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Published in: BMC Musculoskeletal Disorders 1/2015

Open Access 01-12-2015 | Research article

Effect of distraction osteogenesis in patient with tibial shortening after initial union of Congenital Pseudarthrosis of the Tibia (CPT): a preliminary study

Authors: Guang-hui Zhu, Hai-bo Mei, Rong-guo He, Kun Liu, Jin Tang, Jiang-yan Wu

Published in: BMC Musculoskeletal Disorders | Issue 1/2015

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Abstract

Background

The purpose of our retrospective study was to evaluate the preliminary result of distraction osteogenesis in patient with tibial shortening after initial union of Congenital Pseudarthrosis of the Tibia (CPT).

Methods

All the CPT cases with tibial shortening after initial union managed by proximal tibial lengthening using Ilizarov technique were identified. All the patient charts and radiograms were reviewed.

Results

Between March 2007 and January 2012, 11 CPT cases were included with an average follow-up of 41 months (range, 34–51 months). The mean age at surgery was 8.5 years (range, 3.9–14.5y). The average length of discrepancy was 5.6 cm (range, 2.0–8.2 cm). Eight (8) cases had radiological findings of proximal tibial dysplasia, while the other 3 cases had not. The average distraction length gained was 5.3 cm (range, 3.5–8.0 cm) with a mean elongation rate of 21.4 % (range, 15–30 %). The Healing Index (HI) was 63.1 d/cm (range, 47–77 d/cm). In the 8 patients with proximal tibial dysplasia, 5 cases had lateral callus, 3 had central callus, and poor bone regeneration was observed in all of them with an average HI of 67 d/cm. In the other 3 patients without proximal tibial dysplasia, concave shaped callus was identified with an average HI of 52.7 d/cm. None of the patients had re-fracture, nonunion, axis deviation or angulation of the distraction area. Ankle joint stiffness was found in 2 of the patients. No evidence of knee contracture was detected. There were 5 cases with pin-tract infection which was managed by pin-tract nurse and oral administration of antibiotics.

