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Published in: BMC Women's Health 1/2018

Open Access 01-12-2018 | Research article

Polycystic ovary syndrome and its impact on Iranian women’s quality of life: a population-based study

Authors: Zahra Behboodi Moghadam, Bita Fereidooni, Mohsen Saffari, Ali Montazeri

Published in: BMC Women's Health | Issue 1/2018

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Abstract

Background

Polycystic ovary syndrome (PCOS) is a major public health concern worldwide affecting up to one in five women at reproductive age. It is associated with biochemical and hormonal disturbances as well as adverse cosmetic, reproductive, metabolic, and psychological consequences, resulting in worsened quality of life. The aim of the present study is evaluating the quality of life and determining its degrading factors among Iranian women suffering from this syndrome.

Methods

This cross-sectional study was conducted on 200 PCOS women in Hamadan, Iran. In order to measure quality of life we used the Persian version of Health-related Quality of Life Questionnaire for PCOS (PCOSQ). Descriptive statistics was used to explore the data. In addition linear regression analysis was performed to assess factors affecting health-related quality of life in this population.

Results

The mean score for quality of life domains (from the greatest to the least serious concern) were: infertility (3.43 ± 1.63), emotions (3.55 ± 1.17), menstrual problems (3.77 ± 1.36), body hair (3.80 ± 2.05) and weight (4.32 ± 1.80), respectively. The higher score represents better function. However, multivariate analysis revealed that hirsutism had the strongest impact on the patients’ quality of life (p < 0.001) followed by infertility (p = 0.038) and menstrual irregularity (p = 0.003).

