Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2019

Open Access 01-12-2019 | Magnetic Resonance Imaging | Research article

Imaging for Dupuytren disease: a systematic review of the literature

Authors: Sanne Molenkamp, Roel J. M. van Straalen, Paul M. N. Werker, Dieuwke C. Broekstra

Published in: BMC Musculoskeletal Disorders | Issue 1/2019

Login to get access

Abstract

Background

As treatment of Dupuytren disease (DD) is expected to shift towards prevention of progression, the use of imaging in patients with DD becomes more important. In this systematic review an overview is given of the different methods for and applications of imaging for DD that have been described.

Methods

The MEDLINE and EMBASE databases were searched for articles reporting the use of imaging in patients with DD, published before May 17, 2018. Studies were systematically examined in two rounds by two observers according to the PRISMA systematic. All studies containing original data on imaging for DD were considered for inclusion.

Results

Three hundred and seven unique studies were identified, of which 23 were included in the study. Only studies on the use of ultrasound (US) and magnetic resonance imaging (MRI) were identified. Broadly, articles could be divided into 5 categories. Seven studies were found on diagnosis, two on measurement of disease extent, four on measurement of disease activity, seven on guidance of minimally invasive procedures and five studies on evaluation of treatment. According to the Oxford CEBM, the levels of evidence were low, ranging from level 3 to 5.

