Skip to main content
Top
Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Risk factors of impaired fasting glucose and type 2 diabetes in Yaoundé, Cameroon: a cross sectional study

Authors: Clement Nyuyki Kufe, Kerstin Klipstein-Grobusch, Fezeu Leopold, Felix Assah, George Ngufor, George Mbeh, Vivian Nchanchou Mbanya, Jean Claude Mbanya

Published in: BMC Public Health | Issue 1/2015

Login to get access

Abstract

Background

The prevalence of diabetes is increasing worldwide, particularly in low and middle income countries, where treatment and control are often unavailable and inaccessible. Information on risk factors at local and regional levels is of utmost importance for tailored prevention programmes to curb the rise in diabetes.
The current study was undertaken to investigate the prevalence of Impaired Fasting Glucose (IFG)/Type 2 Diabetes (T2D) and its risk factors in the adult population in Biyem-Assi-Yaoundé, Cameroon.

Methods

Information on cardiovascular risk factors using the WHO STEPwise approach was obtained for 1623 men and women aged 25 years and older of the CAMBoD Project in Biyem-Assi, Yaoundé, Cameroon. T2D was defined as fasting capillary glucose (FCG) ≥ 7.0 mmol/l and/or being on diabetes medication, IFG/T2D as FCG ≥ 6.1 mmol/l and/or being on diabetes medication. Descriptive statistics and multivariate logistic regression analyses were used to describe prevalence of IFG/T2D, prevalence of risk factors for IFG/T2D and to investigate the association of risk factors with prevalence of IFG/T2D.

Results

Prevalence of T2D and of IFG/T2D was 3.3% and 5.7%. Prevalence of hypertension, obesity and abdominal obesity (elevated waist circumference) was 26.6%, 28.4% and 34.9%, respectively. Age and abdominal obesity were significantly associated with IFG/T2D in multivariate logistic regression.