Conclusion

The findings showed that impairment of quality of life was associated with PCOS related conditions such as hirsutism, infertility and menstrual problems.
Literature
1.
go back to reference Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, et al. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-sponsored 3rd PCOS consensus workshop group. Fertil Steril. 2012;97(1):28–38.CrossRef Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, et al. Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-sponsored 3rd PCOS consensus workshop group. Fertil Steril. 2012;97(1):28–38.CrossRef
2.
go back to reference Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–P29.CrossRef Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–P29.CrossRef
3.
go back to reference Tehrani FR, Simbar M, Tohidi M, Hosseinpanah F, Azizi F. The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reprod Biol Endocrinol. 2011;9(39):39.CrossRef Tehrani FR, Simbar M, Tohidi M, Hosseinpanah F, Azizi F. The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reprod Biol Endocrinol. 2011;9(39):39.CrossRef
4.
go back to reference Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;8(1):41.CrossRef Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;8(1):41.CrossRef
5.
go back to reference McCook JG, Reame NE, Thatcher SS. Health-related quality of life issues in women with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2005;34(1):12–20.CrossRef McCook JG, Reame NE, Thatcher SS. Health-related quality of life issues in women with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2005;34(1):12–20.CrossRef
6.
go back to reference Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr Rev. 2015;36(5):487–525.CrossRef Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr Rev. 2015;36(5):487–525.CrossRef
7.
go back to reference Rotterdam E, ASRM-Sponsored P. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41.CrossRef Rotterdam E, ASRM-Sponsored P. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41.CrossRef
8.
go back to reference Azziz R, Marin C, Hoq L, Badamgarav E, Song P. Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. J Clin Endocrinol Metab. 2005;90(8):4650–8.CrossRef Azziz R, Marin C, Hoq L, Badamgarav E, Song P. Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. J Clin Endocrinol Metab. 2005;90(8):4650–8.CrossRef
9.
go back to reference Hart R, Doherty DA. The potential implications of a PCOS diagnosis on a woman's long-term health using data linkage. J Clin Endocrinol Metab. 2014;100(3):911–9.CrossRef Hart R, Doherty DA. The potential implications of a PCOS diagnosis on a woman's long-term health using data linkage. J Clin Endocrinol Metab. 2014;100(3):911–9.CrossRef
10.
go back to reference Puurunen J, Piltonen T, Morin-Papunen L, Perheentupa A, Järvelä I, Ruokonen A, Tapanainen JS. Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS. J Clin Endocrinol Metab. 2011;96(6):1827–34.CrossRef Puurunen J, Piltonen T, Morin-Papunen L, Perheentupa A, Järvelä I, Ruokonen A, Tapanainen JS. Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS. J Clin Endocrinol Metab. 2011;96(6):1827–34.CrossRef
11.
go back to reference Torpy JM, Lynm C, Glass RM. Polycystic ovary syndrome. JAMA. 2007;297(5):554.CrossRef Torpy JM, Lynm C, Glass RM. Polycystic ovary syndrome. JAMA. 2007;297(5):554.CrossRef
12.
go back to reference Moran LJ, Norman RJ, Teede HJ. Metabolic risk in PCOS: phenotype and adiposity impact. Trends Endocrinol Metab. 2015;26(3):136–43.CrossRef Moran LJ, Norman RJ, Teede HJ. Metabolic risk in PCOS: phenotype and adiposity impact. Trends Endocrinol Metab. 2015;26(3):136–43.CrossRef
13.
go back to reference Veltman-Verhulst SM, Boivin J, Eijkemans MJ, Fauser BJ. Emotional distress is a common risk in women with polycystic ovary syndrome: a systematic review and meta-analysis of 28 studies. Hum Reprod Update. 2012;18(6):638–51.CrossRef Veltman-Verhulst SM, Boivin J, Eijkemans MJ, Fauser BJ. Emotional distress is a common risk in women with polycystic ovary syndrome: a systematic review and meta-analysis of 28 studies. Hum Reprod Update. 2012;18(6):638–51.CrossRef
14.
go back to reference Blay SL, Aguiar JV, Passos IC. Polycystic ovary syndrome and mental disorders: a systematic review and exploratory meta-analysis. Neuropsychiatr Dis Treat. 2016;12:2895–903.CrossRef Blay SL, Aguiar JV, Passos IC. Polycystic ovary syndrome and mental disorders: a systematic review and exploratory meta-analysis. Neuropsychiatr Dis Treat. 2016;12:2895–903.CrossRef
