Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
BMC Public Health
Published in: BMC Public Health 1/2019

Open Access 01-12-2019 | Research article

Association between frailty and the combination of physical activity level and sedentary behavior in older adults

Authors: Venicius Dantas da Silva, Sheilla Tribess, Joilson Meneguci, Jeffer Eidi Sasaki, Cíntia Aparecida Garcia-Meneguci, José Ailton Oliveira Carneiro, Jair Sindra Virtuoso Jr

Published in: BMC Public Health | Issue 1/2019

Login to get access

Abstract

Background

The combined association of physical activity and sedentary behavior with adverse health factors is not yet clear in the literature. A combined analysis of physical activity level and sedentary behavior may provide evidence of the interrelation between these behavioral variables and the frailty syndrome. Thus, the aim of this study was to examine the relationship between physical activity level, sedentary behavior and frailty in older adults.

Methods

In this study, we evaluated 457 older adults (age range = 60 to 96 years old) from the Longitudinal Study of the Elderly Health of Alcobaça, Bahia. The frailty condition was defined by the presence of three or more of the following criteria: unintentional weight loss, slow walking speed measured over a 4.57 m test, a reduction of manual grip strength and exhaustion. Based upon these criteria, participants were classified as non-frail or frail. Physical activity level and time spent in sedentary behavior were assessed with the International Questionnaire of Physical Activity. Descriptive statistics were used to characterize the sample. To examine the combined association of physical activity and sedentary behavior with frailty, chi-square and Poisson regression tests were used. Statistical significance was defined as p ≤ 0.05.

Results

The prevalence of frailty was 8.8% (n = 40), with higher prevalence observed with increasing age. Low physical activity level combined with excessive time spent in sedentary behavior (physical activity level < 150 min/wk. and sedentary behavior ≥540 min/day) was associated with frailty, resulting in a prevalence ratio of 2.83 (95% CI, 1.23 to 6.52).

