Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2015

Open Access 01-12-2015 | Research article

Musculoskeletal pain in people with and without type 2 diabetes in Taiwan: a population-based, retrospective cohort study

Authors: Lee-Wen Pai, Chin-Tun Hung, Shu-Fen Li, Li-Li Chen, Yueh- Chin Chung, Hsin-Li Liu

Published in: BMC Musculoskeletal Disorders | Issue 1/2015

Login to get access

Abstract

Background

Musculoskeletal pain in people with type 2 diabetes is a common issue even to this day. The study aimed to explore the 10-year cumulative incidence of musculoskeletal pain, the mean number of doctor visits for musculoskeletal pain, and the mean number of doctor visits for musculoskeletal pain by location in people with type 2 diabetes, compared with respective values for people without diabetes.

Methods

The study utilized a population-based retrospective cohort study design. The subjects were randomly obtained from the Taiwan National Health Insurance Research Database. The diabetic group included 6586 people with type 2 diabetes aged 18–50 years, while the non-diabetic group consisted of 32,930 age- and sex-matched people. Based on the medical records of individuals with musculoskeletal pain in the two groups from 2001 to 2010, the 10-year cumulative incidence of musculoskeletal pain, the mean number of doctor visits for musculoskeletal pain, and the mean number of doctor visits for musculoskeletal pain by location were calculated and compared, with the aim of identifying differences between the two groups.

Results

Showed that people in the diabetic group had a higher 10-year cumulative incidence of and a higher mean number of doctor visits for musculoskeletal pain than the non-diabetic group (p < 0.05). The relative risk (RR) of the 10-year cumulative incidence of musculoskeletal pain in the two groups was the highest (RR = 1.39) for people between 30 and 39 years of age. The mean number of doctor visits for musculoskeletal pain by location was significantly different between the two groups. However, the mean number of doctor visits for limb pain registered the largest difference between the two groups.