Conclusions

A variety of applications for US and MRI for patients with DD has been described. Based on the results of this review, the largest value for imaging lies in the measurement of disease activity and the follow-up of treatment of patients with early stage disease. Unfortunately, the overall level of evidence of the available literature was low. Future research is necessary to define the exact value of US and MRI in the management of patients with DD.
Literature
1.
Becker K, Siegert S, Toliat MR, Du J, Casper R, Dolmans GH, et al. Meta-analysis of genome-wide association studies and network analysis-based integration with gene expression data identify new suggestive loci and unravel a Wnt-centric network associated with Dupuytren's disease. PLoS One. 2016;11(7):e0158101.PubMedPubMedCentralCrossRef
2.
Broekstra DC, Groen H, Molenkamp S, Werker PMN, van den Heuvel ER. A systematic review and meta-analysis on the strength and consistency of the associations between Dupuytren disease and diabetes mellitus, liver disease, and epilepsy. Plast Reconstr Surg. 2018;141(3):379e.CrossRef
3.
Descatha A, Jauffret P, Chastang JF, Roquelaure Y, Leclerc A. Should we consider Dupuytren's contracture as work-related? A review and meta-analysis of an old debate. BMC Musculoskelet Disord. 2011;12:96.PubMedPubMedCentralCrossRef
4.
Lanting R, Broekstra DC, Werker PM, van den Heuvel ER. A systematic review and meta-analysis on the prevalence of Dupuytren disease in the general population of Western countries. Plast Reconstr Surg. 2014;133(3):593–603.PubMedCrossRef
5.
Gudmundsson KG, Arngrimsson R, Sigfusson N, Bjornsson A, Jonsson T. Epidemiology of Dupuytren’s disease: clinical, serological, and social assessment The Reykjavik Study. J Clin Epidemiol. 2000;53(3):291–6.PubMedCrossRef
6.
Gudmundsson KG, Arngrimsson R, Jonsson T. Eighteen years follow-up study of the clinical manifestations and progression of Dupuytren's disease. Scand J Rheumatol. 2001;30(1):31–4.PubMedCrossRef
7.
Lanting R, van den Heuvel ER, Werker PM. Clusters in short-term disease course in participants with primary Dupuytren disease. J Hand Surg Am. 2016;41(3):61 quiz 361.CrossRef
8.
Degreef I, De Smet L. Dupuytren disease: on our way to a cure? Acta Orthop Belg. 2013;79(3):243–9.PubMed
9.
Dolmans GH, de Bock GH, Werker PM. Dupuytren diathesis and genetic risk. J Hand Surg Am. 2012;37(10):2106–11.PubMedCrossRef
10.
Broekstra DC, Lanting R, Werker PM, van den Heuvel ER. Intra- and inter-observer agreement on diagnosis of Dupuytren disease, measurements of severity of contracture, and disease extent. Man Ther. 2015;20(4):580–6.PubMedCrossRef
11.
Creteur V, Madani A, Gosset N. Ultrasound imaging of Dupuytren's contracture. J Radiol. 2010;91(6):687–91.PubMedCrossRef
12.
Walker EA, Petscavage JM, Brian PL, Logie CI, Montini KM, Murphey MD. Imaging features of superficial and deep fibromatoses in the adult population. Sarcoma. 2012;2012:215810.PubMedPubMedCentralCrossRef
13.
Guerini H, Morvan G, Vuillemin V, Campagna R, Thevenin F, Larousserie F, et al. Ultrasound of wrist and hand masses. Diagn Interv Imaging. 2015;96(12):1247–60.PubMedCrossRef
14.
Mauch F, Drews B. Magnetic resonance imaging and computed tomography : what is important in orthopedics and traumatology. Unfallchirurg. 2016;119(10):790–802.PubMedCrossRef
15.
16.
17.
Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 2010;8(5):336–41.PubMedCrossRef
18.
19.
Juvenspan M, Schlur C, Thomsen L, Colom A, Audren J-. Dupuytren's disease involving Guyon's canal. Chir Main. 2014;33(3):224-6.PubMedCrossRef
20.
Kraus R, Alzen G, Dreyer T, Szalay G, Schnettler R. Dupuytren's disease in children - case report and literature review. Handchir Mikrochir Plast Chir. 2012;44(3):175-7.CrossRef
21.
Mordus D, Miller M, Nesti L. Deep ulnar motor neuropathy from dupuytren contracture: A case report. PM R 2017;9(9):S215.CrossRef
22.
Spyropoulou G-, Pavlidis L, Mylothridis P, Zaraboukas T, Demiri E. Dupuytren in a child: rare presentation of a rare clinical entity. J Hand Surg (USA) 2016;41(12):e479.
23.
Germano CSB, Spitz M, Vasconcellos LFR. Primidone-related connective tissue disorders in essential tremor. Mov Disord. 2016;31:S328.
24.
Abogamal AF, Mahmoud E, Nassar Y, Hamed A, Amer AE, Abdulhakim S, et al. Painful hands in patients with type 2 diabetes mellitus, what ultrasound could tell us? Int J Rheum Dis. 2017;20:18.
25.
