Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
BMC Women's Health
Published in: BMC Women's Health 1/2019

Open Access 01-12-2019 | Infertility | Research article

An investigation of the effects of infertility on Women’s quality of life: a case-control study

Authors: Katayoun Bakhtiyar, Ramin Beiranvand, Arash Ardalan, Farahnaz Changaee, Mohammad Almasian, Afsaneh Badrizadeh, Fatemeh Bastami, Farzad Ebrahimzadeh

Published in: BMC Women's Health | Issue 1/2019

Login to get access

Abstract

Background

Human instinctively desire to have offspring. Infertility can cause painful emotional experiences throughout the life mainly known as quality of life impairment. This study aimed to investigate the impact of infertility on a woman’s quality of life.

Methods

A number of 180 infertile and 540 fertile women participated in this matched case-control study. The cases were selected through a combination of multistage stratified and cluster sampling methods. For each infertile woman three fertile women were randomly selected. The data gathering instrument consisted of demographic variables and the WHOQOL-BREF questionnaire. Data collection was conducted through interview with participants. The multivariate marginal model and SPSS software 21 were used for data analyses with a significance level of 0.05.

Results

The results of the multivariate modeling show infertility can potentially affect various aspects of women’s quality of life such as physical health (p <  0.001), mental health (p <  0.001), social health (p <  0.001) and the total score of quality of life (p <  0.001) significantly.

