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BMC Public Health
Published in: BMC Public Health 1/2017

Open Access 01-12-2017 | Research article

Childhood pesticide poisoning in Zhejiang, China: a retrospective analysis from 2006 to 2015

Authors: Aziguli Yimaer, Guangdi Chen, Meibian Zhang, Lifang Zhou, Xinglin Fang, Wei Jiang

Published in: BMC Public Health | Issue 1/2017

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Abstract

Background

Pesticide poisoning in children has been a serious public health issue around the world, especially in the developing countries where agriculture is still one of the largest economic sectors. The purpose of this study was to analyze epidemiological characteristics of acute pesticide poisoning in children from Zhejiang province, China.

Methods

The pesticide poisoning cases for children were retrieved from Occupational Disease Surveillance and Reporting System, Zhejiang Provincial Center for Disease Control and Prevention, China. The incident cases, deaths, and fatality rate of child pesticide poisoning from 2006 through 2015 were calculated.

Results

During the study period, totally 2952 children were poisoned by pesticides, with 66 deaths, resulting in a fatality rate of 2.24%. Among them, there were 1607 male cases with 28 deaths, and 1345 female cases with 38 deaths. Most of the cases occurred in preschool children (1349) and adolescent age group (1269). Organophosphate and carbamate insecticides were the cause of most poisonings (1130), leading to 34 deaths. The highest fatality rate (3.13%) was due to poisoning by herbicides and fungicides, causing 14 deaths out of 448 cases. Poisoning occurred mostly in rural areas (78%). And most pesticide poisoning occurred in the summer (896) and fall (811), while fewest poisoning cases in the winter (483) but with the highest fatality rate (3.52%).