English C, Coughlan R, Carey J, Bergin D. Plantar and palmar fibromatosis: characteristic imaging features and role of MRI in clinical management. Rheumatology (Oxford). 2012;51(6):1134–6.CrossRef
26.
Yacoe ME, Bergman AG, Ladd AL, Hellman BH. Dupuytren's contracture: MR imaging findings and correlation between MR signal intensity and cellularity of lesions. AJR Am J Roentgenol. 1993;160(4):813–7.PubMedCrossRef
27.
Ulusoy A, Tikiz C, Örgüç Ş. Dupuytren’s contracture with rare bilateral thumb and little finger involvement demonstrated by ultrasound elastography. Arch Rheumatol. 2015;30(4):357–60.CrossRef
28.
Vanek P, Strömberg J, Fridén J, Aurell Y. Morphological patterns of the pretendinous cord in Dupuytren’s disease: a predictor of clinical outcome? J Plast Surg Hand Surg. 2018;52(4):240-4.PubMedCrossRef
29.
Elsahy NI. Doppler ultrasound detection of displaced neurovascular bundles in Dupuytren's contracture. Plast Reconstr Surg. 1976;57(1):104–5.PubMedCrossRef
30.
Uehara K, Miura T, Morizaki Y, Miyamoto H, Ohe T, Tanaka S. Ultrasonographic evaluation of displaced neurovascular bundle in Dupuytren disease. J Hand Surg Am. 2013;38(1):23–8.PubMedCrossRef
31.
Sakellariou VI, Brault J, Rizzo M. Ultrasound-assisted percutaneous needle fasciotomy for Dupuytren's contracture. Orthopedics. 2015;38(5):299–303.PubMedCrossRef
32.
Sampson S, Meng M, Schulte A, Trainor D, Montenegro R, Aufiero D. Management of Dupuytren contracture with ultrasound-guided lidocaine injection and needle aponeurotomy coupled with osteopathic manipulative treatment. J Am Osteopath Assoc. 2011;111(2):113–6.PubMed
33.
Croutzet P, Guinand R. Maintaining anticoagulant treatment in hand surgery - a review of 63 procedures. Hand Surg Rehabil. 2017;36:428.
34.
Croutzet P, Guinand R. Ultrasound-guided percutaneous hand surgery in clinic settings - a review of 513 patients. Hand Surg Rehabil. 2017;36:428.
35.
Leclere FM, Mathys L, Vogelin E. Collagenase injection in Dupuytren's disease, evaluation of the ultrasound assisted technique. Chir Main. 2014;33(3):196–203.PubMedCrossRef
36.
Christie WS, Puhl AA, Lucaciu OC. Cross-frictional therapy and stretching for the treatment of palmar adhesions due to Dupuytren’s contracture: a prospective case study. Man Ther. 2012;17(5):479–82.PubMedCrossRef
37.
Yin CY, Yu HM, Wang JP, Huang YC, Huang TF, Chang MC. Long-term follow-up of Dupuytren disease after injection of triamcinolone acetonide in Chinese patients in Taiwan. J Hand Surg Eur Vol. 2017;42(7):678–82.PubMedCrossRef
38.
Banks JS, Wolfson AH, Subhawong TK. T2 signal intensity as an imaging biomarker for patients with superficial Fibromatoses of the hands (Dupuytren's disease) and feet (Ledderhose disease) undergoing definitive electron beam irradiation. Skelet Radiol. 2018;47(2):243–51.CrossRef
39.
Stromberg J, Vanek P, Friden J, Aurell Y. Ultrasonographic examination of the ruptured cord after collagenase treatment or needle fasciotomy for Dupuytren's contracture. J Hand Surg Eur Vol. 2017;42(7):683–8.PubMedCrossRef
40.
Crivello KM, Potter HG, Moon ES, Rancy SK, Wolfe SW. Does collagenase injection disrupt or digest the Dupuytren’s cord: a magnetic resonance imaging study. J Hand Surg Eur Vol. 2016;41(6):614–20.PubMedCrossRef
41.
Werker PMN, Degreef I. Alternative and adjunctive treatments for Dupuytren disease. Hand Clin. 2018;34(3):367–75.PubMedCrossRef
42.
Nanchahal J, Ball C, Davidson D, Williams L, Sones W, McCann FE, et al. Anti-tumour necrosis factor therapy for Dupuytren's disease: a randomised dose response proof of concept phase 2a clinical trial. EBioMed. 2018;33:282–8.CrossRef
43.
Ketchum LD, Donahue TK. The injection of nodules of Dupuytren's disease with triamcinolone acetonide. J Hand Surg Am. 2000;25(6):1157–62.PubMedCrossRef
44.
Seegenschmiedt MH, Olschewski T, Guntrum F. Radiotherapy optimization in early-stage Dupuytren's contracture: first results of a randomized clinical study. Int J Radiat Oncol Biol Phys. 2001;49(3):785–98.PubMedCrossRef
45.
Rayan GM. Dupuytren disease: anatomy, pathology, presentation, and treatment. J Bone Joint Surg Am. 2007;89(1):189–98.PubMedCrossRef
46.
Nanchahal J, Ball C, Swettenham J, Dutton S, Barber V, Black J, et al. Study protocol: a multi-Centre, double blind, randomised, placebo-controlled, parallel group, phase II trial (RIDD) to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early Dupuytren's disease, with an embedded dose response study. Wellcome Open Res. 2017;6(2):37.CrossRef
47.
