Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2017

Open Access 01-12-2017 | Research article

RETRACTED ARTICLE: An evaluation of the potential consequences of drilling titanium and tantalum implants during surgery - a pilot study

Authors: Paweł Skowronek, Paweł Olszewski, Wojciech Święszkowski, Marcin Sibiński, Marek Synder, Michał Polguj

Published in: BMC Musculoskeletal Disorders | Issue 1/2017

Login to get access

Abstract

Background

The aim of the study was to evaluate the potential consequences of drilling titanium alloy (Ti) and tantalum (Ta) implants.

Methods

During an in vitro study, four holes were made in each of two spatially porous trabecular implants: one Ta and the other Ti alloy (Ti-6Al-7Nb). The weight and the volume of particles produced during the drilling were then measured using a Radwag XA 110/2X (USA) laboratory balance.

Results

The loss of mass of the Ti and Ta implants was respectively 1.26 g and 2.48 g, and the volume of free particles was respectively 280 mm3 and 149 mm3. The particles were recovered after each stage. Despite the use of 5 μm filters, around 0.6% of the total implant mass from both implants was not recovered after drilling (roughly 2% of the mass of the particles created).

Conclusion

It is technically difficult to make holes in Ti and Ta implants using standard surgical tools, and the process creates a significant amount of metal particles which cannot be removed, despite intensive flushing. This may have a potentially adverse influence on the survival of the implant and result in negative systemic consequences.
Literature
1.
go back to reference Meneghini RM, Ford KS, CH MC, Hahssen AD, Lewallen DG. Bone remodeling around porous metal cementless acetabular components. J Arthroplast. 2010;25:741–7.CrossRef Meneghini RM, Ford KS, CH MC, Hahssen AD, Lewallen DG. Bone remodeling around porous metal cementless acetabular components. J Arthroplast. 2010;25:741–7.CrossRef
2.
go back to reference Meneghini RM, Meyer C, Buckley CA, Hanssen AD, Lewallen DG. Mechanical stability of novel highly porous metal acetabular components in revision total hip arthroplasty. J Arthroplast. 2010;25:337–41.CrossRef Meneghini RM, Meyer C, Buckley CA, Hanssen AD, Lewallen DG. Mechanical stability of novel highly porous metal acetabular components in revision total hip arthroplasty. J Arthroplast. 2010;25:337–41.CrossRef
3.
go back to reference Levine BR, Sporer S, Poggie RA, Delia Valle CJ, Jacobs JJ. Experimental and clinical performance of porous tantalum in orthopedic surgery. Biomaterials. 2006;27:4671–81.CrossRef Levine BR, Sporer S, Poggie RA, Delia Valle CJ, Jacobs JJ. Experimental and clinical performance of porous tantalum in orthopedic surgery. Biomaterials. 2006;27:4671–81.CrossRef
4.
go back to reference Kamada T, Mashima N, Nakashima Y, Imai H, Takeba J, Miura H. Mid-term clinical and radiographic outcomes of porous tantalum modular acetabular components for hip dysplasia. J Arthroplast. 2015;30:607–10.CrossRef Kamada T, Mashima N, Nakashima Y, Imai H, Takeba J, Miura H. Mid-term clinical and radiographic outcomes of porous tantalum modular acetabular components for hip dysplasia. J Arthroplast. 2015;30:607–10.CrossRef
5.
go back to reference Papadelis EA, Karampinas PK, Kavroudakis E, Vlamis J, Polizois VD, Pneumaticos SG. Isolated Subtalar distraction Arthrodesis using porous tantalum: a pilot study. Foot Ankle Int. 2015; [Epub ahead of print] Papadelis EA, Karampinas PK, Kavroudakis E, Vlamis J, Polizois VD, Pneumaticos SG. Isolated Subtalar distraction Arthrodesis using porous tantalum: a pilot study. Foot Ankle Int. 2015; [Epub ahead of print]
6.
go back to reference Papi P, Jamshir S, Brauner E, Di Carlo S, Ceci A, Piccoli L, Pompa G. Clinical evaluation with 18 months follow-up of new PTTM enhanced dental implants in maxillo-facial post-oncological patients. Ann Stomatol (Roma). 2015;5:136–41.PubMedPubMedCentral Papi P, Jamshir S, Brauner E, Di Carlo S, Ceci A, Piccoli L, Pompa G. Clinical evaluation with 18 months follow-up of new PTTM enhanced dental implants in maxillo-facial post-oncological patients. Ann Stomatol (Roma). 2015;5:136–41.PubMedPubMedCentral
7.
go back to reference Sagherian BH, Claridge RJ. Salvage of failed total ankle replacement using tantalum trabecular metal: case series. Foot Ankle Int. 2015;36:318–24.CrossRef Sagherian BH, Claridge RJ. Salvage of failed total ankle replacement using tantalum trabecular metal: case series. Foot Ankle Int. 2015;36:318–24.CrossRef
8.
go back to reference Boureau F, Putman S, Arnould A, Dereudre G, Migaud H, Pasquier G. Tantalum cones and bone defects in revision total knee arthroplasty. Orthop Traumatol Surg Res. 2015;101:251–5.CrossRef Boureau F, Putman S, Arnould A, Dereudre G, Migaud H, Pasquier G. Tantalum cones and bone defects in revision total knee arthroplasty. Orthop Traumatol Surg Res. 2015;101:251–5.CrossRef
9.
