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BMC Musculoskeletal Disorders

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Open Access 01-12-2021 | Rheumatoid Arthritis | Research article

Effective factors on Sharp Score in patients with rheumatoid arthritis: a retrospective study

Authors: Jianting Wen, Jian Liu, Ling Xin, Lei Wan, Hui Jiang, Yue Sun, Yanqiu Sun, Xin Wang, Jie Wang

Published in: BMC Musculoskeletal Disorders | Issue 1/2021

Abstract

Background

This study aims to describe the association between sharp score and clinical indexes, bone metabolism indexes, Disease Activity Score (DAS28) and sociodemographic factors in rheumatoid arthritis (RA).

Methods

Data were collected from the HIS (hospital information system), a national inpatient database in China, with information on the patients hospitalized during the period from 2012 to 2019. The association between sharp score and effective factors were identified using multinomial logistic regression and association rule mining (ARM).

Results

Three thousand eight hundred and forty patients were included: 82.66% males, 17.34% females, mean (SD) age 56.95 (12.68) years and symptom duration 3.45 (1.09) years. Spearman correlation analysis and Association rules analysis showed that there were significant positive correlations between sharp score and effective factors. Logistic regression analysis presented that erythrocyte sedimentation rate (ESR), high-sensitivity C-reactive protein (CRP), rheumatoid factor (RF) were risk factors of sharp score. In the analysis of individual outcomes, sex, age, symptom duration, DSA28 score, RF, ever drinker, and radiographic grading of hands were influence factors of sharp score.

Conclusion

Sharp score should be taken into consideration in formulating treatment strategies in RA.

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Title: Effective factors on Sharp Score in patients with rheumatoid arthritis: a retrospective study
Authors: Jianting Wen
Jian Liu
Ling Xin
Lei Wan
Hui Jiang
Yue Sun
Yanqiu Sun
Xin Wang
Jie Wang
Publication date: 01-12-2021
Publisher: BioMed Central
Keyword: Rheumatoid Arthritis
Published in: BMC Musculoskeletal Disorders / Issue 1/2021
Electronic ISSN: 1471-2474
DOI: https://doi.org/10.1186/s12891-021-04742-3

At a glance: The STEP trials

Springer Medicine

Effective factors on Sharp Score in patients with rheumatoid arthritis: a retrospective study

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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