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BMC Urology
Published in: BMC Urology 1/2020

01-12-2020 | Multiple Sclerosis | Research article

Quality of life among patients with multiple sclerosis and voiding dysfunction: a cross-sectional study

Authors: Fatemeh Nazari, Vahid Shaygannejad, Mehrdad Mohammadi Sichani, Marjan Mansourian, Valiollah Hajhashemi

Published in: BMC Urology | Issue 1/2020

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Abstract

Background

Evaluating the usefulness of treatment requires a direct measurement of the health-related quality of life (QOL). Therefore, this study was carried out aiming to determine the QOL of patients with MS and voiding dysfunction.

Methods

This cross-sectional study was carried out using multi-stage random cluster sampling method on 602 patients with MS in Isfahan, Iran. All data were collected through interviews using standard questionnaires including International Prostate Symptom Score (IPSS), and the Multiple Sclerosis Quality of Life-54 (MSQOL-54). Data were analyzed using descriptive and inferential statistical tests.

Results

The prevalence rate of mixed, irritative, and obstructive urinary symptoms was 52.2, 25.5, and 6.5%, respectively. The mixed symptom had the highest prevalence among men and women with rates of 56.5 and 51.1%, respectively. The prevalence of irritative and obstructive symptoms was, respectively, higher and statistically significant among women alone and men alone (P <  0.05). The prevalence of irritative symptoms was higher among patients with MS, EDSS score ≤ 3, disease duration of less than 5 years, and with clinically isolated syndrome. In addition, the prevalence of mixed symptoms was higher among patients with MS of over 30 years of age with a Pre-high school degree, severe disability, disease duration of over 10 years, and progressive MS; the difference was statistically significant (P <  0.05). There was a difference in the combined dimensions of physical and mental health of QOL between the two groups with and without urinary symptoms (P <  0.05). Logistic regression analysis revealed that there was a higher probability of a urinary problems among patients with MS and high age [3.273 (1.083–9.860); P = 0.035].

Conclusions

Mixed urinary symptoms are highly prevalent among MS patients and affect QOL dimensions. In order to improve QOL, more attention and focus should be paid to urinary problems in MS patients.
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Metadata
Title
Quality of life among patients with multiple sclerosis and voiding dysfunction: a cross-sectional study
Authors
Fatemeh Nazari
Vahid Shaygannejad
Mehrdad Mohammadi Sichani
Marjan Mansourian
Valiollah Hajhashemi
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2020
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-020-00590-w

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