15.
go back to reference Drosdzol A, Skrzypulec V, Mazur B, Pawlinska-Chmara R. Quality of life and marital sexual satisfaction in women with polycystic ovary syndrome. Folia Histochem Cytobiol. 2007;45(Suppl 1):S93–7.PubMed Drosdzol A, Skrzypulec V, Mazur B, Pawlinska-Chmara R. Quality of life and marital sexual satisfaction in women with polycystic ovary syndrome. Folia Histochem Cytobiol. 2007;45(Suppl 1):S93–7.PubMed
16.
go back to reference Lee I, Cooney LG, Saini S, Smith ME, Sammel MD, Allison KC, Dokras A. Increased risk of disordered eating in polycystic ovary syndrome. Fertil Steril. 2017;107(3):796–802.CrossRef Lee I, Cooney LG, Saini S, Smith ME, Sammel MD, Allison KC, Dokras A. Increased risk of disordered eating in polycystic ovary syndrome. Fertil Steril. 2017;107(3):796–802.CrossRef
17.
go back to reference Ekbäck M, Wijma K, Benzein E. “It is always on my mind”: Women's experiences of their bodies when living with hirsutism. Health Care Women Int. 2009;30(5):358–72.CrossRef Ekbäck M, Wijma K, Benzein E. “It is always on my mind”: Women's experiences of their bodies when living with hirsutism. Health Care Women Int. 2009;30(5):358–72.CrossRef
18.
go back to reference Balikci A, Erdem M, Keskin U, Bozkurt Zincir S, Gulsun M, Ozcelik F, Akgul EO, Akarsu S, Oztosun M, Ergun A. Depression, anxiety, and anger in patients with polycystic ovary syndrome. Noro Psikiyatr Ars. 2014;51(4):328–33.PubMedPubMedCentral Balikci A, Erdem M, Keskin U, Bozkurt Zincir S, Gulsun M, Ozcelik F, Akgul EO, Akarsu S, Oztosun M, Ergun A. Depression, anxiety, and anger in patients with polycystic ovary syndrome. Noro Psikiyatr Ars. 2014;51(4):328–33.PubMedPubMedCentral
19.
go back to reference Jones G, Hall J, Balen A, Ledger W. Health-related quality of life measurement in women with polycystic ovary syndrome: a systematic review. Hum Reprod Update. 2008;14(1):15–25.CrossRef Jones G, Hall J, Balen A, Ledger W. Health-related quality of life measurement in women with polycystic ovary syndrome: a systematic review. Hum Reprod Update. 2008;14(1):15–25.CrossRef
20.
go back to reference Li Y, Ng EHY, Stener-Victorin E, Hou L, Wu T, Han F, Wu X. Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis. Fertil Steril. 2011;96(2):452–8.CrossRef Li Y, Ng EHY, Stener-Victorin E, Hou L, Wu T, Han F, Wu X. Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis. Fertil Steril. 2011;96(2):452–8.CrossRef
21.
go back to reference Kaczmarek C, Haller DM, Yaron M. Health related quality of life in adolescents and young adults with polycystic ovary syndrome: a systematic review. J Pediatr Adolesc Gynecol. 2016;29(6):551–7.CrossRef Kaczmarek C, Haller DM, Yaron M. Health related quality of life in adolescents and young adults with polycystic ovary syndrome: a systematic review. J Pediatr Adolesc Gynecol. 2016;29(6):551–7.CrossRef
22.
go back to reference Ching HL, Burke V, Stuckey BG. Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers. Clin Endocrinol. 2007;66(3):373–9.CrossRef Ching HL, Burke V, Stuckey BG. Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers. Clin Endocrinol. 2007;66(3):373–9.CrossRef
23.
go back to reference Panico A, Messina G, Lupoli GA, Lupoli R, Cacciapuoti M, Moscatelli F, Esposito T, Villano I, Valenzano A, Monda V. Quality of life in overweight (obese) and normal-weight women with polycystic ovary syndrome. Patient Prefer Adherence. 2017;11:423.CrossRef Panico A, Messina G, Lupoli GA, Lupoli R, Cacciapuoti M, Moscatelli F, Esposito T, Villano I, Valenzano A, Monda V. Quality of life in overweight (obese) and normal-weight women with polycystic ovary syndrome. Patient Prefer Adherence. 2017;11:423.CrossRef
24.
go back to reference Colwell HH, Mathias SD, Pasta DJ, Henning JM, Steege JF. A health-related quality-of-life instrument for symptomatic patients with endometriosis: a validation study. Am J Obstet Gynecol. 1998;179(1):47–55.CrossRef Colwell HH, Mathias SD, Pasta DJ, Henning JM, Steege JF. A health-related quality-of-life instrument for symptomatic patients with endometriosis: a validation study. Am J Obstet Gynecol. 1998;179(1):47–55.CrossRef
25.
go back to reference Pulman A. A patient centred framework for improving LTC quality of life through web 2.0 technology. Health Informatics J. 2010;16(1):15–23.CrossRef Pulman A. A patient centred framework for improving LTC quality of life through web 2.0 technology. Health Informatics J. 2010;16(1):15–23.CrossRef
26.
