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Published in: BMC Public Health 1/2018

Open Access 01-12-2018 | Research article

Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China

Authors: Jing Cui, Jianping Sun, Wei Wang, Nafeesa Yasmeen, Ma Ke, Hualei Xin, Qing Qiao, Aiguo Ma, Zulqarnain Baloch

Published in: BMC Public Health | Issue 1/2018

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Abstract

Background

To investigative the association of triglycerides (TG) and total cholesterol (TC) concentrations with impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) in Chinese adults.

Methods

The population-based cross-sectional diabetes survey was conducted in 2006 and 2009 in Qingdao, separately. 4400 participants (1 793 men and 2607 women) were include in current analysis. IFG/IGT was defined according to fasting plasma glucose (FPG) and/or 2 h post-load plasma glucose (2 h PG). Logistic regression models and areas under receiver operating characteristic curves (AUROC) were performed to estimate the associations between TG, TC levels and IFG/IGT.

Results

Spearman analysis showed that serum TG and TC was independently and positively associated with FPG and 2 h PG. As compared with normoglycaemia, the odds ratio[(95% confidence intervals), OR(95%CI)] for IFG/IGT corresponding to hypertriglyceridemia (HTG) were 1.61 (1. 17, 2. 22) in men and 1.57(1.15, 2.14) in women for TG and accompany with Hypercholesterolemia (HTC) 1.56 (1.15, 2.13) and 1. 20 (0.93, 1.54) for TC, when adjusting for confounding factor. The AUROCs of TG, TC for IFG/IGT were relatively smaller (0.50 < AUROC< 0. 7) in both gender. The optimal cut-offs for TG and TC was 1.61, 4.91 in men and 1. 24, 5. 32 in women, respectively.

Conclusions

Evaluated TG in both gender and TC in men were independently associated with the present of the IFG/IGT, yet, could not be an authentic predictors of IFG/IGT in both men and women in current Chinese population.
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Metadata
Title
Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China
Authors
Jing Cui
Jianping Sun
Wei Wang
Nafeesa Yasmeen
Ma Ke
Hualei Xin
Qing Qiao
Aiguo Ma
Zulqarnain Baloch
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2018
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-018-5286-z

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