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BMC Surgery
Published in: BMC Surgery 1/2015

Open Access 01-12-2015 | Case report

Kikuchi-Fujimoto lymphadenitis imitating metastatic melanoma on positron emission tomography: a case report

Authors: Peter Urbanellis, Laura Chin-Lenn, Carolin J Teman, J Gregory McKinnon

Published in: BMC Surgery | Issue 1/2015

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Abstract

Background

Accurate staging is critical for decision-making for the treatment of malignant conditions. Fluoro-deoxy-glucose positron emission tomography-computed tomography (FDG PET-CT) is a highly sensitive imaging modality for the assessment of distant metastases; however false positive results are possible due to its lower specificity with detection of other hypermetabolic pathologies.

Case presentation

A patient with high-risk thigh melanoma was staged with FDG PET-CT. Four ipsilateral inguinal nodes (three superficial, one deep) demonstrated intense hypermetabolic activity. Metastatic melanoma was confirmed in the largest superficial inguinal node with ultrasound-guided fine needle aspiration. Histopathology demonstrated metastatic melanoma in one superficial node and histiocytic necrotizing lymphadenitis, also known as Kikuchi-Fujimoto disease in five deep inguinal nodes.

Conclusion

This case illustrates a false positive FDG PET-CT due to coincidental, synchronous melanoma and Kikuchi-Fujimoto disease in the same draining lymph node basin.
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Metadata
Title
Kikuchi-Fujimoto lymphadenitis imitating metastatic melanoma on positron emission tomography: a case report
Authors
Peter Urbanellis
Laura Chin-Lenn
Carolin J Teman
J Gregory McKinnon
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2015
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-015-0036-y

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