go back to reference Stracquadanio M, Ciotta L. Metabolic Aspects of PCOS: Treatment With Insulin Sensitizers. Switzerland: Springer; 2015.CrossRef Stracquadanio M, Ciotta L. Metabolic Aspects of PCOS: Treatment With Insulin Sensitizers. Switzerland: Springer; 2015.CrossRef
27.
go back to reference Boyle JA, Cunningham J, O'Dea K, Dunbar T, Norman RJ. Prevalence of polycystic ovary syndrome in a sample of indigenous women in Darwin, Australia. Med J Aust. 2012;196(1):62–6.CrossRef Boyle JA, Cunningham J, O'Dea K, Dunbar T, Norman RJ. Prevalence of polycystic ovary syndrome in a sample of indigenous women in Darwin, Australia. Med J Aust. 2012;196(1):62–6.CrossRef
28.
go back to reference Wijeyaratne CN, Dilini Udayangani S, Balen AH. Ethnic-specific polycystic ovary syndrome: epidemiology, significance and implications. Expert Rev Endocrinol Metab. 2013;8(1):71–9.CrossRef Wijeyaratne CN, Dilini Udayangani S, Balen AH. Ethnic-specific polycystic ovary syndrome: epidemiology, significance and implications. Expert Rev Endocrinol Metab. 2013;8(1):71–9.CrossRef
29.
go back to reference Schmid J, Kirchengast S, Vytiska-Binstorfer E, Huber J. Infertility caused by PCOS—health-related quality of life among Austrian and Moslem immigrant women in Austria. Hum Reprod. 2004;19(10):2251–7.CrossRef Schmid J, Kirchengast S, Vytiska-Binstorfer E, Huber J. Infertility caused by PCOS—health-related quality of life among Austrian and Moslem immigrant women in Austria. Hum Reprod. 2004;19(10):2251–7.CrossRef
30.
go back to reference Elsenbruch S, Hahn S, Kowalsky D, Öffner AH, Schedlowski M, Mann K, Janssen OE. Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2003;88(12):5801–7.CrossRef Elsenbruch S, Hahn S, Kowalsky D, Öffner AH, Schedlowski M, Mann K, Janssen OE. Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2003;88(12):5801–7.CrossRef
32.
go back to reference Elsenbruch S, Benson S, Hahn S, Tan S, Mann K, Pleger K, Kimmig R, Janssen OE. Determinants of emotional distress in women with polycystic ovary syndrome. Hum Reprod. 2006;21(4):1092–9.CrossRef Elsenbruch S, Benson S, Hahn S, Tan S, Mann K, Pleger K, Kimmig R, Janssen OE. Determinants of emotional distress in women with polycystic ovary syndrome. Hum Reprod. 2006;21(4):1092–9.CrossRef
33.
go back to reference Kitzinger C, Willmott J. ‘The thief of womanhood’: women's experience of polycystic ovarian syndrome. Soc Sci Med. 2002;54(3):349–61.CrossRef Kitzinger C, Willmott J. ‘The thief of womanhood’: women's experience of polycystic ovarian syndrome. Soc Sci Med. 2002;54(3):349–61.CrossRef
34.
go back to reference Tan S, Hahn S, Benson S, Janssen O, Dietz T, Kimmig R, Hesse-Hussain J, Mann K, Schedlowski M, Arck P. Psychological implications of infertility in women with polycystic ovary syndrome. Hum Reprod. 2008;23(9):2064–71.CrossRef Tan S, Hahn S, Benson S, Janssen O, Dietz T, Kimmig R, Hesse-Hussain J, Mann K, Schedlowski M, Arck P. Psychological implications of infertility in women with polycystic ovary syndrome. Hum Reprod. 2008;23(9):2064–71.CrossRef
35.
go back to reference Taghavi SA, Bazarganipour F, Hugh-Jones S, Hosseini N. Health-related quality of life in Iranian women with polycystic ovary syndrome: a qualitative study. BMC Womens Health. 2015;15(1):1.CrossRef Taghavi SA, Bazarganipour F, Hugh-Jones S, Hosseini N. Health-related quality of life in Iranian women with polycystic ovary syndrome: a qualitative study. BMC Womens Health. 2015;15(1):1.CrossRef
36.
go back to reference Snyder BS. The lived experience of women diagnosed with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2006;35(3):385–92.CrossRef Snyder BS. The lived experience of women diagnosed with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2006;35(3):385–92.CrossRef
37.
go back to reference Brady C, Mousa SS, Mousa SA. Polycystic ovary syndrome and its impact on women's quality of life: more than just an endocrine disorder. Drug Healthc Patient Saf. 2009;1:9–15.PubMedPubMedCentral Brady C, Mousa SS, Mousa SA. Polycystic ovary syndrome and its impact on women's quality of life: more than just an endocrine disorder. Drug Healthc Patient Saf. 2009;1:9–15.PubMedPubMedCentral
38.
go back to reference Jones GL, Hall JM, Lashen HL, Balen AH, Ledger WL. Health-related quality of life among adolescents with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2011;40(5):577–88.CrossRef Jones GL, Hall JM, Lashen HL, Balen AH, Ledger WL. Health-related quality of life among adolescents with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs. 2011;40(5):577–88.CrossRef
