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Published in: BMC Oral Health 1/2018

Open Access 01-12-2018 | Research article

Oral hygiene and periodontal conditions in the Chinese patients with aortic aneurysm

Authors: Fang Ding, Di Wu, Xiao Han, Li-Jian Cheng, Zheng Sun, Ya-Lin Lv

Published in: BMC Oral Health | Issue 1/2018

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Abstract

Background

This cross-sectional study aims to evaluate the association of periodontal conditions and oral hygiene habits in the Chinese patients with an aortic aneurysm (AA).

Methods

A questionnaire and periodontal examinations were carried out in the AA patients and non-AA volunteers recruited from the Center for Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University between August 2011 and June 2016. General information (e.g., height and weight), history of systemic diseases, and oral hygiene habits (e.g., brushing methods and regular oral examinations) were collected in the self-reported survey. Periodontal examinations, such as plaque index and bleeding index, were conducted in all the subjects. The correlation between periodontal indices and AA was further explored using univariate and multivariate analyses.

Results

Our analyses revealed that 87.6% of AA patients have chronic periodontitis, which is significantly higher than that of the non-AA patients (55.8%). In addition, AA patients demonstrated more severe periodontal damages with 69.3% moderate and severe periodontitis, compared to only 16.0% in the non-AA group. Using AA as the dependent variable and all the potential risk factors as covariates (e.g., gender, age, smoking, obesity, diabetes, hypertension, and hyperlipidemia), a logistic regression analysis was performed to show clinical attachment loss (CAL) being an independent risk factor for AA (OR = 2.309, 95% CI: 1.623–3.284, p = 0.000). In comparison with the non-AA patients, more AA patients have poor oral hygiene habits and don’t have regular dental appointments for supra-gingival cleaning.

