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Published in: BMC Public Health 1/2017

Open Access 01-12-2017 | Research article

Formulation of evidence-based messages to promote the use of physical activity to prevent and manage Alzheimer’s disease

Authors: Kathleen A. Martin Ginis, Jennifer Heisz, John C. Spence, Ilana B. Clark, Jordan Antflick, Chris I. Ardern, Christa Costas-Bradstreet, Mary Duggan, Audrey L. Hicks, Amy E. Latimer-Cheung, Laura Middleton, Kirk Nylen, Donald H. Paterson, Chelsea Pelletier, Michael A. Rotondi

Published in: BMC Public Health | Issue 1/2017

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Abstract

Background

The impending public health impact of Alzheimer’s disease is tremendous. Physical activity is a promising intervention for preventing and managing Alzheimer’s disease. However, there is a lack of evidence-based public health messaging to support this position. This paper describes the application of the Appraisal of Guidelines Research and Evaluation II (AGREE-II) principles to formulate an evidence-based message to promote physical activity for the purposes of preventing and managing Alzheimer’s disease.

Methods

A messaging statement was developed using the AGREE-II instrument as guidance. Methods included (a) conducting a systematic review of reviews summarizing research on physical activity to prevent and manage Alzheimer’s disease, and (b) engaging stakeholders to deliberate the evidence and formulate the messaging statement.

Results

The evidence base consisted of seven systematic reviews focused on Alzheimer’s disease prevention and 20 reviews focused on symptom management. Virtually all of the reviews of symptom management conflated patients with Alzheimer’s disease and patients with other dementias, and this limitation was reflected in the second part of the messaging statement. After deliberating the evidence base, an expert panel achieved consensus on the following statement: “Regular participation in physical activity is associated with a reduced risk of developing Alzheimer’s disease. Among older adults with Alzheimer’s disease and other dementias, regular physical activity can improve performance of activities of daily living and mobility, and may improve general cognition and balance.” The statement was rated favourably by a sample of older adults and physicians who treat Alzheimer’s disease patients in terms of its appropriateness, utility, and clarity.

Conclusion

Public health and other organizations that promote physical activity, health and well-being to older adults are encouraged to use the evidence-based statement in their programs and resources. Researchers, clinicians, people with Alzheimer’s disease and caregivers are encouraged to adopt the messaging statement and the recommendations in the companion informational resource.
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Metadata
Title
Formulation of evidence-based messages to promote the use of physical activity to prevent and manage Alzheimer’s disease
Authors
Kathleen A. Martin Ginis
Jennifer Heisz
John C. Spence
Ilana B. Clark
Jordan Antflick
Chris I. Ardern
Christa Costas-Bradstreet
Mary Duggan
Audrey L. Hicks
Amy E. Latimer-Cheung
Laura Middleton
Kirk Nylen
Donald H. Paterson
Chelsea Pelletier
Michael A. Rotondi
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2017
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-017-4090-5

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