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BMC Oral Health
Published in: BMC Oral Health 1/2015

Open Access 01-12-2015 | Research article

Erosive esophageal reflux vs. non erosive esophageal reflux: oral findings in 71 patients

Authors: Herbert Deppe, Thomas Mücke, Stefan Wagenpfeil, Marco Kesting, Anna Rozej, Monther Bajbouj, Anton Sculean

Published in: BMC Oral Health | Issue 1/2015

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Abstract

Background

The purpose of this clinical study was to assess the prevalence of acidic oral mucosal lesions and periodontal conditions in patients suffering from erosive esophageal reflux disease (ERD) compared with non erosive esophageal reflux disease (NERD) patients, both treated with long term proton pump inhibitors (PPI).

Methods

Seventy-one patients with diagnosed GERD were studied: i.e. 29 ERD and 42 NERD patients. Thorough visual examination of the oral mucosa and a periodontal evaluation was performed. The primary outcome was defined as a statistically significant difference, between the two groups, in the presence of acidic lesions of the oral mucosa and specific periodontal parameters.

Results

This study failed to demonstrate statistically significant differences between ERD and NERD patients with respect to the prevalence of oral mucosal lesions. However, significantly more ERD patients suffered from severe periodontitis (CAL ≥ 5 mm) as compared to NERD patients. Accordingly, it may be assumed that PPI-use had no adverse effects on the prevalence of acidic oral mucosal lesions and on periodontal destruction.

Conclusions

Within the limitations of this study it may be concluded that ERD and NERD patients need separate evaluation with respect to periodontal destruction. Moreover, long term PPI medication had no adverse clinical impact on acidic oral mucosal lesions and periodontal destruction. Further studies are necessary to elucidate the role of reflux in the periodontal destruction of ERD individuals.
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Metadata
Title
Erosive esophageal reflux vs. non erosive esophageal reflux: oral findings in 71 patients
Authors
Herbert Deppe
Thomas Mücke
Stefan Wagenpfeil
Marco Kesting
Anna Rozej
Monther Bajbouj
Anton Sculean
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2015
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-015-0069-8

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