Conclusion

For successful primary prevention of T2D in the general population in Cameroon tailored efforts to address obesity, particularly abdominal obesity, and associated life-style factors are warranted.
Literature
1.
go back to reference World Health Organization Global Program on Evidence for Health Policy. National burden of disease studies, A practical guide, edition 2.0. 2001. World Health Organization Global Program on Evidence for Health Policy. National burden of disease studies, A practical guide, edition 2.0. 2001.
2.
go back to reference International Diabetes Federation. Diabetes Atlas. 6th ed. 2013. International Diabetes Federation. Diabetes Atlas. 6th ed. 2013.
3.
go back to reference Hall V, Thomson RW, Henriksen O, Loshe N. Diabetes in Sub Saharan Africa 1999-2011: epidemiology and public health implications. A systematic review. BMC Public Health. 2011;11:564.CrossRefPubMedPubMedCentral Hall V, Thomson RW, Henriksen O, Loshe N. Diabetes in Sub Saharan Africa 1999-2011: epidemiology and public health implications. A systematic review. BMC Public Health. 2011;11:564.CrossRefPubMedPubMedCentral
4.
go back to reference Mbanya JC, Motala AA, Sobngwi E, Assah FK, Enoru ST. Diabetes in sub-Saharan Africa. Lancet. 2010;375(9733):2254–66.CrossRefPubMed Mbanya JC, Motala AA, Sobngwi E, Assah FK, Enoru ST. Diabetes in sub-Saharan Africa. Lancet. 2010;375(9733):2254–66.CrossRefPubMed
5.
go back to reference Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia. Report of a WHO/IDF consultation. 2006. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia. Report of a WHO/IDF consultation. 2006.
6.
go back to reference International Diabetes Federation. Diabetes Atlas. 3rd ed. 2006. International Diabetes Federation. Diabetes Atlas. 3rd ed. 2006.
7.
go back to reference International Diabetes Federation. Diabetes Atlas. 4th ed. 2009. International Diabetes Federation. Diabetes Atlas. 4th ed. 2009.
8.
go back to reference Unwin N, Shaw J, Zimmet P, Alberti GMM. International diabetes federation IGT/IFG consensus statement. Diabet Med. 2002;19:708–23.CrossRefPubMed Unwin N, Shaw J, Zimmet P, Alberti GMM. International diabetes federation IGT/IFG consensus statement. Diabet Med. 2002;19:708–23.CrossRefPubMed
9.
go back to reference Nathan DM, Davidson MB, DeFronzo RA, Heine RJ, Henry RR, Pratley R, et al. Impaired fasting glucose and impaired glucose tolerance. Implications of care. Diabetes Care. 2007;30(3):753–9.CrossRefPubMed Nathan DM, Davidson MB, DeFronzo RA, Heine RJ, Henry RR, Pratley R, et al. Impaired fasting glucose and impaired glucose tolerance. Implications of care. Diabetes Care. 2007;30(3):753–9.CrossRefPubMed
10.
go back to reference Kamadjeu RM, Edwards R, Atanga JS, Unwin N, Kiawi EC, Mbanya JC. Prevalence, awareness and management of hypertension in Cameroon: findings of the 2003 Cameroon burden of diabetes baseline survey. J Hum Hyperten. 2006;20:91–2.CrossRef Kamadjeu RM, Edwards R, Atanga JS, Unwin N, Kiawi EC, Mbanya JC. Prevalence, awareness and management of hypertension in Cameroon: findings of the 2003 Cameroon burden of diabetes baseline survey. J Hum Hyperten. 2006;20:91–2.CrossRef
11.
go back to reference Kiawi E, Edwards R, Shu J, Unwin N, Kamadjeu R, Mbanya JC. Knowledge, attitudes, and behavior relating to diabetes and its main risk factors among urban residents in Cameroon: a qualitative survey. Ethn Dis. 2006;16:503–9.PubMed Kiawi E, Edwards R, Shu J, Unwin N, Kamadjeu R, Mbanya JC. Knowledge, attitudes, and behavior relating to diabetes and its main risk factors among urban residents in Cameroon: a qualitative survey. Ethn Dis. 2006;16:503–9.PubMed
12.
go back to reference Cartographie des formations sanitaires au Cameroon. Ministry of public health Cameroon 2011. 2011. Cartographie des formations sanitaires au Cameroon. Ministry of public health Cameroon 2011. 2011.
13.
go back to reference Sobngwi E, Mbanya J-CN, Unwin NC, Kengne AP, Fezeu L, Minkoulou EM, et al. Physical activity and its relationship with obesity, hypertension and diabetes in urban and rural Cameroon. Int J Obes. 2002;26:1009–16.CrossRef Sobngwi E, Mbanya J-CN, Unwin NC, Kengne AP, Fezeu L, Minkoulou EM, et al. Physical activity and its relationship with obesity, hypertension and diabetes in urban and rural Cameroon. Int J Obes. 2002;26:1009–16.CrossRef
14.
