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Published in: BMC Public Health 1/2019

Open Access 01-12-2019 | Affective Disorder | Research article

Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis

Authors: Labanté Outcha Daré, Pierre-Emile Bruand, Daniel Gérard, Benoît Marin, Valerie Lameyre, Farid Boumédiène, Pierre-Marie Preux

Published in: BMC Public Health | Issue 1/2019

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Abstract

Background

As the data on the association of mental disorders and chronic physical diseases in developing and emerging countries is heterogeneous, this study aims to produce the first meta-analysis of these comorbidities.

Methodology

The meta-analysis protocol was registered in PROSPERO (N°CRD42017056521) and was performed in accordance with PRISMA guidelines. Initially, an article search was conducted on Medline, Embase, Lilacs and the Institut d’Epidémiologie et de Neurologie Tropicale database [Institute of Epidemiology and Tropical Neurology], as well as manually, with no restriction on language or date focusing on mental disorders, chronic diseases and neurotropic diseases. Two independent investigators assessed the quality of the studies which met the inclusion criteria using the Downs and Black assessment grid. The pooled estimates were calculated out using a random-effects method with CMA software Version 3.0. A meta-regression was then performed, and the significance level was set at 0.05.

Results

Of the 2604 articles identified, 40 articles involving 21,747 subjects met the inclusion criteria for co-morbidities between mental disorders and chronic physical diseases. Thirty-one articles were included in the meta-analysis of prevalence studies and 9 articles in that of the analytical studies. The pooled prevalence of mental disorders in patients with chronic physical diseases was 36.6% (95% CI, 31.4–42.1) and the pooled odds ratio was 3.1 (95% CI, 1.7–5.2). There was heterogeneity in all the estimates and in some cases, this was explained by the quality of the studies.

Conclusion

Some estimates regarding the prevalence of mental disorders in people with chronic physical diseases living in developing and emerging countries were similar to those in developed countries. Mental disorders are a burden in these countries. In order to respond effectively and efficiently to the morbidity and mortality associated with them, mental health care could be integrated with physical care.
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Metadata
Title
Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis
Authors
Labanté Outcha Daré
Pierre-Emile Bruand
Daniel Gérard
Benoît Marin
Valerie Lameyre
Farid Boumédiène
Pierre-Marie Preux
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2019
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-019-6623-6

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