Conclusion

Poor periodontal condition and dental hygiene were identified in the AA patients, suggesting that periodontitis-induced CAL may play a role in AA disease mechanisms.
Literature
1.
go back to reference Gillum RF. Epidemiology of aortic aneurysm in the United States. J Clin Epidemiol. 1995;48(11):1289–98.CrossRefPubMed Gillum RF. Epidemiology of aortic aneurysm in the United States. J Clin Epidemiol. 1995;48(11):1289–98.CrossRefPubMed
2.
3.
go back to reference Dua A, Kuy S, Lee CJ, Upchurch GR Jr, Desai SS. Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010. J Vasc Surg. 2014;59(6):1512–7.CrossRefPubMed Dua A, Kuy S, Lee CJ, Upchurch GR Jr, Desai SS. Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010. J Vasc Surg. 2014;59(6):1512–7.CrossRefPubMed
5.
go back to reference Vardulaki KA, Walker NM, Day NE, Duffy SW, Ashton HA, Scott RA. Quantifying the risks of hypertension, age, sex and smoking in patients with abdominal aortic aneurysm. Br J Surg. 2000;87(2):195–200.CrossRefPubMed Vardulaki KA, Walker NM, Day NE, Duffy SW, Ashton HA, Scott RA. Quantifying the risks of hypertension, age, sex and smoking in patients with abdominal aortic aneurysm. Br J Surg. 2000;87(2):195–200.CrossRefPubMed
6.
go back to reference Lindholt JS, Heegaard NH, Vammen S, Fasting H, Henneberg EW, Heickendorff L. Smoking, but not lipids, lipoprotein(a) and antibodies against oxidised LDL, is correlated to the expansion of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2001;21(1):51–6.CrossRefPubMed Lindholt JS, Heegaard NH, Vammen S, Fasting H, Henneberg EW, Heickendorff L. Smoking, but not lipids, lipoprotein(a) and antibodies against oxidised LDL, is correlated to the expansion of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2001;21(1):51–6.CrossRefPubMed
7.
go back to reference Bartova J, Sommerova P, Lyuya-Mi Y, Mysak J, Prochazkova J, Duskova J, Janatova T, Podzimek S. Periodontitis as a risk factor of atherosclerosis. J Immunol Res. 2014;2014:636893.CrossRefPubMedPubMedCentral Bartova J, Sommerova P, Lyuya-Mi Y, Mysak J, Prochazkova J, Duskova J, Janatova T, Podzimek S. Periodontitis as a risk factor of atherosclerosis. J Immunol Res. 2014;2014:636893.CrossRefPubMedPubMedCentral
8.
go back to reference Figuero E, Lindahl C, Marin MJ, Renvert S, Herrera D, Ohlsson O, Wetterling T, Sanz M. Quantification of periodontal pathogens in vascular, blood, and subgingival samples from patients with peripheral arterial disease or abdominal aortic aneurysms. J Periodontol. 2014;85(9):1182–93.CrossRefPubMed Figuero E, Lindahl C, Marin MJ, Renvert S, Herrera D, Ohlsson O, Wetterling T, Sanz M. Quantification of periodontal pathogens in vascular, blood, and subgingival samples from patients with peripheral arterial disease or abdominal aortic aneurysms. J Periodontol. 2014;85(9):1182–93.CrossRefPubMed
9.
go back to reference Cheng SW, Ting AC, Tsang SH. Epidemiology and outcome of aortic aneurysms in Hong Kong. World J Surg. 2003;27(2):241–5.PubMed Cheng SW, Ting AC, Tsang SH. Epidemiology and outcome of aortic aneurysms in Hong Kong. World J Surg. 2003;27(2):241–5.PubMed
10.
go back to reference 1999 International International Workshop for a Classification of Periodontal Diseases and Conditions. Papers. Oak Brook, Illinois, October 30–November 2, 1999. Ann Periodontol. 1999;4(1):i, 1–112. 1999 International International Workshop for a Classification of Periodontal Diseases and Conditions. Papers. Oak Brook, Illinois, October 30–November 2, 1999. Ann Periodontol. 1999;4(1):i, 1–112.
11.
go back to reference Armitage GC. Development of a classification system for periodontal diseases and conditions. Annals of periodontology. 1999;4(1):1–6.CrossRefPubMed Armitage GC. Development of a classification system for periodontal diseases and conditions. Annals of periodontology. 1999;4(1):1–6.CrossRefPubMed
12.
go back to reference Salo JA, Perhoniemi VJ, Lepantalo MJ, Mattila PS. Prognosis of patients over 75 years of age with a ruptured abdominal aortic aneurysm. World J Surg. 1989;13(4):484–6. discussion 486-487CrossRefPubMed Salo JA, Perhoniemi VJ, Lepantalo MJ, Mattila PS. Prognosis of patients over 75 years of age with a ruptured abdominal aortic aneurysm. World J Surg. 1989;13(4):484–6. discussion 486-487CrossRefPubMed
13.
go back to reference Loesche WJ, Schork A, Terpenning MS, Chen YM, Dominguez BL, Grossman N. Assessing the relationship between dental disease and coronary heart disease in elderly U.S. veterans. J Am Dent Assoc. 1998;129(3):301–11.CrossRefPubMed Loesche WJ, Schork A, Terpenning MS, Chen YM, Dominguez BL, Grossman N. Assessing the relationship between dental disease and coronary heart disease in elderly U.S. veterans. J Am Dent Assoc. 1998;129(3):301–11.CrossRefPubMed
14.
go back to reference Soto-Barreras U, Olvera-Rubio JO, Loyola-Rodriguez JP, Reyes-Macias JF, Martinez-Martinez RE, Patino-Marin N, Martinez-Castanon GA, Aradillas-Garcia C, Little JW. Peripheral arterial disease associated with caries and periodontal disease. J Periodontol. 2013;84(4):486–94.CrossRefPubMed Soto-Barreras U, Olvera-Rubio JO, Loyola-Rodriguez JP, Reyes-Macias JF, Martinez-Martinez RE, Patino-Marin N, Martinez-Castanon GA, Aradillas-Garcia C, Little JW. Peripheral arterial disease associated with caries and periodontal disease. J Periodontol. 2013;84(4):486–94.CrossRefPubMed
15.
go back to reference Mattila KJ, Valle MS, Nieminen MS, Valtonen VV, Hietaniemi KL. Dental infections and coronary atherosclerosis. Atherosclerosis. 1993;103(2):205–11.CrossRefPubMed Mattila KJ, Valle MS, Nieminen MS, Valtonen VV, Hietaniemi KL. Dental infections and coronary atherosclerosis. Atherosclerosis. 1993;103(2):205–11.CrossRefPubMed
