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Published in: BMC Urology 1/2018

Open Access 01-12-2018 | Case report

Fungaemia caused by obstructive renal candida bezoars leads to bilateral chorioretinitis: a case report

Authors: Johannes Stein, Stefan Latz, Jörg Ellinger, Guido Fechner, Maher Safi, Philipp Krausewitz, Simone Müller, Karin Weyer, Stefan C. Müller

Published in: BMC Urology | Issue 1/2018

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Abstract

Background

Renal fungal bezoars are remarkably rare and mostly occur in immunodeficient patients. Only a small number of cases with immunocompetent patients have been published so far. The published treatment approaches comprised systemic antimycotic therapy and surgical or minimal invasive removal of the fungal balls. In some cases irrigation of the renal duct system with amphotericin B was performed.
By obstruction of the urinary tract bezoars can lead to infected hydronephrosis and severe urosepsis with high lethality. Fungaemia can cause fungal colonization in different distant organs. Fulminant chorioretinitis and irreversible visual impairment can be the consequence of ocular fundus colonization. The following report highlights that a co-operation between urologists and ophthalmologists is absolutely indispensible in case of fungaemia.

Case presentation

Hereinafter we describe a case of an immunocompetent 56 years old woman, presenting with flank pain and shivering. The diagnosis turned out to be difficult due to initially negative urine culture. The fungaemia caused by obstructive nephropathy led to bilateral candida chorioretinitis. The patient was treated with intravenous amphotericin b and the bezoar was removed by percutaneous “nephrolitholapaxy”.
After two months, a follow up revealed the patient felt well, chorioretinal lesions regressed and urine culture did not show any fungal growth.

Conclusion

To the best of our knowledge, this is the first case reporting on obstructive renal bezoars, which lead to haematogenous fungus spread and bilateral chorioretinitis.
It points out that extensive ophthalmologic examination should be performed in case of fungaemia even if the patient is not suffering from any visual impairment.
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Metadata
Title
Fungaemia caused by obstructive renal candida bezoars leads to bilateral chorioretinitis: a case report
Authors
Johannes Stein
Stefan Latz
Jörg Ellinger
Guido Fechner
Maher Safi
Philipp Krausewitz
Simone Müller
Karin Weyer
Stefan C. Müller
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2018
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-018-0335-6

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