Mayo Adhesive Probability (MAP) score of non-donated kidney aids in predicting post-operative renal function following donor nephrectomy

To examine the association of preoperative Mayo Adhesive Probability (MAP) scores in the donor (MAP_d) and non-donor kidneys (MAP_nd) with post-donation renal function.

Three hundred thirty-one patients undergoing hand assisted laparoscopic donor nephrectomy (HALDN) were reviewed. MAP_d and MAP_nd were obtained. Estimated glomerular filtration rate (eGFR) was recorded preoperatively and at 1 day, 1 month, and 6 months postoperatively.

Two hundred females and 131 males were evaluated with median BMI 26.4 kg/m² (range 17.1–39.6) and median age 45 years (range 19–78). MAP_d score was 0 for 231 patients (69.8%) and > 0 for 100 patients (30.2%). MAP_nd score was 0 for 234 patients (70.7%) and > 0 for 97 patients (29.3%). The median preoperative eGFR was 86.6 ml/min/1.73m² (range 48.8–138.4). After adjusting for preoperative eGFR, BMI, ASA score, and kidney sidedness, postoperative eGFR was associated with MAP score in the non-donated kidney (p = 0.014) but not in the donated kidney (p = 0.24). Compared to donors with MAP_nd = 0, donors with a MAP_nd > 0, mean eGFR was − 2.33 ml/min/1.73m² lower at postoperative day 1 (95% CI − 4.24 to − 0.41, p = 0.018), − 3.02 ml/min/1.73m² lower at 1 month (95% CI − 5.11 to − 0.93, p = 0.005), and − 2.63 ml/min/1.73m² lower at 6 months postoperatively (95% CI − 5.01 to − 0.26, p = 0.030).

MAP score > 0 in the non-donated kidney is associated with worse renal function in the 6 months following HALDN.