Conclusions

This study shows that pesticide poisoning of children is a major health problem in Zhejiang, suggesting preventive strategies should be conducted to control childhood pesticide poisoning.
Literature
1.
Mostafalou S, Abdollahi M. Pesticides: an update of human exposure and toxicity. Arch Toxicol. 2017;91(2):549–99.
2.
Kim KH, Kabir E, Jahan SA. Exposure to pesticides and the associated human health effects. The Science of the total environment. 2017;575:525–35.
3.
4.
Moradi M, Ghaemi K, Mehrpour O. A hospital base epidemiology and pattern of acute adult poisoning across Iran: a systematic review. Electron physician. 2016;8(9):2860–70.CrossRefPubMedPubMedCentral
5.
Stallones L, Beseler CL. Assessing the connection between organophosphate pesticide poisoning and mental health: a comparison of neuropsychological symptoms from clinical observations, animal models and epidemiological studies. Cortex. 2016;74:405–16.CrossRefPubMed
6.
Zhang X, Zhao W, Jing R, Wheeler K, Smith GA, Stallones L, et al. Work-related pesticide poisoning among farmers in two villages of southern China: a cross-sectional survey. BMC Public Health. 2011;11:429.CrossRefPubMedPubMedCentral
7.
Azemi M, Berisha M, Kolgeci S, Bejiqi R. Frequency, etiology and several sociodemographic characteristics of acute poisoning in children treated in the intensive care unit. Materia socio-medica. 2012;24(2):76–80.CrossRefPubMedPubMedCentral
8.
Azab SM, Hirshon JM, Hayes BD, El-Setouhy M, Smith GS, Sakr ML, et al. Epidemiology of acute poisoning in children presenting to the poisoning treatment center at Ain Shams University in Cairo, Egypt, 2009-2013. Clin Toxicol. 2016;54(1):20–6.CrossRef
9.
Balme KH, Roberts JC, Glasstone M, Curling L, Rother HA, London L, et al. Pesticide poisonings at a tertiary children's hospital in South Africa: an increasing problem. Clin Toxicol. 2010;48(9):928–34.CrossRef
10.
Peshin SS, Srivastava A, Halder N, Gupta YK. Pesticide poisoning trend analysis of 13 years: a retrospective study based on telephone calls at the National Poisons Information Centre, all India Institute of Medical Sciences, New Delhi. J Forensic Legal Med. 2014;22:57–61.CrossRef
11.
12.
Liu J, Schelar E. Pesticide exposure and child neurodevelopment: summary and implications. Workplace health & safety. 2012;60(5):235–42. quiz 243
13.
14.
Chang VY, Davidson TB. Childhood exposures and risk of malignancy in adulthood. Pediatr Ann. 2015;44(11):e270–3.CrossRefPubMed
15.
16.
Raanan R, Harley KG, Balmes JR, Bradman A, Lipsett M, Eskenazi B. Early-life exposure to organophosphate pesticides and pediatric respiratory symptoms in the CHAMACOS cohort. Environ Health Perspect. 2015;123(2):179–85.PubMed
17.
18.
Kofman O, Berger A, Massarwa A, Friedman A, Jaffar AA. Motor inhibition and learning impairments in school-aged children following exposure to organophosphate pesticides in infancy. Pediatr Res. 2006;60(1):88–92.CrossRefPubMed
19.
Berghuis SA, Bos AF, Sauer PJ, Roze E. Developmental neurotoxicity of persistent organic pollutants: an update on childhood outcome. Arch Toxicol. 2015;89(5):687–709.CrossRefPubMed
20.
Eskenazi B, Marks AR, Bradman A, Harley K, Barr DB, Johnson C, et al. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ Health Perspect. 2007;115(5):792–8.CrossRefPubMedPubMedCentral
21.
Xu X, Nembhard WN, Kan H, Kearney G, Zhang ZJ, Talbott EO. Urinary trichlorophenol levels and increased risk of attention deficit hyperactivity disorder among US school-aged children. Occup Environ Med. 2011;68(8):557–61.CrossRefPubMedPubMedCentral
22.
Hou YH, Zhao Q, Wu YX, Hu TT, Chen Y, You YT, et al. An analysis of the clinical and epidemiological characteristics of acute poisoning patients in a general hospital. Zhonghua lao dong wei sheng zhi ye bing za zhi. 2016;34(7):506–9.
23.
Zhang X, Wu M, Yao H, Yang Y, Cui M, Tu Z, et al. Pesticide poisoning and neurobehavioral function among farm workers in Jiangsu, People's Republic of China. Cortex. 2016;74:396–404.CrossRefPubMed
24.
Li Y, Sun C, Qiu Z, Ma S, Yu X, Wang Z, et al. Clinical toxicology in China: current situation and future development. Clini toxicol. 2009;47(4):263–9.CrossRef
25.
Page A, Liu S, Gunnell D, Astell-Burt T, Feng X, Wang L, et al. Suicide by pesticide poisoning remains a priority for suicide prevention in China: analysis of national mortality trends 2006-2013. J Affect Disord. 2017;208:418–23.CrossRefPubMed