go back to reference Ashworth L, Gibb I, Alberti KGMM. HemoCue: evaluation of a portable photometric system for determining glucose in whole blood. Clin Chem. 1992;38:1479–82.PubMed Ashworth L, Gibb I, Alberti KGMM. HemoCue: evaluation of a portable photometric system for determining glucose in whole blood. Clin Chem. 1992;38:1479–82.PubMed
15.
go back to reference HemoCue™ Hb 201DM System Photometer Operating Manual. Angelhom, Sweden: HemoCue AB; 2005. HemoCue™ Hb 201DM System Photometer Operating Manual. Angelhom, Sweden: HemoCue AB; 2005.
16.
go back to reference World Health Organization. WHO STEPS surveillance manual: the WHO STEPwise approach to chronic disease risk factor surveillance. Geneva: World Health Organization; 2005. World Health Organization. WHO STEPS surveillance manual: the WHO STEPwise approach to chronic disease risk factor surveillance. Geneva: World Health Organization; 2005.
17.
go back to reference Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC7 report (published correction appears in JAMA;290[2]:197). JAMA. 2003;289:2560–72.CrossRefPubMed Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC7 report (published correction appears in JAMA;290[2]:197). JAMA. 2003;289:2560–72.CrossRefPubMed
18.
go back to reference Gallagher D, Visser M, Sepulveda D, Pierson RN, Harris T, Heymsfield SB. How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? Am J Epidemiol. 1996;143:228–39.CrossRefPubMed Gallagher D, Visser M, Sepulveda D, Pierson RN, Harris T, Heymsfield SB. How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? Am J Epidemiol. 1996;143:228–39.CrossRefPubMed
19.
go back to reference WHO. Physical status: the use and interpretation of anthropometry, Report of a WHO expert committee. WHO technical report series 854. 1995. WHO. Physical status: the use and interpretation of anthropometry, Report of a WHO expert committee. WHO technical report series 854. 1995.
20.
go back to reference WHO. Obesity: preventing and managing the global epidemic, Report of a WHO consultation. WHO technical report series 894. 2000. WHO. Obesity: preventing and managing the global epidemic, Report of a WHO consultation. WHO technical report series 894. 2000.
21.
go back to reference Östman J, Britton M, Jonsson E. Treating and preventing obesity. Kga, Weinheim: WILEY-VCH Verlag GmbH & Co; 2004.CrossRef Östman J, Britton M, Jonsson E. Treating and preventing obesity. Kga, Weinheim: WILEY-VCH Verlag GmbH & Co; 2004.CrossRef
22.
go back to reference Mamtani MR, Kulkarni HR. Predictive performance of anthropometric indexes of central obesity for the risk of type 2 diabetes. Arch Med Res. 2005;3:581–9.CrossRef Mamtani MR, Kulkarni HR. Predictive performance of anthropometric indexes of central obesity for the risk of type 2 diabetes. Arch Med Res. 2005;3:581–9.CrossRef
24.
go back to reference Ahmad OB, Boschi-Pinto C, Lopez AD, Murray CJL, Lozano R, Inoue M. Age standardization of rates: a New WHO standard. GPE discussion paper series: No.31. Geneva: World Health Organisation; 2001. Ahmad OB, Boschi-Pinto C, Lopez AD, Murray CJL, Lozano R, Inoue M. Age standardization of rates: a New WHO standard. GPE discussion paper series: No.31. Geneva: World Health Organisation; 2001.
25.
go back to reference Peer N, Kengne AP, Motala AA, Mbanya JC. Diabetes in the Africa region: an update. Diabetes Res Clin Pract. 2013;103:197–205.CrossRefPubMed Peer N, Kengne AP, Motala AA, Mbanya JC. Diabetes in the Africa region: an update. Diabetes Res Clin Pract. 2013;103:197–205.CrossRefPubMed
26.
go back to reference Nsakashalo-Senkwe M, Siziya S, Goma FM, Songolo P, Mukonka V, Babaniyi O. Combined prevalence of impaired glucose level or diabetes and its correlates in Lusaka Urban district. Zambia: a population based survey. Int Arch Med. 2011;4:2.CrossRefPubMedPubMedCentral Nsakashalo-Senkwe M, Siziya S, Goma FM, Songolo P, Mukonka V, Babaniyi O. Combined prevalence of impaired glucose level or diabetes and its correlates in Lusaka Urban district. Zambia: a population based survey. Int Arch Med. 2011;4:2.CrossRefPubMedPubMedCentral
27.
go back to reference Gu D, Reynolds K, Duan X, Xin X, Chen J, Wu X, et al. Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterAsia). Diabetologia. 2003;46:1190–8.CrossRefPubMed Gu D, Reynolds K, Duan X, Xin X, Chen J, Wu X, et al. Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterAsia). Diabetologia. 2003;46:1190–8.CrossRefPubMed
28.
go back to reference Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New Engl J Med. 2001;344:1343–50.CrossRefPubMed Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New Engl J Med. 2001;344:1343–50.CrossRefPubMed
29.
