buchy P, Cardosa MJ, Devi S, Enria DA, Farrar J, Gubler DJ, Guzman MG, Halstead SB, Hunsperger E, Kliks S, Margolis HS, Nathanson CM, Nguyen VC, Rizzo N, Vázquez S, Yoksan S. Evaluation of diagnostic tests: dengue. Nat Rev Microbiol. 2010 Dec;8(12 Suppl):S30–8.CrossRefPubMed
20.
go back to reference WHO. Dengue guidelines for diagnosis, treatment, prevention and control. 3rd ed. Geneva: World Health Organization; 2009. WHO. Dengue guidelines for diagnosis, treatment, prevention and control. 3rd ed. Geneva: World Health Organization; 2009.
Metadata
Title
Validity of International Classification of Diseases (ICD) coding for dengue infections in hospital discharge records in Malaysia
Authors
Yuan-Liang Woon
Keng-Yee Lee
Siti Fatimah Zahra Mohd Anuar
Pik-Pin Goh
Teck-Onn Lim
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2018
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-018-3104-z

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