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Open Access 01-12-2019 | Thyroidectomy | Research article

Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy

Authors: Daqi Zhang, Tie Wang, Gianlorenzo Dionigi, Jiao Zhang, Yishen Zhao, Gaofeng Xue, Nan Liang, Hui Sun

Published in: BMC Surgery | Issue 1/2019

Abstract

Background

In this study, we aimed to compare the kinetics of intact parathyroid hormone (iPTH) during the perioperative period of endoscopic thyroidectomy via bilateral areola approach (ETBAA) in the same period, following a traditional open thyroidectomy approach (OTA).

Methods

We conducted a prospective observational study of patients who were undergoing thyroidectomy and level VI clearance. Patients who had been affected by papillary thyroid cancer (PTC) were stratified into three groups: those eligible for endoscopic treatment (ETBAA); patients who were eligible for ETBAA but had opted for OTA (OTA-L); and patients who were not suitable for endoscopic intervention (OTA-H). A process for locating parathyroid glands was utilized to stratify gland dissection laboriousness. In Type A, the gland is firmly fixed to thyroid gland. This type can be sub-classified into three subtypes. A1: the parathyroid gland is attached to the inherent thyroid capsule. A2: the gland is partially embedded in the thyroid gland. A3: the gland is located in the thyroid tissue. Type B is defined as a gland which is separated from the thyroid gland. The iPTH was sampled at wound closure.

Results

There were 100 patients in each group. We found a significant difference between the ETBAA and OTA-H groups for type A2, as well as a loss of parathyroid glands and a number of parathyroid transplantation procedures. The endoscopic group was treated during an earlier stage of thyroid cancer. The iPTH profile of each group decreased, although this was the most consistent in the OTA-H group. A comparison of ETBAA with OTA-L demonstrates that the iPTH level change is similar.

Conclusion

There is no advantage of endoscopic treatment for preserving parathyroid function.

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Title: Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy
Authors: Daqi Zhang
Tie Wang
Gianlorenzo Dionigi
Jiao Zhang
Yishen Zhao
Gaofeng Xue
Nan Liang
Hui Sun
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Thyroidectomy
Thyroidectomy
Hypocalcemia
Thyroid Cancer
Thyroid Cancer
Thyroid Cancer
Published in: BMC Surgery / Issue 1/2019
Electronic ISSN: 1471-2482
DOI: https://doi.org/10.1186/s12893-019-0656-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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