Conclusion

An infertile woman practice a relatively lower scores in QOL sub-scales of mental, physical and environmental health; while they experience a higher social health score than a fertile woman.
Literature
1.
Khodakarami N, Hashemi S, Sedigh S, Hamidi M, Taheripanah R. The experience of living with infertility: a phenomenological study. The fertility and infertility quarterly. Winder. 2009;10(4):287–97.
2.
3.
4.
Inhorn MC, Patrizio P. Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century. Jhum Reprod Update. 2015;21(4):411–26.CrossRef
5.
Faal Kalhkouran L, Bahrami H, Farokhi NA, Zeraati H, Tarahomi M. The comparison of depressive anxiety between two groups selected from fertile and infertile women of Tehran, Iran. Fertility and Infertility Quarterly Spring. 2011;12(158):162–3.
6.
Dural O, Yasa C, Keyif B, Celiksoy H, Demiral I, Ozgor BY. Effect of infertility on quality of life of women: a validation study of the Turkish FertiQoL. Jhuman Fertility. 2016;19(3):186–91.CrossRef
7.
Cousineau TM, Domar AD. Psychological impact of infertility. Best Pract Res Clin Obstet Gynecol. 2007;21(2):293308.CrossRef
8.
Kamel Remah M. Management of the infertile couple: an evidence-based protocol. J Reprod Biol Endocrinol. 2010;8(1):301–6.
9.
van Balen F, Bos HM. The social and cultural consequences of being childless in poor-resource areas. Facts Views Vis Obgyn. 2009;1(2):106–21.PubMedPubMedCentral
10.
Obi SN, Onah HE, Okafor II. Depression among Nigerian women following pregnancy loss. Int J Gynecol Obstet. 2009;105(1):602.CrossRef
11.
Farrokh Eslamlou HR, Haji Shafiha M, et al. The effect of primary infertility on the quality of life of women of Oroumieh, Iran. Oroumieh Med J. 2014;25(598):604–7.
12.
Maroufizadeh S, Karimi E, Vesali S, Omani SR. Anxiety and depression after failure of assisted reproductive treatment among patients experiencing infertility. Int J Gynaecol Obstet. 2015;130(3):253–6.CrossRef
13.
Maroufizadeh S, Ghaheri A. Amini, and Omani Samani.Psychometric properties of the fertility quality of life instrument in infertile Iranian women. Int J Fertil Steril. 2017;10(4):371–9.PubMed
14.
Bonomi AE, Patrick DL, Bushnell DM, Martin M. Validation of the United States’ version of the world health organization quality of life (WHOQOL) instrument. J Clin Epidemiol. 2000;53:1–12.CrossRef
15.
Aliyeh G, Laya F. Quality of life and its correlates among a group of infertile Iranian women. Med Sci Monit. 2007;13(7):313–7.
16.
Choobfroushzadeh A, Kalantai M, Molavi H. The efficacy of stress management using the cognitive behavioral approach on the quality of life infertile women. Psychology Quarterly. 2013;4:1–9.
17.
Daniluk JC. Keeping your Sexlife alive while Coping with Infertility. J Sex Marital Ther. 2002;71(6):1241–3.
18.
Alaami M, Amanati SS, Hagani H, Ramazanzade F. Factors influencing quality of life among infertility women. IJN. 2009;21(56):27–35.
19.
Nilforooshan P, Latifi Z, Abedi MR, Ahmadi SA. Quality of life and its different domains in fertile and infertile women. J Res Behav Sci. 2006;4(12):70–7.
20.
Nejat SN, Montazeri A, Holakhouei Naeini K, Mohammad K, Majdzadeh SR. The World Health Organization Quality of Life (WHOQOLBREF) questionnaire: translation and validation study of the Iranian version. J Sch Public Health Inst Public Health. 2007;4(4):112.
21.
Liang KY, Zeger S. Longitudinl data analysis using generalized linear models. Biometrica. 1986;73(1):13–22.CrossRef
22.
Bendal RB, Afifi AA. Comparison of stopping rules in forward regression. J Am Stat Assoc. 1977;72:46–53.
23.
Mickey RM, Greenland S. The impact of confounder selection criteria on effect estimation. Am J Epidemiol. 1989;129:125–37.CrossRef
24.
Keramat A, Masoomi SZ, Mousavi SA, Poorolajal J, Shobeiri F, Hazavhei SM. Quality of life and its related factors in infertile couples. J Res Health Sci. 2013;14(1):57–64.
25.
Rashidi B, Montazeri A, Ramezanzadeh F, Shariat M, Abedinia N, Ashrafi M. Health-related quality of life in infertile couples receiving IVF or ICSI treatment. BMC Health Serv Res. 2008;8:186.CrossRef
26.
Martins MV, Peterson BD, Almeida VM, Costa ME. Direct and indirect effects of perceived social support on women’s infertility-related stress. Hum Reprod. 2011;26(8):2113–21.CrossRef
27.
Mirghafourvand M, Mohammad-Alizadeh Charandabi S, Asghari Jafarabadi M, Tavananezhad N, Karkhane M. Predictors of health-related quality of life in Iranian women of reproductive age. Appl Res Qual Life. 2016;11(3):723–37.CrossRef
28.
Asadian A, Aghamolaei T, Zare F, Khodarahmi M, Ghanbarnejad A, Zainali M, Ashough M. Quality of life in pregnant women in Bandar Abbas, South Iran. J Biol Today’s World. 2014;3(8):180–4.
29.
Fallahzadeh H, Mirzaei H. Health-related quality of life and associated factors among Iranian university students. J Commun Health Res. 2012;1(2):122–30.