Conclusion

Frailty is more prevalent among older adults who exhibit insufficient levels of physical activity combined with a great amount of time spent in sedentary behavior, even when adjusted for sociodemographic factors.
Literature
1.
Ensrud KE, Ewing SK, Cawthon PM, Fink HA, Taylor BC, Cauley JA, et al. A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J Am Geriatr Soc. 2009;57:492–8.CrossRefPubMedCentralPubMed
2.
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–56.CrossRefPubMed
3.
Rockwood MR, MacDonald E, Sutton E, Rockwood K, Baron M, Canadian Scleroderma Research Group. Frailty index to measure health status in people with systemic sclerosis. J Rheumatol. 2014;41:698–705.CrossRefPubMed
4.
5.
Blodgett J, Theou O, Kirkland S, Andreou P, Rockwood K. Frailty in relation to sedentary behaviours and moderate-vigorous intensity physical activity. Rev Clin Gerontol. 2014;24:239–54.CrossRef
6.
Blodgett J, Theou O, Kirkland S, Andreou P, Rockwood K. The association between sedentary behaviour, moderate–vigorous physical activity and frailty in NHANES cohorts. Maturitas. 2015;80:187–91.CrossRefPubMed
7.
del Pozo-Cruz B, Mañas A, Martín-García M, Marín-Puyalto J, García-García FJ, Rodriguez-Mañas L, et al. Frailty is associated with objectively assessed sedentary behaviour patterns in older adults: evidence from the Toledo study for healthy aging (TSHA). PLoS One. 2017;12:e0183911.CrossRefPubMedCentralPubMed
8.
Paulo TRS, Tribess S, Sasaki JE, Meneguci J, Martins CA, Freitas IF, et al. A cross-sectional study of the relationship of physical activity with depression and cognitive deficit in older adults. J Aging Phys Act. 2016;24:311–21.CrossRef
9.
Virtuoso JS Jr, Tribess S, Paulo TRSD, Martins CA, Romo-Perez V. Physical activity as an indicator of predictive functional disability in elderly. Rev Lat Am Enfermagem. 2012;20:259–65.CrossRef
10.
Kohl HW, Craig CL, Lambert EV, Inoue S, Alkandari JR, Leetongin G, et al. The pandemic of physical inactivity: global action for public health. Lancet. 2012;380:294–305.CrossRefPubMed
11.
Althoff T, Sosič R, Hicks JL, King AC, Delp SL, Leskovec J. Large-scale physical activity data reveal worldwide activity inequality. Nature. 2017;547:336–9.CrossRefPubMedCentralPubMed
12.
Matthews CE, Chen KY, Freedson PS, Buchowski MS, Beech BM, Pate RR, et al. Amount of time spent in sedentary behaviors in the United States, 2003-2004. Am J Epidemiol. 2008;167:875–81.CrossRefPubMed
13.
Charansonney OL. Physical activity and aging: a life-long story. Discov Med. 2011;12:177–85.PubMed
14.
Li C-L, Chu S-J, Sheu J-T, LY-G H. Impact of physical activity on hospitalization in older adults: a nationwide cohort from Taiwan. Arch Gerontol Geriatr. 2011;53:141–5.CrossRefPubMed
15.
Savela SL, Koistinen P, Stenholm S, Tilvis RS, Strandberg AY, Pitkala KH, et al. Leisure-time physical activity in midlife is related to old age frailty. J Gerontol A Biol Sci Med Sci. 2013;68:1433–8.CrossRefPubMed
16.
Peterson MJ, Giuliani C, Morey MC, Pieper CF, Evenson KR, Mercer V, et al. Physical activity as a preventative factor for frailty: the health, aging, and body composition study. J Gerontol A Biol Sci Med Sci. 2009;64A:61–8.CrossRefPubMedCentral
17.
Dunlop DD, Song J, Arntson EK, Semanik PA, Lee J, Chang RW, et al. Sedentary time in US older adults associated with disability in activities of daily living independent of physical activity. J Phys Act Health. 2015;12:93–101.CrossRefPubMed
18.
Virtuoso JS Jr, Roza LB, Tribess S, Meneguci J, Mendes EL, Pegorari MS, et al. Time spent sitting is associated with changes in biomarkers of frailty in hospitalized older adults: a cross sectional study. Front Physiol. 2017;8:505.CrossRef
19.
20.
Theou O, Blodgett JM, Godin J, Rockwood K. Association between sedentary time and mortality across levels of frailty. Can Med Assoc J. 2017;189:E1056–64.CrossRef
21.
Healy GN, Wijndaele K, Dunstan DW, Shaw JE, Salmon J, Zimmet PZ, et al. Objectively measured sedentary time, physical activity, and metabolic risk: the Australian diabetes, obesity and lifestyle study (AusDiab). Diabetes Care. 2008;31:369–71.CrossRefPubMed
22.
Koster A, Caserotti P, Patel KV, Matthews CE, Berrigan D, Van Domelen DR, et al. Association of sedentary time with mortality independent of moderate to vigorous physical activity. PLoS One. 2012;7:e37696.CrossRefPubMedCentralPubMed
23.
Schwenk M, Mohler J, Wendel C, D'Huyvetter K, Fain M, Taylor-Piliae R, et al. Wearable sensor-based in-home assessment of gait, balance, and physical activity for discrimination of frailty status: baseline results of the Arizona frailty cohort study. Gerontology. 2015;61:258–67.CrossRefPubMed
