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BMC Public Health
Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Prevalence of depressive symptoms and factors associated with it in type 2 diabetic patients: a cross-sectional study in China

Authors: Linchuang Wang, Rui Song, Zhigang Chen, Jun Wang, Feng Ling

Published in: BMC Public Health | Issue 1/2015

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Abstract

Background

Depressive symptoms in patients with type 2 diabetes mellitus (T2DM) have attracted much attention in recent years, and negatively affect the health of diabetic patients in numerous ways. This study evaluated the prevalence rate of depressive symptoms in T2DM patients in Shanghai, and the potential factors that may be associated with depressive symptoms in this select population.

Methods

A total of 865 T2DM patients were recruited from Longhua Street, Xuhui, Shanghai by simple random sampling, and all the patients were assessed with the Zung Self-rating Depression Scale to screen for depressive symptoms. Factors associated with depressive symptoms were analyzed by logistic regression.

Results

Among the 865 patients (403 were male, 462 were female, average age 70.13 ± 20.33 years), 304 (35.1%) patients were categorized as having depressive symptoms. Rates of myocardial infarction and stress in one month were higher in the depressive symptoms group than in the non-depressive symptoms group by the X 2 test. Rates of patients having a job, having a college education or above, and sleeping less than 7 h/24 h day were also higher in the depressive symptoms group by the X 2 test. Body mass index, and levels of total cholesterol, triglyceride, urea, creatinine, uric acid, and homocysteine were higher in the depressive symptoms group by the independent samples t test and non-parametric test. Sleeping hours, history of myocardial infarction, stress in one month, working status, and total cholesterol were significantly associated with depressive symptoms (p < 0.05).