30.
Nejat S, Montazeri A, Holakouie K, Mohammad K, Majdzadeh R. Quality of Life of Tehran's Population by WHOQOL-BREF questionnaire in 2005. Hakim Res J. 2007;10(3):1–8.
31.
Paksoy Erbaydar N, Bilir N, Hilal Özcebe L, Vaizoğlu S, Aslan D. Evaluation of health-related quality of life of women living in a city center in the east of Turkey. Turkish J Med Sci. 2011;41(2):307–16.
32.
Hopman WM, Berger C, Joseph L, Towheed T, Prior JC, Anastassiades T, Poliquin S, Zhou W, Adachi JD, Hanley DA, Papadimitropoulos EA, Tenenhouse A, CaMos Research Group. Health-related quality of life I n Canadian adolescents and young adults: normative data using the SF-36. Can J Public Health. 2009;100(6):449–52.PubMedPubMedCentral
33.
Rezaei N, Azadi A, Zargousi R, Sadoughi Z, Tavalaee Z, Rezayati M. Maternal health-related quality of life and its predicting factors in the postpartum period in Iran. J Scientifica. 2016;2016:8542147.
34.
Rostami A, Ghazinour L, Nygren L, Nojumi M, Richter J. Health-related Quality of Life, Marital Satisfaction, and Social Support in Medical Staff in Iran. Appl Res Qual Life. 2013;8(3):385–402.CrossRef
35.
Dancet EA, Nelen WL, Sermeus W, De Leeuw L, Kremer JA, D'Hooghe TM. The patients' perspective on fertility care: a systematic review. Hum Reprod Update. 2010;16(5):467–87.CrossRef
36.
Wang P, Liou SR, Cheng CY. Prediction of maternal quality of life on preterm birth and low birthweight: a longitudinal study. BMC Pregnancy and Childbirth. 2013;13:124.CrossRef
37.
Ibrahim MAH, Taher AER, Ahmed YS. Primary infertility and health related quality of life upper Egypt. Int J Gynaecol Obstet. 2010;110(2):118–21.CrossRef
38.
Chachamovich JR, Chachamovich E, Ezer H, Fleck MP, Knauth D, Passos EP. Investigating quality of life and health-related quality of life in infertility: a systematic review. J Psychosom Obstet Gynaecol. 2010;31(2):101–10.CrossRef
39.
Bahrami N, Karimian Z, Bahrami S, Bolbolhaghighi N. Comparing the postpartum quality of life between six to eight weeks and twelve to fourteen weeks after delivery in Iran. Iran Red Crescent Med J. 2014;16(7):1–5.CrossRef
40.
Keshavarzi S, Ayatollahi SMT, Zare N, Sharif F. Quality of life of childbearing age women and its associated factors: an application of seemingly unrelated regression (SUR) models. Qual Life Res. 2013;22(6):1255–63.CrossRef
41.
Rimaz SH, Dastoorpoor M, Vesali S, Saiepour N, Beigi Z, Nedjat S. The Survey of Quality of Life and its Related Factors in Female –headed Households Supported by Tehran Municipality,Ddistrict 9. Iran J Epidemiol. 2014;10(2):48–55.
42.
Pujols Y, Meston CM, Seal BN. The association between sexual satisfaction and body image in women. J Sex Med. 2010;7(2pt2):905–16.CrossRef
43.
Meltzer AL, McNulty JK. Body image and marital satisfaction: evidence for the mediating role of sexual frequency and sexual satisfaction. J Fam Psychol. 2010;24(2):156–64.CrossRef
44.
Lau JT, Wang Q, Cheng Y, Kim JH, Yang X, Tsui HY. Infertility-related perceptions and responses and their associations with quality of life among rural Chinese infertile couples. J Sex Marital Ther. 2008;34(3):248–67.CrossRef
45.
Martins MV, Peterson BD, Costa ME, Lund R, Schmid TL. Infertility disclosure moderates the relationship between social support and fertility stress in patients following unsuccessful treatments. Hum Reprod. 2012;27(Suppl 2):ii98–ii100.CrossRef
46.
Proulx CM, Helms HM, Buehler C. Marital quality and personal well-being: a meta-analysis. J Marriage Fam. 2007;69(3):576–93.CrossRef
Metadata
Title
An investigation of the effects of infertility on Women’s quality of life: a case-control study
Authors
Katayoun Bakhtiyar
Ramin Beiranvand
Arash Ardalan
Farahnaz Changaee
Mohammad Almasian
Afsaneh Badrizadeh
Fatemeh Bastami
Farzad Ebrahimzadeh
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2019
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-019-0805-3

Other articles of this Issue 1/2019

BMC Women's Health 1/2019 Go to the issue

Research article

Validation of the Pelvic Organ Prolapse Simple Screening Inventory (POPSSI) in a population of Ethiopian women

Research article

Cesarean scar endometriosis: presentation of 198 cases and literature review

Study protocol

A combination intervention addressing sexual risk-taking behaviors among vulnerable women in Uganda: study protocol for a cluster randomized clinical trial

Research article

Perspectives of women participating in a cervical cancer screening campaign with community-based HPV self-sampling in rural western Kenya: a qualitative study

Research article

The effect of a savings intervention on women’s intimate partner violence victimization: heterogeneous findings from a randomized controlled trial in Colombia

Case report

Spontaneous regression of quiescent gestational trophoblastic disease after pregnancy: a case report