Conclusions

We concluded that proximal tibial lengthening after initial union of CPT was effective for management of tibial shortening, however it was characterized by poor bone regeneration with different types of callus from normal, greater healing index and prolonged fixator wearing. We recommended that tibial lengthening could be considered when the limb length discrepancy (LLD) was more than 4 cm in younger children after primary union of CPT.
Literature
1.
go back to reference Hefti F, Bollini G, Dungl P, Fixsen J, Grill F, Ippolito E, et al. Congenital pseudarthrosis of the tibia: history, etiology, classification, and epidemiologic data. J Pediatr Orthop B. 2000;9(1):11–5.CrossRefPubMed Hefti F, Bollini G, Dungl P, Fixsen J, Grill F, Ippolito E, et al. Congenital pseudarthrosis of the tibia: history, etiology, classification, and epidemiologic data. J Pediatr Orthop B. 2000;9(1):11–5.CrossRefPubMed
2.
go back to reference Thabet AM, Paley D, Kocaoglu M, Eralp L, Herzenberg JE, Ergin ON. Periosteal grafting for congenital pseudarthrosis of the tibia: a preliminary report. Clin Orthop Relat Res. 2008;466(12):2981–94.CrossRefPubMedPubMedCentral Thabet AM, Paley D, Kocaoglu M, Eralp L, Herzenberg JE, Ergin ON. Periosteal grafting for congenital pseudarthrosis of the tibia: a preliminary report. Clin Orthop Relat Res. 2008;466(12):2981–94.CrossRefPubMedPubMedCentral
3.
go back to reference Shah H, Doddabasappa SN, Joseph B. Congenital pseudarthrosis of the tibia treated with intramedullary rodding and cortical bone grafting: a follow-up study at skeletal maturity. J Pediatr Orthop. 2011;31(1):79–88.CrossRefPubMed Shah H, Doddabasappa SN, Joseph B. Congenital pseudarthrosis of the tibia treated with intramedullary rodding and cortical bone grafting: a follow-up study at skeletal maturity. J Pediatr Orthop. 2011;31(1):79–88.CrossRefPubMed
4.
go back to reference Pannier S, Pejin Z, Dana C, Masquelet AC, Glorion C. Induced membrane technique for the treatment of congenital pseudarthrosis of the tibia: preliminary results of five cases. J Child Orthop. 2013;7(6):477–85.CrossRefPubMedPubMedCentral Pannier S, Pejin Z, Dana C, Masquelet AC, Glorion C. Induced membrane technique for the treatment of congenital pseudarthrosis of the tibia: preliminary results of five cases. J Child Orthop. 2013;7(6):477–85.CrossRefPubMedPubMedCentral
5.
go back to reference Khan T, Joseph B. Controversies in the management of congenital pseudarthrosis of the tibia and fibula. Bone Joint J. 2013;95(8):1027–34.CrossRefPubMed Khan T, Joseph B. Controversies in the management of congenital pseudarthrosis of the tibia and fibula. Bone Joint J. 2013;95(8):1027–34.CrossRefPubMed
6.
7.
go back to reference Inan M, El Rassi G, Riddle EC, Kumar SJ. Residual deformities following successful initial bone union in congenital pseudarthrosis of the tibia. J Pediatr Orthop. 2006;26(3):393–9.CrossRefPubMed Inan M, El Rassi G, Riddle EC, Kumar SJ. Residual deformities following successful initial bone union in congenital pseudarthrosis of the tibia. J Pediatr Orthop. 2006;26(3):393–9.CrossRefPubMed
8.
go back to reference Kristiansen LP, Steen H, Terjesen T. Residual challenges after healing of congenital pseudarthrosis in the tibia. Clin Orthop Relat Res. 2003;414:228–37.CrossRefPubMed Kristiansen LP, Steen H, Terjesen T. Residual challenges after healing of congenital pseudarthrosis in the tibia. Clin Orthop Relat Res. 2003;414:228–37.CrossRefPubMed
9.
go back to reference Cho TJ, Choi IH, Lee KS, Lee SM, Chung CY, Yoo WJ, et al. Proximal tibial lengthening by distraction osteogenesis in congenital pseudarthrosis of the tibia. J Pediatr Orthop. 2007;27(8):915–20.CrossRefPubMed Cho TJ, Choi IH, Lee KS, Lee SM, Chung CY, Yoo WJ, et al. Proximal tibial lengthening by distraction osteogenesis in congenital pseudarthrosis of the tibia. J Pediatr Orthop. 2007;27(8):915–20.CrossRefPubMed
10.
go back to reference Vlad C, Gavriliu TS, Georgescu I, Dan D, Parvan A, Burnei G. Bone transport with the lengthening through the physis in patients having congenital pseudarthrosis of tibia - short-term results. J Med Life. 2013;6(3):266–71.PubMedPubMedCentral Vlad C, Gavriliu TS, Georgescu I, Dan D, Parvan A, Burnei G. Bone transport with the lengthening through the physis in patients having congenital pseudarthrosis of tibia - short-term results. J Med Life. 2013;6(3):266–71.PubMedPubMedCentral
11.
go back to reference Mathieu L, Vialle R, Thevenin-Lemoine C, Mary P, Damsin JP. Association of Ilizarov’s technique and intramedullary rodding in the treatment of congenital pseudarthrosis of the tibia. J Child Orthop. 2008;2(6):449–55.CrossRefPubMedPubMedCentral Mathieu L, Vialle R, Thevenin-Lemoine C, Mary P, Damsin JP. Association of Ilizarov’s technique and intramedullary rodding in the treatment of congenital pseudarthrosis of the tibia. J Child Orthop. 2008;2(6):449–55.CrossRefPubMedPubMedCentral
12.
go back to reference Ohnishi I, Sato W, Matsuyama J, Yajima H, Haga N, Kamegaya M, et al. Treatment of congenital pseudarthrosis of the tibia: a multicenter study in Japan. J Pediatr Orthop. 2005;25:219–24.CrossRefPubMed Ohnishi I, Sato W, Matsuyama J, Yajima H, Haga N, Kamegaya M, et al. Treatment of congenital pseudarthrosis of the tibia: a multicenter study in Japan. J Pediatr Orthop. 2005;25:219–24.CrossRefPubMed
13.
go back to reference Li R, Saleh M, Yang L, Coulton L. Radiographic classification of osteogenesis during bone distraction. J Orthop Res. 2006;24(3):339–47.CrossRefPubMed Li R, Saleh M, Yang L, Coulton L. Radiographic classification of osteogenesis during bone distraction. J Orthop Res. 2006;24(3):339–47.CrossRefPubMed
14.
go back to reference Noonan KJ, Leyes M, Forriol F, Canadell J. Distraction osteogenesis of the lower extremity with use of monolateral external fixation. A study of two hundred and sixty-one femora and tibiae. J Bone Joint Surg Am. 1998;80(6):793–806.PubMed Noonan KJ, Leyes M, Forriol F, Canadell J. Distraction osteogenesis of the lower extremity with use of monolateral external fixation. A study of two hundred and sixty-one femora and tibiae. J Bone Joint Surg Am. 1998;80(6):793–806.PubMed
Metadata
Title
Effect of distraction osteogenesis in patient with tibial shortening after initial union of Congenital Pseudarthrosis of the Tibia (CPT): a preliminary study
Authors
Guang-hui Zhu
Hai-bo Mei
Rong-guo He
Kun Liu
Jin Tang
Jiang-yan Wu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2015
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-015-0680-5

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