39.
go back to reference Ferriman D, Gallwey J. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 1961;21(11):1440–7.CrossRef Ferriman D, Gallwey J. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 1961;21(11):1440–7.CrossRef
40.
go back to reference Bolognia JL, Jorizzo JL, Schaffer J. Dermatology: 2-volume set: expert consult premium edition-enhanced online features and print. Philadelphia: Saunders; 2012. Bolognia JL, Jorizzo JL, Schaffer J. Dermatology: 2-volume set: expert consult premium edition-enhanced online features and print. Philadelphia: Saunders; 2012.
41.
go back to reference Cronin L, Guyatt G, Griffith L, Wong E, Azziz R, Futterweit W, Cook D, Dunaif A. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab. 1998;83(6):1976–87.PubMed Cronin L, Guyatt G, Griffith L, Wong E, Azziz R, Futterweit W, Cook D, Dunaif A. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab. 1998;83(6):1976–87.PubMed
42.
go back to reference Amini L, Montazeri A. Iranian version of polycystic ovarian syndrome health related quality of life questionnaire (PCOSQ): translation, validity and reliability. Payesh J. 2011;11:213–9. Amini L, Montazeri A. Iranian version of polycystic ovarian syndrome health related quality of life questionnaire (PCOSQ): translation, validity and reliability. Payesh J. 2011;11:213–9.
43.
go back to reference Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Faghihzadeh S. Iranian version of modified polycystic ovary syndrome health-related quality of life questionnaire: discriminant and convergent validity. Iran J Reprod Med. 2013;11(9):753.PubMedPubMedCentral Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Faghihzadeh S. Iranian version of modified polycystic ovary syndrome health-related quality of life questionnaire: discriminant and convergent validity. Iran J Reprod Med. 2013;11(9):753.PubMedPubMedCentral
44.
go back to reference Kumarapeli V, Seneviratne RA, Wijeyaratne C. Health-related quality of life and psychological distress in polycystic ovary syndrome: a hidden facet in south Asian women. BJOG Int J Obstet Gynaecol. 2011;118(3):319–28.CrossRef Kumarapeli V, Seneviratne RA, Wijeyaratne C. Health-related quality of life and psychological distress in polycystic ovary syndrome: a hidden facet in south Asian women. BJOG Int J Obstet Gynaecol. 2011;118(3):319–28.CrossRef
45.
go back to reference Khomami MB, Tehrani FR, Hashemi S, Farahmand M, Azizi F. Of PCOS symptoms, hirsutism has the most significant impact on the quality of life of Iranian women. PLoS One. 2015;10(4):e0123608.CrossRef Khomami MB, Tehrani FR, Hashemi S, Farahmand M, Azizi F. Of PCOS symptoms, hirsutism has the most significant impact on the quality of life of Iranian women. PLoS One. 2015;10(4):e0123608.CrossRef
46.
go back to reference Kaliarnta S, Nihlen-Fahlquist J, Roeser S. Emotions and ethical considerations of women undergoing IVF-treatments. HEC Forum. 2011;23(4):281–93.CrossRef Kaliarnta S, Nihlen-Fahlquist J, Roeser S. Emotions and ethical considerations of women undergoing IVF-treatments. HEC Forum. 2011;23(4):281–93.CrossRef
47.
go back to reference Thomas SA, Aw F. A review of the impact of body image on quality of life in women with polycystic ovary syndrome. Int J Psychol Res. 2014;9(1):17. Thomas SA, Aw F. A review of the impact of body image on quality of life in women with polycystic ovary syndrome. Int J Psychol Res. 2014;9(1):17.
48.
go back to reference Hahn S, Janssen OE, Tan S, Pleger K, Mann K, Schedlowski M, Kimmig R, Benson S, Balamitsa E, Elsenbruch S. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol. 2005;153(6):853–60.CrossRef Hahn S, Janssen OE, Tan S, Pleger K, Mann K, Schedlowski M, Kimmig R, Benson S, Balamitsa E, Elsenbruch S. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol. 2005;153(6):853–60.CrossRef
49.
go back to reference Moran LJ, Deeks AA, Gibson-Helm ME, Teede HJ. Psychological parameters in the reproductive phenotypes of polycystic ovary syndrome. Hum Reprod. 2012;27(7):2082–8.CrossRef Moran LJ, Deeks AA, Gibson-Helm ME, Teede HJ. Psychological parameters in the reproductive phenotypes of polycystic ovary syndrome. Hum Reprod. 2012;27(7):2082–8.CrossRef
50.
go back to reference Ridenour AF, Yorgason JB, Peterson B. The infertility resilience model: assessing individual, couple, and external predictive factors. Contemp Fam Ther. 2009;31(1):34–51.CrossRef Ridenour AF, Yorgason JB, Peterson B. The infertility resilience model: assessing individual, couple, and external predictive factors. Contemp Fam Ther. 2009;31(1):34–51.CrossRef