Conclusion

People with type 2 diabetes aged 18–50 years had a higher 10-year cumulative incidence of and a higher mean number of doctor visits for musculoskeletal pain than the non-diabetic group. Musculoskeletal pain might directly or indirectly interfere with or decrease the physical activity levels of people with diabetes. Therefore, it is important to detect and treat musculoskeletal pain early in order to promote physical activity and optimize blood sugar control.
Literature
1.
go back to reference Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010. a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095–128.CrossRefPubMed Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010. a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095–128.CrossRefPubMed
4.
go back to reference American Diabetes Association. Standards of medical care in diabetes-2010. Diabetes Care. 2010;1:S11–61.CrossRef American Diabetes Association. Standards of medical care in diabetes-2010. Diabetes Care. 2010;1:S11–61.CrossRef
5.
go back to reference Reeves ND, Najafi B, Crews RT, Bowling FL. Aging and type 2 diabetes. consequences for motor control, musculoskeletal function, and whole-body movement. J Aging Res. 2013;doi: 10.1155/2013/508756. Reeves ND, Najafi B, Crews RT, Bowling FL. Aging and type 2 diabetes. consequences for motor control, musculoskeletal function, and whole-body movement. J Aging Res. 2013;doi: 10.​1155/​2013/​508756.
8.
go back to reference Wang J, Yuan S, Zhu L, Fu H, Li H, Hu G, et al. Effects of impaired fasting glucose and impaired glucose tolerance on predicting incident type 2 diabetes in a Chinese population with high post-prandial glucose. Diabetes Res Clin Pract. 2004;66:183–91.CrossRefPubMed Wang J, Yuan S, Zhu L, Fu H, Li H, Hu G, et al. Effects of impaired fasting glucose and impaired glucose tolerance on predicting incident type 2 diabetes in a Chinese population with high post-prandial glucose. Diabetes Res Clin Pract. 2004;66:183–91.CrossRefPubMed
9.
go back to reference Cichosz SL, Fleischer J, Hoeyem P, Laugesen E, Poulsen PL, Christiansen JS, et al. Objective measurements of activity patterns in people with newly diagnosed Type 2 diabetes demonstrate a sedentary lifestyle. Diabetic Med. 2013;30:1063–6.CrossRefPubMed Cichosz SL, Fleischer J, Hoeyem P, Laugesen E, Poulsen PL, Christiansen JS, et al. Objective measurements of activity patterns in people with newly diagnosed Type 2 diabetes demonstrate a sedentary lifestyle. Diabetic Med. 2013;30:1063–6.CrossRefPubMed
10.
go back to reference Rosenbloom AL, Silverstein JH. Connective tissue and joint disease in diabetes mellitus. Endocrinal Metab Clin North Am. 1996;25:473–83.CrossRef Rosenbloom AL, Silverstein JH. Connective tissue and joint disease in diabetes mellitus. Endocrinal Metab Clin North Am. 1996;25:473–83.CrossRef
11.
go back to reference Browne DL, McCrae FC, Shaw KM. Musculoskeletal disease in diabetes. Practical Diabetes Int. 2001;18:62–4.CrossRef Browne DL, McCrae FC, Shaw KM. Musculoskeletal disease in diabetes. Practical Diabetes Int. 2001;18:62–4.CrossRef
12.
go back to reference Arkkila PE, Gautier JF. Musculoskeletal disorders in diabetes mellitus: an update. Best Prac Res Clin Rheumatol. 2003;17:945–70.CrossRef Arkkila PE, Gautier JF. Musculoskeletal disorders in diabetes mellitus: an update. Best Prac Res Clin Rheumatol. 2003;17:945–70.CrossRef
13.
go back to reference Sherif EM, Abd Al Aziz MM, Elbarbary NS, Ahmed AM. Insulin-like growth factor-1 in correlation with bone mineral density among Egyptian adolescents with type 1 diabetes mellitus. Int J Diabetes in Dev Ctries. 2011;31:104–12.CrossRef Sherif EM, Abd Al Aziz MM, Elbarbary NS, Ahmed AM. Insulin-like growth factor-1 in correlation with bone mineral density among Egyptian adolescents with type 1 diabetes mellitus. Int J Diabetes in Dev Ctries. 2011;31:104–12.CrossRef
14.
go back to reference Esteghamati A, Etemad K, Koohpayehzadeh J, Abbasi M, Meysamie A, Noshad S, et al. Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005–2011. Diabetes Res Clin Pract. 2014;103:319–27.CrossRefPubMed Esteghamati A, Etemad K, Koohpayehzadeh J, Abbasi M, Meysamie A, Noshad S, et al. Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005–2011. Diabetes Res Clin Pract. 2014;103:319–27.CrossRefPubMed
15.
go back to reference Lee PH. Association between Adolescents' Physical Activity and Sedentary Behaviors with Change in BMI and Risk of Type 2 Diabetes. PLoS One. 2014;9, e110732.CrossRefPubMedPubMedCentral Lee PH. Association between Adolescents' Physical Activity and Sedentary Behaviors with Change in BMI and Risk of Type 2 Diabetes. PLoS One. 2014;9, e110732.CrossRefPubMedPubMedCentral
16.
go back to reference Molsted S, Tibler J, Snorgaard O. Musculoskeletal pain in patients with type 2 diabetes. Diabetes Res Clin Pract. 2012;96:135–40.CrossRefPubMed Molsted S, Tibler J, Snorgaard O. Musculoskeletal pain in patients with type 2 diabetes. Diabetes Res Clin Pract. 2012;96:135–40.CrossRefPubMed
17.
go back to reference Zamani B, Matini SM, Jamali R, Taghadosi M. Frequency of musculoskeletal complications among the diabetic patients referred to Kashan diabetes center during 2009–10. Journal of Kashan University of Medical Sciences. 2011;15:225–31. Zamani B, Matini SM, Jamali R, Taghadosi M. Frequency of musculoskeletal complications among the diabetic patients referred to Kashan diabetes center during 2009–10. Journal of Kashan University of Medical Sciences. 2011;15:225–31.
18.