Conclusions

In the Chinese population analyzed in this study, the prevalence rate of depressive symptoms in patients with T2DM was high. Further research on the relationship between diabetes and depressive symptoms is necessary in a wider Chinese population.
Literature
1.
Khuwaja AK, Lalani S, Dhanani R, Azam IS, Rafique G, White F. Anxiety and depression among outpatients with type 2 diabetes: a multi-centre study of prevalence and associated factors. Diabetol Metab Syndr. 2010;2:72.CrossRefPubMedPubMedCentral
2.
Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care. 2001;24(6):1069–78.CrossRefPubMed
3.
Aarts S, van den Akker M, van Boxtel MP, Jolles J, Winkens B, Metsemakers JF. Diabetes mellitus type II as a risk factor for depression: a lower than expected risk in a general practice setting. Eur J Epidemiol. 2009;24(10):641–8.CrossRefPubMedPubMedCentral
4.
Katon WJ, Rutter C, Simon G, Lin EH, Ludman E, Ciechanowski P, et al. The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care. 2005;28(11):2668–72.CrossRefPubMed
5.
Lin EH, Heckbert SR, Rutter CM, Katon WJ, Ciechanowski P, Ludman EJ, et al. Depression and increased mortality in diabetes: unexpected causes of death. Ann Fam Med. 2009;7(5):414–21.CrossRefPubMedPubMedCentral
6.
Katon W, Fan MY, Unutzer J, Taylor J, Pincus H, Schoenbaum M. Depression and diabetes: a potentially lethal combination. J Gen Intern Med. 2008;23(10):1571–5.CrossRefPubMedPubMedCentral
7.
Gonzalez JS, Safren SA, Cagliero E, Wexler DJ, Delahanty L, Wittenberg E, et al. Depression, self-care, and medication adherence in type 2 diabetes: relationships across the full range of symptom severity. Diabetes Care. 2007;30(9):2222–7.CrossRefPubMedPubMedCentral
8.
Katon W, Lyles CR, Parker MM, Karter AJ, Huang ES, Whitmer RA. Association of depression with increased risk of dementia in patients with type 2 diabetes: the Diabetes and Aging Study. Arch Gen Psychiatry. 2012;69(4):410–7.CrossRefPubMed
9.
Himelhoch S, Weller WE, Wu AW, Anderson GF, Cooper LA. Chronic medical illness, depression, and use of acute medical services among Medicare beneficiaries. Med Care. 2004;42(6):512–21.CrossRefPubMed
10.
Simon GE, Katon WJ, Lin EH, Ludman E, VonKorff M, Ciechanowski P, et al. Diabetes complications and depression as predictors of health service costs. Gen Hosp Psychiatry. 2005;27(5):344–51.CrossRefPubMed
11.
Kimbro LB, Mangione CM, Steers WN, Duru OK, McEwen L, Karter A, et al. Depression and all-cause mortality in persons with diabetes mellitus: are older adults at higher risk? Results from the translating research into action for diabetes study. J Am Geriatr Soc. 2014;62(6):1017–22.CrossRefPubMedPubMedCentral
12.
Pouwer F. Should we screen for emotional distress in type 2 diabetes mellitus? Nat Rev Endocrinol. 2009;5(12):665–71.CrossRefPubMed
13.
Bouwman V, Adriaanse MC, Van TRE, Snoek FJ, Dekker JM, Nijpels G. Depression, anxiety and glucose metabolism in the general dutch population: the new Hoorn study. PLoS One. 2010;5(4):e9971.CrossRefPubMedPubMedCentral
14.
Liu Y, Maier M, Hao Y, Chen Y, Qin Y, Huo R. Factors related to quality of life for patients with type 2 diabetes with or without depressive symptoms - results from a community-based study in China. J Clin Nurs. 2013;22(1–2):80–8.CrossRefPubMed
15.
Shiotani I, Sato H, Kinjo K, Nakatani D, Mizuno H, Ohnishi Y, et al. Depressive symptoms predict 12-month prognosis in elderly patients with acute myocardial infarction. J Cardiovasc Risk. 2002;9(3):153–60.CrossRefPubMed
16.
Talbot F, Nouwen A. A review of the relationship between depression and diabetes in adults: is there a link? Diabetes Care. 2000;23(10):1556–62.CrossRefPubMed
17.
Charney DS, Reynolds CR, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, et al. Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry. 2003;60(7):664–72.CrossRefPubMed
18.
Lebowitz BD, Pearson JL, Schneider LS, Reynolds CR, Alexopoulos GS, Bruce ML, et al. Diagnosis and treatment of depression in late life. Consensus statement update. JAMA. 1997;278(14):1186–90.CrossRefPubMed
19.
de Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ. Association of depression and diabetes complications: a meta-analysis. Psychosom Med. 2001;63(4):619–30.CrossRefPubMed
20.
Fortes C, Farchi S, Forastiere F, Agabiti N, Pacifici R, Zuccaro P, et al. Depressive symptoms lead to impaired cellular immune response. Psychother Psychosom. 2003;72(5):253–60.CrossRefPubMed
21.
Katon W, Ciechanowski P. Impact of major depression on chronic medical illness. J Psychosom Res. 2002;53(4):859–63.CrossRefPubMed
22.
Bogner HR, Morales KH, Post EP, Bruce ML. Diabetes, depression, and death: a randomized controlled trial of a depression treatment program for older adults based in primary care (PROSPECT). Diabetes Care. 2007;30(12):3005–10.CrossRefPubMedPubMedCentral
23.
Engum A, Mykletun A, Midthjell K, Holen A, Dahl AA. Depression and diabetes: a large population-based study of sociodemographic, lifestyle, and clinical factors associated with depression in type 1 and type 2 diabetes. Diabetes Care. 2005;28(8):1904–9.CrossRefPubMed
Metadata
Title
Prevalence of depressive symptoms and factors associated with it in type 2 diabetic patients: a cross-sectional study in China
Authors
Linchuang Wang
Rui Song
Zhigang Chen
Jun Wang
Feng Ling
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-1567-y

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