go back to reference Knowler WC, Barrett-Connor E, Fowler SE, Hammon RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with life style intervention or metformin. N Engl J Med. 2002;346:393–403.CrossRefPubMed Knowler WC, Barrett-Connor E, Fowler SE, Hammon RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with life style intervention or metformin. N Engl J Med. 2002;346:393–403.CrossRefPubMed
30.
go back to reference Cowie CC, Rust KF, Byrd-Holt DD, Flegal KM, Engelgau MM, Saydah SH, et al. Prevalence of diabetes and impaired fasting glucose in adults in the US population: national health and nutrition examination survey 1999-2002. Diabetes Care. 2006;29:1263–8.CrossRefPubMed Cowie CC, Rust KF, Byrd-Holt DD, Flegal KM, Engelgau MM, Saydah SH, et al. Prevalence of diabetes and impaired fasting glucose in adults in the US population: national health and nutrition examination survey 1999-2002. Diabetes Care. 2006;29:1263–8.CrossRefPubMed
31.
go back to reference Hilawe EH, Yatsuya H, Kawaguchi L, Aoyama A. Differences by sex in the prevalence of diabetes mellitus, impaired fasting glycemia and impaired glucose tolerance in sub-Saharan Africa: a systematic review and meta-analysis. Bull World Health Organ. 2013;91:671–682D.CrossRefPubMedPubMedCentral Hilawe EH, Yatsuya H, Kawaguchi L, Aoyama A. Differences by sex in the prevalence of diabetes mellitus, impaired fasting glycemia and impaired glucose tolerance in sub-Saharan Africa: a systematic review and meta-analysis. Bull World Health Organ. 2013;91:671–682D.CrossRefPubMedPubMedCentral
32.
go back to reference Fezeu L, Balkau B, Sobngwi E, Kengne AP, Vol S, Ducimetiere P, et al. Waist circumference and obesity-related abnormalities in French and Cameroonian adults: the role of urbanization and ethnicity. Int J Obes. 2010;34:446–53.CrossRef Fezeu L, Balkau B, Sobngwi E, Kengne AP, Vol S, Ducimetiere P, et al. Waist circumference and obesity-related abnormalities in French and Cameroonian adults: the role of urbanization and ethnicity. Int J Obes. 2010;34:446–53.CrossRef
33.
34.
go back to reference Villegas R, Shu XO, Gao YT, Yang, Elasy T, Li H, et al. Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese women. J Nutr. 2008;138:574–80.PubMedPubMedCentral Villegas R, Shu XO, Gao YT, Yang, Elasy T, Li H, et al. Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese women. J Nutr. 2008;138:574–80.PubMedPubMedCentral
35.
go back to reference Beulens JW, van der Schouw YT, Bergmann MM, Rohrmann S, Schulze MB, Buijsse B, et al. Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size. The EPIC–inter act study. J Intern Med. 2012;272(4):358–70.CrossRefPubMed Beulens JW, van der Schouw YT, Bergmann MM, Rohrmann S, Schulze MB, Buijsse B, et al. Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size. The EPIC–inter act study. J Intern Med. 2012;272(4):358–70.CrossRefPubMed
36.
go back to reference Helmrich SP, Ragland DR, Leung RW, Paffenbarger Jr RS. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med. 1991;325:147–52.CrossRefPubMed Helmrich SP, Ragland DR, Leung RW, Paffenbarger Jr RS. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med. 1991;325:147–52.CrossRefPubMed
37.
go back to reference Helmrich SP, Ragland DR, Paffenbarger Jr RS. Prevention of non-insulin-dependent diabetes mellitus with physical activity. Med Sci Sports Exerc. 1994;26:824–30.CrossRefPubMed Helmrich SP, Ragland DR, Paffenbarger Jr RS. Prevention of non-insulin-dependent diabetes mellitus with physical activity. Med Sci Sports Exerc. 1994;26:824–30.CrossRefPubMed
38.
go back to reference Hu G, Qiao Q, Silventoinen K, Eriksson JG, Jousilahti P, Lindström J, et al. Occupational, commuting, and leisure-time physical activity in relation to risk for type 2 diabetes in middle-aged Finnish men and women. Diabetologia. 2003;46(3):322–9.CrossRefPubMed Hu G, Qiao Q, Silventoinen K, Eriksson JG, Jousilahti P, Lindström J, et al. Occupational, commuting, and leisure-time physical activity in relation to risk for type 2 diabetes in middle-aged Finnish men and women. Diabetologia. 2003;46(3):322–9.CrossRefPubMed
Metadata
Title
Risk factors of impaired fasting glucose and type 2 diabetes in Yaoundé, Cameroon: a cross sectional study
Authors
Clement Nyuyki Kufe
Kerstin Klipstein-Grobusch
Fezeu Leopold
Felix Assah
George Ngufor
George Mbeh
Vivian Nchanchou Mbanya
Jean Claude Mbanya
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-1413-2

Other articles of this Issue 1/2015

BMC Public Health 1/2015 Go to the issue