24.
Brucki SMD, Nitrini R, Caramelli P, Bertolucci PHF, Okamoto IH. Suggestions for utilization of the mini-mental state examination in Brazil. Arq Neuropsiquiatr. 2003;61:777–81.CrossRefPubMed
25.
Paradela EMP, Lourenço RA, Veras RP. Validation of geriatric depression scale in a general outpatient clinic. Rev Saude Publica. 2005;39:918–23.CrossRefPubMed
26.
Benedetti TB, Mazo GZ, de Barros MV. Application of the international physical activity questionnaire (IPAQ) for evaluation of elderly women: concurrent validity and test-retest reproducibility. Rev Bras Ciênc Mov. 2004;12:25–34.
27.
Benedetti TRB, Antunes PDC, Rodriguez-Añez CR, Mazo GZ, Petroski ÉL. Reproducibilidad y validez del Cuestionario Internacional de Actividad Física (IPAQ) en hombres ancianos. Rev Bras Med Esporte. 2007;13:11–6.CrossRef
28.
29.
Rosenberg DE, Bull FC, Marshall AL, Sallis JF, Bauman AE. Assessment of sedentary behavior with the international physical activity questionnaire. J Phys Act Health. 2008;5:S30–44.CrossRefPubMed
30.
Santos DA, Virtuoso JS Jr, Meneguci J, Sasaki JE, Tribess S. Combined associations of physical activity and sedentary behavior with depressive symptoms in older adults. Issues Ment Health Nurs. 2017;38:272–6.PubMed
31.
32.
Garcia-Garcia FJ, Avila GG, Alfaro-Acha A, Andres MSA, Lanza MLAT, Aparicio MVE, et al. The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging. J Nutr Health Aging. 2011;15:852–6.CrossRefPubMed
33.
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet. 2013;381:752–62.CrossRefPubMed
34.
Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet. 2012;380:219–29.CrossRefPubMedCentralPubMed
35.
Win S, Parakh K, Eze-Nliam CM, Gottdiener JS, Kop WJ, Ziegelstein RC. Depressive symptoms, physical inactivity and risk of cardiovascular mortality in older adults: the cardiovascular health study. Heart. 2011;97:500–5.CrossRefPubMed
36.
de Rezende LF, Rey-Lopez JP, Matsudo VK, Luiz OC. Sedentary behavior and health outcomes among older adults: a systematic review. BMC Public Health. 2014;14:333.CrossRefPubMedCentralPubMed
37.
Ekelund U, Steene-Johannessen J, Brown WJ, Fagerland MW, Owen N, Powell KE, et al. Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. Lancet. 2016;388:1302–10.CrossRefPubMed
38.
Song J, Lindquist LA, Chang RW, Semanik PA, Ehrlich-Jones LS, Lee J, et al. Sedentary behavior as a risk factor for physical frailty independent of moderate activity: results from the osteoarthritis initiative. Am J Public Health. 2015;105:1439–45.CrossRefPubMedCentralPubMed
39.
Meneguci J, Santos DAT, Silva R, Santos RG, Sasaki JE, Tribess S, et al. Sedentary behavior: concept, physiological implications and the assessment procedure. Motricidade. 2015;11:160–74.CrossRef
40.
Nagai K, Tamaki K, Kusunoki H, Wada Y, Tsuji S, Ito M, et al. Isotemporal substitution of sedentary time with physical activity and its associations with frailty status. Clin Interv Aging. 2018;13:1831–6.CrossRefPubMedCentralPubMed
Metadata
Title
Association between frailty and the combination of physical activity level and sedentary behavior in older adults
Authors
Venicius Dantas da Silva
Sheilla Tribess
Joilson Meneguci
Jeffer Eidi Sasaki
Cíntia Aparecida Garcia-Meneguci
José Ailton Oliveira Carneiro
Jair Sindra Virtuoso Jr
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2019
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-019-7062-0

Other articles of this Issue 1/2019

BMC Public Health 1/2019 Go to the issue

Research article

Energy drinks and population health: consumption pattern and adverse effects among Saudi population

Research article

“It’s just in that sea of things that I never cared about”: perception of hepatitis B amongst university students in Aberdeen, North-East Scotland

Research article

Delay in treatment seeking and associated factors among suspected pulmonary tuberculosis patients in public health facilities of Adama town, eastern Ethiopia

Research article

Mortality pattern trends and disparities among Chinese from 2004 to 2016

Research article

A qualitative study of the process of adoption, implementation and enforcement of smoke-free policies in privately-owned affordable housing

Research article

Large-scale implementation of electronic Integrated Management of Childhood Illness (eIMCI) at the primary care level in Burkina Faso: a qualitative study on health worker perception of its medical content, usability and impact on antibiotic prescription and resistance