go back to reference Fernandez-Fairen M, Hernández-Vaquero D, Murcia A, Torres A, Llopis R. Trabecular metal in total knee arthroplasty associated with higher knee scores: a randomized controlled trial. Clin Orthop Relat Res. 2013;471:3543–53.CrossRef Fernandez-Fairen M, Hernández-Vaquero D, Murcia A, Torres A, Llopis R. Trabecular metal in total knee arthroplasty associated with higher knee scores: a randomized controlled trial. Clin Orthop Relat Res. 2013;471:3543–53.CrossRef
10.
go back to reference Bobyn JD, Stackpool GJ, Hacking SA, Tanzer M, Krygier JJ. Characteristics of bone ingrowth and interface mechanics of a new porous tantalum biomaterial. J Bone Joint Surg Br. 1999;81:907–14.CrossRef Bobyn JD, Stackpool GJ, Hacking SA, Tanzer M, Krygier JJ. Characteristics of bone ingrowth and interface mechanics of a new porous tantalum biomaterial. J Bone Joint Surg Br. 1999;81:907–14.CrossRef
11.
go back to reference Hacking SA, Bobyn JD, Toh K, Tänzer M, Krygier JJ. Fibrous tissue ingrowth and attachment to porous tantalum. J Biomed Mater Res. 2000;52:631–8.CrossRef Hacking SA, Bobyn JD, Toh K, Tänzer M, Krygier JJ. Fibrous tissue ingrowth and attachment to porous tantalum. J Biomed Mater Res. 2000;52:631–8.CrossRef
12.
go back to reference Mostardi RA, Pentello A, Kovacik MW, Askew MJ. Prosthetic metals have a variable necrotic threshold in human fibroblasts: an in vitro study. J Biomed Mater Res. 2002;59(4):605–10.CrossRef Mostardi RA, Pentello A, Kovacik MW, Askew MJ. Prosthetic metals have a variable necrotic threshold in human fibroblasts: an in vitro study. J Biomed Mater Res. 2002;59(4):605–10.CrossRef
13.
go back to reference Mostardi RA, Meerbaum SO, Kovacik MW, Gradisar IA Jr. Response of human fibroblasts to tantalum and titanium in cell culture. Biomed Sci Instrum. 1997;33:514–8.PubMed Mostardi RA, Meerbaum SO, Kovacik MW, Gradisar IA Jr. Response of human fibroblasts to tantalum and titanium in cell culture. Biomed Sci Instrum. 1997;33:514–8.PubMed
14.
go back to reference Grohowski J. Praxis technology: taking the next step in the commercialisation of high performance TiMIM alloys. Powder Injection Moulding International. 2016;10(2):63–9. Grohowski J. Praxis technology: taking the next step in the commercialisation of high performance TiMIM alloys. Powder Injection Moulding International. 2016;10(2):63–9.
15.
go back to reference Lehmann I, Sack U, Lehmann J. Metal ions affecting the immune system. Met Ions Life Sci. 2011;8:157–85.PubMed Lehmann I, Sack U, Lehmann J. Metal ions affecting the immune system. Met Ions Life Sci. 2011;8:157–85.PubMed
16.
go back to reference Billi F, Campbell P. Nanotoxicology of metal wear particles in total joint arthroplasty: a review of current concepts. J Appl Biomater Biomech. 2010;8:1–6.PubMed Billi F, Campbell P. Nanotoxicology of metal wear particles in total joint arthroplasty: a review of current concepts. J Appl Biomater Biomech. 2010;8:1–6.PubMed
17.
go back to reference Gratton SE, Ropp PA, Pohlhaus PD, Luft JC, Madden VJ, Napier ME, DeS-imone JM. The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci U S A. 2008;105(33):11613–8.CrossRef Gratton SE, Ropp PA, Pohlhaus PD, Luft JC, Madden VJ, Napier ME, DeS-imone JM. The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci U S A. 2008;105(33):11613–8.CrossRef
18.
go back to reference Papageorgiou I, Yin Z, Ladon D, et al. Genotoxic effects of particles of surgical cobalt chrome alloy on human cells of different age in vitro. Mutat Res. 2007;619:45–58.CrossRef Papageorgiou I, Yin Z, Ladon D, et al. Genotoxic effects of particles of surgical cobalt chrome alloy on human cells of different age in vitro. Mutat Res. 2007;619:45–58.CrossRef
19.
go back to reference Madden EF, Fowler BA. Mechanisms of nephrotoxicity from metal combinations: a review. Drug Chem Toxicol. 2000;23(1):1–12.CrossRef Madden EF, Fowler BA. Mechanisms of nephrotoxicity from metal combinations: a review. Drug Chem Toxicol. 2000;23(1):1–12.CrossRef
20.
go back to reference Evrard L, Waroquier D, Parent D. Allergies to dental metals. Titanium: a new allergen. Rev Med Brux. 2010;31(1):44–9.PubMed Evrard L, Waroquier D, Parent D. Allergies to dental metals. Titanium: a new allergen. Rev Med Brux. 2010;31(1):44–9.PubMed
21.
go back to reference Goutam M, Giriyapura C, Mishra SK, Gupta S. Titanium allergy: a literature review. Indian J Dermatol. 2014;59(6):630.CrossRef Goutam M, Giriyapura C, Mishra SK, Gupta S. Titanium allergy: a literature review. Indian J Dermatol. 2014;59(6):630.CrossRef
Metadata
Title
RETRACTED ARTICLE: An evaluation of the potential consequences of drilling titanium and tantalum implants during surgery - a pilot study
Authors
Paweł Skowronek
Paweł Olszewski
Wojciech Święszkowski
Marcin Sibiński
Marek Synder
Michał Polguj
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2017
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-017-1784-x

Other articles of this Issue 1/2017

BMC Musculoskeletal Disorders 1/2017 Go to the issue