Badalamente MA, Hurst LC. Enzyme injection as nonsurgical treatment of Dupuytren's disease. J Hand Surg Am. 2000;25(4):629–36.PubMedCrossRef
48.
49.
Foucher G, Medina J, Navarro R. Percutaneous needle aponeurotomy. Complications and results. Chir Main. 2001;20(3):206–11.PubMedCrossRef
50.
Foucher G, Medina J, Navarro R. Percutaneous needle aponeurotomy: complications and results. J Hand Surg Br. 2003;28(5):427–31.PubMedCrossRef
51.
Nydick JA, Olliff BW, Garcia MJ, Hess AV, Stone JD. A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease. J Hand Surg Am. 2013;38(12):2377–80.PubMedCrossRef
52.
Pess GM, Pess RM, Pess RA. Results of needle aponeurotomy for Dupuytren contracture in over 1,000 fingers. J Hand Surg Am. 2012;37(4):651–6.PubMedCrossRef
53.
Scherman P, Jenmalm P, Dahlin LB. One-year results of needle fasciotomy and collagenase injection in treatment of Dupuytren's contracture: a two-Centre prospective randomized clinical trial. J Hand Surg Eur Vol. 2016;41(6):577–82.PubMedCrossRef
54.
van Rijssen AL, Werker PM. Percutaneous needle fasciotomy in dupuytren's disease. J Hand Surg Br. 2006;31(5):498–501.PubMedCrossRef
55.
Ball C, Verjee LS, Izadi D, Nanchahal J. A systematic review of non-surgical treatments for early dupuytren's disease. Hand Ther. 2016;21(1):39.
56.
Stromberg J, Ibsen Sorensen A, Friden J. Percutaneous needle fasciotomy versus collagenase treatment for Dupuytren contracture: a randomized controlled trial with a two-year follow-up. J Bone Joint Surg Am. 2018;100(13):1079–86.PubMedPubMedCentralCrossRef
57.
Park M, Park JS, Ahn SE, Ryu KN, Park SY, Jin W. Sonographic findings of common musculoskeletal diseases in patients with diabetes mellitus. Korean J Radiol. 2016;17(2):245-54.PubMedPubMedCentralCrossRef
58.
Robbin MR, Murphey MD, Temple HT, Kransdorf MJ, Choi JJ. Imaging of musculoskeletal fibromatosis. Radiographics. 2001;21(3):585-600.PubMedCrossRef
59.
Knobloch K. From nodules to chords in Dupuytren's contracture. MMW Fortschr Med. 2012;154(19):8, 40.
60.
Bianchi S, Della Santa D, Glauser T, Beaulieu J-, Van Aaken J. Sonography of masses of the wrist and hand. Am J Roentgenol. 2008;191(6):1767-75.PubMedCrossRef
61.
DiDomenico P, Middleton W. Sonographic evaluation of palpable superficial masses. Radiol Clin North Am. 2014;52(6):1205-305.PubMedCrossRef
62.
Faruch Bilfeld M, Lapègue F, Brun C, Bakouche S, Bayol M-, Chiavassa-Gandois H, et al. Tumors and pseudotumors of the hand: The role of imaging. Daign Intervent Imaging. 2015;96(12):1293-306.PubMedCrossRef
63.
Lee SA, Kim BH, Kim S-, Kim JN, Park S-, Choi K. Current status of ultrasonography of the finger. Ultrasonography. 2016;35(2):110-23.PubMedCrossRef
64.
Nagata S, Nishimura H, Abe T. MR Imaging of Soft-Tissue Tumors of the Upper Extremity. Magn Reson Imaging Clin North Am. 2015;23(3):457-68.PubMedCrossRef
65.
Pierucci A, Teixeira P, Zimmermann V, Sirveaux F, Rios M, Verhaegue J-, et al. Tumours and pseudotumours of the soft tissue in adults: Perspectives and current role of sonography. Daign Intervent Imaging. 2013;94(3):238-54.PubMedCrossRef
66.
Teh J, Whiteley G. MRI of soft tissue masses of the hand and wrist. Br J Radiol. 2007;80(949):47-63.PubMedCrossRef
67.
Walker EA, Fenton ME, Salesky JS, Murphey MD. Magnetic resonance imaging of benign soft tissue neoplasms in adults. Radiol Clin North Am. 2011;49(6):1197-217.PubMedCrossRef
Metadata
Title
Imaging for Dupuytren disease: a systematic review of the literature
Authors
Sanne Molenkamp
Roel J. M. van Straalen
Paul M. N. Werker
Dieuwke C. Broekstra
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2019
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-019-2606-0

Other articles of this Issue 1/2019

BMC Musculoskeletal Disorders 1/2019 Go to the issue

Research article

Green exercise and mg-ca-SO4 thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial

Research article

The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

Research article

Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry

Research article

3D spinal and rib cage predictors of brace effectiveness in adolescent idiopathic scoliosis

Research article

Intraoperative hypotension is a risk factor for postoperative acute kidney injury after femoral neck fracture surgery: a retrospective study

Study protocol

Effects of mobilisation with movement (MWM) on anatomical and clinical characteristics of chronic ankle instability: a randomised controlled trial protocol