26.
Zhang M, Fang X, Zhou L, Su L, Zheng J, Jin M, et al. Pesticide poisoning in Zhejiang, China: a retrospective analysis of adult cases registration by occupational disease surveillance and reporting systems from 2006 to 2010. BMJ Open. 2013;3(11):e003510.CrossRefPubMedPubMedCentral
27.
Lin YR, Wu TK, Liu TA, Chou CC, Wu HP. Poison exposure and outcome of children admitted to a pediatric emergency department. WJP. 2011;7(2):143–9.PubMed
28.
Sun J, Guo X, Zhang J, Wang M, Jia C, Xu A. Incidence and fatality of serious suicide attempts in a predominantly rural population in Shandong, China: a public health surveillance study. BMJ Open. 2015;5(2):e006762.CrossRefPubMedPubMedCentral
29.
Senarathna L, Jayamanna SF, Kelly PJ, Buckley NA, Dibley MJ, Dawson AH. Changing epidemiologic patterns of deliberate self poisoning in a rural district of Sri Lanka. BMC Public Health. 2012;12:593.CrossRefPubMedPubMedCentral
30.
Cha ES, Khang YH, Lee WJ. Mortality from and incidence of pesticide poisoning in South Korea: findings from National Death and health utilization data between 2006 and 2010. PLoS One. 2014;9(4):e95299.CrossRefPubMedPubMedCentral
31.
Fortenberry GZ, Beckman J, Schwartz A, Prado JB, Graham LS, Higgins S, et al. Magnitude and characteristics of acute paraquat- and diquat-related illnesses in the US: 1998-2013. Environ Res. 2016;146:191–9.CrossRefPubMedPubMedCentral
32.
Hsieh YW, Lin JL, Lee SY, Weng CH, Yang HY, Liu SH, et al. Paraquat poisoning in pediatric patients. Pediatr Emerg Care. 2013;29(4):487–91.CrossRefPubMed
33.
Lee WJ, Ko Y, Cha ES. Acute pesticide poisoning among children in South Korea: findings from National Health Insurance claims data, 2006-2009. J Trop Pediatr. 2014;60(1):4–9.CrossRefPubMed
34.
Costet N, Pele F, Comets E, Rouget F, Monfort C, Bodeau-Livinec F, et al. Perinatal exposure to chlordecone and infant growth. Environ Res. 2015;142:123–34.CrossRefPubMed
35.
Forrester MB. Pediatric insecticide chalk exposures reported to Texas poison centers. Hum Exp Toxicol. 2013;32(5):554–8.CrossRefPubMed
36.
Trueblood AB, Forrester MB, Han D, Shipp EM, Cizmas LH. Pesticide-related poison center exposures in children and adolescents aged </=19 years in Texas, 2000-2013. Clin Toxicol. 2016;54(9):852–6.CrossRef
37.
Freeman NC, Hore P, Black K, Jimenez M, Sheldon L, Tulve N, et al. Contributions of children's activities to pesticide hand loadings following residential pesticide application. J Expo Anal Environ Epidemiol. 2005;15(1):81–8.CrossRefPubMed
38.
Ram P, Kanchan T, Unnikrishnan B. Pattern of acute poisonings in children below 15 years--a study from Mangalore, South India. J Forensic Legal Med. 2014;25:26–9.CrossRef
39.
Hawton K, Ratnayeke L, Simkin S, Harriss L, Scott V. Evaluation of acceptability and use of lockable storage devices for pesticides in Sri Lanka that might assist in prevention of self-poisoning. BMC Public Health. 2009;9:69.CrossRefPubMedPubMedCentral
40.
Gunnell D, Eddleston M, Phillips MR, Konradsen F. The global distribution of fatal pesticide self-poisoning: systematic review. BMC Public Health. 2007;7:357.CrossRefPubMedPubMedCentral
41.
Rajapakse T, Griffiths KM, Christensen H, Cotton S. A comparison of non-fatal self-poisoning among males and females, in Sri Lanka. BMC psychiatry. 2014;14:221.CrossRefPubMedPubMedCentral
42.
Gutierrez W, Cerda P, Plaza-Plaza JC, Mieres JJ, Paris E, Rios JC. Characterization of pesticide exposures reported between 2006 and 2013 to a poison information center in Chile. Revista medica de Chile. 2015;143(10):1269–76.CrossRefPubMed
43.
Kim K, Choi JW, Park M, Kim MS, Lee ES. A nationwide study of patients hospitalised for poisoning in Korea based on Korea National Hospital Discharge in-Depth Injury Survey data from 2005 to 2009. BMJ Open. 2015;5(11):e008823.CrossRefPubMedPubMedCentral
Metadata
Title
Childhood pesticide poisoning in Zhejiang, China: a retrospective analysis from 2006 to 2015
Authors
Aziguli Yimaer
Guangdi Chen
Meibian Zhang
Lifang Zhou
Xinglin Fang
Wei Jiang
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2017
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-017-4505-3

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