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BMC Oral Health
Published in: BMC Oral Health 1/2022

Open Access 01-12-2022 | Orthopantomogram | Case report

Granular cell odontogenic tumor: report of a rare case and a review of literature

Authors: Milad Etemadi Sh, Sayed Mohammad Razavi, Olia Ghazavi, Mohammad Hossein Nikbakht

Published in: BMC Oral Health | Issue 1/2022

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Abstract

Background

Granular cell odontogenic tumor (GCOT) is a rare neoplasm with about 45 cases reported in the literature. It usually occurs in the posterior mandible of middle-aged women.

Case presentation

We report a case of asymptomatic GCOT in the posterior mandible of a 28 years old female and provide a literature review of GCOT cases. Some unusual features such as root resorption, displacement of inferior tooth canal, and multilocular appearance were considerable in this case.

Conclusions

Complete surgical excision of the lesion was beneficial for the patient.
Literature
1.
Sarode SC, Sarode GS, Vaidya K. Central granular cell odontogenic tumor: a systematic review. J Oral Pathol Med. 2014;43:167–76.CrossRef
2.
Werthemann A. Uber spongiocytares adamantinoma. Oncologie. 1950;3:193–207.CrossRef
3.
Meer S, Altini M, Coleman H, Daya N. Central granular cell odontogenic tumor: immunohistochemistry and ultrastructure. Am J Otolaryngol. 2004;25:73–8.CrossRef
4.
Brannon RB, Goode RK, Eversole LR, Carr RF. The central granular cell odontogenic tumor: report of 5 new cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94:614–21.CrossRef
5.
Ardekian L, Manor R, Gaspar R, Laufer D. Central granular cell odontogenic tumor: case report and review of literature. J Oral Maxillofac Surg. 1998;56:1343–5.CrossRef
6.
Piattelli A, Rubini C, Goteri G, Fioroni M, Maiorano E. Central granular cell odontogenic tumour: report of the first malignant case and review of the literature. Oral Oncol. 2003;39:78–82.CrossRef
7.
Mirchandani R, Sciubba JJ, Mir R. Granular cell lesions of the jaws and oral cavity: a clinicopathologic, immunohistochemical, and ultrastructural study. J Oral Maxillofac Surg. 1989;47:1248–55.CrossRef
8.
Chiang CT, Hu KY, Tsai CC. Central granular cell odontogenic tumor: the first reported case in Oriental people and literature review. J Formos Med Assoc. 2014;113:321–5.CrossRef
9.
Atarbashi-Moghadam S, Saebnoori H, Shamloo N, Dehghanpour Barouj M, Saedi S. Granular cell odontogenic tumor, an extremely rare case report. J Dent (Shiraz). 2019;20:220–3.
10.
Madan M, Chandra S, Raj V, Madan R. Central granular cell odontogenic tumor: report of an unusual case. Indian J Dent Res. 2016;27:220–2.CrossRef
11.
Vennamaneni N. Granular cell odontogenic tumour—a histopathological rarity. Org Med Chem Int J. 2016;1:555558.
12.
Fletcher SM, Chengot P, Dalghous A, Mizen K. A granular-cell odontogenic tumour occurring alongside orofacial granulomatosis: a report of the first case. Oral Surg. 2015;8:42–7.CrossRef
13.
Lee JJ, Wei LY, Wu YC, Chiang CP. An early central granular cell odontogenic tumor arising from the dental follicle of an impacted mandibular third molar. J Formos Med Assoc. 2014;113:766–8.CrossRef
14.
Cheng SJ, Wang YP, Chen HM, Chiang CP. Central granular cell odontogenic tumor ofthe mandible. J Formos Med Assoc. 2013;112:583–5.CrossRef
15.
Anbiaee N, Saghafi S, Mohammadzadeh Rezaei M. Central granular cell odontogenic tumor: report of a case with CBCT features. J Dent (Tehran). 2014;11:365–70.
16.
Couch RD, Morris EE, Vellios F. Granular cell ameloblastic fibroma: report of 2 cases in adults, with observations on its similarity to congenital epulis. Am J Clin Pathol. 1962;37:398–404.CrossRef
17.
Vincent SD, Hammond HL, Ellis GL, Juhlin JP. Central granular cell odontogenic fibroma. Oral Surg Oral Med Oral Pathol. 1987;63:715–21.CrossRef
18.
Neville B, Damm D, Allen C, Chi A. Oral and maxillofacial pathology. 4th ed. Amsterdam: Elsevier; 2015. p. 632–89.
19.
Cadavid AMH, Teshima THN, Pinto CAL, Camillo CMC, Lourenço SV. Ameloblastoma with distinctive granular cell pattern: an 8 case study. Autops Case Rep. 2018;8(4):e2018052.CrossRef
Metadata
Title
Granular cell odontogenic tumor: report of a rare case and a review of literature
Authors
Milad Etemadi Sh
Sayed Mohammad Razavi
Olia Ghazavi
Mohammad Hossein Nikbakht
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2022
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-022-02097-2

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