16.
go back to reference Mattila KJ. Dental infections as a risk factor for acute myocardial infarction. Eur Heart J. 1993;14(Suppl K):51–3.PubMed Mattila KJ. Dental infections as a risk factor for acute myocardial infarction. Eur Heart J. 1993;14(Suppl K):51–3.PubMed
17.
go back to reference Mendez MV, Scott T, LaMorte W, Vokonas P, Menzoian JO, Garcia R. An association between periodontal disease and peripheral vascular disease. Am J Surg. 1998;176(2):153–7.CrossRefPubMed Mendez MV, Scott T, LaMorte W, Vokonas P, Menzoian JO, Garcia R. An association between periodontal disease and peripheral vascular disease. Am J Surg. 1998;176(2):153–7.CrossRefPubMed
18.
go back to reference Ismail A, Khosravi H, Olson H. The role of infection in atherosclerosis and coronary artery disease: a new therapeutic target. Heart Dis. 1999;1(4):233–40.PubMed Ismail A, Khosravi H, Olson H. The role of infection in atherosclerosis and coronary artery disease: a new therapeutic target. Heart Dis. 1999;1(4):233–40.PubMed
19.
go back to reference Marques da Silva R, Lingaas PS, Geiran O, Tronstad L, Olsen I. Multiple bacteria in aortic aneurysms. J Vasc Surg. 2003;38(6):1384–9.CrossRefPubMed Marques da Silva R, Lingaas PS, Geiran O, Tronstad L, Olsen I. Multiple bacteria in aortic aneurysms. J Vasc Surg. 2003;38(6):1384–9.CrossRefPubMed
20.
go back to reference Marques da Silva R, Caugant DA, Lingaas PS, Geiran O, Tronstad L, Olsen I. Detection of Actinobacillus actinomycetemcomitans but not bacteria of the red complex in aortic aneurysms by multiplex polymerase chain reaction. J Periodontol. 2005;76(4):590–4.CrossRefPubMed Marques da Silva R, Caugant DA, Lingaas PS, Geiran O, Tronstad L, Olsen I. Detection of Actinobacillus actinomycetemcomitans but not bacteria of the red complex in aortic aneurysms by multiplex polymerase chain reaction. J Periodontol. 2005;76(4):590–4.CrossRefPubMed
21.
go back to reference Kurihara N, Inoue Y, Iwai T, Umeda M, Huang Y, Ishikawa I. Detection and localization of periodontopathic bacteria in abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2004;28(5):553–8.CrossRefPubMed Kurihara N, Inoue Y, Iwai T, Umeda M, Huang Y, Ishikawa I. Detection and localization of periodontopathic bacteria in abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2004;28(5):553–8.CrossRefPubMed
22.
go back to reference Rafferty B, Jonsson D, Kalachikov S, Demmer RT, Nowygrod R, Elkind MS, Bush H Jr, Kozarov E. Impact of monocytic cells on recovery of uncultivable bacteria from atherosclerotic lesions. J Intern Med. 2011;270(3):273–80.CrossRefPubMedPubMedCentral Rafferty B, Jonsson D, Kalachikov S, Demmer RT, Nowygrod R, Elkind MS, Bush H Jr, Kozarov E. Impact of monocytic cells on recovery of uncultivable bacteria from atherosclerotic lesions. J Intern Med. 2011;270(3):273–80.CrossRefPubMedPubMedCentral
23.
go back to reference Paraskevas KI, Mikhailidis DP, Giannoukas AD. Periodontitis and abdominal aortic aneurysms: a random association or a pathogenetic link? Int Angiol. 2009;28(6):431–3.PubMed Paraskevas KI, Mikhailidis DP, Giannoukas AD. Periodontitis and abdominal aortic aneurysms: a random association or a pathogenetic link? Int Angiol. 2009;28(6):431–3.PubMed
24.
go back to reference Parahitiyawa NB, Jin LJ, Leung WK, Yam WC, Samaranayake LP. Microbiology of odontogenic bacteremia: beyond endocarditis. Clin Microbiol Rev. 2009;22(1):46–64. Table of ContentsCrossRefPubMedPubMedCentral Parahitiyawa NB, Jin LJ, Leung WK, Yam WC, Samaranayake LP. Microbiology of odontogenic bacteremia: beyond endocarditis. Clin Microbiol Rev. 2009;22(1):46–64. Table of ContentsCrossRefPubMedPubMedCentral
25.
go back to reference Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M. High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm. Int Heart J. 2014;55(3):268–70.CrossRefPubMed Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M. High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm. Int Heart J. 2014;55(3):268–70.CrossRefPubMed
26.
go back to reference Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M. Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia. Heart Vessel. 2015;30(4):498–502.CrossRef Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, Shigematsu K, Hoshina K, Izumi Y, Komuro I, Miyata T, Hirata Y, Isobe M. Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia. Heart Vessel. 2015;30(4):498–502.CrossRef
27.
go back to reference Scannapieco FA, Cantos A. Oral inflammation and infection, and chronic medical diseases: implications for the elderly. Periodontol 2000. 2016;72(1):153–75.CrossRefPubMed Scannapieco FA, Cantos A. Oral inflammation and infection, and chronic medical diseases: implications for the elderly. Periodontol 2000. 2016;72(1):153–75.CrossRefPubMed
28.
go back to reference Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000. 2013;62(1):59–94.CrossRefPubMed Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000. 2013;62(1):59–94.CrossRefPubMed
29.
go back to reference Redfern J. Smart health and innovation: facilitating health-related behaviour change. Proc Nutr Soc. 2017;76(3):328–32.CrossRefPubMed Redfern J. Smart health and innovation: facilitating health-related behaviour change. Proc Nutr Soc. 2017;76(3):328–32.CrossRefPubMed
Metadata
Title
Oral hygiene and periodontal conditions in the Chinese patients with aortic aneurysm
Authors
Fang Ding
Di Wu
Xiao Han
Li-Jian Cheng
Zheng Sun
Ya-Lin Lv
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2018
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-018-0594-3

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