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BMC Oral Health
Published in: BMC Oral Health 1/2015

Open Access 01-12-2015 | Research article

Use of alcohol vinegar in the inhibition of Candida spp. and its effect on the physical properties of acrylic resins

Authors: Ricardo Dias de Castro, Ana Carolina Loureiro Gama Mota, Edeltrudes de Oliveira Lima, André Ulisses Dantas Batista, Julyana de Araújo Oliveira, Alessandro Leite Cavalcanti

Published in: BMC Oral Health | Issue 1/2015

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Abstract

Background

Given the high prevalence of oral candidiasis and the restricted number of antifungal agents available to control infection, this study investigated the in vitro antifungal activity of alcohol vinegar on Candida spp. and its effect on the physical properties of acrylic resins.

Methods

Tests to determine the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of vinegar alcohol (0.04 g/ml of acetic acid) and nystatin (control) were performed. The antifungal activity of alcohol vinegar was assessed through microbial growth kinetic assays and inhibition of Candida albicans adhesion to acrylic resin at different intervals of time. Surface roughness and color of the acrylic resin were analyzed using a roughness meter and color analyzer device.

Results

Alcohol vinegar showed MIC75% and MFC62.5% of 2.5 mg/ml, with fungicidal effect from 120 min, differing from nystatin (p < 0.0001), which showed fungistatic effect. Alcohol vinegar caused greater inhibition of C. albicans adhesion to the acrylic resin (p ≤ 0.001) compared to nystatin and did not change the roughness and color parameters of the material.

Conclusion

Alcohol vinegar showed antifungal properties against Candida strains and caused no physical changes to the acrylic resin.
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Metadata
Title
Use of alcohol vinegar in the inhibition of Candida spp. and its effect on the physical properties of acrylic resins
Authors
Ricardo Dias de Castro
Ana Carolina Loureiro Gama Mota
Edeltrudes de Oliveira Lima
André Ulisses Dantas Batista
Julyana de Araújo Oliveira
Alessandro Leite Cavalcanti
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2015
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-015-0035-5

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