go back to reference Slater M, Perruccio AV, Badley EM. Musculoskeletal comorbidities in cardiovascular disease, diabetes and respiratory disease: the impact on activity limitations; a representative population-based study. BMC Public Health. 2011;11:77.CrossRefPubMedPubMedCentral Slater M, Perruccio AV, Badley EM. Musculoskeletal comorbidities in cardiovascular disease, diabetes and respiratory disease: the impact on activity limitations; a representative population-based study. BMC Public Health. 2011;11:77.CrossRefPubMedPubMedCentral
19.
go back to reference Hoff OM, Midthjell K, Zwart JA, Hagen K. The association between diabetes mellitus, glucose, and chronic musculoskeletal complaints: Results from the Nord-Trøndelag Health Study. BMC Musculoskelet Disord. 2008;9:160.CrossRefPubMedPubMedCentral Hoff OM, Midthjell K, Zwart JA, Hagen K. The association between diabetes mellitus, glucose, and chronic musculoskeletal complaints: Results from the Nord-Trøndelag Health Study. BMC Musculoskelet Disord. 2008;9:160.CrossRefPubMedPubMedCentral
22.
go back to reference Wilkie R, Tajar A, McBeth J. The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study. PLoS One. 2013;8:1–11.CrossRef Wilkie R, Tajar A, McBeth J. The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study. PLoS One. 2013;8:1–11.CrossRef
23.
go back to reference Lekpa FK, Ndongo S, Ka O, Zeba D, Compaoré C, Pouye A, et al. Socio-demographic and clinical profile of chronic pain with neuropathic characteristics in sub-Saharan African elderly. Eur J Pain. 2013;17:939–43.CrossRefPubMed Lekpa FK, Ndongo S, Ka O, Zeba D, Compaoré C, Pouye A, et al. Socio-demographic and clinical profile of chronic pain with neuropathic characteristics in sub-Saharan African elderly. Eur J Pain. 2013;17:939–43.CrossRefPubMed
24.
go back to reference Stommen NC, Verbunt JA, Gorter SL, Goossens ME. Physical activity and disability among adolescents and young adults with non-specific musculoskeletal pain. Disabil Rehabil. 2012;34:1438–43.CrossRefPubMed Stommen NC, Verbunt JA, Gorter SL, Goossens ME. Physical activity and disability among adolescents and young adults with non-specific musculoskeletal pain. Disabil Rehabil. 2012;34:1438–43.CrossRefPubMed
25.
go back to reference van Wilgen P, Beetsma A, Neels H, Roussel N, Nijs J. Physical therapists should integrate illness perceptions in their assessment in patients with chronic musculoskeletal pain; a qualitative analysis. Manual Therapy. 2014;19:229–34.CrossRefPubMed van Wilgen P, Beetsma A, Neels H, Roussel N, Nijs J. Physical therapists should integrate illness perceptions in their assessment in patients with chronic musculoskeletal pain; a qualitative analysis. Manual Therapy. 2014;19:229–34.CrossRefPubMed
26.
go back to reference Mathew AJ, Nair JB, Pillai SS. Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India. Int J Rheum Dis. 2011;14:55–60.CrossRefPubMed Mathew AJ, Nair JB, Pillai SS. Rheumatic-musculoskeletal manifestations in type 2 diabetes mellitus patients in south India. Int J Rheum Dis. 2011;14:55–60.CrossRefPubMed
28.
go back to reference Ramírez-Maestre C, Esteve R. The role of sex/gender in the experience of pain: resilience, fear, and acceptance as central variables in the adjustment of men and women with chronic pain. J Pain. 2014;15:608–18.CrossRefPubMed Ramírez-Maestre C, Esteve R. The role of sex/gender in the experience of pain: resilience, fear, and acceptance as central variables in the adjustment of men and women with chronic pain. J Pain. 2014;15:608–18.CrossRefPubMed
29.
go back to reference Racine M, Tousignant-Laflamme Y, Kloda LA, Dion D, Dupuis G, Choinière MA. Systematic literature review of 10 years of research on sex/gender and experimental pain perception - Part 1: Are there really differences between women and men? Pain. 2012;153:602–18.CrossRefPubMed Racine M, Tousignant-Laflamme Y, Kloda LA, Dion D, Dupuis G, Choinière MA. Systematic literature review of 10 years of research on sex/gender and experimental pain perception - Part 1: Are there really differences between women and men? Pain. 2012;153:602–18.CrossRefPubMed
30.
go back to reference Yu WC, Fang PL, Ming Y. A customer profile analysis of a regional hospital in southern Taiwan. Yi Bao Yan Jiu Za Zhi. 2006;2:9–18. Yu WC, Fang PL, Ming Y. A customer profile analysis of a regional hospital in southern Taiwan. Yi Bao Yan Jiu Za Zhi. 2006;2:9–18.
32.
33.
go back to reference Eivazi M, Abadi L. Low back pain in diabetes mellitus and importance of preventive approach. Health Promot Perspect. 2012;2:80–8.PubMedPubMedCentral Eivazi M, Abadi L. Low back pain in diabetes mellitus and importance of preventive approach. Health Promot Perspect. 2012;2:80–8.PubMedPubMedCentral
34.
go back to reference Lin HW, Wang KH, Lin HC, Lin HC. Increased risk of acute myocardial infarction in patients with psoriasis: a 5-year population-based study in Taiwan. J Am Acad Dermatol. 2011;64:495–501.CrossRefPubMed Lin HW, Wang KH, Lin HC, Lin HC. Increased risk of acute myocardial infarction in patients with psoriasis: a 5-year population-based study in Taiwan. J Am Acad Dermatol. 2011;64:495–501.CrossRefPubMed
Metadata
Title
Musculoskeletal pain in people with and without type 2 diabetes in Taiwan: a population-based, retrospective cohort study
Authors
Lee-Wen Pai
Chin-Tun Hung
Shu-Fen Li
Li-Li Chen
Yueh- Chin Chung
Hsin-Li Liu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2015
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-015-0819-4

Other articles of this Issue 1/2015

BMC Musculoskeletal Disorders 1/2015 Go to the issue