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Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Penile cancer treatment costs in England

Authors: Sam T. Keeping, Michael J. Tempest, Stephanie J. Stephens, Stuart M. Carroll, Vijay K Sangar

Published in: BMC Public Health | Issue 1/2015

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Abstract

Background

Penile cancer is a rare malignancy in Western countries, with an incidence rate of around 1 per 100,000. Due to its rarity, most treatment recommendations are based on small trials and case series reports. Furthermore, data on the resource implications are scarce. The objective of this study was to estimate the annual economic burden of treating penile cancer in England between 2006 and 2011 and the cost of treating a single case based on a modified version of the European Association of Urology penile cancer treatment guidelines.

Methods

A retrospective (non-comparative) case series was performed using data extracted from Hospital Episode Statistics. Patient admission data for invasive penile cancer or carcinoma in situ of the penis was extracted by ICD-10 code and matched to data from the 2010/11 National Tariff to calculate the mean number of patients and associated annual cost. A mathematical model was simultaneously developed to estimate mean treatment costs per patient based on interventions and their associated outcomes, advised under a modified version of the European Association of Urologists Treatment Guidelines.

Results

Approximately 640 patients per year received some form of inpatient care between 2006 and 2011, amounting to an average of 1,292 spells of care; with an average of 48 patients being treated in an outpatient setting. Mean annual costs per invasive penile cancer inpatient and outpatient were £3,737 and £1,051 respectively, with total mean annual costs amounting to £2,442,020 (excluding high cost drugs). The mean cost per case, including follow-up, was estimated to be £7,421 to £8,063. Results were sensitive to the setting in which care was delivered.

Conclusions

The treatment of penile cancer consumes similar levels of resource to other urological cancers. This should be factored in to decisions concerning new treatment modalities as well as choices around resource allocation in specialist treatment centres and the value of preventative measures.
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Literature
1.
go back to reference Parkin DM, Bray F. Chapter 2: The burden of HPV-related cancers. Vaccine. 2006;24 Suppl 3:S3/11–25. Parkin DM, Bray F. Chapter 2: The burden of HPV-related cancers. Vaccine. 2006;24 Suppl 3:S3/11–25.
2.
go back to reference Bleeker MCG, Heideman D a M, Snijders PJF, Horenblas S, Dillner J, Meijer CJLM. Penile cancer: epidemiology, pathogenesis and prevention. World J Urol. 2009;27:141–50.CrossRefPubMed Bleeker MCG, Heideman D a M, Snijders PJF, Horenblas S, Dillner J, Meijer CJLM. Penile cancer: epidemiology, pathogenesis and prevention. World J Urol. 2009;27:141–50.CrossRefPubMed
3.
go back to reference Arya M, Li R, Pegler K, Sangar V, Kelly JD, Minhas S, et al. Long-term trends in incidence, survival and mortality of primary penile cancer in England. Cancer Causes Control. 2013;24:2169–76.CrossRefPubMed Arya M, Li R, Pegler K, Sangar V, Kelly JD, Minhas S, et al. Long-term trends in incidence, survival and mortality of primary penile cancer in England. Cancer Causes Control. 2013;24:2169–76.CrossRefPubMed
4.
go back to reference Leijte JAP, Kirrander P, Antonini N, Windahl T, Horenblas S. Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients. Eur Urol. 2008;54:161–8.CrossRefPubMed Leijte JAP, Kirrander P, Antonini N, Windahl T, Horenblas S. Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients. Eur Urol. 2008;54:161–8.CrossRefPubMed
5.
go back to reference Anic GM, Giuliano AR. Genital HPV infection and related lesions in men. Prev Med (Baltim). 2011;53 Suppl 1:S36–41.CrossRef Anic GM, Giuliano AR. Genital HPV infection and related lesions in men. Prev Med (Baltim). 2011;53 Suppl 1:S36–41.CrossRef
6.
go back to reference Dillner J, von Krogh G, Horenblas S, Meijer CJ. Etiology of squamous cell carcinoma of the penis. Scand J Urol Nephrol Suppl. 2000;189–93. Dillner J, von Krogh G, Horenblas S, Meijer CJ. Etiology of squamous cell carcinoma of the penis. Scand J Urol Nephrol Suppl. 2000;189–93.
7.
go back to reference Miralles-Guri C, Bruni L, Cubilla AL, Castellsagué X, Bosch FX, de Sanjosé S. Human papillomavirus prevalence and type distribution in penile carcinoma. J Clin Pathol. 2009;62:870–8.CrossRefPubMed Miralles-Guri C, Bruni L, Cubilla AL, Castellsagué X, Bosch FX, de Sanjosé S. Human papillomavirus prevalence and type distribution in penile carcinoma. J Clin Pathol. 2009;62:870–8.CrossRefPubMed
8.
go back to reference Solsona E, Algaba F, Horenblas S, Pizzocaro G, Windahl T. EAU Guidelines on Penile Cancer. Eur Urol. 2004;46:1–8.CrossRefPubMed Solsona E, Algaba F, Horenblas S, Pizzocaro G, Windahl T. EAU Guidelines on Penile Cancer. Eur Urol. 2004;46:1–8.CrossRefPubMed
9.
go back to reference Maddineni SB, Lau MM, Sangar VK. Identifying the needs of penile cancer sufferers: a systematic review of the quality of life, psychosexual and psychosocial literature in penile cancer. BMC Urol. 2009;9:8.CrossRefPubMedPubMedCentral Maddineni SB, Lau MM, Sangar VK. Identifying the needs of penile cancer sufferers: a systematic review of the quality of life, psychosexual and psychosocial literature in penile cancer. BMC Urol. 2009;9:8.CrossRefPubMedPubMedCentral
16.
go back to reference Pizzocaro G, Algaba F, Horenblas S, Solsona E, Tana S, Van Der Poel H, et al. EAU penile cancer guidelines 2009. Eur Urol. 2010;57:1002–12.CrossRefPubMed Pizzocaro G, Algaba F, Horenblas S, Solsona E, Tana S, Van Der Poel H, et al. EAU penile cancer guidelines 2009. Eur Urol. 2010;57:1002–12.CrossRefPubMed
18.
go back to reference Sangar VK, Ragavan N, Matanhelia SS, Watson MW, Blades RA. The economic consequences of prostate and bladder cancer in the UK. BJU Int. 2005;95:59–63.CrossRefPubMed Sangar VK, Ragavan N, Matanhelia SS, Watson MW, Blades RA. The economic consequences of prostate and bladder cancer in the UK. BJU Int. 2005;95:59–63.CrossRefPubMed
Metadata
Title
Penile cancer treatment costs in England
Authors
Sam T. Keeping
Michael J. Tempest
Stephanie J. Stephens
Stuart M. Carroll
Vijay K Sangar
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-2669-2

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