51.
go back to reference Santoro N, Eisenberg E, Trussell JC, Craig LB, Gracia C, Huang H, Alvero R, Casson P, Christman G, Coutifaris C, et al. Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome. Hum Reprod. 2016;31(10):2268–79.CrossRef Santoro N, Eisenberg E, Trussell JC, Craig LB, Gracia C, Huang H, Alvero R, Casson P, Christman G, Coutifaris C, et al. Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome. Hum Reprod. 2016;31(10):2268–79.CrossRef
52.
go back to reference Whiteford LM, Gonzalez L. Stigma: the hidden burden of infertility. Soc Sci Med. 1995;40(1):27–36.CrossRef Whiteford LM, Gonzalez L. Stigma: the hidden burden of infertility. Soc Sci Med. 1995;40(1):27–36.CrossRef
53.
go back to reference Becker G, Nachtigall RD. Eager for medicalisation: the social production of infertility as a disease. Sociol Health Illn. 1992;14(4):456–71.CrossRef Becker G, Nachtigall RD. Eager for medicalisation: the social production of infertility as a disease. Sociol Health Illn. 1992;14(4):456–71.CrossRef
54.
go back to reference Malin M, Hemminki E. What do women want? Women's experiences of infertility treatment. Soc Sci Med. 2001;53:123–33.CrossRef Malin M, Hemminki E. What do women want? Women's experiences of infertility treatment. Soc Sci Med. 2001;53:123–33.CrossRef
55.
go back to reference Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Kazemnejad A, Faghihzadeh S. Predictive factors of health-related quality of life in patients with polycystic ovary syndrome: a structural equation modeling approach. Fertil Steril. 2013;100(5):1389–96.CrossRef Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Kazemnejad A, Faghihzadeh S. Predictive factors of health-related quality of life in patients with polycystic ovary syndrome: a structural equation modeling approach. Fertil Steril. 2013;100(5):1389–96.CrossRef
56.
go back to reference Mani H, Chudasama Y, Hadjiconstantinou M, Bodicoat DH, Edwardson C, Levy MJ, Gray LJ, Barnett J, Daly H, Howlett TA. Structured education programme for women with polycystic ovary syndrome: a randomised controlled trial. Endocr Connect. 2018;7(1):26–35.CrossRef Mani H, Chudasama Y, Hadjiconstantinou M, Bodicoat DH, Edwardson C, Levy MJ, Gray LJ, Barnett J, Daly H, Howlett TA. Structured education programme for women with polycystic ovary syndrome: a randomised controlled trial. Endocr Connect. 2018;7(1):26–35.CrossRef
57.
go back to reference Brown PJ. Culture and the evolution of obesity. Hum Nat. 1991;2(1):31–57.CrossRef Brown PJ. Culture and the evolution of obesity. Hum Nat. 1991;2(1):31–57.CrossRef
58.
go back to reference Hashimoto DM, Schmid J, Martins FM, Fonseca AM, Andrade LH, Kirchengast S, Eggers S. The impact of the weight status on subjective symptomatology of the polycystic ovary syndrome: a cross-cultural comparison between Brazilian and Austrian women. Anthropol Anz. 2003;61(3):297–310.PubMed Hashimoto DM, Schmid J, Martins FM, Fonseca AM, Andrade LH, Kirchengast S, Eggers S. The impact of the weight status on subjective symptomatology of the polycystic ovary syndrome: a cross-cultural comparison between Brazilian and Austrian women. Anthropol Anz. 2003;61(3):297–310.PubMed
59.
go back to reference Barnard L, Ferriday D, Guenther N, Strauss B, Balen A, Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Hum Reprod. 2007;22(8):2279–86.CrossRef Barnard L, Ferriday D, Guenther N, Strauss B, Balen A, Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Hum Reprod. 2007;22(8):2279–86.CrossRef
60.
go back to reference McCook JG, Bailey BA, Williams SL, Anand S, Reame NE. Differential contributions of polycystic ovary syndrome (PCOS) manifestations to psychological symptoms. J Behav Health Serv Res. 2015;42(3):383–94.CrossRef McCook JG, Bailey BA, Williams SL, Anand S, Reame NE. Differential contributions of polycystic ovary syndrome (PCOS) manifestations to psychological symptoms. J Behav Health Serv Res. 2015;42(3):383–94.CrossRef
Metadata
Title
Polycystic ovary syndrome and its impact on Iranian women’s quality of life: a population-based study
Authors
Zahra Behboodi Moghadam
Bita Fereidooni
Mohsen Saffari
Ali Montazeri
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2018
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-018-0658-1

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