Open Access 01-12-2016 | Case report
Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
Published in: BMC Surgery | Issue 1/2016
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Background
Malignant thymomas are rarely associated with bone metastasis and T-cell lymphocytosis.
Case presentation
A 47–year-old female patient was admitted to our hospital for ptosis. A diagnosis of malignant thymoma was made based on the thymectomy and pathological result. Peripheral T-cell lymphocytosis and bone metastasis were found later. T-cell lymphocytosis was relived after surgical and radiation therapy to the metastasis.
Conclusion
Peripheral T-cell lymphocytosis is a rare paraneoplastic phenomenon associated with thymomas. This report is the first to describe an invasive thymoma with late bone metastasis accompanied with T-cell lymphocytosis. We should be aware of peripheral T-cell lymphocytosis in thymomas and it may contribute to a better understanding of the complex physiology and pathogenesis of thymoma.