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Published in: BMC Palliative Care 1/2018

Open Access 01-12-2018 | Research article

Chemotherapy and palliative care near end-of life: examining the appropriateness at a cancer institute for colorectal cancer patients

Authors: Ilaria Massa, Oriana Nanni, Flavia Foca, Marco Maltoni, Stefania Derni, Nicola Gentili, Giovanni Luca Frassineti, Andrea Casadei Gardini, Martina Valgiusti, Dino Amadori, Elena Prati, Mattia Altini, Davide Gallegati, Elisabetta Sansoni

Published in: BMC Palliative Care | Issue 1/2018

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Abstract

Background

Appropriate cessation of chemotherapy and timely referral of patients to hospice services are crucial for the quality of care near death. We investigated the quality of care in our Cancer Institute in very advanced metastatic colorectal cancer patients treated in real life.

Patients and Methods

We performed a retrospective analysis of electronic medical data of patients with metastatic colorectal cancer who were candidates for chemotherapy during the study period (1 January 2007–30 June 2014) and died before 31 December 2014. Quality-of-cancer-care indicators were calculated for the overuse of chemotherapy and referral to hospice. Predictive factors of chemotherapy discontinuation and hospice referral in end-of life care were investigated using parametric and nonparametric methods.

Results

Of the 365 patients who died before 31 December 2014, 26 (7.1%) received chemotherapy in the last 14 days of life and 36 (9.8%) started a new chemotherapy regimen in the last 30 days of life. Factors associated with the overuse of chemotherapy were being < 70 years of age for both indicators and not having received advanced chemotherapy treatments for the former indicator. The majority of patients (74.7%) had access to hospice services, of whom only a small percentage (7.2%) accessed them very near to death.

Conclusions

According to the criteria used, our Institute provides a good quality of cancer care for dying colorectal cancer patients, measured by the use of chemotherapy and referral to hospice in their last days of life.
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Metadata
Title
Chemotherapy and palliative care near end-of life: examining the appropriateness at a cancer institute for colorectal cancer patients
Authors
Ilaria Massa
Oriana Nanni
Flavia Foca
Marco Maltoni
Stefania Derni
Nicola Gentili
Giovanni Luca Frassineti
Andrea Casadei Gardini
Martina Valgiusti
Dino Amadori
Elena Prati
Mattia Altini
Davide Gallegati
Elisabetta Sansoni
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Palliative Care / Issue 1/2018
Electronic ISSN: 1472-684X
DOI
https://doi.org/10.1186/s12904-018-0339-8

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